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M. smegmatis MC2 155 MSMEG_0684 (-)

annotation: aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
coordinates: 766670 - 768784
length: 704

TLREPRAIGQPVIRKESRAKVTGAAPYAFEHIVDNALYLHPVQATIARGRVVAMDVAAARALDGVRGILT
VFDAPELADTSDGEFAILQDDRVHFRGQIIGGVLAESAETAREAAALVRVEYLQEPHDTELRADHPGLYT
PDEVNGGEEPDTDDGDVEAALAQAAVTVDETYETPIEHNNPMEPHACIAQWNLGDSGKPAVVLYDSTQGV
HAVRKALAPIFGLEPEQIRVIAPHVGGGFGSKGAPHAHNVLAILAAQRSNGRPVKLALTRQQMFSLVGYR
TPTIQRIRLGADHDGRITALVHDVVEQTSAVKEFAEQTAITSRKMYSAASRRTTHKLAALDVAIPFWMRA
PGECPGTYAAEVAMDELAVACGLDPIELRVRNDPEVDPETGKPWSGRHLVDCLRLGADRFGWAARDPRPA
ARRDGEWLIGTGVAAATYPGKAMPGNSARITYAAEGRYTVQIGAADIGTGTWTTLSQIAADALACDLAAV
DLQIGDTDLPEASVAGGSSGITSWGSAIVAAARQFRADHGDPPAVGATTVAQSPENPDADGVTMQSFGAH
FVEAHVNADTGEIRVPRMLGVFSVGRVINARTLRSQLIGGMTMGLSMALHEESVRDPRFGHVVTQDLATY
HISAHADVADIDAIWLDEADEYLNPMGSRGAGEIGIVGSASAVVNAVYHATGVRVRNLPVTVDKVLAGLP
KLV*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_0684--100% (704)aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
M. smegmatis MC2 155MSMEG_0870-e-11536.94% (739) oxidoreductase
M. smegmatis MC2 155MSMEG_1291-2e-6228.49% (744) putative oxidoreductase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0380c-2e-4426.58% (775) carbon monoxyde dehydrogenase large subunit
M. gilvum PYR-GCKMflv_0284-0.078.03% (701) aldehyde oxidase and xanthine dehydrogenase, molybdopterin
M. tuberculosis H37RvRv0373c-4e-4426.58% (775) carbon monoxyde dehydrogenase large subunit
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2925c-1e-5629.05% (747) xanthine dehydrogenase family protein
M. marinum MMMAR_0080coxL_21e-11337.41% (703) carbon monoxyde dehydrogenase (large chain), CoxL_2
M. avium 104-----
M. thermoresistible (build 8)TH_0176-2e-4426.88% (770) PROBABLE CARBON MONOXYDE DEHYDROGENASE (LARGE CHAIN)
M. ulcerans Agy99MUL_4580coxL_11e-10634.64% (739) carbon monoxyde dehydrogenase (large chain), CoxL_1
M. vanbaalenii PYR-1Mvan_2075-1e-11537.15% (724) aldehyde oxidase and xanthine dehydrogenase, molybdopterin

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_0684|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_0284|M.gilvum_PYR-GCK          --------------------------------------------------
MUL_4580|M.ulcerans_Agy99           --------------------------------------------------
Mvan_2075|M.vanbaalenii_PYR-1       --------------------------------------------------
MMAR_0080|M.marinum_M               --------------------------------------------------
Mb0380c|M.bovis_AF2122/97           --------------------------------------------------
Rv0373c|M.tuberculosis_H37Rv        --------------------------------------------------
TH_0176|M.thermoresistible__bu      --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199      MKVNGKLIDASPRPGQCLRTFLREHGHVEVKKGCDAGDCGACTVLVDGAS
                                                                                      

MSMEG_0684|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_0284|M.gilvum_PYR-GCK          --------------------------------------------------
MUL_4580|M.ulcerans_Agy99           --------------------------------------------------
Mvan_2075|M.vanbaalenii_PYR-1       --------------------------------------------------
MMAR_0080|M.marinum_M               --------------------------------------------------
Mb0380c|M.bovis_AF2122/97           --------------------------------------------------
Rv0373c|M.tuberculosis_H37Rv        --------------------------------------------------
TH_0176|M.thermoresistible__bu      --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199      QHSCIVPAHRVTDAEIHTVRSLAGEHDLHPMQRGFIDHAGFQCGFCTAGM
                                                                                      

