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MVYLDYNASTPVDQRILPVVVESYGAHANAASTHHIAGRAAAELLEEARSRVAALVARSAQDVIFTSGAT EAAVLGLVGAVLGASGRPNVVVGATEHKAISAAAELGARLSGGEVRTVRANTNGVVDLTHVEALVDDSVA LVAVMAANNETGVLNPVGEVAEVARTAGALCFIDATQLVGKGNLDVATRSADLMVMSSHKIYGPKGAGAL IANRSVQKSLVAIASGGGQERGLRGGTHNTPSLVGFGLAAELAAKEQVDDAARLGKLASELLVDLQARLT GVTVNGGGAARLSNTLNLRFEGADAEAVMTSMPSVQVSAGSACQSAVPMPSHVLLAMGMSGTAAAESLRI SLGRPTTHDEIKIAGDAIVEAVTRVRELTRDEETRE
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1242 | iscS | - | 100% (386) | cysteine desulfurase IscS |
| M. smegmatis MC2 155 | MSMEG_2357 | - | 5e-50 | 33.68% (386) | cysteine desulfurase |
| M. smegmatis MC2 155 | MSMEG_4538 | - | 3e-23 | 27.00% (400) | cysteine desulphurase, SufS |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3051c | iscS | 5e-51 | 35.06% (385) | cysteine desulfurase IscS |
| M. gilvum PYR-GCK | Mflv_4255 | - | 2e-50 | 33.77% (385) | aminotransferase, class V |
| M. tuberculosis H37Rv | Rv3025c | iscS | 5e-51 | 35.06% (385) | cysteine desulfurase IscS |
| M. leprae Br4923 | MLBr_01708 | - | 2e-48 | 34.55% (385) | putative aminotransferase |
| M. abscessus ATCC 19977 | MAB_3357c | - | 2e-50 | 33.07% (384) | putative aminotransferase/cysteine desulfurase |
| M. marinum M | MMAR_1689 | iscS | 2e-53 | 35.84% (385) | cysteine desulfurase IscS |
| M. avium 104 | MAV_3872 | - | 5e-50 | 35.94% (384) | cysteine desulfurase |
| M. thermoresistible (build 8) | TH_1185 | - | 2e-51 | 34.81% (385) | PROBABLE CYSTEINE DESULFURASE ISCS (NIFS PROTEIN HOMOLOG) |
| M. ulcerans Agy99 | MUL_1927 | iscS | 2e-53 | 35.84% (385) | cysteine desulfurase IscS |
| M. vanbaalenii PYR-1 | Mvan_2105 | - | 3e-51 | 35.32% (385) | aminotransferase, class V |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3051c|M.bovis_AF2122/97 ------------------------------MAYLDHAATTPMHPAAIEAM
Rv3025c|M.tuberculosis_H37Rv ------------------------------MAYLDHAATTPMHPAAIEAM
MLBr_01708|M.leprae_Br4923 ----------------MIRQAPIAGILKCVMAYLDHAATTPMHPAAIEAM
MAV_3872|M.avium_104 ------------------------------MVYLDHAATTPMHPAAVEAM
MMAR_1689|M.marinum_M ------------------------------MVYLDHAATTPMHPTAIEAM
MUL_1927|M.ulcerans_Agy99 ------------------------------MVYLDHAATTPMHPTAIEAM
TH_1185|M.thermoresistible__bu -------------------------MNTPQTVYLDHAATTPMYPAAITAM
Mflv_4255|M.gilvum_PYR-GCK MRWSRERDRGARPRGRYPGTAMSASAAAPRPVYLDHAATTPMRPAAIEAM
