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M. smegmatis MC2 155 MSMEG_0932 (-)

annotation: ROK family protein
coordinates: 1012561 - 1013760
length: 399

VAPSLKVPDAAAASVFNAVRLRGPIARDVIAQHTSLSIATVNRQVTALLEAGVLRERADLAVSGAIGRPR
VPVEVNHEPYLTLGVHIGAKTTAIVATDLLGRTLDVVETPTPTGTQAAALATLASSARRYLSRWHRRRPL
WVGVAAGGVVDSATGYLDHPRLGWADAPVGPVLAEALGLPVSMASHVDAMAGAELLLSGRRAENAGGASR
TSLYVYARETVGYALSIDGRVHSPASGPGTIAGLPARSELLGGTGQLESTVSDEAVLNAARRLRIVPAEG
PASTLPAVLRAARGGNEKAVELLADRARVLGEAVALLRDMLNPDELVVGGQAFTEYPEGMEAVEAAFAER
SMLGPRDIRLTAFGNRVQEAGAGVVSLGGLYADPIGAMRRAQTRRAAAV
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_0932--100% (399)ROK family protein
M. smegmatis MC2 155MSMEG_0316-1e-1325.06% (391) putative NagC regulator
M. smegmatis MC2 155MSMEG_6022-8e-1326.46% (393) xylose repressor, ROK-family protein transcriptional regulator

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0495-1e-16375.25% (396) transcriptional regulatory protein
M. gilvum PYR-GCKMflv_0087-0.083.25% (394) ROK family protein
M. tuberculosis H37RvRv0485-1e-16375.25% (396) transcriptional regulatory protein
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4059c-1e-16675.25% (396) hypothetical protein MAB_4059c
M. marinum MMMAR_0811-1e-16777.33% (397) transcriptional regulatory protein
M. avium 104MAV_4665-1e-16877.83% (397) ROK family protein
M. thermoresistible (build 8)TH_0877-1e-16876.98% (391) POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN
M. ulcerans Agy99MUL_4555-1e-16676.83% (397) transcriptional regulatory protein
M. vanbaalenii PYR-1Mvan_0826-1e-17178.57% (406) ROK family protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0087|M.gilvum_PYR-GCK          -MSTTTLAPRTRTTSAENAAAKRPAAGGRYPQALLHQIVAPSLCLPEAAA
Mvan_0826|M.vanbaalenii_PYR-1       -MSTSTLAQRPRAASVTRTG---PATGGRYPHALLHHIVAPALRVPEAAA
MSMEG_0932|M.smegmatis_MC2_155      --------------------------------------MAPSLKVPDAAA
TH_0877|M.thermoresistible__bu      VARTANTVSTPRTASSLLRPAGVTASRTRRPLVSRQRVVAPSLRVADAAA
Mb0495|M.bovis_AF2122/97            -----------MYSTNRTSQSLSRKPGRKHQLRSHRYVMPPSLHLSDSAA
Rv0485|M.tuberculosis_H37Rv         -----------MYSTNRTSQSLSRKPGRKHQLRSHRYVMPPSLHLSDSAA
MMAR_0811|M.marinum_M               -------------------------------------MVAPSLHLADSAA
MUL_4555|M.ulcerans_Agy99           -------------------------------------MVAPSLHLADSAA
MAV_4665|M.avium_104                ---------------------MGHAPGPKPHRAVRRQIVPPALHIPESAA
MAB_4059c|M.abscessus_ATCC_199      ------------------------MTAPVRRPVSRHQIHPPALYIGDSAA
                                                                           .*:* : ::**

Mflv_0087|M.gilvum_PYR-GCK          ASVFAAARQRGPIARDVIAQVTGLSIATVNRQVTALLDAGLLRERADLAV
Mvan_0826|M.vanbaalenii_PYR-1       AAVLAAARQRGPIARDVIAQVTGLSIATVNRQVTALLEVGLLRERADLAV
MSMEG_0932|M.smegmatis_MC2_155      ASVFNAVRLRGPIARDVIAQHTSLSIATVNRQVTALLEAGVLRERADLAV
TH_0877|M.thermoresistible__bu      ASVFEAARLRGPIARDAIAKATGLSIATVNRQVIALLEAGLLRERPDLAV
Mb0495|M.bovis_AF2122/97            ASVFRAVRLRGPVGRDVIAGSTSLSIATVNRQVIALLEAGLLRERADLAV
Rv0485|M.tuberculosis_H37Rv         ASVFRAVRLRGPVGRDVIAGSTSLSIATVNRQVIALLEAGLLRERADLAV
MMAR_0811|M.marinum_M               ASVFRAVRLRGPVGRDVIATTTSLSIATVNRQVIALLDAGLLRERADLAV
MUL_4555|M.ulcerans_Agy99           ASVFRAVRLRGPVGRDVIATTTSLSIATVNRQVIALLDAGLLWERADLAV
MAV_4665|M.avium_104                ASVFRAVRLRGPVGRDVIANVTSLSIATVNRQVIALLEAGLLRERADLAV
MAB_4059c|M.abscessus_ATCC_199      SSVFRAARVRGPVARDAIAQVTGLSIATVNRQVTALLDAGLLRERADLAV
                                    ::*: *.* ***:.**.**  *.********** ***:.*:* **.****

