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MFATCGAGVTITGPDALTERFVRETEPVRDFLIRNAIRLTHQRADAEDLVQETLLKAYLSFGRYREGNHL KAWLARIMSNAWIDRHRSAQRRPAEQLSAEMADLRFSTEMPSAGRGWVDSAETQALQSMPGDAGIALAML PPELRDIVYYACVADYRNTEIAVLLGIPVGTVGSRLHRGKALLREALSHSTDNDQAPGERRMAG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1747 | - | - | 100% (204) | RNA polymerase sigma-70 factor |
| M. smegmatis MC2 155 | MSMEG_1690 | - | 6e-36 | 45.36% (194) | putative ECF sigma factor RpoE1 |
| M. smegmatis MC2 155 | MSMEG_1914 | - | 1e-34 | 44.51% (173) | RNA polymerase sigma-70 factor, family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3250c | sigH | 2e-34 | 42.19% (192) | RNA polymerase sigma factor RpoE |
| M. gilvum PYR-GCK | Mflv_4689 | - | 2e-34 | 44.15% (188) | ECF subfamily RNA polymerase sigma-24 factor |
| M. tuberculosis H37Rv | Rv3223c | sigH | 2e-34 | 42.19% (192) | RNA polymerase sigma factor RpoE |
| M. leprae Br4923 | MLBr_01076 | sigE | 3e-15 | 33.54% (161) | RNA polymerase sigma factor SigE |
| M. abscessus ATCC 19977 | MAB_3543c | - | 1e-34 | 46.47% (170) | RNA polymerase sigma-E factor |
| M. marinum M | MMAR_1334 | sigH | 1e-34 | 44.57% (175) | alternative RNA polymerase sigma-E factor (sigma- 24) SigH |
| M. avium 104 | MAV_4171 | - | 2e-34 | 45.09% (173) | RNA polymerase sigma factor RpoE |
| M. thermoresistible (build 8) | TH_0665 | sigH | 1e-32 | 43.35% (173) | ALTERNATIVE RNA POLYMERASE SIGMA-E FACTOR (SIGMA-24) SIGH |
| M. ulcerans Agy99 | MUL_2545 | sigH | 7e-34 | 44.00% (175) | RNA polymerase sigma factor RpoE |
| M. vanbaalenii PYR-1 | Mvan_1778 | - | 7e-35 | 45.66% (173) | ECF subfamily RNA polymerase sigma-24 factor |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4689|M.gilvum_PYR-GCK -------MVPVMAMKAPSRSVFVLDVIGG-AATEGTVFPTMTD----TNG
Mvan_1778|M.vanbaalenii_PYR-1 -----------MAMEAPSRSVHVLDVIGG-AATEGTVFPTMTD----ITG
TH_0665|M.thermoresistible__bu ----------------------------------------MTD----IEG
Mb3250c|M.bovis_AF2122/97 ----------------------------------------MAD----IDG
Rv3223c|M.tuberculosis_H37Rv ----------------------------------------MAD----IDG
MMAR_1334|M.marinum_M -MSTSTSLLGEERLGRFPASPASVATLSGGTSTEGTVFIKMAD----IDG
MUL_2545|M.ulcerans_Agy99 ----------------------------------------MAD----IDG
MAV_4171|M.avium_104 MVSTATSLLGEEQLAGFLASPGALSVLSGDTAAEGTGFIEMADSPDGPDG
MAB_3543c|M.abscessus_ATCC_199 --------------MACLERPMSVPIRMVGVATERTAVTSMDS----AAE
MSMEG_1747|M.smegmatis_MC2_155 -------------------------------------MFATCG-----AG
MLBr_01076|M.leprae_Br4923 -MGDGIGMEREGRWTGNTQCPLRVVPGDESPTLDGRASPEDLIITNLLSP
Mflv_4689|M.gilvum_PYR-GCK LAASPAPADAG------EAREETDAELTARFERDAIPLLDQLYGG-----