Mvan_2105|M.vanbaalenii_PYR-1 ----------------MPG---------PAPVYLDHAATTPMRPGAIEAM
MAB_3357c|M.abscessus_ATCC_199 ---------------------------MSRSVYLDHAATTPMRPDAIEAM
MSMEG_1242|M.smegmatis_MC2_155 ------------------------------MVYLDYNASTPVDQRILPVV
.***: *:**: : .:
Mb3051c|M.bovis_AF2122/97 AAVQRTIGNASS-LHTSGRSARRRIEEARELIADKLGARPSEVIFTAGGT
Rv3025c|M.tuberculosis_H37Rv AAVQRTIGNASS-LHTSGRSARRRIEEARELIADKLGARPSEVIFTAGGT
MLBr_01708|M.leprae_Br4923 TTALGTVGNASS-LHTSGRVARRRIEESRELIADKLAARPSEVIFTAGGT
MAV_3872|M.avium_104 TAVLGTVGNASS-LHTSGRAARRRIEESRELVADKLGARPSEVIFTAGGT
MMAR_1689|M.marinum_M MAVLATVGNASS-LHTTGRAARRRLEESRELIAAKLGARPSEVIFTAGGT
MUL_1927|M.ulcerans_Agy99 TAVLATVGNASS-LHTTGRAARRRLEESRELIAAKLGARPSEVIFTAGGT
TH_1185|M.thermoresistible__bu TDVMSTVGNASS-LHSSGRVARRRMEEARETLARLLGARPSEVVFTAGGT
Mflv_4255|M.gilvum_PYR-GCK TAALATVGNASS-LHGSGRTARRRLEESRETLAQLLGARPSEVIFTAGGT
Mvan_2105|M.vanbaalenii_PYR-1 TAALATVGNAAS-LHGSGRLARRRLEESRETLARLLGARPSEVIFTAGGT
MAB_3357c|M.abscessus_ATCC_199 AATMAQTGNAAS-LHGAGRDARRRVEESRESIAAALGARPSEVIFTAGGT
MSMEG_1242|M.smegmatis_MC2_155 VESYGAHANAASTHHIAGRAAAELLEEARSRVAALVARSAQDVIFTSGAT
.**:* * :** * . :**:*. :* :. ..:*:**:*.*
Mb3051c|M.bovis_AF2122/97 ESDNLAVKGIYWARRDAEPHRRRIVTTEVEHHAVLDSVNWLVEHEGAHVT
Rv3025c|M.tuberculosis_H37Rv ESDNLAVKGIYWARRDAEPHRRRIVTTEVEHHAVLDSVNWLVEHEGAHVT
MLBr_01708|M.leprae_Br4923 ESDNLAVKGIYWARRDAQPCHRRIVTTEVEHHAVLDSVNWLVEHEGAEVT
MAV_3872|M.avium_104 ESDNLAVKGIYWARRDAEPRQRRIVTSEVEHHAVLDSVNWLVEHEGAEVT
MMAR_1689|M.marinum_M ESDNLAVKGMYWARRDAQPARRRIVTTRVEHHAVLDTVDWLVEHEGAEVT
MUL_1927|M.ulcerans_Agy99 ESDNLAVKGMYWARRDAQPARRRIVTTRVEHHAVLDTVDWLVEHEGAEVT
TH_1185|M.thermoresistible__bu ESDNLAVKGLYWARRAASPGLRRIITTRVEHHAVLDAVDWLVQHEGAEVT
Mflv_4255|M.gilvum_PYR-GCK ESDNLAVKGIYWARRDAEPQRRRIVTTPVEHHAVLDAVQWLADHEGAEVT
Mvan_2105|M.vanbaalenii_PYR-1 ESDNLVVKGIYWARRASSPKRRRIITTPVEHHAVLDAVEWLVEHEDAEVT
MAB_3357c|M.abscessus_ATCC_199 ESDNLAVKGIYWARRGADARRRRIIASAVEHHAVLDAVQWLADHEGAAVT
MSMEG_1242|M.smegmatis_MC2_155 EAAVLGLVGAVLG----ASGRPNVVVGATEHKAISAAAELGARLSGGEVR
*: * : * . . .::. .**:*: :.: . ... *
Mb3051c|M.bovis_AF2122/97 WLPTAADGSVSATALREALQSHDDVALVSVMWANNEVGTILPIAEMSVVA
Rv3025c|M.tuberculosis_H37Rv WLPTAADGSVSATALREALQSHDDVALVSVMWANNEVGTILPIAEMSVVA
MLBr_01708|M.leprae_Br4923 WLPTAADGSVSAFGLREALQQHNDVALVSVMWANNEVGTVMPVVELAAVA
MAV_3872|M.avium_104 WLPTAADGSVSPAALREVLTRHDDVALVSVMWANNEVGTVQPVAELAAVA
MMAR_1689|M.marinum_M WLPTDADGSVSASALRDALESHDDVALVSVMWANNEVGTIMPIAELAGVA