Mflv_0087|M.gilvum_PYR-GCK          SGAIGRPRVPVEVNHEPFLTLGIHIGARTTSIVAADLFGRTLDVVETPTP
Mvan_0826|M.vanbaalenii_PYR-1       SGAIGRPRVPVEVNHGPFLTLGIHIGARTTSIVATDLLGRTLDVVETATP
MSMEG_0932|M.smegmatis_MC2_155      SGAIGRPRVPVEVNHEPYLTLGVHIGAKTTAIVATDLLGRTLDVVETPTP
TH_0877|M.thermoresistible__bu      SGAIGRPRVPVEVDHDPYLTLGIHIGARTTSIAATDLFGRTLDVVETPTP
Mb0495|M.bovis_AF2122/97            SGAIGRPRVPVEVNHEPFVTLGIHIGARTTSIVATDLFGRTLDTVETPTP
Rv0485|M.tuberculosis_H37Rv         SGAIGRPRVPVEVNHEPFVTLGIHIGARTTSIVATDLFGRTLDTVETPTP
MMAR_0811|M.marinum_M               SGAIGRPRVPVEVNHEPFVTLGLHIGARTTSIVATDLLGRTLDTVETATP
MUL_4555|M.ulcerans_Agy99           SGAIGRPRVPVEVNHEPFVTLGLHIGARTTSIVATDLLGRTLDTVETATP
MAV_4665|M.avium_104                SGAIGRPRVPVEVNHEPFVTLGIHIGARTTSIVATDLFGRTLDTVETPTP
MAB_4059c|M.abscessus_ATCC_199      SGAIGRPRVPVELNHEPFLTLGIHIGARATSIVATDLFGRTLDVVETPTP
                                    ************::* *::***:****::*:*.*:**:*****.***.**

Mflv_0087|M.gilvum_PYR-GCK          RGPQAVALTAIAGSASRYLSR--------WHRRRPLWVGVATGGVVDSAT
Mvan_0826|M.vanbaalenii_PYR-1       RGPQAAALAAVAGSARRYLSRPPRAGGAPRRRRRPLWVGVATGGVVDSAT
MSMEG_0932|M.smegmatis_MC2_155      TGTQAAALATLASSARRYLSR--------WHRRRPLWVGVAAGGVVDSAT
TH_0877|M.thermoresistible__bu      RGAQPGAVASLAESARRYLSR--------WHRRRPLWVGVAAGGVFDVTT
Mb0495|M.bovis_AF2122/97            RNAAGAALTSLADSADRYLQR--------WRRRRALWVGVTLGGAVDSAT
Rv0485|M.tuberculosis_H37Rv         RNAAGAALTSLADSADRYLQR--------WRRRRALWVGVTLGGAVDSAT
MMAR_0811|M.marinum_M               RSSASSALASLADSAGRYLRR--------WHRRRALWVGVAIGGTVDDAS
MUL_4555|M.ulcerans_Agy99           RSSASSALASLADSAGRYLRR--------WHRRRALWVGVAIGGTVDDAS
MAV_4665|M.avium_104                RNPAGPALASLADSARRYLRR--------WHRRRPLWIGVAIGGTVDSAT
MAB_4059c|M.abscessus_ATCC_199      NGPQGAALASLAGSAQRYLAR--------WHRRRPLWVGVATGGVVDGPA
                                     ..   *::::* ** *** *         :***.**:**: **..* .:

