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STSDTAVAETVTRHHPHLVALSRDLYDHPEIAWEEVRSARRVASTLAEGGFDVTERYCELDTAFAAQIGS GDLHVALCAEYDALPGLGHACGHNLISAITAGTALALAPMVDDLGLTLSVIGTPAEEGGGGKIELLERGG FDGQHFAAMVHPGPVDVARAQPFAVSHSHIEYRGKSAHAAAYPERGVNAADAFTIAQVAIGLLRQQLPVS VRVHGMMTRGGEAPNAIAEHTEGRWYVRAETLGQLAEIERKVMRCFEAGALASGAELIVTPESKPYAEFR TDDDLLACYERRATAVGRQFVSGPDTAMARASTDMGNVSQVLPAIHPYIGIDSLPAVNHQPEFAAATVTS AAETAIAHGAIALAGTVIDAASDPHLRQRLLDKR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1679 | - | - | 100% (385) | AmiB |
| M. smegmatis MC2 155 | MSMEG_1702 | - | 7e-92 | 46.60% (382) | amidohydrolase |
| M. smegmatis MC2 155 | MSMEG_1703 | - | 5e-09 | 30.00% (160) | amidohydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3334c | amiB1 | 4e-92 | 47.64% (382) | amidase AmiB1 |
| M. gilvum PYR-GCK | Mflv_4827 | - | 7e-92 | 47.26% (383) | amidohydrolase |
| M. tuberculosis H37Rv | Rv3306c | amiB1 | 4e-92 | 47.64% (382) | amidohydrolase AmiB1 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3659c | - | 2e-93 | 48.45% (386) | putative peptidase/amidohydrolase |
| M. marinum M | MMAR_1220 | amiB1 | 2e-91 | 47.87% (376) | amidohydrolase AmiB1 |
| M. avium 104 | MAV_4282 | - | 1e-90 | 46.68% (377) | amidohydrolase |
| M. thermoresistible (build 8) | TH_1761 | - | 1e-42 | 47.00% (200) | PROBABLE AMIDOHYDROLASE AMIB1 (AMINOHYDROLASE) |
| M. ulcerans Agy99 | MUL_2672 | amiB1 | 3e-89 | 47.07% (376) | amidohydrolase AmiB1 |
| M. vanbaalenii PYR-1 | Mvan_1611 | - | 2e-95 | 48.31% (385) | amidohydrolase |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_3659c|M.abscessus_ATCC_199 MPLTTGASSTAHAETASAVVDAAATDLVALSHDIHSEPELAFQEVRSALK
TH_1761|M.thermoresistible__bu --------------------------------------------------
Mb3334c|M.bovis_AF2122/97 MPAAS------ASDRVEELVRRRGGELVELSHAIHAEPELAFAEHRSCAK
Rv3306c|M.tuberculosis_H37Rv MPAAS------ASDRVEELVRRRGGELVELSHAIHAEPELAFAEHRSCAK
MMAR_1220|M.marinum_M MPAL-------VLDTVEELVRRRAGDLVELSHAIHAEPELAFAEHRSCAK
MUL_2672|M.ulcerans_Agy99 MPAL-------VLDTVEELVRRRAGDLVELSHAIHAEPELAFAEHRSCAK
MAV_4282|M.avium_104 MPPVGSDS---PLDSVEDVVRRRGADLVELSHAIHAEPELAFAEHRSCAK
