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MEFTRVARSGQVPEGIVRRFFAGEYEFAVARLNGKAYATSNYCTHLDCMLSSGKLVDDGIGCSCHGSAFD LETGEPICPPATVAIKTYPVEERDGEIFVGVEPGEMPVGPRRRRKGA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1462 | - | - | 100% (117) | ferredoxin |
| M. smegmatis MC2 155 | MSMEG_5593 | - | 1e-12 | 39.81% (103) | pyruvate dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_5594 | - | 6e-08 | 33.77% (77) | ferredoxin-dependent glutamate synthase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2218 | qcrA | 4e-05 | 35.44% (79) | Rieske iron-sulfur protein QcrA |
| M. gilvum PYR-GCK | Mflv_3012 | - | 2e-09 | 36.84% (95) | Rieske (2Fe-2S) domain-containing protein |
| M. tuberculosis H37Rv | Rv2195 | qcrA | 4e-05 | 35.44% (79) | Rieske iron-sulfur protein QcrA |
| M. leprae Br4923 | MLBr_00880 | qcrA | 1e-05 | 35.44% (79) | putative Rieske iron-sulphur reductase component |
| M. abscessus ATCC 19977 | MAB_4369c | - | 4e-10 | 37.04% (108) | putative ferredoxin subunit of phenylpropionate dioxygenase |
| M. marinum M | MMAR_4726 | - | 9e-06 | 29.46% (112) | hypothetical protein MMAR_4726 |
| M. avium 104 | MAV_4414 | - | 2e-09 | 36.27% (102) | Rieske (2Fe-2S) domain-containing protein |
| M. thermoresistible (build 8) | TH_4003 | - | 3e-08 | 32.61% (92) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_2161 | - | 9e-05 | 29.13% (103) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_1329 | - | 2e-56 | 86.96% (115) | Rieske (2Fe-2S) domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_1462|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1329|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3012|M.gilvum_PYR-GCK --------------------------------------------------
MAB_4369c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4003|M.thermoresistible__bu --------------------------------------------------
Mb2218|M.bovis_AF2122/97 MSRADDDAVGVPPTCGGRSDEEERRIVPGPNPQDGAKDGAKATAVPREPD
Rv2195|M.tuberculosis_H37Rv MSRADDDAVGVPPTCGGRSDEEERRIVPGPNPQDGAKDGAKATAVPREPD
MLBr_00880|M.leprae_Br4923 MS---------------------------LNPKDGAG-------ASRELD
MMAR_4726|M.marinum_M --------------------------------------------------
MUL_2161|M.ulcerans_Agy99 --------------------------------------------------
MAV_4414|M.avium_104 --------------------------------------------------
MSMEG_1462|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1329|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3012|M.gilvum_PYR-GCK --------------------------------------------------
MAB_4369c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4003|M.thermoresistible__bu --------------------------------------------------
Mb2218|M.bovis_AF2122/97 EAALAAMSNQELLALGGKLDGVRIAYKEPRWPVEGTKAEKRAERSVAVWL
Rv2195|M.tuberculosis_H37Rv EAALAAMSNQELLALGGKLDGVRIAYKEPRWPVEGTKAEKRAERSVAVWL
MLBr_00880|M.leprae_Br4923 ETTQGTMSREELVALGGRLDGVNTVYKEQRWPIEGTKAEKRTERMVTFWL
MMAR_4726|M.marinum_M --------------------------------------------------
MUL_2161|M.ulcerans_Agy99 --------------------------------------------------
MAV_4414|M.avium_104 --------------------------------------------------