Mflv_0087|M.gilvum_PYR-GCK          GYLDHPRLGWADAPVGPVLAETLGLPVSVASHVDAMAGAELLLGVRRRP-
Mvan_0826|M.vanbaalenii_PYR-1       GYVNHPRLGWSDAPVGTVLGEALGLPVSLASHVDAMAGAELLLGVRRQP-
MSMEG_0932|M.smegmatis_MC2_155      GYLDHPRLGWADAPVGPVLAEALGLPVSMASHVDAMAGAELLLSGRRAEN
TH_0877|M.thermoresistible__bu      GHLDHPLLGWTDAPVGPVLAETLGLPVSVAPHLDAMAAAELLLGRSRRR-
Mb0495|M.bovis_AF2122/97            GHVDHPRLGWRQAPVGPVLADALGLPVSVASHVDAMAGAELMLGMRRFAP
Rv0485|M.tuberculosis_H37Rv         GHVDHPRLGWRQAPVGPVLADALGLPVSVASHVDAMAGAELMLGMRRFAP
MMAR_0811|M.marinum_M               GHVDHQRLGWRQAPVGPALADALGLPVSVASHVDAMAGAELLLGTRRLAG
MUL_4555|M.ulcerans_Agy99           GHVDHQRLGWRHAPVGPALADALGLPVSVASHVDAMAGAELLLGTRRLAG
MAV_4665|M.avium_104                GQVDHPRLGWRQAPVGQVLADALGLPVSVASHVDAMAGAELLLGMRRFLP
MAB_4059c|M.abscessus_ATCC_199      GTVDHPRLGWTEAPVGRVFADTLGLPVSVASHVDAMAGAELLLGLRRFAA
                                    * ::*  *** .**** .:.::******:*.*:****.***:*.  *   

Mflv_0087|M.gilvum_PYR-GCK          --GKAATGLYVYARETVGYALSIGGRVHSPTSGPGTIASLPVRSELLGGT
Mvan_0826|M.vanbaalenii_PYR-1       --AKSTTSLYVYARETVGYALSIGGQVHSPSSGPGTIAALPAFSELLGGT
MSMEG_0932|M.smegmatis_MC2_155      AGGASRTSLYVYARETVGYALSIDGRVHSPASGPGTIAGLPARSELLGGT
TH_0877|M.thermoresistible__bu      ----GTTSLFMYARETVGYALSIAGRVHSPAAGPGTIAALPVNSDLLGGT
Mb0495|M.bovis_AF2122/97            ---SSSTSLYVYARETVGYALMIGGRVHCPASGPGTIAPLPVHSEMLGGT
Rv0485|M.tuberculosis_H37Rv         ---SSSTSLYVYARETVGYALMIGGRVHCPASGPGTIAPLPVHSEMLGGT
MMAR_0811|M.marinum_M               ---GSSTSLYVYARETVGYALVIDGRVHCPASGPGTIAGLPAHSELLGGT
MUL_4555|M.ulcerans_Agy99           ---GSSTSLYVYARETVGYALVIDGRVHCPASGPGTIAGLPAHSELLGGT
MAV_4665|M.avium_104                ---SSPTSLYVYARETVGYALVIGGRVHVPTSGPGTIATLPAHSELLGGT
MAB_4059c|M.abscessus_ATCC_199      ---RSLTSLYVYARETVGFALAIDGRVHSPSSGPGTIAALPVDSELLGGS
                                        . *.*::*******:** * *:** *::****** **. *::***:

Mflv_0087|M.gilvum_PYR-GCK          GQLESTVSDEAVLTAARRAGVVPADG-------PASTVTAVLRAARQGDE
Mvan_0826|M.vanbaalenii_PYR-1       GQLESTVSDEAVLTAARKAGIVAAEG-------PTSTVTAVLRAARQGNA
MSMEG_0932|M.smegmatis_MC2_155      GQLESTVSDEAVLNAARRLRIVPAEG-------PASTLPAVLRAARGGNE
TH_0877|M.thermoresistible__bu      GQLETTVSDQAVVTAARRLNVIPPEG-------PASTIAAVLRAAQRGDS
Mb0495|M.bovis_AF2122/97            GQLESTVSDEAVLAAARRLRIIPGIASRTRTGGSATAITDLLRVARAGNQ
Rv0485|M.tuberculosis_H37Rv         GQLESTVSDEAVLAAARRLRIIPGIASRTRTGGSATAITDLLRVARAGNQ
MMAR_0811|M.marinum_M               GQLESTVSDEAVLAAARRLRIIAATP-QARTNGSVTAMTDLLRVARAGNQ
MUL_4555|M.ulcerans_Agy99           GQLESTVSDEAVLAAARRLRIIAATP-QARTNGSITAMTDLLRVARAGNQ
MAV_4665|M.avium_104                GQLESTVSDEAVVAVARQLRILPFAP-ANRASGSAAGIADLLRVARAGNE
MAB_4059c|M.abscessus_ATCC_199      GKLETTVSDEAVLAAARKLRIVPAGD--------GVSVSAVYKAARGGNE
                                    *:**:****:**: .**:  ::.              :. : :.*: *: 

