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MSRVFDTEVVTRSVVILGYSGVQALDLVGPFDVFTGAALWLAGQGREQQAYTVTLASADGAPVTTLTGLE FVAAPPPDPCGDIDTVVIPGGIGADEARRNREVVNWIKTAADHARRVVTVCTGAFLAAEAGLLDGCPATT HWASARRLADEFPSVTVDPEPIFMRSSERVWTAAGVTAGIDLALSLVEDDHGTDVAQNVARWLVLYLRRP GGQTQFAAPVWMPRAKRAPIRAVQEAIEADPGGAHSISDLAQRAAMSPRHFTRVFTEEVGQSPGVYVERI RIDAARRQLEESDDTVTAIAARCGFGTAETMRRNFIRRLGVSPDQYRKTSALTGR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1106 | - | - | 100% (335) | transcriptional regulator, AraC family protein |
| M. smegmatis MC2 155 | MSMEG_3365 | - | e-116 | 64.35% (317) | transcriptional regulator, AraC family protein |
| M. smegmatis MC2 155 | MSMEG_3488 | - | 5e-63 | 42.41% (316) | transcriptional regulator, AraC family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1966c | - | 1e-52 | 46.52% (273) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_5267 | - | 1e-133 | 71.43% (322) | AraC family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1931c | - | 1e-52 | 46.52% (273) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0942 | - | 1e-128 | 68.52% (324) | AraC family transcriptional regulator |
| M. marinum M | MMAR_2855 | - | 1e-130 | 71.74% (322) | transcriptional regulatory protein |
| M. avium 104 | MAV_4981 | - | 4e-67 | 42.59% (324) | transcriptional regulator, AraC family protein |
| M. thermoresistible (build 8) | TH_3120 | - | 9e-43 | 38.60% (272) | PUTATIVE transcriptional regulator, AraC family with |
| M. ulcerans Agy99 | MUL_2902 | - | 1e-129 | 71.43% (322) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_0972 | - | 1e-135 | 72.09% (326) | AraC family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1966c|M.bovis_AF2122/97 -------------------MVIVGFPG-----------------------
Rv1931c|M.tuberculosis_H37Rv -------------------MVIVGFPG-----------------------
Mflv_5267|M.gilvum_PYR-GCK ---------------MTRTVLIVGFAGVQALDIVGPFDVFTGASLAVTAR
Mvan_0972|M.vanbaalenii_PYR-1 MHGLDAIAALANTEPMVRTVVIVGFAGVQALDVVGPFDVFTGASLSVGAR
MAB_0942|M.abscessus_ATCC_1997 ---------------MRRSVVILGFPGVQALDLVGPYEVFATASRHMTGT
MSMEG_1106|M.smegmatis_MC2_155 ------MSRVFDTEVVTRSVVILGYSGVQALDLVGPFDVFTGAALWLAGQ
MMAR_2855|M.marinum_M ---------------MARKVVIVGFPGVQPLDVVGPFEVFAGASLLSEG-
MUL_2902|M.ulcerans_Agy99 ---------------MARKVVTVGFPGVQPLDVVGPFEVFAGASLLSEG-
MAV_4981|M.avium_104 ---------MADSSATPRVVVIVVFDDVTMLDVAGAGEVFAEANRFGAD-
TH_3120|M.thermoresistible__bu -------------------VAALVLDGLAIFEFGVICEVFGVDRTDDGVP
: : .
Mb1966c|M.bovis_AF2122/97 ---------------------------------DP---VDTVILPGGAGV
Rv1931c|M.tuberculosis_H37Rv ---------------------------------DP---VDTVILPGGAGV
Mflv_5267|M.gilvum_PYR-GCK G--GDGYAVTVVSVGGDPVSTGTGLTLTAVPLPDPGHPIDTLVLPGGFGA
Mvan_0972|M.vanbaalenii_PYR-1 GL-GDGYDVRVVAVDGAPVSTGTGLTLAADPLPGPDEAVDTVVLPGGWGA
MAB_0942|M.abscessus_ATCC_1997 T---PGYDVKLVSADGAPVSTGSGMELVTQPLPDPEPGCDTLLLPGGIGV
MSMEG_1106|M.smegmatis_MC2_155 GREQQAYTVTLASADGAPVTTLTGLEFVAAPPPDPCGDIDTVVIPGGIGA
MMAR_2855|M.marinum_M -----GYDVALASIDERPVATGIGLEFMTTRLPDPSAPVDTVVLPGGGGV
MUL_2902|M.ulcerans_Agy99 -----GYDVALASIDERPVATGIGLEFMTTRLPDPSAPVDTVVLPGGGGV
MAV_4981|M.avium_104 ------YLLKIASVDGRDVTTSIGTRLGVTDAVSSIESADTVLVAGSDNL
TH_3120|M.thermoresistible__bu P----VDFTVCGPRAGQPVRTSFGATLTPDSGLDGLAGADLVAIP---AI
. * : :.