MSMEG_1462|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1329|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3012|M.gilvum_PYR-GCK --------------------------------------------------
MAB_4369c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4003|M.thermoresistible__bu --------------------------------------------------
Mb2218|M.bovis_AF2122/97 LLGGVFGLALLLIFLFWPWEFKAADGESDFIYSLTTPLYGLTFGLSILSI
Rv2195|M.tuberculosis_H37Rv LLGGVFGLALLLIFLFWPWEFKAADGESDFIYSLTTPLYGLTFGLSILSI
MLBr_00880|M.leprae_Br4923 LLGGVLGLTLLLIFLFWPWEYKPKEASGSFLYTIATPLYGLTFGLSILAI
MMAR_4726|M.marinum_M --------------------------------------------------
MUL_2161|M.ulcerans_Agy99 --------------------------------------------------
MAV_4414|M.avium_104 --------------------------------------------------
MSMEG_1462|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1329|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3012|M.gilvum_PYR-GCK --------------------------------------------------
MAB_4369c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4003|M.thermoresistible__bu --------------------------------------------------
Mb2218|M.bovis_AF2122/97 AIGAVLYQKRFIPEEISIQERHDGASREIDRKTVVANLTDAFEGSTIRRR
Rv2195|M.tuberculosis_H37Rv AIGAVLYQKRFIPEEISIQERHDGASREIDRKTVVANLTDAFEGSTIRRR
MLBr_00880|M.leprae_Br4923 AIGAVQFQKRFIPEEISIQERHDGASPEIDRKTVVANLTDALESSTIRRR
MMAR_4726|M.marinum_M --------------------------------------------------
MUL_2161|M.ulcerans_Agy99 --------------------------------------------------
MAV_4414|M.avium_104 ----------MNARGLRRYVDDLLRGRRPRPFLPDDFEAAQLRTAIELRA
MSMEG_1462|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1329|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3012|M.gilvum_PYR-GCK --------------------------------------------------
MAB_4369c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4003|M.thermoresistible__bu --------------------------------------------------
Mb2218|M.bovis_AF2122/97 KLIGLSFGVGMGAFGLGTLVAFAGGLIKNPWKPVVPTAEGKKAVLWTSGW
Rv2195|M.tuberculosis_H37Rv KLIGLSFGVGMGAFGLGTLVAFAGGLIKNPWKPVVPTAEGKKAVLWTSGW
MLBr_00880|M.leprae_Br4923 KLIGLSLGVGLGAFGLSTLVTFIGGFIKNPWKPVVPTANGMKAMLWTSGW
MMAR_4726|M.marinum_M --------------------------------------------------
MUL_2161|M.ulcerans_Agy99 --------------------------------------------------
MAV_4414|M.avium_104 ARPDSEVADAPRPEFLADLHRRLAEQMSGAPTRPRPGRGSTRRQVIVGTS
MSMEG_1462|M.smegmatis_MC2_155 --------------------------------------MEFTRVARSGQV
Mvan_1329|M.vanbaalenii_PYR-1 --------------------------------------MEFVRVARSGQV
Mflv_3012|M.gilvum_PYR-GCK --------------------------------------------MKSEEI
MAB_4369c|M.abscessus_ATCC_199 ------------------------------MSSG-------IRVAALEDI
TH_4003|M.thermoresistible__bu ------------------------------MSGEHTDTLRWVRAACLDDV
Mb2218|M.bovis_AF2122/97 TPRYQGETIYLARATGTEDGPPFIKMRPEDIDAGGMETVFPWRESDGDGT
Rv2195|M.tuberculosis_H37Rv TPRYQGETIYLARATGTEDGPPFIKMRPEDMDAGGMETVFPWRESDGDGT
MLBr_00880|M.leprae_Br4923 TPRYHGETIYLARATGSHSGAPFIRMRPEDVDAGGMETVFPWRESDGDGT
MMAR_4726|M.marinum_M --------------------------MGEKTTRPRLAQGREHIVATVDEI