MSMEG_0684|M.smegmatis_MC2_155      ---------------------------------MTLREPRAIGQPVIRKE
Mflv_0284|M.gilvum_PYR-GCK          ---------------------------------MTMLEPRAIGAPTARRD
MUL_4580|M.ulcerans_Agy99           ------------------------------MTHAFSAAGGISGQPINRVD
Mvan_2075|M.vanbaalenii_PYR-1       ----------------------------------MVAS---VGLPVNRVE
MMAR_0080|M.marinum_M               ---------------------------------MTTAPATRGAMRFARVE
Mb0380c|M.bovis_AF2122/97           ------------------MTTIESRPPS-PEDLADNAQQPCGHGRMMRKE
Rv0373c|M.tuberculosis_H37Rv        ------------------MTTIESRPPS-PEDLADNAQQPCGHGRMMRKE
TH_0176|M.thermoresistible__bu      ------------------MTTLESNPAARPDDFENNDQKPCGHGRMLRKE
MAB_2925c|M.abscessus_ATCC_199      VLTAATLTGDQTEDLGNALKGNLCRCTGYRPIRDAVCGVVPPRGSVSAPA
                                                                                      

MSMEG_0684|M.smegmatis_MC2_155      SRAKVTGAAPYAFEHIVDNALYLHPVQATIARGRVVAMDVAAARA----L
Mflv_0284|M.gilvum_PYR-GCK          GQAKVTGAAAYAYEQQVDSPAYLHPVQATIARGRVIAMDTNLARA----V
MUL_4580|M.ulcerans_Agy99           GPLKVTGKARYAADHPIPGLVYAALVCSTVARGAVDHIATGAAMR----Q
Mvan_2075|M.vanbaalenii_PYR-1       GVDKVTGKARYSADTQVAGVAYAALVQAQIPHGRVTAESVDAAAATASAA
MMAR_0080|M.marinum_M               AYSKITGTARYAADHRPEGLLYAVLVGAPVAAGRLKAVDADAALG----S
Mb0380c|M.bovis_AF2122/97           DPRFIRGRGTYVDDVALPGMLHLAILRSPYAHARIVRIDVTAAQA----H
Rv0373c|M.tuberculosis_H37Rv        DPRFIRGRGTYVDDVALPGMLHLAILRSPYAHARIVRIDVTAAQA----H
TH_0176|M.thermoresistible__bu      DPRFIRGRGRYVDDVQLPGMLHLAILRSPYAHARIAGIDTSAAQA----H
MAB_2925c|M.abscessus_ATCC_199      AARVVTGTEPYTMDELPAGVGHVAVLGSPHPSARITRIDTDRARL----L
                                        : *   *  :    .  :   : :  . . :    .  *       

MSMEG_0684|M.smegmatis_MC2_155      DGVRGILTVFDAPELADTSDG--------EFAILQDDRVHFRGQIIGGVL
Mflv_0284|M.gilvum_PYR-GCK          DGVLDILTVSDAPKLADASDG--------ELAILQDATVHFRGQLIGGVV
MUL_4580|M.ulcerans_Agy99           PGVLAVLTDFTG-----------------VRLPFGTGQVFFFGQPIAVVV
Mvan_2075|M.vanbaalenii_PYR-1       PGVLYVLTPTNCPPLQVLPKELTWDLPLERRPPLSDLTVQHVGQHMALVV
MMAR_0080|M.marinum_M               PGVVAVLIADDLPDFPLLSPP-----SAVRRMPLMNNEIHYEGQAVAIVI
Mb0380c|M.bovis_AF2122/97           PKVKAVVTGADLAAKGLAWMP---TLANDVQAVLATDKTRFQGQEVASVV
Rv0373c|M.tuberculosis_H37Rv        PKVKAVVTGADLAAKGLAWMP---TLANDVQAVLATDKTRFQGQEVAFVV
TH_0176|M.thermoresistible__bu      PKVKAVVTGADLAEKGLAWMP---TLSNDVQAVLATDKVRFQGQEVAFVV
MAB_2925c|M.abscessus_ATCC_199      PGVRAVLCYRDDPGVPFSTARHHERTDDPDDTLVFDRVLRFAGQRVAAVV
                                      *  ::                          .      . ** :. *:

