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VAPSLKVPDAAAASVFNAVRLRGPIARDVIAQHTSLSIATVNRQVTALLEAGVLRERADLAVSGAIGRPR VPVEVNHEPYLTLGVHIGAKTTAIVATDLLGRTLDVVETPTPTGTQAAALATLASSARRYLSRWHRRRPL WVGVAAGGVVDSATGYLDHPRLGWADAPVGPVLAEALGLPVSMASHVDAMAGAELLLSGRRAENAGGASR TSLYVYARETVGYALSIDGRVHSPASGPGTIAGLPARSELLGGTGQLESTVSDEAVLNAARRLRIVPAEG PASTLPAVLRAARGGNEKAVELLADRARVLGEAVALLRDMLNPDELVVGGQAFTEYPEGMEAVEAAFAER SMLGPRDIRLTAFGNRVQEAGAGVVSLGGLYADPIGAMRRAQTRRAAAV
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. smegmatis MC2 155 | MSMEG_0932 | - | - | 100% (399) | ROK family protein |
M. smegmatis MC2 155 | MSMEG_0316 | - | 1e-13 | 25.06% (391) | putative NagC regulator |
M. smegmatis MC2 155 | MSMEG_6022 | - | 8e-13 | 26.46% (393) | xylose repressor, ROK-family protein transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0495 | - | 1e-163 | 75.25% (396) | transcriptional regulatory protein |
M. gilvum PYR-GCK | Mflv_0087 | - | 0.0 | 83.25% (394) | ROK family protein |
M. tuberculosis H37Rv | Rv0485 | - | 1e-163 | 75.25% (396) | transcriptional regulatory protein |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_4059c | - | 1e-166 | 75.25% (396) | hypothetical protein MAB_4059c |
M. marinum M | MMAR_0811 | - | 1e-167 | 77.33% (397) | transcriptional regulatory protein |
M. avium 104 | MAV_4665 | - | 1e-168 | 77.83% (397) | ROK family protein |
M. thermoresistible (build 8) | TH_0877 | - | 1e-168 | 76.98% (391) | POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN |
M. ulcerans Agy99 | MUL_4555 | - | 1e-166 | 76.83% (397) | transcriptional regulatory protein |
M. vanbaalenii PYR-1 | Mvan_0826 | - | 1e-171 | 78.57% (406) | ROK family protein |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_0087|M.gilvum_PYR-GCK -MSTTTLAPRTRTTSAENAAAKRPAAGGRYPQALLHQIVAPSLCLPEAAA Mvan_0826|M.vanbaalenii_PYR-1 -MSTSTLAQRPRAASVTRTG---PATGGRYPHALLHHIVAPALRVPEAAA MSMEG_0932|M.smegmatis_MC2_155 --------------------------------------MAPSLKVPDAAA TH_0877|M.thermoresistible__bu VARTANTVSTPRTASSLLRPAGVTASRTRRPLVSRQRVVAPSLRVADAAA Mb0495|M.bovis_AF2122/97 -----------MYSTNRTSQSLSRKPGRKHQLRSHRYVMPPSLHLSDSAA Rv0485|M.tuberculosis_H37Rv -----------MYSTNRTSQSLSRKPGRKHQLRSHRYVMPPSLHLSDSAA MMAR_0811|M.marinum_M -------------------------------------MVAPSLHLADSAA MUL_4555|M.ulcerans_Agy99 -------------------------------------MVAPSLHLADSAA MAV_4665|M.avium_104 ---------------------MGHAPGPKPHRAVRRQIVPPALHIPESAA MAB_4059c|M.abscessus_ATCC_199 ------------------------MTAPVRRPVSRHQIHPPALYIGDSAA .