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SSAAASTSVEDAVNRRRSDLIELSHSIHAEPELAFAEHRSCAKTQALAAERGFEVSEVAGLDTAFRAVYG SGPLVIGVCAEYDALPGIGHACGHNIIAASAVGTALALAEVADELGLTVVLLGTPAEELGGGKALMLDAG AFDDIAAAVMLHPGPLDIAAARSLALSEVTIGYTGRESHAAVAPHLGVNAGDAVTVTQVAIGLLRQQLAP GQMVHGIVTDGGQASNVIPAHTELRYTMRATNSESLHELESRMAGCFASGAVATGCEHVVSETAPAYAEL APDPWLAERVRAEMLRRGRTPVPAELEAEFPLGSTDMGNVTQVMPGIHPIVGIDAGGASIHQPAFTAAAV NASADAAVVDGAIMLARTVVALAESDVERDRVLDLWRKRAS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4827 | - | - | 100% (392) | amidohydrolase |
| M. gilvum PYR-GCK | Mflv_4826 | - | 1e-14 | 27.91% (369) | amidohydrolase |
| M. gilvum PYR-GCK | Mflv_1971 | - | 1e-13 | 27.86% (280) | amidohydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3334c | amiB1 | 1e-167 | 74.81% (393) | amidase AmiB1 |
| M. tuberculosis H37Rv | Rv3306c | amiB1 | 1e-167 | 74.81% (393) | amidohydrolase AmiB1 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3659c | - | 1e-150 | 67.69% (390) | putative peptidase/amidohydrolase |
| M. marinum M | MMAR_1220 | amiB1 | 1e-164 | 74.55% (385) | amidohydrolase AmiB1 |
| M. avium 104 | MAV_4282 | - | 1e-159 | 73.37% (383) | amidohydrolase |
| M. smegmatis MC2 155 | MSMEG_1702 | - | 1e-174 | 77.86% (393) | amidohydrolase |
| M. thermoresistible (build 8) | TH_1761 | - | 1e-81 | 74.62% (197) | PROBABLE AMIDOHYDROLASE AMIB1 (AMINOHYDROLASE) |
| M. ulcerans Agy99 | MUL_2672 | amiB1 | 1e-162 | 73.77% (385) | amidohydrolase AmiB1 |
| M. vanbaalenii PYR-1 | Mvan_1611 | - | 0.0 | 86.77% (393) | amidohydrolase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4827|M.gilvum_PYR-GCK ---MSSAA---ASTSVEDAVNRRRSDLIELSHSIHAEPELAFAEHRSCAK
Mvan_1611|M.vanbaalenii_PYR-1 ---MPLAA---ASTCVEDAVRSRRADLVALSHAIHAEPELAFAEHRSCAK
Mb3334c|M.bovis_AF2122/97 ---MPAAS---ASDRVEELVRRRGGELVELSHAIHAEPELAFAEHRSCAK
Rv3306c|M.tuberculosis_H37Rv ---MPAAS---ASDRVEELVRRRGGELVELSHAIHAEPELAFAEHRSCAK
MMAR_1220|M.marinum_M ---MPAL----VLDTVEELVRRRAGDLVELSHAIHAEPELAFAEHRSCAK
MUL_2672|M.ulcerans_Agy99 ---MPAL----VLDTVEELVRRRAGDLVELSHAIHAEPELAFAEHRSCAK
