For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. smegmatis MC2 155 MSMEG_0288 (-)

annotation: FAD dependent oxidoreductase, putative
coordinates: 318960 - 320069
length: 369

VTIIGGGILGTAHAVEAVRRGHRVVHLEREAEARGATVRNFGLVWISGRSTAELDATLRSRELWEKLAVD
VPGIGFRPAGSITLVRTPAELAVAQEAATRSDAGHRGFTLLEPDEVRELNPALRGRFLGGLHCALDAAVE
SRQALPAIREHLTASGRYEFVAGVEARGVENRTVRDDRGNRHESDIVLVCAGAAHGGLVRDLAGELPVRR
VRLQMMQTEPLGERLTTAIADADSFRYYPGFAGPALNTLRDNQPQHRVADGQHMQLLCVQRLHGGLTIGD
THEYTEPFGFDVHEEPYTYLLDVVEEFLGRKLPPIRQRWAGVYSQCLDPEQLVCRTAPEDDIWVITGPGG
RGMTLGPAIAEQTADMIGL
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_0288--100% (369)FAD dependent oxidoreductase, putative

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCKMflv_3080-1e-0928.69% (244) FAD dependent oxidoreductase
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_1499-1e-13865.15% (373) putative FAD dependent oxidoreductase
M. marinum MMMAR_4421solA2e-0524.68% (389) dehydrogenase
M. avium 104MAV_0142-2e-0527.04% (196) FAD dependent oxidoreductase, putative
M. thermoresistible (build 8)TH_0796-1e-7970.20% (198) FAD dependent oxidoreductase, putative
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_0054-1e-15772.63% (369) FAD dependent oxidoreductase

CLUSTAL 2.0.9 multiple sequence alignment


MAB_1499|M.abscessus_ATCC_1997      -----MRVIVVGGGILGTAHAWAAVERGHEVVHLEREV---EARGATVRN
Mvan_0054|M.vanbaalenii_PYR-1       -----MQVTIIGAGILGTAHAWHAVRRGHHVIHLEREV---EARGATVRN
MSMEG_0288|M.smegmatis_MC2_155      -------MTIIGGGILGTAHAVEAVRRGHRVVHLEREA---EARGATVRN
TH_0796|M.thermoresistible__bu      -------VIIIGGGILGTAHAVEAVRRGHQVVQLEREG---EARGATVRN
MMAR_4421|M.marinum_M               MATTGYDVIVIGLGGMGSAAAYHLAARGRRVLGLERHQ---PAHDKGSSH
Mflv_3080|M.gilvum_PYR-GCK          -MPRTPRVVVIGAGIVGTSLADELTARGWTDVTVVDRGPLFATGGSTSHA
MAV_0142|M.avium_104                ------MIVVIGAGVCGLAAAHELSRRGHDDVVVLEKG-----QPFGEQS
                                           : ::* *  * : *     **   : :  .             

MAB_1499|M.abscessus_ATCC_1997      FGLVWVSG---RSALELKIAQRSRDLWQGIAKLVPG-IGFRQMGSFTLLR
Mvan_0054|M.vanbaalenii_PYR-1       FGLVWVSG---RASGELEASLRSRALWEEIGAEVPA-IGFRPCGSLTLLR
MSMEG_0288|M.smegmatis_MC2_155      FGLVWISG---RSTAELDATLRSRELWEKLAVDVPG-IGFRPAGSITLVR
TH_0796|M.thermoresistible__bu      FGLVWVSG---RAPAELDTALRARELWERLGAAIPG-IGFRPAGSLTLLK
MMAR_4421|M.marinum_M               GGSRIIRQSYFEDPGYVPLLLRSYELWERLAIDAQS-DIYRLTG--GLFI
Mflv_3080|M.gilvum_PYR-GCK          PGLVFQTN-----PSKTMTVFARYTVEKFAALQHPGGWAFNPVGGLEVAT
MAV_0142|M.avium_104                AGLARIFRIAHQREALCRLAFAARAGWQRWEAEFGV---GRLLGSEGFIA
                                     *                         :            .  *   .  