*:* : ::** Mflv_0087|M.gilvum_PYR-GCK ASVFAAARQRGPIARDVIAQVTGLSIATVNRQVTALLDAGLLRERADLAV Mvan_0826|M.vanbaalenii_PYR-1 AAVLAAARQRGPIARDVIAQVTGLSIATVNRQVTALLEVGLLRERADLAV MSMEG_0932|M.smegmatis_MC2_155 ASVFNAVRLRGPIARDVIAQHTSLSIATVNRQVTALLEAGVLRERADLAV TH_0877|M.thermoresistible__bu ASVFEAARLRGPIARDAIAKATGLSIATVNRQVIALLEAGLLRERPDLAV Mb0495|M.bovis_AF2122/97 ASVFRAVRLRGPVGRDVIAGSTSLSIATVNRQVIALLEAGLLRERADLAV Rv0485|M.tuberculosis_H37Rv ASVFRAVRLRGPVGRDVIAGSTSLSIATVNRQVIALLEAGLLRERADLAV MMAR_0811|M.marinum_M ASVFRAVRLRGPVGRDVIATTTSLSIATVNRQVIALLDAGLLRERADLAV MUL_4555|M.ulcerans_Agy99 ASVFRAVRLRGPVGRDVIATTTSLSIATVNRQVIALLDAGLLWERADLAV MAV_4665|M.avium_104 ASVFRAVRLRGPVGRDVIANVTSLSIATVNRQVIALLEAGLLRERADLAV MAB_4059c|M.abscessus_ATCC_199 SSVFRAARVRGPVARDAIAQVTGLSIATVNRQVTALLDAGLLRERADLAV ::*: *.* ***:.**.** *.********** ***:.*:* **.**** Mflv_0087|M.gilvum_PYR-GCK SGAIGRPRVPVEVNHEPFLTLGIHIGARTTSIVAADLFGRTLDVVETPTP Mvan_0826|M.vanbaalenii_PYR-1 SGAIGRPRVPVEVNHGPFLTLGIHIGARTTSIVATDLLGRTLDVVETATP MSMEG_0932|M.smegmatis_MC2_155 SGAIGRPRVPVEVNHEPYLTLGVHIGAKTTAIVATDLLGRTLDVVETPTP TH_0877|M.thermoresistible__bu SGAIGRPRVPVEVDHDPYLTLGIHIGARTTSIAATDLFGRTLDVVETPTP Mb0495|M.bovis_AF2122/97 SGAIGRPRVPVEVNHEPFVTLGIHIGARTTSIVATDLFGRTLDTVETPTP Rv0485|M.tuberculosis_H37Rv SGAIGRPRVPVEVNHEPFVTLGIHIGARTTSIVATDLFGRTLDTVETPTP MMAR_0811|M.marinum_M SGAIGRPRVPVEVNHEPFVTLGLHIGARTTSIVATDLLGRTLDTVETATP MUL_4555|M.ulcerans_Agy99 SGAIGRPRVPVEVNHEPFVTLGLHIGARTTSIVATDLLGRTLDTVETATP MAV_4665|M.avium_104 SGAIGRPRVPVEVNHEPFVTLGIHIGARTTSIVATDLFGRTLDTVETPTP MAB_4059c|M.abscessus_ATCC_199 SGAIGRPRVPVELNHEPFLTLGIHIGARATSIVATDLFGRTLDVVETPTP ************::* *::***:****::*:*.*:**:*****.***.** Mflv_0087|M.gilvum_PYR-GCK RGPQAVALTAIAGSASRYLSR--------WHRRRPLWVGVATGGVVDSAT Mvan_0826|M.vanbaalenii_PYR-1 RGPQAAALAAVAGSARRYLSRPPRAGGAPRRRRRPLWVGVATGGVVDSAT MSMEG_0932|M.smegmatis_MC2_155 TGTQAAALATLASSARRYLSR--------WHRRRPLWVGVAAGGVVDSAT TH_0877|M.thermoresistible__bu RGAQPGAVASLAESARRYLSR--------WHRRRPLWVGVAAGGVFDVTT Mb0495|M.bovis_AF2122/97 RNAAGAALTSLADSADRYLQR--------WRRRRALWVGVTLGGAVDSAT Rv0485|M.tuberculosis_H37Rv RNAAGAALTSLADSADRYLQR--------WRRRRALWVGVTLGGAVDSAT MMAR_0811|M.marinum_M RSSASSALASLADSAGRYLRR--------WHRRRALWVGVAIGGTVDDAS MUL_4555|M.ulcerans_Agy99 RSSASSALASLADSAGRYLRR--------WHRRRALWVGVAIGGTVDDAS MAV_4665|M.avium_104 RNPAGPALASLADSARRYLRR--------WHRRRPLWIGVAIGGTVDSAT MAB_4059c|M.abscessus_ATCC_199 NGPQGAALASLAGSAQRYLAR--------WHRRRPLWVGVATGGVVDGPA .. *::::* ** *** * :***.