MSMEG_0684|M.smegmatis_MC2_155      AESAETAREAAALVRVEYLQEPHDTELRADHPGLYTPDEVNGGEEPDTDD
Mflv_0284|M.gilvum_PYR-GCK          AETAEIAREAAALVHVEYQEKEHDAALRADHPGLYTPESVNPSYPPDSDQ
MUL_4580|M.ulcerans_Agy99           ATTHEAAAHAVSLVDVSYSTWPQLTDIDAPQAVGYPGRLIADYVRG---T
Mvan_2075|M.vanbaalenii_PYR-1       ADSPENAVHAASLMDFDYIAAPAHLDATEVVSGGGAADDVDELIRHGAYR
MMAR_0080|M.marinum_M               AESIEAAEAARALVVVDCERTNAVVLGSGTREP-ADGEYSDPFDKG---D
Mb0380c|M.bovis_AF2122/97           AEDRYSARDACELVDVDYEPRDPVVDARTALDPSAPVIRTDLEGKSDNHI
Rv0373c|M.tuberculosis_H37Rv        AEDRYSARDACELVDVDYEPRDPVVDARTALDPSAPVIRTDLEGKSDNHI
TH_0176|M.thermoresistible__bu      AEDHYSARDALELIDVDYDPLDPVVDVRRALEPDAPVIRTDLDGKTDNHC
MAB_2925c|M.abscessus_ATCC_199      ADTPAIAHRALEHIDVEYEVLPAVFDPEMAQLPGAHLVHGDKGLGARIAD
                                    *     *  *   : ..                                 

MSMEG_0684|M.smegmatis_MC2_155      GDVEAALA----------------QAAVTVDETYETPIEHNNPMEPHACI
Mflv_0284|M.gilvum_PYR-GCK          GDVESAFP----------------AAEFTVDQTYRTPTEHNNPMEPHACV
MUL_4580|M.ulcerans_Agy99           PDQVMIR-----------------AAGIS-DLNFSIARNNHNAVELPATI
Mvan_2075|M.vanbaalenii_PYR-1       PDHFVKLTDEKLQ---DFRGPRGEPPGIKVDQTYRTAVNAHYPIELSATV
MMAR_0080|M.marinum_M               FDTAWSN------------------AAIRVERTYLQPPRHHHAMETSGTV
Mb0380c|M.bovis_AF2122/97           FDWETGDAAAT--------EAVFAKADVVVQQEIVYPRVHPAPMETCGAV
Rv0373c|M.tuberculosis_H37Rv        FDWETGDAAAT--------EAVFAKADVVVQQEIVYPRVHPAPMETCGAV
TH_0176|M.thermoresistible__bu      FDWETGDPAAT--------EAAFAKADVVVEQEIVYPRVHPAPMETCGAV
MAB_2925c|M.abscessus_ATCC_199      PARNLVAEVHGEVGDVAAALARARESGAVVTGSWQTARVQHVHLETHGSV
                                                             .          .      :*  . :

MSMEG_0684|M.smegmatis_MC2_155      AQWNLGDSGKPAVVLYDSTQGVHAVRKALAPIFGLEPEQIRVIAPHVGGG
Mflv_0284|M.gilvum_PYR-GCK          AQWTVRD-GTPAVTMYDSTQGVHVVRKTLAPIFGLEPEQMRVVAPHVGGG
MUL_4580|M.ulcerans_Agy99           AKWDGDR-----LTLWDKVQHINGARRSYARAFGMSEERVRLISPFVGGA
Mvan_2075|M.vanbaalenii_PYR-1       AQWDDGH-----LTVHDCTRWITGERRVLAAYLNIPEERIRVVSPLVGGA
MMAR_0080|M.marinum_M               AQWDEDQ-----LTLWDAVQASATVPPVIATALGIDAHRIRIVAPHIGGG
Mb0380c|M.bovis_AF2122/97           ADLDPVTG---KLTLWTTSQAPHAHRTLYALVAGLPEHKIRVISPDIGGG
Rv0373c|M.tuberculosis_H37Rv        ADLDPVTG---KLTLWTTSQAPHAHRTLYALVAGLPEHKIRVISPDIGGG
TH_0176|M.thermoresistible__bu      ADLDPVTG---KLTLWSTSQAPHAHRTLYALVAGLPEHKIRVIAPDIGGG
MAB_2925c|M.abscessus_ATCC_199      GWQDERGR----YVLRTSSQVPFLVRDELCHVFGLAREQVRVFAPRVGGG
                                    .            .:    :         .   .:  .::*:.:* :**.