MUL_1927|M.ulcerans_Agy99 WLPTDADGSVSASALRDALESHDDVALVSVMWANNEVGTIMPIAELAGVA
TH_1185|M.thermoresistible__bu WLPVEPDGSVTPATLREALRAHDDVALVTLMWANNEVGTVSPIAELAAVA
Mflv_4255|M.gilvum_PYR-GCK WLPVDQYGAVNPADLRVALSETADVALVSVMWANNEVGTIQPIAELAAIA
Mvan_2105|M.vanbaalenii_PYR-1 WLPVDEFGAVGAADLRTALADPDDVALISVMWANNEVGTIMPIHELASVA
MAB_3357c|M.abscessus_ATCC_199 WLPVDQAGTVTPGALRAALAEHDDVALITVMWANNEVGTINPIYELSSIA
MSMEG_1242|M.smegmatis_MC2_155 TVRANTNGVVDLTHVEALVD--DSVALVAVMAANNETGVLNPVGEVAEVA
: . * * :. : .***:::* ****.*.: *: *:: :*
Mb3051c|M.bovis_AF2122/97 MEFGVPMHSDAIQAVGQLPLDFGASGLSAMSVAGHKFGGPPGVGALLLRR
Rv3025c|M.tuberculosis_H37Rv MEFGVPMHSDAIQAVGQLPLDFGASGLSAMSVAGHKFGGPPGVGALLLRR
MLBr_01708|M.leprae_Br4923 AEFGVPMHSDAIQAVGQLPVKFGVSGLSAMSVAAHKFGGPPGVGALLLRR
MAV_3872|M.avium_104 AEFGVPMHSDAVQAVGQLPVDFTASGLSAMSVTAHKFGGPPAVGALLLRR
MMAR_1689|M.marinum_M AEFGVPMHSDAVQAVGQVPVDFGACGLAAMSVTAHKFGGPPGAGALLMRR
MUL_1927|M.ulcerans_Agy99 AEFGVPMHSDAVQAVGQIPVDFGACGLAAMSVTAHKFGGPPGAGALLMRR
TH_1185|M.thermoresistible__bu AEFSVPMHSDAVQAVGHLPVDFSASGLSAMSISAHKFGGPTGVGALLIRR
Mflv_4255|M.gilvum_PYR-GCK TEFGVPMHSDAIQAIGQLPVDFGASGLSAMSVAAHKFGGPAGVGALLLRR
Mvan_2105|M.vanbaalenii_PYR-1 AEFEIPMHSDAIQVVGQLPVDFAASGLSAMSVTAHKFGGPIGVGALLLRR
MAB_3357c|M.abscessus_ATCC_199 AEFDVPMHSDAIGAVGQLDVDFALSGLSAISVAAHKFGGPMGVGALLLRR
MSMEG_1242|M.smegmatis_MC2_155 RTAGALCFIDATQLVGKGNLDVATRSADLMVMSSHKIYGPKGAGALIANR
. ** :*: :.. . : ::.**: ** ..***: .*
Mb3051c|M.bovis_AF2122/97 --DVTCVPLMHGGGQERDIRSGTPDVASAVGMATAAQIAVDGLEENSARL
Rv3025c|M.tuberculosis_H37Rv --DVTCVPLMHGGGQERDIRSGTPDVASAVGMATAAQIAVDGLEENSARL
MLBr_01708|M.leprae_Br4923 --DISCVPLLHGGGQERDIRSGTPGVASVVGMAAAAQIAVDGLEINSIRL
MAV_3872|M.avium_104 --DVACVPLAHGGGQERDIRSGTADVAGAVGMAAAARISVDGLETNSARL
MMAR_1689|M.marinum_M --DVSCVPLLHGGGQERDIRSGTPDVASAVGMAAAARIAVDGLEANSARL
MUL_1927|M.ulcerans_Agy99 --DVSCVPLLHGGGQERDIRSGTPDVASAVGIAAAARIAVDGLEANSARL
TH_1185|M.thermoresistible__bu --DAECVPLLHGGGQERDIRSGTPHVAGVVAMAVAAEAAIENLPAVSARI
Mflv_4255|M.gilvum_PYR-GCK --DTACVPQLHGGGQERDVRSGTQDVAGVIGMAVAARDAADTMEPVIARV
Mvan_2105|M.vanbaalenii_PYR-1 --ETACVPLLHGGGQERDVRSGTQDVPGAVGMAAAAQIAADTMDSAAEKV
MAB_3357c|M.abscessus_ATCC_199 --EIACVPLLHGGGHERDIRSGTPDTAAIVAMSTALVAAVAERCESAAAM
MSMEG_1242|M.smegmatis_MC2_155 SVQKSLVAIASGGGQERGLRGGTHNTPSLVGFGLAAELAAKEQVDDAARL
: *. ***:**.:*.** ... :.:. * : :
Mb3051c|M.bovis_AF2122/97 RLLRDRLVEGVLAEIDDVCLNGADDPMRLAGNAHFTFRGCEGDALLMLLD
