For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. abscessus ATCC 19977 MAB_3659c (-)

annotation: putative peptidase/amidohydrolase
coordinates: 3712076 - 3713281
length: 401

PLTTGASSTAHAETASAVVDAAATDLVALSHDIHSEPELAFQEVRSALKTQRLLAERGFEIVTGQGGMDT
AFRATYGHGPLVIGVCAEYDALPGIGHACGHNIIAASAVGTGLGLAEVADALGLTVVVIGTPAEEFGGGK
ALLLKAGAFDDVAAAVMLHPGPIDIAGARSLALTDVMVTYHGKESHAAVAPQLGINAADAVTVAQVSIGL
LRQHLSPGQLIHGIVTEGGEAANIIPGRAAMQYTMRAVETASLRELEEKVYACFAAGAMATGCSHELVES
SPPYLELTPDPWLVAVFREEMESFGRTPVPAEFEATVPLGSTDMGNVTQVLPGIHPVIGIDSGGAVIHQP
DFEKAAREPGADRAVVEGAKMLARTVIRLAEDESERSRVLDRLARRTVKV*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. abscessus ATCC 19977MAB_3659c--100% (401)putative peptidase/amidohydrolase
M. abscessus ATCC 19977MAB_4738c-8e-1826.98% (341) putative amidohydrolase
M. abscessus ATCC 19977MAB_3658c-3e-1427.29% (414) putative peptidase/amidohydrolase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3334camiB11e-15169.87% (375) amidase AmiB1
M. gilvum PYR-GCKMflv_4827-1e-15067.69% (390) amidohydrolase
M. tuberculosis H37RvRv3306camiB11e-15169.87% (375) amidohydrolase AmiB1
M. leprae Br4923-----
M. marinum MMMAR_1220amiB11e-14767.19% (384) amidohydrolase AmiB1
M. avium 104MAV_4282-1e-15067.61% (389) amidohydrolase
M. smegmatis MC2 155MSMEG_1702-1e-15168.99% (387) amidohydrolase
M. thermoresistible (build 8)TH_1761-7e-8272.20% (205) PROBABLE AMIDOHYDROLASE AMIB1 (AMINOHYDROLASE)
M. ulcerans Agy99MUL_2672amiB11e-14666.67% (384) amidohydrolase AmiB1
M. vanbaalenii PYR-1Mvan_1611-1e-15368.81% (388) amidohydrolase

CLUSTAL 2.0.9 multiple sequence alignment


Mb3334c|M.bovis_AF2122/97           ---MPAAS---ASDRVEELVRRRGGELVELSHAIHAEPELAFAEHRSCAK
Rv3306c|M.tuberculosis_H37Rv        ---MPAAS---ASDRVEELVRRRGGELVELSHAIHAEPELAFAEHRSCAK
MMAR_1220|M.marinum_M               ---MPAL----VLDTVEELVRRRAGDLVELSHAIHAEPELAFAEHRSCAK
MUL_2672|M.ulcerans_Agy99           ---MPAL----VLDTVEELVRRRAGDLVELSHAIHAEPELAFAEHRSCAK
MAV_4282|M.avium_104                ---MPPVGSDSPLDSVEDVVRRRGADLVELSHAIHAEPELAFAEHRSCAK
MSMEG_1702|M.smegmatis_MC2_155      ---MSTAT---ASRSVEDAVRRRSGDLIELSHSIHAEPELAFAEHRSSAK
Mflv_4827|M.gilvum_PYR-GCK          ---MSSAA---ASTSVEDAVNRRRSDLIELSHSIHAEPELAFAEHRSCAK
Mvan_1611|M.vanbaalenii_PYR-1       ---MPLAA---ASTCVEDAVRSRRADLVALSHAIHAEPELAFAEHRSCAK
TH_1761|M.thermoresistible__bu      --------------------------------------------------
MAB_3659c|M.abscessus_ATCC_199      MPLTTGASSTAHAETASAVVDAAATDLVALSHDIHSEPELAFQEVRSALK
                                                                                      

