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SRHHRRNHLRLSRIAAVACVAWVAALFCGPPSAIAVPEDVAGLLDIGGGRAIFLECRGSGSPTVVLMAGK GNGADDWLQVLAPGDPEQDAPGDNLPFGRGDLIHSSEAVLPAIARFTRVCAYDRPDVRMGGSDISTPRAQ PHSVDLDVDDLHALLTALGEPAPYVLVAHSYSGLIADLYARMHPETVGALVMVDAVSEQMADVVNPAALA NWDASNATTSDQVREGVLLIDAFGRIAAAPGLPAVPAVVLSADKPWRTDLLPESARQGEQVTFADWLVAQ DRLAAAIGAGHITETHSGHDIYLYSPALVVEAIRDVVAQVTRVHG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1587 | - | - | 100% (326) | alpha/beta hydrolase fold |
| M. smegmatis MC2 155 | MSMEG_3842 | - | 8e-05 | 40.30% (67) | putative esterase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3228 | lipV | 1e-05 | 35.14% (74) | lipase LipV |
| M. gilvum PYR-GCK | Mflv_1435 | - | 1e-06 | 31.06% (161) | alpha/beta hydrolase fold |
| M. tuberculosis H37Rv | Rv3203 | lipV | 1e-05 | 35.14% (74) | lipase LipV |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1510 | - | 1e-13 | 24.43% (307) | Alpha/beta hydrolase fold precursor |
| M. marinum M | MMAR_1355 | lipV | 4e-05 | 35.14% (74) | lipase LipV |
| M. avium 104 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_0592 | - | 1e-06 | 31.08% (148) | POSSIBLE HYDROLASE |
| M. ulcerans Agy99 | MUL_2524 | lipV | 2e-05 | 35.14% (74) | lipase LipV |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1355|M.marinum_M -----------------------------------------------MST
MUL_2524|M.ulcerans_Agy99 -----------------------------------------------MST
Mb3228|M.bovis_AF2122/97 --------------------------------------------------
Rv3203|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_1435|M.gilvum_PYR-GCK -----------------------------------------------MRT
TH_0592|M.thermoresistible__bu -------------------------------------------MMSAVTG
MSMEG_1587|M.smegmatis_MC2_155 MSRHHRRNHLRLSRIAAVACVAWVAALFCGPPSAIAVPEDVAGLLDIGGG
MAB_1510|M.abscessus_ATCC_1997 --------------------------------------------MTTADG
MMAR_1355|M.marinum_M DLHVHRYGPEEPVRVLTIHGVTEHGQSWEYLAG-----------------
MUL_2524|M.ulcerans_Agy99 DLHVHRYGPEEPVRVLTIHGVTEHGQSWEYLAG-----------------
Mb3228|M.bovis_AF2122/97 --------------------------------------------------
Rv3203|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_1435|M.gilvum_PYR-GCK DLLTARGGA--GRPVVLVHGLMGRGTTWPRQLP-----------------
TH_0592|M.thermoresistible__bu SLLTACGGASGGPPLVLVHGLMGRGSTWSRQVP-----------------
MSMEG_1587|M.smegmatis_MC2_155 RAIFLECRGSGSPTVVLMAGKGNGADDWLQVLAPGDPEQDAPGDNLPFGR
MAB_1510|M.abscessus_ATCC_1997 RALHYQVAGSGEPTVVFESGMGFSRTAWGLVQP-----------------
MMAR_1355|M.marinum_M ------------YLPEVS-IAAPDLL--GHGRSSWAAP--WSIDAN--VS
MUL_2524|M.ulcerans_Agy99 ------------YLPEVN-IAAPDLL--GHGRSSWAAP--WSIDAN--VS
Mb3228|M.bovis_AF2122/97 -------------MPEIP-IAAPDLL--GHGRSPWAAP--WTIDAN--VS
Rv3203|M.tuberculosis_H37Rv -------------MPEIP-IAAPDLL--GHGRSPWAAP--WTIDAN--VS
Mflv_1435|M.gilvum_PYR-GCK ------------WLIRHGRVYTYDAP--WHRGREVDDP--HPICTERFVA
TH_0592|M.thermoresistible__bu ------------WLARFGPVHTYDAP--WHRGRDVLDP--HPISTERFVD
MSMEG_1587|M.smegmatis_MC2_155 GDLIHSSEAVLPAIARFTRVCAYDRPDVRMGGSDISTPRAQPHSVDLDVD
MAB_1510|M.abscessus_ATCC_1997 ------------LVARRLRSVVYDRAN---LGRSDDDP--APRTLERITG
: . . * * . : .
