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KITSGGTADDDRPVTTVSAQTNTSVTKPKTTDADSAVVVAATSTATAPAPAAPAPAEAVTVSAQTVTSAS TPSATQPATGAEAGTTLAAASTGPSTAPAPPAAPAPAVPVQTPAAAPAPAVTAPAPAVTAPPNLRELVAH LMKVLATTAIEAVDAVVQLMAELRAVLNAPSSLGQGVSNRHASSALHPSDSIVVLLKETLHRASMPGAPS PAPNRARSAHGSVDATPATPVSVMLKSTVPVLANPQRPGPFGLPAPTEEAVTALVAMSIWALLYSALPGL SGLFAAGATGVRIGYRQAKARVTLHDMKFARFVRSGPIGVVHTGSPAVAPVSIASGDGARHLKIAS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1589 | - | - | 100% (347) | hypothetical protein MSMEG_1589 |
| M. smegmatis MC2 155 | MSMEG_5700 | - | 5e-12 | 28.99% (238) | secreted protein |
| M. smegmatis MC2 155 | MSMEG_5412 | - | 3e-10 | 34.33% (134) | immunogenic protein MPT63 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3377c | PE_PGRS50a | 4e-10 | 31.79% (280) | hypothetical protein Mb3377c |
| M. gilvum PYR-GCK | Mflv_4911 | - | 3e-10 | 32.61% (138) | hypothetical protein Mflv_4911 |
| M. tuberculosis H37Rv | Rv1158c | - | 4e-10 | 35.77% (137) | hypothetical protein Rv1158c |
| M. leprae Br4923 | MLBr_01505 | - | 4e-08 | 40.21% (97) | hypothetical protein MLBr_01505 |
| M. abscessus ATCC 19977 | MAB_3723c | - | 3e-11 | 27.51% (229) | hypothetical protein MAB_3723c |
| M. marinum M | MMAR_4294 | - | 2e-12 | 48.98% (98) | hypothetical protein MMAR_4294 |
| M. avium 104 | MAV_2859 | - | 1e-10 | 38.60% (114) | ModD protein |
| M. thermoresistible (build 8) | TH_3807 | - | 2e-08 | 34.46% (148) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_1004 | - | 6e-13 | 48.96% (96) | hypothetical protein MUL_1004 |
| M. vanbaalenii PYR-1 | Mvan_0626 | - | 2e-10 | 39.84% (123) | hypothetical protein Mvan_0626 |
CLUSTAL 2.0.9 multiple sequence alignment
TH_3807|M.thermoresistible__bu --------------------------------------------------
Rv1158c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01505|M.leprae_Br4923 --------------------------------------------------
MMAR_4294|M.marinum_M --------------------------------------------------
MUL_1004|M.ulcerans_Agy99 --------------------------------------------------
Mflv_4911|M.gilvum_PYR-GCK --------------------------------------------------
MAB_3723c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_2859|M.avium_104 --------------------------------------------------
Mvan_0626|M.vanbaalenii_PYR-1 MRSSLGVSLGAANLIAVADGRPTVRRATVTLAPPSLTGFVDRVGDPVPLV
MSMEG_1589|M.smegmatis_MC2_155 --------------------------------------------------
Mb3377c|M.bovis_AF2122/97 ---------------------MVMSLMVAPELVAAAAADLTGIGQAISAA
TH_3807|M.thermoresistible__bu ---------------------------------------------MRATR