MAB_1499|M.abscessus_ATCC_1997      THEEVAVAEEVMARSDADERGFALLEPGAVQRQNPALRG-KFLAGLHCAR
Mvan_0054|M.vanbaalenii_PYR-1       TPAEVAVAEEVCGRADAASRGFRLLEPVEAREINPVLRG-KFLAALHCDR
MSMEG_0288|M.smegmatis_MC2_155      TPAELAVAQEAATRSDAGHRGFTLLEPDEVRELNPALRG-RFLGGLHCAL
TH_0796|M.thermoresistible__bu      TLDEVAVAEQAAARADAGRRGFTVVDAEQARRLNPALRG-DFLAALHCSR
MMAR_4421|M.marinum_M               GPPDCATVAGSLRASREWDLPHEVLDAPQIAARFPNFTP-QPTDIALYEA
Mflv_3080|M.gilvum_PYR-GCK          TPERMADLHRKAGWAQSWGIDGRLLTPSECVQLHPLVDRDRILGGFHTPA
MAV_0142|M.avium_104                AG---AAADGVAQAMKRAGAAFSRLDRDGIAERIPFADV-PWETGIFDPL
                                         *                  :         *               

MAB_1499|M.abscessus_ATCC_1997      DAAVESRVALPAMRLHLKTNGCYSFVAGREVRAIDTSSAGVSVRTDDG-E
Mvan_0054|M.vanbaalenii_PYR-1       DGAVESRQALPAIRAVLDATGRYTFVPGTEARAVD----GTRVHDDRG-N
MSMEG_0288|M.smegmatis_MC2_155      DAAVESRQALPAIREHLTASGRYEFVAGVEARGVEN----RTVRDDRG-N
TH_0796|M.thermoresistible__bu      DAAVESRRAMPAIRAHLAGTGRYTFRPGTEARSVS----GPSVRDDRG-G
MMAR_4421|M.marinum_M               KAGLAR--PELTVRAHLELAKRSGATLQFEEPVLNWTTTASGVRVTTGRD
Mflv_3080|M.gilvum_PYR-GCK          DGLAKALRAAEAQARRAEARGATLRPHTEVLGILDDGRRVTGIRTADG--
MAV_0142|M.avium_104                GGSLRIRRALTALARRVVIRCGEVVSVADDG----------RTVLADG-T
                                     .      .  :                                   *  

MAB_1499|M.abscessus_ATCC_1997      TYRGEAVVMCAGAAHGGLARELLGDFPVRRVRLQMMQTAALGEELTTAIA
Mvan_0054|M.vanbaalenii_PYR-1       TYDADVVIVCAGAAHGGLVRDLAGDLPVRRVRLQMMQTAPLGEQLTTAIA
MSMEG_0288|M.smegmatis_MC2_155      RHESDIVLVCAGAAHGGLVRDLAGELPVRRVRLQMMQTEPLGERLTTAIA
TH_0796|M.thermoresistible__bu      RHDGDVVIVCAGAAHGGLX-------------------------------
MMAR_4421|M.marinum_M               TYTAEQLVVCPGAWAPELLSQLGIPITVQRQVMYWLDP----------VG
Mflv_3080|M.gilvum_PYR-GCK          TLDADIVVCAAGFWGAQLARQVGLVLPLVPMAHQYARTG-----QIAELV
MAV_0142|M.avium_104                VLRADRVLICAGVATPKLFGPLG---------------------------
                                       .: :: ..*     *                                

MAB_1499|M.abscessus_ATCC_1997      DGDSLRYYPAFAGPALDALNATQLQEPTAAEHKMQLLCVQRLHGGLTIGD
Mvan_0054|M.vanbaalenii_PYR-1       DGDSLRYYPGFAGGALDTLRRSESQDPVADEHHMQLLCVQRLHGGLTIGD
MSMEG_0288|M.smegmatis_MC2_155      DADSFRYYPGFAGPALNTLRDNQPQHRVADGQHMQLLCVQRLHGGLTIGD
TH_0796|M.thermoresistible__bu      -GCGCR--------------------------------------------
MMAR_4421|M.marinum_M               GTAGFRDHPIFIAENDSGAQIYGFPAIDGPRGGVKVAFFR--------KG
Mflv_3080|M.gilvum_PYR-GCK          GRNTEIAEAGLPILRHQDQDLYFREHGDRLGIGSYMHRPMPVDMTTLLTD
MAV_0142|M.avium_104                --VGFVPHTRFTYRGADATGAACLSAPEGYGLPLGG------------TG
                                                                                      