MMAR_1355|M.marinum_M ALAALLKDQAD-GPVVVVGHSFGGAVALQLAAAHPDLVAALILLDPAIGL
MUL_2524|M.ulcerans_Agy99 ALAALLKDQAD-GPVVVVGHSFGGAVALQLAAAHPDLVAALILLDPAIGL
Mb3228|M.bovis_AF2122/97 ALAALLDNQGD-GPVVVVGHSFGGAVAMHLAAARPDQVAALVLLDPAVAL
Rv3203|M.tuberculosis_H37Rv ALAALLDNQGD-GPVVVVGHSFGGAVAMHLAAARPDQVAALVLLDPAVAL
Mflv_1435|M.gilvum_PYR-GCK DLGEAVESLG--EPAILVGHSMGGLHSWCLAAERPELVTALVVEDMAPDF
TH_0592|M.thermoresistible__bu DLAAAVGELG--GPAILIGHSMGGLHSWCLAAARPDLVSAVVVEDMAPDF
MSMEG_1587|M.smegmatis_MC2_155 DLHALLTALGEPAPYVLVAHSYSGLIADLYARMHPETVGALVMVDAVSEQ
MAB_1510|M.abscessus_ATCC_1997 DLDALLTALGS-GPYILVGHSYGGTIALAATATEPSRIAGVVLVDHSDEN
* : . * :::.** .* : : .*. : .::: *
MMAR_1355|M.marinum_M NGSRVREVVDAMVAFPDYTDPAEARM------ERAYGAWADVDPAVLDAE
MUL_2524|M.ulcerans_Agy99 DGSRVREVVDAMVAFPDYTDPAEARM------ERAYGAWADVDPAVLDAE
Mb3228|M.bovis_AF2122/97 DGSRVREVVDAMLASPDYLDPAEARA------EKATGAWADVDPPVLDAE
Rv3203|M.tuberculosis_H37Rv DGSRVREVVDAMLASPDYLDPAEARA------EKATGAWADVDPPVLDAE
Mflv_1435|M.gilvum_PYR-GCK RGRTTGPWEPWVHALPVEFTSADQ----------VYAEFGPVAGQYFLEA
TH_0592|M.thermoresistible__bu RGRTTGPWEPWLHALPVEFHSEQQ----------VYDEFGPIAGRYFLEA
MSMEG_1587|M.smegmatis_MC2_155 MADVVNPAALANWDASNATTSDQVR-----------------EGVLLIDA
MAB_1510|M.abscessus_ATCC_1997 LEAYYRPASPGMRLLGLAHRAALDILGRVGLLPHVVRRMMPRMPRDVLDD
. .
MMAR_1355|M.marinum_M LDEHLITLPNGRYSWRISLPAMVCYWSELARDAALPPPGIATTLVRAVRA
MUL_2524|M.ulcerans_Agy99 LDEHLITLPNGRYSWRISLPAMVCYWSELARDAALPPPGIATTLVRAVRA
Mb3228|M.bovis_AF2122/97 LDEHLVALPNGRYGWRISLPAMVCYWSELARDIVLPPVGTATTLVRAVRA
Rv3203|M.tuberculosis_H37Rv LDEHLVALPNGRYGWRISLPAMVCYWSELARDIVLPPVGTATTLVRAVRA
Mflv_1435|M.gilvum_PYR-GCK FDRTATGWR--LHGHPARWIEIAAEWGTRDYWSQWEAVTAPTLLIEAG--
TH_0592|M.thermoresistible__bu FDRTDTGWR--LHGQPRFWIEIAAEWGVREYWEQWRSVRVPALLIEAG--
MSMEG_1587|M.smegmatis_MC2_155 FGRIAAAPG---------LPAVPAVVLSADKPWRTDLLPESARQGEQVTF
MAB_1510|M.abscessus_ATCC_1997 MVSEDLTPRARRAANEEDRRFVAGMTELRSNPPALDGVPVTVISGARAEL
: : ..
MMAR_1355|M.marinum_M DPQYVSDEL--IAALRERLGADFALREFECGHMVPQAKPTEVATLIREQL
MUL_2524|M.ulcerans_Agy99 DPQYVSDEL--IAALRERLGADFALREFECGHMVPQAKPTEVATLIREQL
Mb3228|M.bovis_AF2122/97 SPAYVSDQL--LAALDKRLGADFELLDFDCGHMVPQAKPTEVAAVIRSRL
Rv3203|M.tuberculosis_H37Rv SPAYVSDQL--LAALDKRLGADFELLDFDCGHMVPQAKPTEVAAVIRSRL
Mflv_1435|M.gilvum_PYR-GCK -NSVTPPGQ--MRAMAQRSRGAEYLHVPGAGHLVHDDAPGKYRDAVEAFL
TH_0592|M.thermoresistible__bu -DSVTPPGQ--MRRMAECGHCARHVAVPGAGHLIHDDAPEAYRAAVEAFL
MSMEG_1587|M.smegmatis_MC2_155 ADWLVAQDR--LAAAIGAG----HITETHSGHDIYLYSPALVVEAIRDVV
MAB_1510|M.abscessus_ATCC_1997 LNEETRSELNAAHQMTARRLGARHVVARKSGHQVVLTEPRLIADEVFRIA
. : .** : * :
MMAR_1355|M.marinum_M KTP------
MUL_2524|M.ulcerans_Agy99 KTP------
Mb3228|M.bovis_AF2122/97 GPR------
Rv3203|M.tuberculosis_H37Rv GPR------
Mflv_1435|M.gilvum_PYR-GCK SSFA-----
TH_0592|M.thermoresistible__bu AEFAECAGR
MSMEG_1587|M.smegmatis_MC2_155 AQVTRVHG-
MAB_1510|M.abscessus_ATCC_1997 GA-------