Rv1158c|M.tuberculosis_H37Rv ---------------------------------------------MPTIW
MLBr_01505|M.leprae_Br4923 ---------------------------------------------MATIW
MMAR_4294|M.marinum_M ---------------------------------------------MASTW
MUL_1004|M.ulcerans_Agy99 ---------------------------------------------MASTW
Mflv_4911|M.gilvum_PYR-GCK ------------------------------MPDFGRRDPGGGDPSLTDIN
MAB_3723c|M.abscessus_ATCC_199 -----------------------MADGRGWFPGQGGWQENEGPEDLAALR
MAV_2859|M.avium_104 -----------------------------------MDQVEATSTRRKGLW
Mvan_0626|M.vanbaalenii_PYR-1 AADGSRHYADRLAADAIETVTRLARPHRRPDVAAVAAPAHWPESAVAALR
MSMEG_1589|M.smegmatis_MC2_155 ----------------------------------MKITSGGTADDDRPVT
Mb3377c|M.bovis_AF2122/97 NAAAAGPTTQVLAAAGDEVSAAIAALFGTHAQEYQALSARVATFHEQFVR
TH_3807|M.thermoresistible__bu KLITSSVIAAGGAVAVAL--------------------------------
Rv1158c|M.tuberculosis_H37Rv TFVRAAAVLVGSSAALLT--------------------------------
MLBr_01505|M.leprae_Br4923 TYLRATAIVVGSSAALLT--------------------------------
MMAR_4294|M.marinum_M SLSKGLAAVVVTSAAAFG--------------------------------
MUL_1004|M.ulcerans_Agy99 SLSKGLAAVVVTSAAAFG--------------------------------
Mflv_4911|M.gilvum_PYR-GCK RTDQFLDALAAQQQPFVTDRDDV---------------------------
MAB_3723c|M.abscessus_ATCC_199 RTNRMIDAIAADLPVATSDSDEY---------------------------
MAV_2859|M.avium_104 TTLAITTVSGASAVAIALP-------------------------------
Mvan_0626|M.vanbaalenii_PYR-1 ARVPHLTVVPDAVAALTAVHAERGLPGRGVVVLCDFGATGTTITLVDAGD
MSMEG_1589|M.smegmatis_MC2_155 TVSAQTNTSVTKPKTTDAD-------------------------------
Mb3377c|M.bovis_AF2122/97 SLTAAGSAYATAEAANASPLQALEQQVLG---------------------
TH_3807|M.thermoresistible__bu ----------------------------TCSATAAAQPAPAPAPSP----
Rv1158c|M.tuberculosis_H37Rv ----------------------------GGIAHADPAPAPAPAP------
MLBr_01505|M.leprae_Br4923 ----------------------------GGIAHADTAPAPAPAPAP----
MMAR_4294|M.marinum_M ----------------------------LCPGAAADPAAPQPNPNPQLPG
MUL_1004|M.ulcerans_Agy99 ----------------------------LCPAAAADPAAPQPNPNPQLPG
Mflv_4911|M.gilvum_PYR-GCK ----------------ELAQLLAGWRDDIRETPMGHVVTPLQAEAALDRV
MAB_3723c|M.abscessus_ATCC_199 ----------------AVAMMLAAWREDVGREPMPAKPTLGQARNALR--
MAV_2859|M.avium_104 ----------------------------ATSHADPEVPTPVPPSTATAPP
Mvan_0626|M.vanbaalenii_PYR-1 GMTVIGHTVRSDDFSGDLVDQLVLRHVVTGLDLDPSGTSAVASLADLRVL
MSMEG_1589|M.smegmatis_MC2_155 ----------------------------SAVVVAATSTATAPAPAAPAP-
Mb3377c|M.bovis_AF2122/97 --------------AINAPTQLWLGRPLIGDGVHGAPGTGQPGGAGGLLW
:
TH_3807|M.thermoresistible__bu ------GVPFMDQLATAAANAPAILQSAAAALGGTNTMPS----------