Mflv_4827|M.gilvum_PYR-GCK MSSAA------ASTSVEDAVNRRRSDLIELSHSIHAEPELAFAEHRSCAK
Mvan_1611|M.vanbaalenii_PYR-1 MPLAA------ASTCVEDAVRSRRADLVALSHAIHAEPELAFAEHRSCAK
MSMEG_1679|M.smegmatis_MC2_155 MSTSD--------TAVAETVTRHHPHLVALSRDLYDHPEIAWEEVRSARR
MAB_3659c|M.abscessus_ATCC_199 TQRLLAERGFEIVTGQGGMDTAFRATYGHGPLVIGVCAEYDALPGIGHAC
TH_1761|M.thermoresistible__bu --------------------------------------------------
Mb3334c|M.bovis_AF2122/97 AQALVAERGFEITTAAGGLDTAFRADYGSGPLVVGVCAEYDALPGIGHAC
Rv3306c|M.tuberculosis_H37Rv AQALVAERGFEITTAAGGLDTAFRADYGSGPLVVGVCAEYDALPGIGHAC
MMAR_1220|M.marinum_M TQALVAERGFEITRAAAGLDTAFRADFGDGPLVVGICAEYDALPEIGHAC
MUL_2672|M.ulcerans_Agy99 TQALVAERGFEITRAAAGLDTAFRADFGDGPLVVGICAEYNALPEIGHAC
MAV_4282|M.avium_104 AQALVAERGFEITAAAGGLDTAFRADFGSGQLTIGVCAEYDALPEIGHAC
Mflv_4827|M.gilvum_PYR-GCK TQALAAERGFEVSE-VAGLDTAFRAVYGSGPLVIGVCAEYDALPGIGHAC
Mvan_1611|M.vanbaalenii_PYR-1 TQALVAERGFEITAGVAGLDTAFRAVYGSGPLVVGVCAEYDALPEMGHAC
MSMEG_1679|M.smegmatis_MC2_155 VASTLAEGGFDVTERYCELDTAFAAQIGSGDLHVALCAEYDALPGLGHAC
MAB_3659c|M.abscessus_ATCC_199 GHNIIAASAVGTGLGLAEVADALGLTVVVIGTPAEEFGGGKALLLKAGAF
TH_1761|M.thermoresistible__bu --------------------------------------------------
Mb3334c|M.bovis_AF2122/97 GHNIIAASAVGTALALAEVADDLGLTVALLGTPAEESGGGKALMLQAGTF
Rv3306c|M.tuberculosis_H37Rv GHNIIAASAVGTALALAEVADDLGLTVALLGTPAEESGGGKALMLQAGTF
MMAR_1220|M.marinum_M GHNIIAASAVGTALALAEVADDLGLTVALLGTPAEESGGGKALMLDAGVF
MUL_2672|M.ulcerans_Agy99 GHNIIAASAVGTALALAEVADDLGLTVALLGTPAEESGGGKALMLDAGVF
MAV_4282|M.avium_104 GHNIIAASAVGTALALAEVADDLGLRVALVGTPAEEAGGGKALLLKAGVF
Mflv_4827|M.gilvum_PYR-GCK GHNIIAASAVGTALALAEVADELGLTVVLLGTPAEELGGGKALMLDAGAF
Mvan_1611|M.vanbaalenii_PYR-1 GHNIIAASAVGTALALAEVADALGLTVVLLGTPAEELGGGKALMLQAGVF
MSMEG_1679|M.smegmatis_MC2_155 GHNLISAITAGTALALAPMVDDLGLTLSVIGTPAEEGGGGKIELLERGGF
MAB_3659c|M.abscessus_ATCC_199 DDVAAAVMLHPGPIDIAGARSLALTDVMVTYHGKESHAAVAPQLGINAAD
TH_1761|M.thermoresistible__bu -------------------------------------------XGVNAAD
Mb3334c|M.bovis_AF2122/97 DDVAVAVMVHPGPTDIAGARSLALSEVTVRYRGKESHAAVAPHLGVNAAD
Rv3306c|M.tuberculosis_H37Rv DDVAVAVMVHPGPTDIAGARSLALSEVTVRYRGKESHAAVAPHLGVNAAD