Mb3334c|M.bovis_AF2122/97           AQALVAERGFEITTAAGGLDTAFRADYGSGPLVVGVCAEYDALPGIGHAC
Rv3306c|M.tuberculosis_H37Rv        AQALVAERGFEITTAAGGLDTAFRADYGSGPLVVGVCAEYDALPGIGHAC
MMAR_1220|M.marinum_M               TQALVAERGFEITRAAAGLDTAFRADFGDGPLVVGICAEYDALPEIGHAC
MUL_2672|M.ulcerans_Agy99           TQALVAERGFEITRAAAGLDTAFRADFGDGPLVVGICAEYNALPEIGHAC
MAV_4282|M.avium_104                AQALVAERGFEITAAAGGLDTAFRADFGSGQLTIGVCAEYDALPEIGHAC
MSMEG_1702|M.smegmatis_MC2_155      TQALVAEYGFEITAAAGGLDTAFRASYGSGSLVIGICAEYDALPEIGHAC
Mflv_4827|M.gilvum_PYR-GCK          TQALAAERGFEVSE-VAGLDTAFRAVYGSGPLVIGVCAEYDALPGIGHAC
Mvan_1611|M.vanbaalenii_PYR-1       TQALVAERGFEITAGVAGLDTAFRAVYGSGPLVVGVCAEYDALPEMGHAC
TH_1761|M.thermoresistible__bu      --------------------------------------------------
MAB_3659c|M.abscessus_ATCC_199      TQRLLAERGFEIVTGQGGMDTAFRATYGHGPLVIGVCAEYDALPGIGHAC
                                                                                      

Mb3334c|M.bovis_AF2122/97           GHNIIAASAVGTALALAEVADDLGLTVALLGTPAEESGGGKALMLQAGTF
Rv3306c|M.tuberculosis_H37Rv        GHNIIAASAVGTALALAEVADDLGLTVALLGTPAEESGGGKALMLQAGTF
MMAR_1220|M.marinum_M               GHNIIAASAVGTALALAEVADDLGLTVALLGTPAEESGGGKALMLDAGVF
MUL_2672|M.ulcerans_Agy99           GHNIIAASAVGTALALAEVADDLGLTVALLGTPAEESGGGKALMLDAGVF
MAV_4282|M.avium_104                GHNIIAASAVGTALALAEVADDLGLRVALVGTPAEEAGGGKALLLKAGVF
MSMEG_1702|M.smegmatis_MC2_155      GHNIIASSAVGTALALAEVADLLDLTVVLVGTPAEETGGGKVLLLDAGVF
Mflv_4827|M.gilvum_PYR-GCK          GHNIIAASAVGTALALAEVADELGLTVVLLGTPAEELGGGKALMLDAGAF
Mvan_1611|M.vanbaalenii_PYR-1       GHNIIAASAVGTALALAEVADALGLTVVLLGTPAEELGGGKALMLQAGVF
TH_1761|M.thermoresistible__bu      --------------------------------------------------
MAB_3659c|M.abscessus_ATCC_199      GHNIIAASAVGTGLGLAEVADALGLTVVVIGTPAEEFGGGKALLLKAGAF
                                                                                      

Mb3334c|M.bovis_AF2122/97           DDVAVAVMVHPGPTDIAGARSLALSEVTVRYRGKESHAAVAPHLGVNAAD
Rv3306c|M.tuberculosis_H37Rv        DDVAVAVMVHPGPTDIAGARSLALSEVTVRYRGKESHAAVAPHLGVNAAD
MMAR_1220|M.marinum_M               DDITLALMVHPGPTDIAGARSLALSEVTVRYRGKESHAAVAPHLGVNAAD
MUL_2672|M.ulcerans_Agy99           DDITLALMVHPGPTDIAGARSLALSEVTVRYRGKESHAAVAPHLGVNAAD
MAV_4282|M.avium_104                DDISAAVMLHPGPADIAAARSLALSEAIVRYRGKESHAAVAPHLGVNALD
MSMEG_1702|M.smegmatis_MC2_155      DDIAASVMLHPGPVDIAAARSLALTEVAVSYTGRESHAAVAPYLGVNAAD
Mflv_4827|M.gilvum_PYR-GCK          DDIAAAVMLHPGPLDIAAARSLALSEVTIGYTGRESHAAVAPHLGVNAGD
Mvan_1611|M.vanbaalenii_PYR-1       DDIAATVMLHPGPVDIAAARSLALSEMTIHYTGRESHAAVAPFLGVNAGD
TH_1761|M.thermoresistible__bu      -------------------------------------------XGVNAAD
MAB_3659c|M.abscessus_ATCC_199      DDVAAAVMLHPGPIDIAGARSLALTDVMVTYHGKESHAAVAPQLGINAAD
                                                                                *:** *