MUL_2161|M.ulcerans_Agy99 ----------------------------MAKPPLSTKPTGWFQVAWSDEI
MAV_4414|M.avium_104 AAATAAVAAVSIDRTVIAGQSGPDRAPQIASGTLAPNQGSWQRVAASSEV
MSMEG_1462|M.smegmatis_MC2_155 PEGI----VRRFFAGEYEFAVARL------------------NGKAYATS
Mvan_1329|M.vanbaalenii_PYR-1 PEGI----VRRFYAGEHEFAVARL------------------KGKAYATS
Mflv_3012|M.gilvum_PYR-GCK PVGE----GRTLAIDGAQVAVFRLR-----------------DGSLRAVD
MAB_4369c|M.abscessus_ATCC_199 PEGEGIVVAKAIAGTADNVALLRDA-----------------DGSVWALD
TH_4003|M.thermoresistible__bu PGDE----PLGLVVDGIEIALFND------------------DGRIFALA
Mb2218|M.bovis_AF2122/97 TVESHHKLQEIAMGIRNPVMLIRIKPSDLGRVVKRKGQESFNFGEFFAFT
Rv2195|M.tuberculosis_H37Rv TVESHHKLQEIAMGIRNPVMLIRIKPSDLGRVVKRKGQESFNFGEFFAFT
MLBr_00880|M.leprae_Br4923 TMESHEKLITIKMGIRNPVMLIRIRPSDMPRVVKRRGQENFNFGEFFAFT
MMAR_4726|M.marinum_M PPGT----HKLVPIGRHGVGVYNVN------------------GTFYAIA
MUL_2161|M.ulcerans_Agy99 GVGD----VRTMKYFDQELIAWRAE-----------------SGQLTVMN
MAV_4414|M.avium_104 PDGV----LRAFDLGAVSGFVRRVD------------------GKVQAIS
. * .
MSMEG_1462|M.smegmatis_MC2_155 NYCTHLDCMLSSGKLVD------------------DGIGCSCHGSAFD-L
Mvan_1329|M.vanbaalenii_PYR-1 NYCTHLDCLLSSGKLRD------------------DGIGCSCHGSAFD-L
Mflv_3012|M.gilvum_PYR-GCK AVCPHRGGPLADGLADD------------------CVIVCPLHGHTFD-L
MAB_4369c|M.abscessus_ATCC_199 DTCTHADASLAEGWVED------------------GYVECPLHSSKFC-L
TH_4003|M.thermoresistible__bu DRCTHGDARLSDGYIED------------------GCIECPLHQALFD-L
Mb2218|M.bovis_AF2122/97 KVCSHLGCPSSLYEQQS------------------YRILCPCHQSQFDAL
Rv2195|M.tuberculosis_H37Rv KVCSHLGCPSSLYEQQS------------------YRILCPCHQSQFDAL
MLBr_00880|M.leprae_Br4923 KVCSHLGCPSSLYEQQS------------------YRILCPCHQSQFDAL
MMAR_4726|M.marinum_M NYCPHQGGPLCSGRARGRTMVDESAPGDAVMVRDLEFIYCPWHQWGFE-L
MUL_2161|M.ulcerans_Agy99 AYCEHLGAHLGYGGKVVG-----------------EVLQCPFHGWQWNQL
MAV_4414|M.avium_104 GVCTHQGCKLWFDAPDD-------------------TLRCPCHTTSFSPS
* * . : *. * :
MSMEG_1462|M.smegmatis_MC2_155 ETGEPICPP----ATVAIKTYPVEERDGEIFVGVEPGEMPVGPRRRRKGA
Mvan_1329|M.vanbaalenii_PYR-1 ETGEPISPP----ATEPIKTFPCEERDGEIFVGVEPGETPVGPARRARRV
Mflv_3012|M.gilvum_PYR-GCK SSGEEVSG-----AQMSVRSYPVEEIDGEIRLGLA---------------
MAB_4369c|M.abscessus_ATCC_199 KTGAVDGLP----ATKDTCPHRIEVRDGDIFLFPGEKPRPL---------
TH_4003|M.thermoresistible__bu ATGEVRRGP----AFEPVRSFEIRIDGDDIIVGL----------------
Mb2218|M.bovis_AF2122/97 HFAKPIFGP----AARALAQLPITIDTDGYLVANGDFVEPVGPAFWERTT
Rv2195|M.tuberculosis_H37Rv HFAKPIFGP----AARALAQLPITIDTDGYLVANGDFVEPVGPAFWERTT
MLBr_00880|M.leprae_Br4923 QYAKPIFGP----AARALAQLPITIDTDGYLVANGDFVEPVGPAFWERTT
MMAR_4726|M.marinum_M ATG-TTAVK----PEWSIRTYPVRVIGRDVLVMA----------------
MUL_2161|M.ulcerans_Agy99 GRNVCIPYQDRPNRGRRIRTYPVVERNASVYLWHDVEGRAPFFDAPDVFA
MAV_4414|M.avium_104 GKVLTHQLP---IEPKPLPALMVREADGIIEVFAPVRRT-----------
:
MSMEG_1462|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1329|M.vanbaalenii_PYR-1 L-------------------------------------------------
Mflv_3012|M.gilvum_PYR-GCK --------------------------------------------------
MAB_4369c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4003|M.thermoresistible__bu --------------------------------------------------