Rv1158c|M.tuberculosis_H37Rv --------NIPQQLISSAANAPQILQNLATALGATPPLSA----------
MLBr_01505|M.leprae_Br4923 ----APALNIPQQLISSAANAPQILQNLATALGATPPVT-----------
MMAR_4294|M.marinum_M LPALAQLSPIIQQAAGNPEQATQLLMAAAQAFAHNPAAPTES--------
MUL_1004|M.ulcerans_Agy99 LPALAQLSPIIQQAAGNPEQATQLLMAAAQAFAHNPAAPTES--------
Mflv_4911|M.gilvum_PYR-GCK TRPAAPRRRFSLAVVGSAAAAVLAIGGFGAVVAGSGPGDALYGLRTMLFG
MAB_3723c|M.abscessus_ATCC_199 --DRGGRSRMLATTVGSAAAVTLLFGGFGAAVYQSHPGDALYGLRTSLFG
MAV_2859|M.avium_104 AAPAPNGQPAPNAQPAPAAPAPNGQPAPAAPAPNDPNAAPPP--------
Mvan_0626|M.vanbaalenii_PYR-1 CRGAKERLSADTATALTSAHTAVRLTRAELDDVIAHPLDLFVAALIDTLQ
MSMEG_1589|M.smegmatis_MC2_155 ----AEAVTVSAQTVTSASTPSATQPATGAEAGTTLAAASTG--------
Mb3377c|M.bovis_AF2122/97 GNGGNGGSGAAGQVGGPGGAAGLFGNGGSGGSGGAGAAGGVGGSGGWLNG
TH_3807|M.thermoresistible__bu --------------------------------------------------
Rv1158c|M.tuberculosis_H37Rv ------------------------PKVAEPAPAAPGITATFPGLTPAAPA
MLBr_01505|M.leprae_Br4923 -------------------------------PSAPGIS------------
MMAR_4294|M.marinum_M -------------RNVASSVNQFVQEPVNPAPGSPPLGVPAPAAAPVEVA
MUL_1004|M.ulcerans_Agy99 -------------RNVASSVNQFVQEPVNPAPGSPPLGVPAPAAAPVEVA
Mflv_4911|M.gilvum_PYR-GCK EQVQ-------MRDDAVILAAQTEMQQVQQLIEQGDWQQAQAKLEAVTTT
MAB_3723c|M.abscessus_ATCC_199 APPA-------VRTDPVVLSAQTELAQVEKLISQGDWEEAQQQLGVAAAR
MAV_2859|M.avium_104 -----------------------AGAPPNGAPPAPPNGAPPPPVDPNAPP
Mvan_0626|M.vanbaalenii_PYR-1 RNGV-------PQAQLAAVATVGGGAAIPLVAQRLSETLRIPVVAPADPQ
MSMEG_1589|M.smegmatis_MC2_155 ---------------------------PSTAPAPPAAPAP----------
Mb3377c|M.bovis_AF2122/97 NGGAGGAGGTGANGGAGGNAWLFGAGGSGGAGTNGGVGGSGGFVYGNGGA
TH_3807|M.thermoresistible__bu ---------------------------APVVAPPPAATAQI---------
Rv1158c|M.tuberculosis_H37Rv AAAAPALTPSIPGVNAP------IPGITPAAPALPVTAPAA---------
MLBr_01505|M.leprae_Br4923 -----------------------FPGLTPAAATVPTSSAAT---------
MMAR_4294|M.marinum_M PPASAPVPHVPAPGAEPGTLAHLPAGIDPAHAAGPAPVAAP---------
MUL_1004|M.ulcerans_Agy99 PPASAPVPHVPAPGAEPGTLAHLPAGIDPAHAAGPAPVAAP---------
Mflv_4911|M.gilvum_PYR-GCK VATVDDVAQKEELIAQWQELTVKVEAQDPVATVPPGAPLPT---------
MAB_3723c|M.abscessus_ATCC_199 VNEVGDAQQKAELASRVQQAEVRIDAKDPQATVPPEMVTETPRI------
MAV_2859|M.avium_104 PPPADPNAGRIPNAVGGFSYVLPAGWVESDASHLDYGSALLS--------
Mvan_0626|M.vanbaalenii_PYR-1 AAAAAGAELLALRVAEVEARTTMVPAPTVAAAAVPLAWSAAAEDPALVEF
MSMEG_1589|M.smegmatis_MC2_155 ----------------------AVPVQTPAAAPAPAVTAPAP--------
Mb3377c|M.bovis_AF2122/97 GGIGGIGGIGGNGGDAGLFGNGGAGGPGPRACRVPPASTAATAATAATAE