MMAR_1220|M.marinum_M DDITLALMVHPGPTDIAGARSLALSEVTVRYRGKESHAAVAPHLGVNAAD
MUL_2672|M.ulcerans_Agy99 DDITLALMVHPGPTDIAGARSLALSEVTVRYRGKESHAAVAPHLGVNAAD
MAV_4282|M.avium_104 DDISAAVMLHPGPADIAAARSLALSEAIVRYRGKESHAAVAPHLGVNALD
Mflv_4827|M.gilvum_PYR-GCK DDIAAAVMLHPGPLDIAAARSLALSEVTIGYTGRESHAAVAPHLGVNAGD
Mvan_1611|M.vanbaalenii_PYR-1 DDIAATVMLHPGPVDIAAARSLALSEMTIHYTGRESHAAVAPFLGVNAGD
MSMEG_1679|M.smegmatis_MC2_155 DGQHFAAMVHPGPVDVARAQPFAVSHSHIEYRGKSAHAAAYPERGVNAAD
*:** *
MAB_3659c|M.abscessus_ATCC_199 AVTVAQVSIGLLRQHLSPGQLIHGIVTEGGEAANIIPGRAAMQYTMRAVE
TH_1761|M.thermoresistible__bu AVTVAQVAIGLLRQHLEPGQQVHGIVTDGGQATNVIPAHAGMTYTMRAPH
Mb3334c|M.bovis_AF2122/97 AVTVAQVAIGVLRQQLAPGQMVHGIVTDGGQAVNVIPGQARLQYAMRAVE
Rv3306c|M.tuberculosis_H37Rv AVTVAQVAIGVLRQQLAPGQMVHGIVTDGGQAVNVIPGQARLQYAMRAVE
MMAR_1220|M.marinum_M ALTIAQVAIGLLRQQLAPGQMTHGIVIDGGQAVNVIPGHAMMQYAMRAVE
MUL_2672|M.ulcerans_Agy99 ALTIAQVAIGLLRQQLAPGQMTHGIVIDGGQAVNVIPGHAMMQYAMRAVE
MAV_4282|M.avium_104 AVTVAQVAVGLLRQQLAPGQLVHGIVTDGGQAVNVIPGHASLQYAMRAVE
Mflv_4827|M.gilvum_PYR-GCK AVTVTQVAIGLLRQQLAPGQMVHGIVTDGGQASNVIPAHTELRYTMRATN
Mvan_1611|M.vanbaalenii_PYR-1 AVTVAQVAIGLLRQQLAPGQMVHGIVTDGGQASNVIPGHTEMRYTMRAND
MSMEG_1679|M.smegmatis_MC2_155 AFTIAQVAIGLLRQQLPVSVRVHGMMTRGGEAPNAIAEHTEGRWYVRAET
*.*::**::*:***:* . **:: **:* * *. :: : :**
MAB_3659c|M.abscessus_ATCC_199 TASLRELEEKVYACFAAGAMATGCSHELVESSPPYLELTPDPWLVAVFRE
TH_1761|M.thermoresistible__bu AAALRALERRMADCFAAGALATGCSHTVTETSPPYDELAPDPWLAEVFRT
Mb3334c|M.bovis_AF2122/97 SDSLRELQTRMFACFAAGALAAGCEYEIDEAAPAYAELKPDPWLADVCRE
Rv3306c|M.tuberculosis_H37Rv SDSLRELQTRMFACFAAGALAAGCEYEIDEAAPAYAELKPDPWLADVCRE
MMAR_1220|M.marinum_M SESLRDLEGRMFACFAAGALAAGCEYDIDAAAPAYAELKPDHWLVEVCRE
MUL_2672|M.ulcerans_Agy99 SESLRDLEGRMFACFAAGALAAGCGYDIDAAAPAYAELKPDHWLVEVCRE
MAV_4282|M.avium_104 SDSLRELEGRMYACFAAGAMAAGCEYEIDNPAPAYDELKPDAWLANIFRE
Mflv_4827|M.gilvum_PYR-GCK SESLHELESRMAGCFASGAVATGCEHVVSETAPAYAELAPDPWLAERVRA
Mvan_1611|M.vanbaalenii_PYR-1 SESLRALESRMAGCFAAGAVATGCEHVVSDTAPAYAELAPDPWLSEVFRA
MSMEG_1679|M.smegmatis_MC2_155 LGQLAEIERKVMRCFEAGALASGAELIVTPESKPYAEFRTDDDLLACYER
* :: :: ** :**:*:*. : : .* *: .* * .