MAV_4282|M.avium_104 ---MPPVGSDSPLDSVEDVVRRRGADLVELSHAIHAEPELAFAEHRSCAK
MSMEG_1702|M.smegmatis_MC2_155 ---MSTAT---ASRSVEDAVRRRSGDLIELSHSIHAEPELAFAEHRSSAK
TH_1761|M.thermoresistible__bu --------------------------------------------------
MAB_3659c|M.abscessus_ATCC_199 MPLTTGASSTAHAETASAVVDAAATDLVALSHDIHSEPELAFQEVRSALK
Mflv_4827|M.gilvum_PYR-GCK TQALAAERGFEVSE-VAGLDTAFRAVYGSGPLVIGVCAEYDALPGIGHAC
Mvan_1611|M.vanbaalenii_PYR-1 TQALVAERGFEITAGVAGLDTAFRAVYGSGPLVVGVCAEYDALPEMGHAC
Mb3334c|M.bovis_AF2122/97 AQALVAERGFEITTAAGGLDTAFRADYGSGPLVVGVCAEYDALPGIGHAC
Rv3306c|M.tuberculosis_H37Rv AQALVAERGFEITTAAGGLDTAFRADYGSGPLVVGVCAEYDALPGIGHAC
MMAR_1220|M.marinum_M TQALVAERGFEITRAAAGLDTAFRADFGDGPLVVGICAEYDALPEIGHAC
MUL_2672|M.ulcerans_Agy99 TQALVAERGFEITRAAAGLDTAFRADFGDGPLVVGICAEYNALPEIGHAC
MAV_4282|M.avium_104 AQALVAERGFEITAAAGGLDTAFRADFGSGQLTIGVCAEYDALPEIGHAC
MSMEG_1702|M.smegmatis_MC2_155 TQALVAEYGFEITAAAGGLDTAFRASYGSGSLVIGICAEYDALPEIGHAC
TH_1761|M.thermoresistible__bu --------------------------------------------------
MAB_3659c|M.abscessus_ATCC_199 TQRLLAERGFEIVTGQGGMDTAFRATYGHGPLVIGVCAEYDALPGIGHAC
Mflv_4827|M.gilvum_PYR-GCK GHNIIAASAVGTALALAEVADELGLTVVLLGTPAEELGGGKALMLDAGAF
Mvan_1611|M.vanbaalenii_PYR-1 GHNIIAASAVGTALALAEVADALGLTVVLLGTPAEELGGGKALMLQAGVF
Mb3334c|M.bovis_AF2122/97 GHNIIAASAVGTALALAEVADDLGLTVALLGTPAEESGGGKALMLQAGTF
Rv3306c|M.tuberculosis_H37Rv GHNIIAASAVGTALALAEVADDLGLTVALLGTPAEESGGGKALMLQAGTF
MMAR_1220|M.marinum_M GHNIIAASAVGTALALAEVADDLGLTVALLGTPAEESGGGKALMLDAGVF
MUL_2672|M.ulcerans_Agy99 GHNIIAASAVGTALALAEVADDLGLTVALLGTPAEESGGGKALMLDAGVF
MAV_4282|M.avium_104 GHNIIAASAVGTALALAEVADDLGLRVALVGTPAEEAGGGKALLLKAGVF
MSMEG_1702|M.smegmatis_MC2_155 GHNIIASSAVGTALALAEVADLLDLTVVLVGTPAEETGGGKVLLLDAGVF
TH_1761|M.thermoresistible__bu --------------------------------------------------
MAB_3659c|M.abscessus_ATCC_199 GHNIIAASAVGTGLGLAEVADALGLTVVVIGTPAEEFGGGKALLLKAGAF
Mflv_4827|M.gilvum_PYR-GCK DDIAAAVMLHPGPLDIAAARSLALSEVTIGYTGRESHAAVAPHLGVNAGD
Mvan_1611|M.vanbaalenii_PYR-1 DDIAATVMLHPGPVDIAAARSLALSEMTIHYTGRESHAAVAPFLGVNAGD
Mb3334c|M.bovis_AF2122/97 DDVAVAVMVHPGPTDIAGARSLALSEVTVRYRGKESHAAVAPHLGVNAAD