Mb3334c|M.bovis_AF2122/97           AVTVAQVAIGVLRQQLAPGQMVHGIVTDGGQAVNVIPGQARLQYAMRAVE
Rv3306c|M.tuberculosis_H37Rv        AVTVAQVAIGVLRQQLAPGQMVHGIVTDGGQAVNVIPGQARLQYAMRAVE
MMAR_1220|M.marinum_M               ALTIAQVAIGLLRQQLAPGQMTHGIVIDGGQAVNVIPGHAMMQYAMRAVE
MUL_2672|M.ulcerans_Agy99           ALTIAQVAIGLLRQQLAPGQMTHGIVIDGGQAVNVIPGHAMMQYAMRAVE
MAV_4282|M.avium_104                AVTVAQVAVGLLRQQLAPGQLVHGIVTDGGQAVNVIPGHASLQYAMRAVE
MSMEG_1702|M.smegmatis_MC2_155      AVTVAQVAIGLLRQQLAPGQMVHGIVTNGGQAANIIPGHAEMRYTMRAVD
Mflv_4827|M.gilvum_PYR-GCK          AVTVTQVAIGLLRQQLAPGQMVHGIVTDGGQASNVIPAHTELRYTMRATN
Mvan_1611|M.vanbaalenii_PYR-1       AVTVAQVAIGLLRQQLAPGQMVHGIVTDGGQASNVIPGHTEMRYTMRAND
TH_1761|M.thermoresistible__bu      AVTVAQVAIGLLRQHLEPGQQVHGIVTDGGQATNVIPAHAGMTYTMRAPH
MAB_3659c|M.abscessus_ATCC_199      AVTVAQVSIGLLRQHLSPGQLIHGIVTEGGEAANIIPGRAAMQYTMRAVE
                                    *:*::**::*:***:* ***  **** :**:* *:**.:: : *:*** .

Mb3334c|M.bovis_AF2122/97           SDSLRELQTRMFACFAAGALAAGCEYEIDEAAPAYAELKPDPWLADVCRE
Rv3306c|M.tuberculosis_H37Rv        SDSLRELQTRMFACFAAGALAAGCEYEIDEAAPAYAELKPDPWLADVCRE
MMAR_1220|M.marinum_M               SESLRDLEGRMFACFAAGALAAGCEYDIDAAAPAYAELKPDHWLVEVCRE
MUL_2672|M.ulcerans_Agy99           SESLRDLEGRMFACFAAGALAAGCGYDIDAAAPAYAELKPDHWLVEVCRE
MAV_4282|M.avium_104                SDSLRELEGRMYACFAAGAMAAGCEYEIDNPAPAYDELKPDAWLANIFRE
MSMEG_1702|M.smegmatis_MC2_155      MAGLHELENRMAGCFAAGALATGCEHEVSETAPAYAELRPDAWLSETVRA
Mflv_4827|M.gilvum_PYR-GCK          SESLHELESRMAGCFASGAVATGCEHVVSETAPAYAELAPDPWLAERVRA
Mvan_1611|M.vanbaalenii_PYR-1       SESLRALESRMAGCFAAGAVATGCEHVVSDTAPAYAELAPDPWLSEVFRA
TH_1761|M.thermoresistible__bu      AAALRALERRMADCFAAGALATGCSHTVTETSPPYDELAPDPWLAEVFRT
MAB_3659c|M.abscessus_ATCC_199      TASLRELEEKVYACFAAGAMATGCSHELVESSPPYLELTPDPWLVAVFRE
                                      .*: *: ::  ***:**:*:** : :  .:*.* ** ** **    * 