Mb1966c|M.bovis_AF2122/97 DAARSEPALIDWVKAVSGTARRVVTVCTGAFLAAEAGLLGRTPSDDALGL
Rv1931c|M.tuberculosis_H37Rv DAARSEPALIDWVKAVSGTARRVVTVCTGAFLAAEAGLLGRTPSDDALGL
Mflv_5267|M.gilvum_PYR-GCK DAARRDDVLIDWITAIAPHARRVVSVCSGAVLAAQAGLLDGCVATTHWAY
Mvan_0972|M.vanbaalenii_PYR-1 DTARRDQVLIDWITAAAARARRVVSVCNGAVLAAQAGLLDGCVATTHWAY
MAB_0942|M.abscessus_ATCC_1997 SAVQRDAALMSWVRAAARGARRVVSVCNGAFLAAEAGLLDGCRATTHWAI
MSMEG_1106|M.smegmatis_MC2_155 DEARRNREVVNWIKTAADHARRVVTVCTGAFLAAEAGLLDGCPATTHWAS
MMAR_2855|M.marinum_M DAARDNVALMDWVKAAAGTARRVVTVCTGTFLAAEAGLLDGCRATTHWAF
MUL_2902|M.ulcerans_Agy99 DAARDNVALMDWVKAAAGTARRVVTVCTGTFLAAEAGLLDGCRATTHWAF
MAV_4981|M.avium_104 PRRPIDPELVEAVKSVADRTRRLASICTGSFILGQAGLLDGRRATTHWHD
TH_3120|M.thermoresistible__bu RQDDYLPEALDAVRAAADAGAIILTVCSGAFLAGAAGLLDGRPCTTHWGL
:. : : : : ::*.*:.: . ****. .
Mb1966c|M.bovis_AF2122/97 CRTFRPRISGRSGR-----CRPDLHAQFAEGVDRGWSHRRHRPRAGTGRR
Rv1931c|M.tuberculosis_H37Rv CRTFRPRISGRSGR-----CRPDLHAQFAEGVDRGWSHRRHRPRAGTGRR
Mflv_5267|M.gilvum_PYR-GCK APHMAVEFPSVTVDPDPIFVRSSEKVWTAAGVTAGIDLALSLVEDDHGTE
Mvan_0972|M.vanbaalenii_PYR-1 APQLAAEFPSVTVDPDPIFVRSSEKVWTAAGVTAGIDLALALVEDDHGTE
MAB_0942|M.abscessus_ATCC_1997 AGQLASEFPSVTVDPDPIFIRSSDKTWTAAGVTAGIDLALALVEEDHGAE
MSMEG_1106|M.smegmatis_MC2_155 ARRLADEFPSVTVDPEPIFMRSSERVWTAAGVTAGIDLALSLVEDDHGTD
MMAR_2855|M.marinum_M ADRLAREFPAVDVDPDPIFIRSSPKVWTAAGVTAGIDLALALVEGDHGTE
MUL_2902|M.ulcerans_Agy99 ADRLAREFPAVDVDPDPIFIRSSPKVWTAAGVTAGIDLALALVEGDHGTE
MAV_4981|M.avium_104 VRLFARAFPEITVEPDALFVCDG-DVFTSAGISSGIDLALALVEMDYGTE
TH_3120|M.thermoresistible__bu TEELARRYPTARVDRNVLYVDDG-DLITSAGTAAGIDACLHLVRRELGSE
: . . : * * . . *
Mb1966c|M.bovis_AF2122/97 RPRHRDCPDGCPLARPVSAPTRWADPVRGSGVDATRQTDLDPPGAGGHRG
Rv1931c|M.tuberculosis_H37Rv RPRHRDCPDGCPLARPVSAPTRWADPVRGSGVDATRQTDLDPPGAGGHRG
Mflv_5267|M.gilvum_PYR-GCK LAQTVARHLVMYLRRPGGQ-TQFAAPVWMPRARRSPIRDVQEVIES----
Mvan_0972|M.vanbaalenii_PYR-1 TAQIVARHLVMYLRRPGGQ-TQFAAPVWMPRARRTPIRDVQEAVEA----
MAB_0942|M.abscessus_ATCC_1997 VAQAVARWLVLYLRRPGGQ-SQFAAPVWMPRAKRMPIRDVQEAIEA----
MSMEG_1106|M.smegmatis_MC2_155 VAQNVARWLVLYLRRPGGQ-TQFAAPVWMPRAKRAPIRAVQEAIEA----
MMAR_2855|M.marinum_M IAQTVARWLVLYLRRPGGQ-TQFAAPVWMPRAKRPSIRDVQEAIEA----
MUL_2902|M.ulcerans_Agy99 IAQTVARWLVLYLRRPCGQ-TQFAAPVWMPRAKRPSIRDVQEAIEA----