Rv3025c|M.tuberculosis_H37Rv RLLRDRLVEGVLAEIDDVCLNGADDPMRLAGNAHFTFRGCEGDALLMLLD
MLBr_01708|M.leprae_Br4923 QVLRDRLIEGVLATIDDVALNGARDRMRLPGNAHFIFRGCEGDVLLMLLD
MAV_3872|M.avium_104 RALRDRLVDGVLGGIEDVTLNGARDPLRLPGNAHFTFRGCEGDALLMLLD
MMAR_1689|M.marinum_M QTLRDRLVAGVLAEIDDVRLNGARDPLRLPGNAHFTFRGCEGDALLMLLD
MUL_1927|M.ulcerans_Agy99 QTLRDRLVAGVLAEIDDVRLNGARDPLRLPGNAHFTFRGCEGDALLMLLD
TH_1185|M.thermoresistible__bu AALRDRLIDGVLTGIDDAYLNGARGADRLPGNAHFTFRGCEGDSLLMLLD
Mflv_4255|M.gilvum_PYR-GCK RDLRDRLVAGVLESIDDVDVNGAPGPGRLPGNAHFTFRGCEGDSLLMLLD
Mvan_2105|M.vanbaalenii_PYR-1 RALRDRLIDGVLDAVDDVDVNGAPGAGRLPGNAHFTFRGCEGDSLLMLLD
MAB_3357c|M.abscessus_ATCC_199 AGLRDSLIDQVLTQIEGATLNGAPGSGRLPGNAHFTFAGCEGDSLLMLLD
MSMEG_1242|M.smegmatis_MC2_155 GKLASELLVDLQARLTGVTVNGG-GAARLSNTLNLRFEGADAEAVMTSMP
* . *: : : .. :**. . **... :: * *.:.: :: :
Mb3051c|M.bovis_AF2122/97 ANGIECSTGSACTAGVAQPSHVLIAMGVDAASARGSLRLSLGHTSVEADV
Rv3025c|M.tuberculosis_H37Rv ANGIECSTGSACTAGVAQPSHVLIAMGVDAASARGSLRLSLGHTSVEADV
MLBr_01708|M.leprae_Br4923 ANGIECSTGSACTSGVPQPSHVLIAMGADPASARGSLRLSLGHNSVEVDV
MAV_3872|M.avium_104 ANGIECSTGSACTAGVAQPSHVLVAMGVDPASARGSLRLSLGHTSIDADV
MMAR_1689|M.marinum_M ANGIECSTGSACTAGVAQPSHVLIAMGADPASARGSLRLSLGHTTVEADV
MUL_1927|M.ulcerans_Agy99 ANGIECSTGSACTAGVAQPSHVLIAMGADPASARGSLRLSLGHTTVEADV
TH_1185|M.thermoresistible__bu ANGIECSTGSACTAGVAQPSHVLIAMGADSASARGSLRLSLGHTSTEADV
Mflv_4255|M.gilvum_PYR-GCK AKGIECSTGSACTAGVAQPSHVLTAMGVDPASARGSLRLSLGHTSTEADI
Mvan_2105|M.vanbaalenii_PYR-1 AKGIECSTGSACTAGVAQPSHVLTAMGADPVSARGSLRLSLGHTSTDADI
MAB_3357c|M.abscessus_ATCC_199 ANGIECSTGSACTAGVARPSHVLIEMGIDPEVARGSLRFTFGHTSVPSDV
MSMEG_1242|M.smegmatis_MC2_155 S--VQVSAGSACQSAVPMPSHVLLAMGMSGTAAAESLRISLGRPTTHDEI
: :: *:**** :.*. ***** ** . * ***:::*: : ::
Mb3051c|M.bovis_AF2122/97 DAALEVLPGAVARARRAALAAAGASR---
Rv3025c|M.tuberculosis_H37Rv DAALEVLPGAVARARRAALAAAGASR---
MLBr_01708|M.leprae_Br4923 EEVLRVLPGAVDRARRASLAAAGAGGVGV
MAV_3872|M.avium_104 DAVLRVLPGAVERARRAALAAAGAS----
MMAR_1689|M.marinum_M DAALQVLPAAVARARSAAVAAAGAAW---
MUL_1927|M.ulcerans_Agy99 DAALQVLPAAVARARSAAVAAAGAAW---
TH_1185|M.thermoresistible__bu DAALAVLPAAVERARQAALASAGVDK---
Mflv_4255|M.gilvum_PYR-GCK EAVLEVLPAAVDRARQAALASSGRH----
Mvan_2105|M.vanbaalenii_PYR-1 DAVLDVLPAAVERARQAALASSGRR----
MAB_3357c|M.abscessus_ATCC_199 DRALEALHAAVPRARAAALASAGGRS---
MSMEG_1242|M.smegmatis_MC2_155 KIAGDAIVEAVTRVRELTRDEETRE----
. . .: ** *.* :