**:**: **..* .: Mflv_0087|M.gilvum_PYR-GCK GYLDHPRLGWADAPVGPVLAETLGLPVSVASHVDAMAGAELLLGVRRRP- Mvan_0826|M.vanbaalenii_PYR-1 GYVNHPRLGWSDAPVGTVLGEALGLPVSLASHVDAMAGAELLLGVRRQP- MSMEG_0932|M.smegmatis_MC2_155 GYLDHPRLGWADAPVGPVLAEALGLPVSMASHVDAMAGAELLLSGRRAEN TH_0877|M.thermoresistible__bu GHLDHPLLGWTDAPVGPVLAETLGLPVSVAPHLDAMAAAELLLGRSRRR- Mb0495|M.bovis_AF2122/97 GHVDHPRLGWRQAPVGPVLADALGLPVSVASHVDAMAGAELMLGMRRFAP Rv0485|M.tuberculosis_H37Rv GHVDHPRLGWRQAPVGPVLADALGLPVSVASHVDAMAGAELMLGMRRFAP MMAR_0811|M.marinum_M GHVDHQRLGWRQAPVGPALADALGLPVSVASHVDAMAGAELLLGTRRLAG MUL_4555|M.ulcerans_Agy99 GHVDHQRLGWRHAPVGPALADALGLPVSVASHVDAMAGAELLLGTRRLAG MAV_4665|M.avium_104 GQVDHPRLGWRQAPVGQVLADALGLPVSVASHVDAMAGAELLLGMRRFLP MAB_4059c|M.abscessus_ATCC_199 GTVDHPRLGWTEAPVGRVFADTLGLPVSVASHVDAMAGAELLLGLRRFAA * ::* *** .**** .:.::******:*.*:****.***:*. * Mflv_0087|M.gilvum_PYR-GCK --GKAATGLYVYARETVGYALSIGGRVHSPTSGPGTIASLPVRSELLGGT Mvan_0826|M.vanbaalenii_PYR-1 --AKSTTSLYVYARETVGYALSIGGQVHSPSSGPGTIAALPAFSELLGGT MSMEG_0932|M.smegmatis_MC2_155 AGGASRTSLYVYARETVGYALSIDGRVHSPASGPGTIAGLPARSELLGGT TH_0877|M.thermoresistible__bu ----GTTSLFMYARETVGYALSIAGRVHSPAAGPGTIAALPVNSDLLGGT Mb0495|M.bovis_AF2122/97 ---SSSTSLYVYARETVGYALMIGGRVHCPASGPGTIAPLPVHSEMLGGT Rv0485|M.tuberculosis_H37Rv ---SSSTSLYVYARETVGYALMIGGRVHCPASGPGTIAPLPVHSEMLGGT MMAR_0811|M.marinum_M ---GSSTSLYVYARETVGYALVIDGRVHCPASGPGTIAGLPAHSELLGGT MUL_4555|M.ulcerans_Agy99 ---GSSTSLYVYARETVGYALVIDGRVHCPASGPGTIAGLPAHSELLGGT MAV_4665|M.avium_104 ---SSPTSLYVYARETVGYALVIGGRVHVPTSGPGTIATLPAHSELLGGT MAB_4059c|M.abscessus_ATCC_199 ---RSLTSLYVYARETVGFALAIDGRVHSPSSGPGTIAALPVDSELLGGS . *.*::*******:** * *:** *::****** **. *::***: Mflv_0087|M.gilvum_PYR-GCK GQLESTVSDEAVLTAARRAGVVPADG-------PASTVTAVLRAARQGDE Mvan_0826|M.vanbaalenii_PYR-1 GQLESTVSDEAVLTAARKAGIVAAEG-------PTSTVTAVLRAARQGNA MSMEG_0932|M.smegmatis_MC2_155 GQLESTVSDEAVLNAARRLRIVPAEG-------PASTLPAVLRAARGGNE TH_0877|M.thermoresistible__bu GQLETTVSDQAVVTAARRLNVIPPEG-------PASTIAAVLRAAQRGDS Mb0495|M.bovis_AF2122/97 GQLESTVSDEAVLAAARRLRIIPGIASRTRTGGSATAITDLLRVARAGNQ Rv0485|M.tuberculosis_H37Rv GQLESTVSDEAVLAAARRLRIIPGIASRTRTGGSATAITDLLRVARAGNQ MMAR_0811|M.marinum_M GQLESTVSDEAVLAAARRLRIIAATP-QARTNGSVTAMTDLLRVARAGNQ MUL_4555|M.ulcerans_Agy99 GQLESTVSDEAVLAAARRLRIIAATP-QARTNGSITAMTDLLRVARAGNQ MAV_4665|M.avium_104 GQLESTVSDEAVVAVARQLRILPFAP-ANRASGSAAGIADLLRVARAGNE MAB_4059c|M.abscessus_ATCC_199 GKLETTVSDEAVLAAARKLRIVPAGD--------GVSVSAVYKAARGGNE *:**:****:**: .