Rv3306c|M.tuberculosis_H37Rv DDVAVAVMVHPGPTDIAGARSLALSEVTVRYRGKESHAAVAPHLGVNAAD
MMAR_1220|M.marinum_M DDITLALMVHPGPTDIAGARSLALSEVTVRYRGKESHAAVAPHLGVNAAD
MUL_2672|M.ulcerans_Agy99 DDITLALMVHPGPTDIAGARSLALSEVTVRYRGKESHAAVAPHLGVNAAD
MAV_4282|M.avium_104 DDISAAVMLHPGPADIAAARSLALSEAIVRYRGKESHAAVAPHLGVNALD
MSMEG_1702|M.smegmatis_MC2_155 DDIAASVMLHPGPVDIAAARSLALTEVAVSYTGRESHAAVAPYLGVNAAD
TH_1761|M.thermoresistible__bu -------------------------------------------XGVNAAD
MAB_3659c|M.abscessus_ATCC_199 DDVAAAVMLHPGPIDIAGARSLALTDVMVTYHGKESHAAVAPQLGINAAD
*:** *
Mflv_4827|M.gilvum_PYR-GCK AVTVTQVAIGLLRQQLAPGQMVHGIVTDGGQASNVIPAHTELRYTMRATN
Mvan_1611|M.vanbaalenii_PYR-1 AVTVAQVAIGLLRQQLAPGQMVHGIVTDGGQASNVIPGHTEMRYTMRAND
Mb3334c|M.bovis_AF2122/97 AVTVAQVAIGVLRQQLAPGQMVHGIVTDGGQAVNVIPGQARLQYAMRAVE
Rv3306c|M.tuberculosis_H37Rv AVTVAQVAIGVLRQQLAPGQMVHGIVTDGGQAVNVIPGQARLQYAMRAVE
MMAR_1220|M.marinum_M ALTIAQVAIGLLRQQLAPGQMTHGIVIDGGQAVNVIPGHAMMQYAMRAVE
MUL_2672|M.ulcerans_Agy99 ALTIAQVAIGLLRQQLAPGQMTHGIVIDGGQAVNVIPGHAMMQYAMRAVE
MAV_4282|M.avium_104 AVTVAQVAVGLLRQQLAPGQLVHGIVTDGGQAVNVIPGHASLQYAMRAVE
MSMEG_1702|M.smegmatis_MC2_155 AVTVAQVAIGLLRQQLAPGQMVHGIVTNGGQAANIIPGHAEMRYTMRAVD
TH_1761|M.thermoresistible__bu AVTVAQVAIGLLRQHLEPGQQVHGIVTDGGQATNVIPAHAGMTYTMRAPH
MAB_3659c|M.abscessus_ATCC_199 AVTVAQVSIGLLRQHLSPGQLIHGIVTEGGEAANIIPGRAAMQYTMRAVE
*:*::**::*:***:* *** **** :**:* *:**.:: : *:*** .
Mflv_4827|M.gilvum_PYR-GCK SESLHELESRMAGCFASGAVATGCEHVVSETAPAYAELAPDPWLAERVRA
Mvan_1611|M.vanbaalenii_PYR-1 SESLRALESRMAGCFAAGAVATGCEHVVSDTAPAYAELAPDPWLSEVFRA
Mb3334c|M.bovis_AF2122/97 SDSLRELQTRMFACFAAGALAAGCEYEIDEAAPAYAELKPDPWLADVCRE
Rv3306c|M.tuberculosis_H37Rv SDSLRELQTRMFACFAAGALAAGCEYEIDEAAPAYAELKPDPWLADVCRE
MMAR_1220|M.marinum_M SESLRDLEGRMFACFAAGALAAGCEYDIDAAAPAYAELKPDHWLVEVCRE
MUL_2672|M.ulcerans_Agy99 SESLRDLEGRMFACFAAGALAAGCGYDIDAAAPAYAELKPDHWLVEVCRE
MAV_4282|M.avium_104 SDSLRELEGRMYACFAAGAMAAGCEYEIDNPAPAYDELKPDAWLANIFRE
MSMEG_1702|M.smegmatis_MC2_155 MAGLHELENRMAGCFAAGALATGCEHEVSETAPAYAELRPDAWLSETVRA
TH_1761|M.thermoresistible__bu AAALRALERRMADCFAAGALATGCSHTVTETSPPYDELAPDPWLAEVFRT