Mb3334c|M.bovis_AF2122/97           EMQRLGREPLLPALEAELPLGSTDMGNVTQVLPGIHPVIGLDAGAATVHQ
Rv3306c|M.tuberculosis_H37Rv        EMQRLGREPLLPALEAELPLGSTDMGNVTQVLPGIHPVIGLDAGAATVHQ
MMAR_1220|M.marinum_M               EMLRLGRTPVPASVEEGLPLGSTDMGNVTQVLPGIHPVIGVDAGGATVHQ
MUL_2672|M.ulcerans_Agy99           EMLRLGRTPVPASVEEGLPLGSTDMGNVTQVLPGIRPVIGVDAGGATVHQ
MAV_4282|M.avium_104                EMCRLGRQPVAPEYEAALPMGSTDMGNVTQALPGIHPVVGVESGGAMVHQ
MSMEG_1702|M.smegmatis_MC2_155      EMVRLGREPLPESVEASVPLGSTDMGNVTHLMPGIHPVIGVDSGGASLHQ
Mflv_4827|M.gilvum_PYR-GCK          EMLRRGRTPVPAELEAEFPLGSTDMGNVTQVMPGIHPIVGIDAGGASIHQ
Mvan_1611|M.vanbaalenii_PYR-1       EMTRVGRTPVAAELEASLPLGSTDMGNVTQVMPGIHPIVGIDAGGASIHQ
TH_1761|M.thermoresistible__bu      EMVRMGRAPVPAEVEATIPLGSTDMGNVTQVMPGIHPVVGIDSGGAAIHQ
MAB_3659c|M.abscessus_ATCC_199      EMESFGRTPVPAEFEATVPLGSTDMGNVTQVLPGIHPVIGIDSGGAVIHQ
                                    **   ** *:    *  .*:*********: :***:*::*:::*.* :**

Mb3334c|M.bovis_AF2122/97           RAFTVASAGASADRAVVDGAIMLARTVVRLAQTPDERDRVLAAQQRRAAR
Rv3306c|M.tuberculosis_H37Rv        RAFTVASAGASADRAVVDGAIMLARTVVRLAQTPDERDRVLAAQQRRAAR
MMAR_1220|M.marinum_M               RAFAAAAAGHSADQAVVDGAIMLARTAVALAENPDQRDRVLAAQQRRAAS
MUL_2672|M.ulcerans_Agy99           RAFAAAAAGHSADQAVVDGAIMLARTAVALAENPDQRDRVLAAQQRRAAS
MAV_4282|M.avium_104                RAFADAAAGPSADRAVIEGAIMLARTVVALAQTPAERDRVLAAHERRRGG
MSMEG_1702|M.smegmatis_MC2_155      PAFAAAAAGPSADKAVVEGAIMLARTVVQLAETPAERDRVLAAQSRRVAS
Mflv_4827|M.gilvum_PYR-GCK          PAFTAAAVNASADAAVVDGAIMLARTVVALAESDVERDRVLDLWRKRAS-
Mvan_1611|M.vanbaalenii_PYR-1       PEFAAAAVSASADTAVVEGAIMLARTVVALAESGVERDRVLEQWQRRAS-
TH_1761|M.thermoresistible__bu      PEFAAAAVSPSADRAVVEGAVMLARTVVRLAETPAERDRVLQRREARRTS
MAB_3659c|M.abscessus_ATCC_199      PDFEKAAREPGADRAVVEGAKMLARTVIRLAEDESERSRVLDRLARRTVK
                                      *  *:   .** **::** *****.: **:   :*.***     *   

Mb3334c|M.bovis_AF2122/97           ---
Rv3306c|M.tuberculosis_H37Rv        ---
MMAR_1220|M.marinum_M               ---
MUL_2672|M.ulcerans_Agy99           ---
MAV_4282|M.avium_104                AHP
MSMEG_1702|M.smegmatis_MC2_155      ---
Mflv_4827|M.gilvum_PYR-GCK          ---
Mvan_1611|M.vanbaalenii_PYR-1       ---
TH_1761|M.thermoresistible__bu      ---
MAB_3659c|M.abscessus_ATCC_199      V--