Mflv_0087|M.gilvum_PYR-GCK          HAVALIAERARVLGEAVALLRDMLNPDDLVVGGQAFTEYPEGMSIVEEAF
Mvan_0826|M.vanbaalenii_PYR-1       AAAALVAERARVLGEAVALLRDMLNPDDLVVGGQAFTEYPEGMPLVESAF
MSMEG_0932|M.smegmatis_MC2_155      KAVELLADRARVLGEAVALLRDMLNPDELVVGGQAFTEYPEGMEAVEAAF
TH_0877|M.thermoresistible__bu      TARELLDERARVLGESLALLRDMLNPDEVVVGGQAFTDYPAGMETLTAAF
Mb0495|M.bovis_AF2122/97            QAKELLAERARVLGGAVALLRDLLNPDEVVVGGQAFTEYPEAMEQVEAAF
Rv0485|M.tuberculosis_H37Rv         QAKELLAERARVLGGAVALLRDLLNPDEVVVGGQAFTEYPEAMEQVEAAF
MMAR_0811|M.marinum_M               QARELLAERARVLGETVALLRDVLNPDELVVGGQAFTEYPEGMRQVEEAF
MUL_4555|M.ulcerans_Agy99           QARELLAERARVLGETVALLRDVLNPDELVVGGQAFTEYPEGMRQVKEAF
MAV_4665|M.avium_104                QARELLAERGRVLGEAVALLRDMLNPDELVVGGQAFTEYPEAMEQVEAAF
MAB_4059c|M.abscessus_ATCC_199      SARELLSERGRVLGQSVALLRDILNPDEVIVGGQAFTEYPEVMNDVETAF
                                     *  *: :*.**** ::*****:****:::*******:**  *  :  **

Mflv_0087|M.gilvum_PYR-GCK          NERSALGHRDIRLTAFGNRVQEAGAGIVSLGGLYADPIAAMRRALARNER
Mvan_0826|M.vanbaalenii_PYR-1       AARSVLPHRDIRVTAFGNRIQEAGAGIVSLGGLYADPIGAMRR--ARRPQ
MSMEG_0932|M.smegmatis_MC2_155      AERSMLGPRDIRLTAFGNRVQEAGAGVVSLGGLYADPIGAMRR--AQTRR
TH_0877|M.thermoresistible__bu      TTRSVLPPLEIRTTAFGNRVQEAGAGVVSLGSLYADPIGAMRRALDAPRT
Mb0495|M.bovis_AF2122/97            TAGSVLAPRDIRVTVFGNRVQEAGAGIVSLSGLYADPLGALRRSGALDAR
Rv0485|M.tuberculosis_H37Rv         TAGSVLAPRDIRVTVFGNRVQEAGAGIVSLSGLYADPLGALRRSGALDAR
MMAR_0811|M.marinum_M               TARSVLAPRDIRVTSFGNRVQEAGAGIVSLGGLYADPRGAMRRSGALNTR
MUL_4555|M.ulcerans_Agy99           TARSVLAPRDIRVTSFGNRVQEAGAGIVSLGGLYADPRGAMRRSGALNTR
MAV_4665|M.avium_104                AARSVLGPRDIRLTAFGNRVQEAGAGTVSLSGLYADPLSAMRRAGALDAR
MAB_4059c|M.abscessus_ATCC_199      LDRSTLSKRDIRVTAFGNRVQEAGAGVVSLGGLFADPLGAMRRASARRGE
                                       * *   :** * ****:****** ***..*:*** .*:**       

Mflv_0087|M.gilvum_PYR-GCK          LGSASPAAV---
Mvan_0826|M.vanbaalenii_PYR-1       VSA---------
MSMEG_0932|M.smegmatis_MC2_155      AAAV--------
TH_0877|M.thermoresistible__bu      SARVLTGQHATG
Mb0495|M.bovis_AF2122/97            LQDTAPEALA--
Rv0485|M.tuberculosis_H37Rv         LQDTAPEALA--
MMAR_0811|M.marinum_M               LRQAEPEASA--
MUL_4555|M.ulcerans_Agy99           LRQAEPEASA--
MAV_4665|M.avium_104                LREVARDESSA-
MAB_4059c|M.abscessus_ATCC_199      ASALA-------