MAB_3659c|M.abscessus_ATCC_199 TASLRELEEKVYACFAAGAMATGCSHELVESSPPYLELTPDPWLVAVFRE
.*: *: :: ***:**:*:** : : .:*.* ** ** ** *
Mflv_4827|M.gilvum_PYR-GCK EMLRRGRTPVPAELEAEFPLGSTDMGNVTQVMPGIHPIVGIDAGGASIHQ
Mvan_1611|M.vanbaalenii_PYR-1 EMTRVGRTPVAAELEASLPLGSTDMGNVTQVMPGIHPIVGIDAGGASIHQ
Mb3334c|M.bovis_AF2122/97 EMQRLGREPLLPALEAELPLGSTDMGNVTQVLPGIHPVIGLDAGAATVHQ
Rv3306c|M.tuberculosis_H37Rv EMQRLGREPLLPALEAELPLGSTDMGNVTQVLPGIHPVIGLDAGAATVHQ
MMAR_1220|M.marinum_M EMLRLGRTPVPASVEEGLPLGSTDMGNVTQVLPGIHPVIGVDAGGATVHQ
MUL_2672|M.ulcerans_Agy99 EMLRLGRTPVPASVEEGLPLGSTDMGNVTQVLPGIRPVIGVDAGGATVHQ
MAV_4282|M.avium_104 EMCRLGRQPVAPEYEAALPMGSTDMGNVTQALPGIHPVVGVESGGAMVHQ
MSMEG_1702|M.smegmatis_MC2_155 EMVRLGREPLPESVEASVPLGSTDMGNVTHLMPGIHPVIGVDSGGASLHQ
TH_1761|M.thermoresistible__bu EMVRMGRAPVPAEVEATIPLGSTDMGNVTQVMPGIHPVVGIDSGGAAIHQ
MAB_3659c|M.abscessus_ATCC_199 EMESFGRTPVPAEFEATVPLGSTDMGNVTQVLPGIHPVIGIDSGGAVIHQ
** ** *: * .*:*********: :***:*::*:::*.* :**
Mflv_4827|M.gilvum_PYR-GCK PAFTAAAVNASADAAVVDGAIMLARTVVALAESDVERDRVLDLWRKRAS-
Mvan_1611|M.vanbaalenii_PYR-1 PEFAAAAVSASADTAVVEGAIMLARTVVALAESGVERDRVLEQWQRRAS-
Mb3334c|M.bovis_AF2122/97 RAFTVASAGASADRAVVDGAIMLARTVVRLAQTPDERDRVLAAQQRRAAR
Rv3306c|M.tuberculosis_H37Rv RAFTVASAGASADRAVVDGAIMLARTVVRLAQTPDERDRVLAAQQRRAAR
MMAR_1220|M.marinum_M RAFAAAAAGHSADQAVVDGAIMLARTAVALAENPDQRDRVLAAQQRRAAS
MUL_2672|M.ulcerans_Agy99 RAFAAAAAGHSADQAVVDGAIMLARTAVALAENPDQRDRVLAAQQRRAAS
MAV_4282|M.avium_104 RAFADAAAGPSADRAVIEGAIMLARTVVALAQTPAERDRVLAAHERRRGG
MSMEG_1702|M.smegmatis_MC2_155 PAFAAAAAGPSADKAVVEGAIMLARTVVQLAETPAERDRVLAAQSRRVAS
TH_1761|M.thermoresistible__bu PEFAAAAVSPSADRAVVEGAVMLARTVVRLAETPAERDRVLQRREARRTS
MAB_3659c|M.abscessus_ATCC_199 PDFEKAAREPGADRAVVEGAKMLARTVIRLAEDESERSRVLDRLARRTVK
* *: .** **::** *****.: **: :*.*** *
Mflv_4827|M.gilvum_PYR-GCK ---
Mvan_1611|M.vanbaalenii_PYR-1 ---
Mb3334c|M.bovis_AF2122/97 ---
Rv3306c|M.tuberculosis_H37Rv ---
MMAR_1220|M.marinum_M ---
MUL_2672|M.ulcerans_Agy99 ---
MAV_4282|M.avium_104 AHP
MSMEG_1702|M.smegmatis_MC2_155 ---
TH_1761|M.thermoresistible__bu ---
MAB_3659c|M.abscessus_ATCC_199 V--