MAV_4981|M.avium_104 LVRAVARWLVVYLKRAGGQ-SQFSALVEAEPPPRSPLRKVTAAISA----
TH_3120|M.thermoresistible__bu VTNTIARHMVVPPQRDGGQ-RQFIDQPIPVRHSEGFAPHLDWILSN----
. * . :: :
Mb1966c|M.bovis_AF2122/97 RAGGAHRIGELAQRAAMSPRHFTRVFSDEVGEAPGRYVERIRTEAARRQL
Rv1931c|M.tuberculosis_H37Rv RAGGAHRIGELAQRAAMSPRHFTRVFSDEVGEAPGRYVERIRTEAARRQL
Mflv_5267|M.gilvum_PYR-GCK EPGAVHSISELARRAAMSTRHFTRAFTDEVGEAPGAYVERVRTEAARRQL
Mvan_0972|M.vanbaalenii_PYR-1 EPGGAHSIAELARLAAMSPRHFTRVFTEEVGEAPGAYVERVRTEAARRQL
MAB_0942|M.abscessus_ATCC_1997 EPSGSHRVPELARLAAMSPRHFTRVFTAEVGEAPSAYVERIRSEAARRQL
MSMEG_1106|M.smegmatis_MC2_155 DPGGAHSISDLAQRAAMSPRHFTRVFTEEVGQSPGVYVERIRIDAARRQL
MMAR_2855|M.marinum_M QPGGPHSIEELAHRAAMSPRHFTRVFTGEVGEAPRQYVERVRTEAARRQL
MUL_2902|M.ulcerans_Agy99 QPGGPHSIEELAHRAAMSPRHFTRVFTGEVGEAPGRYVERVRTEAARRQL
MAV_4981|M.avium_104 DPAADHSVKSLSARASLSTRQLTRLFQSELGTTPARYVEMVRIDAARAAL
TH_3120|M.thermoresistible__bu -LDKTHTVASLARRANMSPRTFARRFVEETGRTPMQWVTDQRVLYARRLL
* : .*: * :*.* ::* * * * :* :* * ** *
Mb1966c|M.bovis_AF2122/97 EETHDTVVAIAARCGFGTAETMRRSFIRRVGISPDQYRKAFA--------
Rv1931c|M.tuberculosis_H37Rv EETHDTVVAIAARCGFGTAETMRRSFIRRVGISPDQYRKAFA--------
Mflv_5267|M.gilvum_PYR-GCK EETDDTVTVIAARCGFGSAETLRRSFVRRLGVSPDQYRKTFA--------
Mvan_0972|M.vanbaalenii_PYR-1 EETDDTVTVIAARCGFGSAETLRRNFVRRLGVSPDQYRRTFA--------
MAB_0942|M.abscessus_ATCC_1997 EETDDTMVVIAGRCGFGSAESLRRNFVRRMGVSPDQYRKTFQRTDRSSV-
MSMEG_1106|M.smegmatis_MC2_155 EESDDTVTAIAARCGFGTAETMRRNFIRRLGVSPDQYRKTSALTGR----
MMAR_2855|M.marinum_M EETEDTVVAIAARCGFGTAETMRRNFIRRVGISPDQYRKAFA--------
MUL_2902|M.ulcerans_Agy99 EETEDTVVAIAARCGFGTAETMRRNFIRRVGISPDQYRKAFA--------
MAV_4981|M.avium_104 DAG-RSVAESARLAGFGSAETLRRVFVEHLGLSPKAYRDRFRTAARG---
TH_3120|M.thermoresistible__bu EETDLDIHRIAARCGFGSTTLLRHHFRRVIGVTPSDYRRRFACGSTTSGS
: : * .***:: :*: * . :*::*. **
Mb1966c|M.bovis_AF2122/97 ---------
Rv1931c|M.tuberculosis_H37Rv ---------
Mflv_5267|M.gilvum_PYR-GCK ---------
Mvan_0972|M.vanbaalenii_PYR-1 ---------
MAB_0942|M.abscessus_ATCC_1997 ---------
MSMEG_1106|M.smegmatis_MC2_155 ---------
MMAR_2855|M.marinum_M ---------
MUL_2902|M.ulcerans_Agy99 ---------
MAV_4981|M.avium_104 ---------
TH_3120|M.thermoresistible__bu TESGAEVTD