Mvan_1778|M.vanbaalenii_PYR-1 SAAEATLDGEA------PAREETDAELTARFERDAIPLLDQLYGG-----
TH_0665|M.thermoresistible__bu TTPIRS--------------EESDAELTARFERDAIPLLDQLYGG-----
Mb3250c|M.bovis_AF2122/97 VTGSAGLQP--------GPSEETDEELTARFERDAIPLLDQLYGG-----
Rv3223c|M.tuberculosis_H37Rv VTGSAGLQP--------GPSEETDEELTARFERDAIPLLDQLYGG-----
MMAR_1334|M.marinum_M VTLAEAPDP--------EPPEETDEQLTARFERDAIPLLDQLYGG-----
MUL_2545|M.ulcerans_Agy99 VTLAEAPDP--------EPPEETDEQLTACFERDAIPLLDQLYGG-----
MAV_4171|M.avium_104 VTSPEVPEAHAEPAAHEETREETDAELTARFERDAIPLLDQLYGG-----
MAB_3543c|M.abscessus_ATCC_199 LPGLVH--------------VETEAERVARFERDALPLLDQLYGA-----
MSMEG_1747|M.smegmatis_MC2_155 VTITGP------------------DALTERFVRETEPVRDFLIRN-----
MLBr_01076|M.leprae_Br4923 TIMSHPPPSRDDDWVEPFDALQGTAVFDATGDKATMPSWEELVRQHAARV
: : * : *
Mflv_4689|M.gilvum_PYR-GCK ---ALRMTRNPADAEDLLQETMVKAYSGFRSFREGTNLKAWLYRILTNTY
Mvan_1778|M.vanbaalenii_PYR-1 ---ALRMTRNPADAEDLLQETMVKAYSGFRSFREGTNLKAWLYRILTNTY
TH_0665|M.thermoresistible__bu ---ALRMTRNPADAEDLLQETMVKAYQGFRSFREGTNLKAWLYRILTNTY
Mb3250c|M.bovis_AF2122/97 ---ALRMTRNPADAEDLLQETMVKAYAGFRSFRHGTNLKAWLYRILTNTY
Rv3223c|M.tuberculosis_H37Rv ---ALRMTRNPADAEDLLQETMVKAYAGFRSFRHGTNLKAWLYRILTNTY
MMAR_1334|M.marinum_M ---ALRMTRNPADAEDLLQETMVKAYAGFRSFREGTNLKAWLYRILTNTY
MUL_2545|M.ulcerans_Agy99 ---ALRMTRNPADAEDLLQETMVKAYAGFRSFREGTNLKAWLYRILTNTY
MAV_4171|M.avium_104 ---ALRMTRNPADAEDLLQETMVKAYAGFRSFRAGTNLKAWLYRILTNTY
MAB_3543c|M.abscessus_ATCC_199 ---ALRMTRNPADAEDLVQETMVKAYAGFGTFKEGTNLKAWLYRILTNTY
MSMEG_1747|M.smegmatis_MC2_155 ---AIRLTHQRADAEDLVQETLLKAYLSFGRYREGNHLKAWLARIMSNAW
MLBr_01076|M.leprae_Br4923 YWLAYRLSGNQHDAEDLTQETFIRVFRSVQNYQPGT-FEGWLHRITTNLF
* *:: : ***** ***:::.: .. :: *. ::.** ** :* :
Mflv_4689|M.gilvum_PYR-GCK INSYRKKQRQPAEYPTEEITDWQLAANAEHTSTG-LRSAEVEALELLPDS
Mvan_1778|M.vanbaalenii_PYR-1 INSYRKKQRQPAEYPTEEITDWQLAANAEHSSTG-LRSAEVEALELLPDN
TH_0665|M.thermoresistible__bu INNYRKRQRQPAVYPTEEFTDWQLASTAEHSSTG-LRSAEVEALEALPDT
Mb3250c|M.bovis_AF2122/97 INSYRKKQRQPAEYPTEQITDWQLASNAEHSSTG-LRSAEVEALEALPDT
Rv3223c|M.tuberculosis_H37Rv INSYRKKQRQPAEYPTEQITDWQLASNAEHSSTG-LRSAEVEALEALPDT
MMAR_1334|M.marinum_M INSYRKKQRQPAEYPTDEITDWQLASNAEHSSTG-LRSAEVEALEALPDT
MUL_2545|M.ulcerans_Agy99 INSYRKKQRQPAEYPTDEITDWQLASNAEHSSTG-LRSAEVEALEALPDT
MAV_4171|M.avium_104 INSYRKKQRQPAEYPTEEITDWQLASNAEHSSTG-LRSAEVEALESLPDS
MAB_3543c|M.abscessus_ATCC_199 INIYRKKQRQPAEYPTEEITDWQLAANAEHTSTG-LRSAEIEALDGLPDD
MSMEG_1747|M.smegmatis_MC2_155 IDRHRSAQRRPAEQLSAEMADLRFSTEMPSAGRGWVDSAETQALQSMPG-
MLBr_01076|M.leprae_Br4923 LDMVRRRARIRMDALPDDYDRVPADE----------PNPEQIYHDSRLGP
:: * * . : ..* : .