MSMEG_0684|M.smegmatis_MC2_155      FGSKGAPHAHNVLAILAAQRSNGRPVKLALTRQQMFSLVGYRTPTIQRIR
Mflv_0284|M.gilvum_PYR-GCK          FGSKGAPHAHDVLTVMAAQRAGGRPVKLALTRQQMFSLVGYRTPTIQRVR
MUL_4580|M.ulcerans_Agy99           FGSAGRMWPHQLLTVFAARRMQ-LPVKLVLTRKQMYSSVGFRPTSRQRMA
Mvan_2075|M.vanbaalenii_PYR-1       FGSKSFLWMHVVLCAVAAREVG-RPVKLVLTRDQMFTSTGHRPRTEQQVA
MMAR_0080|M.marinum_M               FGSKSFVWPHQTLAAAAARVTG-RPVKLHLRRADQFSSVGYQPWMEQTMR
Mb0380c|M.bovis_AF2122/97           FGNKVPIYPGYVCAIVASLLLD-KPVKWMEDRSENLTSTGFARDYIMVGE
Rv0373c|M.tuberculosis_H37Rv        FGNKVPIYPGYVCAIVASLLLD-KPVKWMEDRSENLTSTGFARDYIMVGE
TH_0176|M.thermoresistible__bu      FGNKVPIYPGYVCAIVGSLLLG-KPVKWVEDRSENLTSTGFARDYIMVGE
MAB_2925c|M.abscessus_ATCC_199      FGAKQEMLT-EDLVLLAVRVTG-APVVYEFTRSDQFTIAPCRHPMRVNVT
                                    **              .       **     * :  : .           

MSMEG_0684|M.smegmatis_MC2_155      LGADHDGRITALVHDVVEQTSAVKEFAEQTAITSRKMYSAASRRTTHKLA
Mflv_0284|M.gilvum_PYR-GCK          LGADRDGRLTALVHDAIGQTATVKEFAEQTAVTSRKMYAAANRRTSHRLA
MUL_4580|M.ulcerans_Agy99           IGADPSGRLMAMIHEGRTETAQYGIYEDGIVRSPQLTYQVPNMSSTYRVV
Mvan_2075|M.vanbaalenii_PYR-1       LVADAAGTIVSTEHHTLTETSTVAHFCEPAGVSSRILYQSPRLAVTHTVA
MMAR_0080|M.marinum_M               LAADRTGRLIGIEHVAVNNTGMVDNYVEPATTATKGLYAADAIRTRQFVE
Mb0380c|M.bovis_AF2122/97           IAANRDGKILAIRSNVLADHGAFNAQAAPAKYP-AGFFGVFTGSYDIEAA
Rv0373c|M.tuberculosis_H37Rv        IAANRDGKILAIRSNVLADHGAFNAQAAPAKYP-AGFFGVFTGSYDIEAA
TH_0176|M.thermoresistible__bu      IAATRDGRILAIRSHVLADHGAFNGTAAPVKYP-AGFFGVFTGSYDLEAA
MAB_2925c|M.abscessus_ATCC_199      AAADGDGVLTALAVDVLSDAGAYGNHSVGVMFHGCNESMAQYRCANKRVD
                                      *   * : .       : .                             

MSMEG_0684|M.smegmatis_MC2_155      ALDVAIPFWMRAPG---------ECPGTYAAEVAMDELAVACGLDPIELR
Mflv_0284|M.gilvum_PYR-GCK          ALDVPVPFWMRAPG---------ECPGTYAAEVAMDELAVAAGIDPIQLR
MUL_4580|M.ulcerans_Agy99           PLDINLPWFMRGPG---------AVTGTFALESTMDDLAHRLGIDPIELR
Mvan_2075|M.vanbaalenii_PYR-1       RIHAPTPCFMRGPG---------EAPGLFALEMAMDELAYALGRDPLALR
MMAR_0080|M.marinum_M               RVNLNVPTPMRAPL---------EGPGMWALESAMNELADEAGMDPLDLR
Mb0380c|M.bovis_AF2122/97           YCHMTAVYTNKAPGGVAYACSFRITEAVYFVERLVDCLAFELKMDPAELR
Rv0373c|M.tuberculosis_H37Rv        YCHMTAVYTNKAPGGVAYACSFRITEAVYFVERLVDCLAFELKMDPAELR
TH_0176|M.thermoresistible__bu      YCHMTAVYTNKAPGGVAYACSFRITEAVYLVERLVDCLAHELEMDPAELR
MAB_2925c|M.abscessus_ATCC_199      AQAVYTNNIPSGAFRG-----YGLGQVLFGIESALDELARNLGIDPFEFR
                                               ..               :  *  :: **     **  :*