TH_3807|M.thermoresistible__bu ----------------------TVPQPALPATVAPATAPIIKQPGTVTPT
Rv1158c|M.tuberculosis_H37Rv ----------------------APTIPG-VNAPIPGITAPAPAAAAVPAS
MLBr_01505|M.leprae_Br4923 ----------------------LPSLPG-IMA--PAISN-TPTTPGLPAS
MMAR_4294|M.marinum_M ----------------------AGAPPASAPAPAAAAPASAPGTAPAPAA
MUL_1004|M.ulcerans_Agy99 ----------------------AGAPPASAPAPAAAAPASAPGTAPAPAA
Mflv_4911|M.gilvum_PYR-GCK ---------------------FPELPAAVLDQATTSSETTAGTTSDTTAP
MAB_3723c|M.abscessus_ATCC_199 --------------------MLSPPSIAPITSTTTTSTTSTTSASTTTSD
MAV_2859|M.avium_104 ---------------------KVTGPPPMPDQPPPVANDTRIVMGRLDQK
Mvan_0626|M.vanbaalenii_PYR-1 ASYDTDYARPEVHFDRADDAFTDPAPWPWYRRPGVVFAGAATLAATALTA
MSMEG_1589|M.smegmatis_MC2_155 ---------------------AVTAPPNLRELVAHLMKVLATTAIEAVDA
Mb3377c|M.bovis_AF2122/97 P--------------------AATAGAAGYWLATAGPAGPAASAATVVRA
TH_3807|M.thermoresistible__bu APGVPLPTAEATLPNVAGTPVPQQVSLPAD--------VSALLPAAGSQL
Rv1158c|M.tuberculosis_H37Rv VPGVPSAKVDLPQLPYLPLQVPQQLSLPAD---------LPALASGVIPA
MLBr_01505|M.leprae_Br4923 TPGFPQARVDMPAMPFLPVSVPPQISLPGD---------LQALAS-----
MMAR_4294|M.marinum_M APGPAPAAPAPAPAAAAPAPAPAPAAPPAAPVAA----PAPVPAPAPAAA
MUL_1004|M.ulcerans_Agy99 APGPAPAAPAPAPAAAAPAPAPAPAAPPAAPVAAPVAAPAPVPAPAPAAA
Mflv_4911|M.gilvum_PYR-GCK SSETTAPSSETTGPSSETTTAPSETTGPAPTTTAP---TSAPTTTAPAPS
MAB_3723c|M.abscessus_ATCC_199 STSASTSTTETSGSASPSTSSSTSTSATASTSVTS---VPTSTPTTVTIT
MAV_2859|M.avium_104 LYASAEANNAKAAVRLGSDMGEFFMPYPGTRIN------QDSTPLNGANG
Mvan_0626|M.vanbaalenii_PYR-1 FVMTSQAVEAGTTPTGSPGIATPVAVAPLDAAVEAPATPAPVAPAVPFPA
MSMEG_1589|M.smegmatis_MC2_155 VVQLMAELRAVLNAPSSLGQGVSNRHASSALHPSD--SIVVLLKETLHRA
Mb3377c|M.bovis_AF2122/97 ALAIRVSPSTTVPAVTAVTAATPAWAGPVGPAACWRVRTVPPAPPPPAAA
.
TH_3807|M.thermoresistible__bu ANLMPAVPNEPGAPAPATPPMLPSGLFPTSALP-----------------
Rv1158c|M.tuberculosis_H37Rv APIAPTPPAPGAPALPPGPPSLLAALP-----------------------
MLBr_01505|M.leprae_Br4923 --------SASAAAAPVAAPTLLSALP-----------------------
MMAR_4294|M.marinum_M PAPEAAAPAPAPAPAPAAAPGFGPDAPPTQDFMYPSIGTNCLADGSNIIA
MUL_1004|M.ulcerans_Agy99 PAPEAAAPAPAPAPAPAAAPGFGPDAPPTQDFMYPSIGTNCLADGSNIIA
Mflv_4911|M.gilvum_PYR-GCK TTPTTSVGQTRSSAAPSTPPSSAPTSTTVVLQSTT-TSAAAPTTSAAPTT
MAB_3723c|M.abscessus_ATCC_199 TTPPSSAATITSTPASATETTTAPSVSTAPTTSVPGVTASTTVPPTASIV
MAV_2859|M.avium_104 STGSASYYEVKFSDASKPNGQIWTGVIGSANGGNAQRWFVVWLGTSNDPV
Mvan_0626|M.vanbaalenii_PYR-1 TETVVAAPVPGPAAAAPGPVQQRTVTKQAAPRPAPAPAAAPVAAPAPAPP
MSMEG_1589|M.smegmatis_MC2_155 SMPGAPSPAPNRARSAHGSVDATPATPVSVMLKSTVPVLANPQRPGPFGL
Mb3377c|M.bovis_AF2122/97 TAAMAASAPPPTHPYKPAGPAVMAVMAGWSATAAPAAPAVPVMRVPPALP
.