Mflv_4689|M.gilvum_PYR-GCK EIKEALQALPEDFRMAVYYADVEGFPYKEIAEIMETPIGTVMSRLHRGRR
Mvan_1778|M.vanbaalenii_PYR-1 EIKEALQALPDEFRMAVYYADVEGFPYKEIAEIMDTPIGTVMSRLHRGRR
TH_0665|M.thermoresistible__bu EIKAALQELPEDFRIAVYLADVEGFPYKEIAEIMDTPIGTVMSRLHRGRR
Mb3250c|M.bovis_AF2122/97 EIKEALQALPEEFRMAVYYADVEGFPYKEIAEIMDTPIGTVMSRLHRGRR
Rv3223c|M.tuberculosis_H37Rv EIKEALQALPEEFRMAVYYADVEGFPYKEIAEIMDTPIGTVMSRLHRGRR
MMAR_1334|M.marinum_M EIKEALQALPEEFRMAVYYADVEGFPYKEIAEIMDTPIGTVMSRLHRGRR
MUL_2545|M.ulcerans_Agy99 EIKEALQALPEEFRMAVYYADVEGFPYKEIAEIMDTPIGTVMSRLHRGRR
MAV_4171|M.avium_104 EIKDALQALPEEFRMAVYYADVEGFPYKEIAEIMDTPIGTVMSRLHRGRR
MAB_3543c|M.abscessus_ATCC_199 EIKEALNKLPEEFRMAVYYADVEGFPYKEIAEIMDTPIGTVMSRLHRGRR
MSMEG_1747|M.smegmatis_MC2_155 DAGIALAMLPPELRDIVYYACVADYRNTEIAVLLGIPVGTVGSRLHRGKA
MLBr_01076|M.leprae_Br4923 DLQAALDSLPPEFRAAVVLCDIEGLSYEEIGATLGVKLGTVRSRIHRGRQ
: ** ** ::* * . : . **. : :*** **:***:
Mflv_4689|M.gilvum_PYR-GCK QLRELLAGVARDRGFIRGEQLEAPEEVTS
Mvan_1778|M.vanbaalenii_PYR-1 QLRELLAGVARDRGFIRGEQVDAPEEVTS
TH_0665|M.thermoresistible__bu QLRSLLADVARERGIIRDQQAGTPEEVSS
Mb3250c|M.bovis_AF2122/97 QLRGLLADVARDRGFARGEQ--AHEGVSS
Rv3223c|M.tuberculosis_H37Rv QLRGLLADVARDRGFARGEQ--AHEGVSS
MMAR_1334|M.marinum_M QLRTLLADVAKERGFVRGEQ--AHQEVSS
MUL_2545|M.ulcerans_Agy99 QLRTLLADVAKERGFVRGEQ--AHQEVSS
MAV_4171|M.avium_104 QLRGLLADVAKERGFNRGQQ--THEEVSS
MAB_3543c|M.abscessus_ATCC_199 QLRDLLSEVAKDRGFLRNNE--LAEGRA-
MSMEG_1747|M.smegmatis_MC2_155 LLREALSHST-DNDQAPGER-----RMAG
MLBr_01076|M.leprae_Br4923 ALRDYLLTAHPRDGATTDAT---HVKSA-
** * . . :