MSMEG_0684|M.smegmatis_MC2_155      VRNDPEVD--------PETGKPWSGRHLVDCLRLGADRFGWAARD-PRPA
Mflv_0284|M.gilvum_PYR-GCK          IRNDPPTD--------PETGKPWSGRHLVECLEVGAERFDWSSRD-PEPG
MUL_4580|M.ulcerans_Agy99           LRNEPRID--------QINGLPFSTRRLVDCIKQGSTDFGWHRRN-SIPG
Mvan_2075|M.vanbaalenii_PYR-1       MDNLADVD--------QTDGRPWSSAHLARCYTTGARRFGWDRRP-LQSR
MMAR_0080|M.marinum_M               LANYAENS--------PADGRPWSSNRLREAYAEGARRYRWRERY-ERPR
Mb0380c|M.bovis_AF2122/97           LRNLLRPNQ---FPYQSKTGWVYDSGDYETTMRKAMNMIGYEALR-AEQK
Rv0373c|M.tuberculosis_H37Rv        LRNLLRPNQ---FPYQSKTGWVYDSGDYETTMRKAMNMIGYEALR-AEQK
TH_0176|M.thermoresistible__bu      LRNLLKPDQ---FPYTSKTGWVYDSGDYETTMRKAMAMVGYDELR-AEQA
MAB_2925c|M.abscessus_ATCC_199      RRNVIVPGDSFVSWEVEEDDLAFGSYGLDQCLDLAQDALARGAADPARNG
                                      *    .           .  :.          .               

MSMEG_0684|M.smegmatis_MC2_155      ARRDGEWLIGTGVAAATYPGKAMPG-----------NSARITYAAEGRYT
Mflv_0284|M.gilvum_PYR-GCK          TRVLGDWLVGTGVASATYPGMAMPG-----------NAARITYSAEGHYD
MUL_4580|M.ulcerans_Agy99           ANRDGDSFVGIGMATAAYFTYRSK------------CAAIARISADGTAE
Mvan_2075|M.vanbaalenii_PYR-1       SLQRNGIRVGWGMATATYPGRRMP------------AACRVETDADGHVR
MMAR_0080|M.marinum_M               --AEGPWAIGHGMATCTMGSFRFP------------SQARVRLRDDGTAV
Mb0380c|M.bovis_AF2122/97           QRRARGELMGIGMSFFTEAVGAGPRKDMDILGLGMADGCELRVHPTGKAV
Rv0373c|M.tuberculosis_H37Rv        QRRARGELMGIGMSFFTEAVGAGPRKDMDILGLGMADGCELRVHPTGKAV
TH_0176|M.thermoresistible__bu      ERRRRGELMGIGMSFFTEAVGAGPRKDMDILGLGMADGCELRVHPTGKAV
MAB_2925c|M.abscessus_ATCC_199      SDLPAGWKVGEGMAIAMIATVPPRG---------HVADARAELDARGRYR
                                            :* *::                        .       *   

MSMEG_0684|M.smegmatis_MC2_155      VQIGAADIGTGTWTTLSQIAADALACDLAAVDLQIGDTDLPEASV-AGGS
Mflv_0284|M.gilvum_PYR-GCK          VHIGAADIGTGTWTTLSQIAADALDCDLAAITLQIGDTDLPAASV-AGGS
MUL_4580|M.ulcerans_Agy99           VCSAASDMGPGTYTSMTQIAADALGLPLQRVRFSLGDSRFPPAPA-HSAS
Mvan_2075|M.vanbaalenii_PYR-1       FSAATHEIGTGVRTVMTQLAADTTGLPLSQVSFESGDSSFPDAPY-SGAS
MMAR_0080|M.marinum_M               VEANVHDIGTGVQTILCQIAAAELGISSDRVEILWGDTDLPTAGP-AYGS
Mb0380c|M.bovis_AF2122/97           LRLSVQTQGQGHETTFAQIVAEELGIAPDDIEVVHGDTDQTPFGLGTYGS
Rv0373c|M.tuberculosis_H37Rv        LRLSVQTQGQGHETTFAQIVAEELGIAPDDIEVVHGDTDQTPFGLGTYGS
TH_0176|M.thermoresistible__bu      VRLSVQTQGQGHETTFAQIVAEELGIPPDDIEVVHGDTDQTPFGLGTYGS
MAB_2925c|M.abscessus_ATCC_199      ISVGSAEFGNGTTTVHAQLAAGVLGCAPDQVYIHQADTDAVSHDTGAFGS
                                    .       * *  *   *:.*         : .  .*:          .*