MAB_3659c|M.abscessus_ATCC_199 EMESFGRTPVPAEFEATVPLGSTDMGNVTQVLPGIHPVIGIDSGGAVIHQ
TH_1761|M.thermoresistible__bu EMVRMGRAPVPAEVEATIPLGSTDMGNVTQVMPGIHPVVGIDSGGAAIHQ
Mb3334c|M.bovis_AF2122/97 EMQRLGREPLLPALEAELPLGSTDMGNVTQVLPGIHPVIGLDAGAATVHQ
Rv3306c|M.tuberculosis_H37Rv EMQRLGREPLLPALEAELPLGSTDMGNVTQVLPGIHPVIGLDAGAATVHQ
MMAR_1220|M.marinum_M EMLRLGRTPVPASVEEGLPLGSTDMGNVTQVLPGIHPVIGVDAGGATVHQ
MUL_2672|M.ulcerans_Agy99 EMLRLGRTPVPASVEEGLPLGSTDMGNVTQVLPGIRPVIGVDAGGATVHQ
MAV_4282|M.avium_104 EMCRLGRQPVAPEYEAALPMGSTDMGNVTQALPGIHPVVGVESGGAMVHQ
Mflv_4827|M.gilvum_PYR-GCK EMLRRGRTPVPAELEAEFPLGSTDMGNVTQVMPGIHPIVGIDAGGASIHQ
Mvan_1611|M.vanbaalenii_PYR-1 EMTRVGRTPVAAELEASLPLGSTDMGNVTQVMPGIHPIVGIDAGGASIHQ
MSMEG_1679|M.smegmatis_MC2_155 RATAVGRQFVSGP-DTAMARASTDMGNVSQVLPAIHPYIGIDSLPAVNHQ
. ** : : .. .*******:*.:*.*:* :*::: * **
MAB_3659c|M.abscessus_ATCC_199 PDFEKAAREPGADRAVVEGAKMLARTVIRLAEDESERSRVLDR-LARRTV
TH_1761|M.thermoresistible__bu PEFAAAAVSPSADRAVVEGAVMLARTVVRLAETPAERDRVLQRREARRTS
Mb3334c|M.bovis_AF2122/97 RAFTVASAGASADRAVVDGAIMLARTVVRLAQTPDERDRVLAAQQRRAAR
Rv3306c|M.tuberculosis_H37Rv RAFTVASAGASADRAVVDGAIMLARTVVRLAQTPDERDRVLAAQQRRAAR
MMAR_1220|M.marinum_M RAFAAAAAGHSADQAVVDGAIMLARTAVALAENPDQRDRVLAAQQRRAAS
MUL_2672|M.ulcerans_Agy99 RAFAAAAAGHSADQAVVDGAIMLARTAVALAENPDQRDRVLAAQQRRAAS
MAV_4282|M.avium_104 RAFADAAAGPSADRAVIEGAIMLARTVVALAQTPAERDRVLAAHERRRGG
Mflv_4827|M.gilvum_PYR-GCK PAFTAAAVNASADAAVVDGAIMLARTVVALAESDVERDRVLDLWRKRAS-
Mvan_1611|M.vanbaalenii_PYR-1 PEFAAAAVSASADTAVVEGAIMLARTVVALAESGVERDRVLEQWQRRAS-
MSMEG_1679|M.smegmatis_MC2_155 PEFAAATVTSAAETAIAHGAIALAGTVIDAASDPHLRQRLLDKR------
* *: .*: *: .** ** *.: *. *.*:*
MAB_3659c|M.abscessus_ATCC_199 KV-
TH_1761|M.thermoresistible__bu ---
Mb3334c|M.bovis_AF2122/97 ---
Rv3306c|M.tuberculosis_H37Rv ---
MMAR_1220|M.marinum_M ---
MUL_2672|M.ulcerans_Agy99 ---
MAV_4282|M.avium_104 AHP
Mflv_4827|M.gilvum_PYR-GCK ---
Mvan_1611|M.vanbaalenii_PYR-1 ---
MSMEG_1679|M.smegmatis_MC2_155 ---