**: ::. :. : :.*: *: Mflv_0087|M.gilvum_PYR-GCK HAVALIAERARVLGEAVALLRDMLNPDDLVVGGQAFTEYPEGMSIVEEAF Mvan_0826|M.vanbaalenii_PYR-1 AAAALVAERARVLGEAVALLRDMLNPDDLVVGGQAFTEYPEGMPLVESAF MSMEG_0932|M.smegmatis_MC2_155 KAVELLADRARVLGEAVALLRDMLNPDELVVGGQAFTEYPEGMEAVEAAF TH_0877|M.thermoresistible__bu TARELLDERARVLGESLALLRDMLNPDEVVVGGQAFTDYPAGMETLTAAF Mb0495|M.bovis_AF2122/97 QAKELLAERARVLGGAVALLRDLLNPDEVVVGGQAFTEYPEAMEQVEAAF Rv0485|M.tuberculosis_H37Rv QAKELLAERARVLGGAVALLRDLLNPDEVVVGGQAFTEYPEAMEQVEAAF MMAR_0811|M.marinum_M QARELLAERARVLGETVALLRDVLNPDELVVGGQAFTEYPEGMRQVEEAF MUL_4555|M.ulcerans_Agy99 QARELLAERARVLGETVALLRDVLNPDELVVGGQAFTEYPEGMRQVKEAF MAV_4665|M.avium_104 QARELLAERGRVLGEAVALLRDMLNPDELVVGGQAFTEYPEAMEQVEAAF MAB_4059c|M.abscessus_ATCC_199 SARELLSERGRVLGQSVALLRDILNPDEVIVGGQAFTEYPEVMNDVETAF * *: :*.**** ::*****:****:::*******:** * : ** Mflv_0087|M.gilvum_PYR-GCK NERSALGHRDIRLTAFGNRVQEAGAGIVSLGGLYADPIAAMRRALARNER Mvan_0826|M.vanbaalenii_PYR-1 AARSVLPHRDIRVTAFGNRIQEAGAGIVSLGGLYADPIGAMRR--ARRPQ MSMEG_0932|M.smegmatis_MC2_155 AERSMLGPRDIRLTAFGNRVQEAGAGVVSLGGLYADPIGAMRR--AQTRR TH_0877|M.thermoresistible__bu TTRSVLPPLEIRTTAFGNRVQEAGAGVVSLGSLYADPIGAMRRALDAPRT Mb0495|M.bovis_AF2122/97 TAGSVLAPRDIRVTVFGNRVQEAGAGIVSLSGLYADPLGALRRSGALDAR Rv0485|M.tuberculosis_H37Rv TAGSVLAPRDIRVTVFGNRVQEAGAGIVSLSGLYADPLGALRRSGALDAR MMAR_0811|M.marinum_M TARSVLAPRDIRVTSFGNRVQEAGAGIVSLGGLYADPRGAMRRSGALNTR MUL_4555|M.ulcerans_Agy99 TARSVLAPRDIRVTSFGNRVQEAGAGIVSLGGLYADPRGAMRRSGALNTR MAV_4665|M.avium_104 AARSVLGPRDIRLTAFGNRVQEAGAGTVSLSGLYADPLSAMRRAGALDAR MAB_4059c|M.abscessus_ATCC_199 LDRSTLSKRDIRVTAFGNRVQEAGAGVVSLGGLFADPLGAMRRASARRGE * * :** * ****:****** ***..*:*** .*:** Mflv_0087|M.gilvum_PYR-GCK LGSASPAAV--- Mvan_0826|M.vanbaalenii_PYR-1 VSA--------- MSMEG_0932|M.smegmatis_MC2_155 AAAV-------- TH_0877|M.thermoresistible__bu SARVLTGQHATG Mb0495|M.bovis_AF2122/97 LQDTAPEALA-- Rv0485|M.tuberculosis_H37Rv LQDTAPEALA-- MMAR_0811|M.marinum_M LRQAEPEASA-- MUL_4555|M.ulcerans_Agy99 LRQAEPEASA-- MAV_4665|M.avium_104 LREVARDESSA- MAB_4059c|M.abscessus_ATCC_199 ASALA-------