MSMEG_0684|M.smegmatis_MC2_155      SGITSWGSAIVAAARQFRA-------------------DHGDPPAVG---
Mflv_0284|M.gilvum_PYR-GCK          SGMTSWGTTIVLAAQQFRR-------------------DHGNPPVIG---
MUL_4580|M.ulcerans_Agy99           RTTASVGSAVFTVANMLHDKFIRAAV--TDPQSPLAGLRPEDVMVTNGHM
Mvan_2075|M.vanbaalenii_PYR-1       QTSASVGSAVFAAAQEWRG-------------------RADALPAT----
MMAR_0080|M.marinum_M               STTMSVGSAVAAAARHVVN--------------QLAALGIDDPAATG---
Mb0380c|M.bovis_AF2122/97           RSTPVSGGAAALVARKVRDKAKIIASGMLEVSVADLQWEKGKFHVKGDPS
Rv0373c|M.tuberculosis_H37Rv        RSTPVSGGAAALVARKVRDKAKIIASGMLEVSVADLQWEKGKFHVKGDPS
TH_0176|M.thermoresistible__bu      RSTPVSGAAAALVARKVRDKAKIIASGMLEASIADLEWEKGSFRVKGDPS
MAB_2925c|M.abscessus_ATCC_199      AGTTVAGLAVYRAAELLRDQIIRFAATKLAVPQSRCVLEPDGVRAGADLL
                                          * :   .*.                             .     

MSMEG_0684|M.smegmatis_MC2_155      --------------------------ATTVAQSPENPDADGVTMQSFGAH
Mflv_0284|M.gilvum_PYR-GCK          --------------------------ATTVTEAPD-PENDEVTVQSFGAH
MUL_4580|M.ulcerans_Agy99           FSTVATDGPARGESYQDLLRRRGWPALESEHTWTPDDAGKRYSTYAYGAV
Mvan_2075|M.vanbaalenii_PYR-1       -----ADGPGR-------------AAALSFTTASGPGPDVDTVSRSFGAH
MMAR_0080|M.marinum_M               --IAEVVGEGR--------------FSTPGGGTNLDGEGTPFAIRAWGAV
Mb0380c|M.bovis_AF2122/97           AAVTIADIAMRAHG------AGDLPEGIEGGLDAEVCYNPSNLTYPYGAY
Rv0373c|M.tuberculosis_H37Rv        AAVTIADIAMRAHG------AGDLPEGIEGGLDAEVCYNPSNLTYPYGAY
TH_0176|M.thermoresistible__bu      ASVTIQDIAMRAHG------AGDLPDGIEGGLDAQICYNPSNLTYPYGAY
MAB_2925c|M.abscessus_ATCC_199      G-------------------LTEIAASAPEPLSAVGHHEGTPRSVAFNVQ
                                                                                 .:.. 

MSMEG_0684|M.smegmatis_MC2_155      FVEAHVNADTGEIRVPRMLGVFSVGRVINARTLRSQLIGGMTMGLSMALH
Mflv_0284|M.gilvum_PYR-GCK          FVEAHVNRHTGEIRVPRMLGVFSIGRAINPRTLRSQLIGGMTMGLSMALH
MUL_4580|M.ulcerans_Agy99           FAEVAIDALLPTVRIRRIYACYDAGRVINPKLAHSQAIGGMIGGIGMALL
Mvan_2075|M.vanbaalenii_PYR-1       FCEVEVDEQIGRATVTRWVAVMDCGRVLNPKLATNQVMGGILFGLGMALM
MMAR_0080|M.marinum_M               FVEVGVDRDLGLIRLRHAVGVYSAGRILNPVTARAQMIGGIIWGWGKATL
Mb0380c|M.bovis_AF2122/97           FCVVDIDPGTAVVKVRRFLAVDDCGTRINPMIIEGQVHGGIVDGIGMALM
Rv0373c|M.tuberculosis_H37Rv        FCVVDIDPGTAVVKVRRFLAVDDCGTRINPMIIEGQVHGGIVDGIGMALM
TH_0176|M.thermoresistible__bu      FCVVDVDPGTAVVKVRRFLAVDDCGTRINPMIIEGQVHGGIVDGIGMALM
MAB_2925c|M.abscessus_ATCC_199      AFRVAVRPQTGTVRILQSVQTADAGVVVNPQQCRGQVEGGVAQAIGSALY
                                       . :        : :     . *  :*.     *  **:  . . *  