Mb2218|M.bovis_AF2122/97 T-------------------------------------------------
Rv2195|M.tuberculosis_H37Rv T-------------------------------------------------
MLBr_00880|M.leprae_Br4923 --------------------------------------------------
MMAR_4726|M.marinum_M --------------------------------------------------
MUL_2161|M.ulcerans_Agy99 GFNDGSSVADYYPQQRLYRHTLELHPQYVLENGVDFAHFKYVHNTPIVPV
MAV_4414|M.avium_104 --------------------------------------------------
MSMEG_1462|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1329|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3012|M.gilvum_PYR-GCK --------------------------------------------------
MAB_4369c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4003|M.thermoresistible__bu --------------------------------------------------
Mb2218|M.bovis_AF2122/97 --------------------------------------------------
Rv2195|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00880|M.leprae_Br4923 --------------------------------------------------
MMAR_4726|M.marinum_M --------------------------------------------------
MUL_2161|M.ulcerans_Agy99 FTRHDFDGPVSFVDFTITFEGDDGQQIEDINSGVEAINGGLGVAVTKSWG
MAV_4414|M.avium_104 --------------------------------------------------
MSMEG_1462|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1329|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3012|M.gilvum_PYR-GCK --------------------------------------------------
MAB_4369c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4003|M.thermoresistible__bu --------------------------------------------------
Mb2218|M.bovis_AF2122/97 --------------------------------------------------
Rv2195|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00880|M.leprae_Br4923 --------------------------------------------------
MMAR_4726|M.marinum_M --------------------------------------------------
MUL_2161|M.ulcerans_Agy99 MVDNRTISAITPVDESTSDVRFMVYIGRTPGKDPARAELKAAEFGREVIR
MAV_4414|M.avium_104 --------------------------------------------------
MSMEG_1462|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1329|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3012|M.gilvum_PYR-GCK --------------------------------------------------
MAB_4369c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4003|M.thermoresistible__bu --------------------------------------------------
Mb2218|M.bovis_AF2122/97 --------------------------------------------------
Rv2195|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00880|M.leprae_Br4923 --------------------------------------------------
MMAR_4726|M.marinum_M --------------------------------------------------
MUL_2161|M.ulcerans_Agy99 QFEPDIQIWAHQRYCDPPTLTTDELAGFTAIRRWAKQFYPDGISGSAAEV
MAV_4414|M.avium_104 --------------------------------------------------
MSMEG_1462|M.smegmatis_MC2_155 -------
Mvan_1329|M.vanbaalenii_PYR-1 -------
Mflv_3012|M.gilvum_PYR-GCK -------
MAB_4369c|M.abscessus_ATCC_199 -------
TH_4003|M.thermoresistible__bu -------
Mb2218|M.bovis_AF2122/97 -------
Rv2195|M.tuberculosis_H37Rv -------
MLBr_00880|M.leprae_Br4923 -------
MMAR_4726|M.marinum_M -------
MUL_2161|M.ulcerans_Agy99 YAALQKG
MAV_4414|M.avium_104 -------