TH_3807|M.thermoresistible__bu --------------------------------------------------
Rv1158c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01505|M.leprae_Br4923 --------------------------------------------------
MMAR_4294|M.marinum_M TALSVAGPATIPTPGPGPGQTAYVFTAVGTPGPAEVQRLPLNVTWVNLTT
MUL_1004|M.ulcerans_Agy99 TALSVAGPATIPTPGPGPGQTAYVFTAVGTPGPAEVQRLPLNVTWVNLTT
Mflv_4911|M.gilvum_PYR-GCK AAPTTAAPTTAVPTTPSAVET----------TPAVEEETP----------
MAB_3723c|M.abscessus_ATCC_199 TVPTTPEGVTIVTTRPGVVNTPVITAPTTIEAPVPITRTPDNPAPAYQAP
MAV_2859|M.avium_104 DKVAAKALAESIQAWTPPPAPPAAPGGPGAPAPGAPGAPAPGAPAAPGAP
Mvan_0626|M.vanbaalenii_PYR-1 AAAPAPAPAPAQPQIPWPVFTFAPPTPEPSQEPAPSPTQQPQTSPEPSPN
MSMEG_1589|M.smegmatis_MC2_155 PAPTEEAVTALVAMSIWALLYSALPGLSGLFAAGATGVRIGYRQAKARVT
Mb3377c|M.bovis_AF2122/97 VPPYNRRAVTAPMAAPGATAVMAEMAAPSTATAASAARAVPAVAAAPAET
TH_3807|M.thermoresistible__bu --------------------------------------------------
Rv1158c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01505|M.leprae_Br4923 --------------------------------------------------
MMAR_4294|M.marinum_M GKSGSVTLKPRSDINPEGPTTLTGIADTGSGSIMSTIFGQVTTKERQCQF
MUL_1004|M.ulcerans_Agy99 GKSGSVTLKPRSDINPEGPTTLTGIADTGSGSIMSTIFGQVTTKERQCQF
Mflv_4911|M.gilvum_PYR-GCK -------------------------PSPVAPVTTTTPVLPLPGE------
MAB_3723c|M.abscessus_ATCC_199 VNSPGSGNLHGYPGSGGNAGSGSDGPSRHMPAMTSVPVAPANPGSGSANQ
MAV_2859|M.avium_104 APAAPAPAAPGAPAAPGAPAPAPGQAPAVEVSPTPTPTPQQTLSA-----
Mvan_0626|M.vanbaalenii_PYR-1 PEPSPTPEPSPTPTPEPSPTPEPSPTPTQEPQPQPDPAPQASSSPQEPSE
MSMEG_1589|M.smegmatis_MC2_155 LHDMKFARFVRSGPIGVVHTGSPAVAPVSIASGDGARHLKIAS-------
Mb3377c|M.bovis_AF2122/97 DSTPPPWVRPVPMAVWAATAARAVTAVVAAPAAPRSPAPPARPGTAAPAV
TH_3807|M.thermoresistible__bu ----------------
Rv1158c|M.tuberculosis_H37Rv ----------------
MLBr_01505|M.leprae_Br4923 ----------------
MMAR_4294|M.marinum_M MPTIGSTVVP------
MUL_1004|M.ulcerans_Agy99 MPTIGSTVVP------
Mflv_4911|M.gilvum_PYR-GCK ----------------
MAB_3723c|M.abscessus_ATCC_199 GSGSGSHTDE------
MAV_2859|M.avium_104 ----------------
Mvan_0626|M.vanbaalenii_PYR-1 EPAPVTECVPAPDTVC
MSMEG_1589|M.smegmatis_MC2_155 ----------------
Mb3377c|M.bovis_AF2122/97 TAARPVMAEPVPPVM-