MSMEG_0684|M.smegmatis_MC2_155      EESVRDPRFGHVVTQDLATYHISAHADVA-DIDAIWLDEADEYLNPMGSR
Mflv_0284|M.gilvum_PYR-GCK          EESVRDPRFGHVVTQDFATYHISSHADVV-DIDAIWLDEVDEHLNPMGSR
MUL_4580|M.ulcerans_Agy99           EGTELDYRDGRVVNANISDYLVPINADVP-VLDASFLPAQDTIADPIGVK
Mvan_2075|M.vanbaalenii_PYR-1       EQVPHDPHTGRLLG----EYYVPTHADRP-AFDISFVDSSDYGLDPIGVR
MMAR_0080|M.marinum_M               EASTQEPTYGRWLAKNLSNVALPVNADIPAAIDVSFIDEFDSAASLIGAR
Mb0380c|M.bovis_AF2122/97           EMIAFD-EDGNCLGGSLMDYLIPTALEVP-HLETGHTVTP-SPHHPIGAK
Rv0373c|M.tuberculosis_H37Rv        EMIAFD-EDGNCLGGSLMDYLIPTALEVP-HLETGHTVTP-SPHHPIGAK
TH_0176|M.thermoresistible__bu      QMIGFD-EDGNCLGGSLMDYLIPTAMEVP-TLETGFTVTP-SPHHPIGAK
MAB_2925c|M.abscessus_ATCC_199      EEILVH--DGFVSTTALRNYHIPRLVDVP--DTEVYFADTYDTFGPLGAK
                                    :    .   *           :.   :                   :* :

MSMEG_0684|M.smegmatis_MC2_155      GAGEIGIVGSASAVVNAVYHATG---VRVRNLPVTVDKVLAGLPKLV---
Mflv_0284|M.gilvum_PYR-GCK          GAGEIGIVGSAAAVVNAVYHATG---IRVRDLPVTLDKVLAGLP------
MUL_4580|M.ulcerans_Agy99           GLGELVIIAVPAAIANAVFNATG---KRVTDLPIRVEQLL----------
Mvan_2075|M.vanbaalenii_PYR-1       GIGEIGVCGVAGAIASAIHHATG---KWLRQLPITLEALLGPRDDDRED-
MMAR_0080|M.marinum_M               GIGELGATGVDAAVAAAVYDAVG---VRVRELPILPWQVLS---------
Mb0380c|M.bovis_AF2122/97           GIGESATVGSPPAVVNAVVDALAPFGVRHADMPLTPSRVWEAMQGRATPP
Rv0373c|M.tuberculosis_H37Rv        GIGESATVGSPPAVVNAVVDALAPFGVRHADMPLTPSRVWEAMQGRATPP
TH_0176|M.thermoresistible__bu      GIGESATVGSPPAVVNAVVDALAPFGVRHVDMPLTPSRVWEAMQGRAQPS
MAB_2925c|M.abscessus_ATCC_199      SMSESPYNPVAPALANAIRDAVG---VRVYRLPMNAARVWRVINDSGGGE
                                    . .*        *:. *: .* .        :*:    :           

MSMEG_0684|M.smegmatis_MC2_155      --
Mflv_0284|M.gilvum_PYR-GCK          --
MUL_4580|M.ulcerans_Agy99           --
Mvan_2075|M.vanbaalenii_PYR-1       --
MMAR_0080|M.marinum_M               --
Mb0380c|M.bovis_AF2122/97           I-
Rv0373c|M.tuberculosis_H37Rv        I-
TH_0176|M.thermoresistible__bu      I-
MAB_2925c|M.abscessus_ATCC_199      SS