MAB_1499|M.abscessus_ATCC_1997      THEYAEPFAFDVDEAPYRHLITTAEELLGRKLPP-VVRRWAGVYSQCTDP
Mvan_0054|M.vanbaalenii_PYR-1       THEYTEPFDFDVTEAPYSYLTGVVEELLGRSLPP-IRRRWAGVYSQCVDP
MSMEG_0288|M.smegmatis_MC2_155      THEYTEPFGFDVHEEPYTYLLDVVEEFLGRKLPP-IRQRWAGVYSQCLDP
TH_0796|M.thermoresistible__bu      --------------------------------------------------
MMAR_4421|M.marinum_M               IACTPDTIDRVVGPQEIHEMITRVGELLPALAGT-CLQAATCMYSNTPDQ
Mflv_3080|M.gilvum_PYR-GCK          TAGEAMPSMLPFTEEDFAPAWHAATDLIPALRDSKVEEAFNGIFSFTTDG
MAV_0142|M.avium_104                RWAFGQEVADPATVRALFPSLVAVDRVDCVSVRAPWLDSGGDGWTVARRG
                                                                                      

MAB_1499|M.abscessus_ATCC_1997      DQIVYRRQAAPAVWVVTGPGGRG------------MTLGPAIGADTADLM
Mvan_0054|M.vanbaalenii_PYR-1       ERLAYREQVSPGVWVVTGPGGRG------------MTLGPVIGEQTTNEI
MSMEG_0288|M.smegmatis_MC2_155      EQLVCRTAPEDDIWVITGPGGRG------------MTLGPAIAEQTADMI
TH_0796|M.thermoresistible__bu      --------------------------------------------------
MMAR_4421|M.marinum_M               HFVIARHPYCPAVTVACGFSGHG------------FKFVPVVGEILADLV
Mflv_3080|M.gilvum_PYR-GCK          FSIMGEHRDLAGFWVAEAVWVTHSAGVARATAEWIIEGTPTIDTHECDLY
MAV_0142|M.avium_104                RVLAFVGANLMKFGPLLGELLAR---------------AALSDDIPAELL
                                                                                      

MAB_1499|M.abscessus_ATCC_1997      NL------------------------------------------------
Mvan_0054|M.vanbaalenii_PYR-1       GL------------------------------------------------
MSMEG_0288|M.smegmatis_MC2_155      GL------------------------------------------------
TH_0796|M.thermoresistible__bu      --------------------------------------------------
MMAR_4421|M.marinum_M               TEGATSQPISLFDPQRLVTV------------------------------
Mflv_3080|M.gilvum_PYR-GCK          RFEDVARSPRFIAQTSAQAFVEVYDVIHPHQYRTALRGLRTSPFYPRQCE
MAV_0142|M.avium_104                LD------------------------------------------------
                                                                                      

MAB_1499|M.abscessus_ATCC_1997      --------------------------------------------------
Mvan_0054|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0288|M.smegmatis_MC2_155      --------------------------------------------------
TH_0796|M.thermoresistible__bu      --------------------------------------------------
MMAR_4421|M.marinum_M               --------------------------------------------------
Mflv_3080|M.gilvum_PYR-GCK          LGASFYEGGGWERPAWYGANDRLVQRLFDDGLAVPHRDEWAARNWSPISI
MAV_0142|M.avium_104                --------------------------------------------------
                                                                                      

MAB_1499|M.abscessus_ATCC_1997      --------------------------------------------------
Mvan_0054|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0288|M.smegmatis_MC2_155      --------------------------------------------------
TH_0796|M.thermoresistible__bu      --------------------------------------------------
MMAR_4421|M.marinum_M               --------------------------------------------------
Mflv_3080|M.gilvum_PYR-GCK          AEAHWTRECVAMYDMTPLTRYEVSGSGAAAFLQQMTTNNVDKSVGSVTYT
MAV_0142|M.avium_104                --------------------------------------------------
                                                                                      

MAB_1499|M.abscessus_ATCC_1997      --------------------------------------------------
Mvan_0054|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0288|M.smegmatis_MC2_155      --------------------------------------------------
TH_0796|M.thermoresistible__bu      --------------------------------------------------
MMAR_4421|M.marinum_M               --------------------------------------------------
Mflv_3080|M.gilvum_PYR-GCK          LLLDESGGIRSDLTVARLGPEHFQVGANSPMDFDWLSRRKPPGVVVRDIT
MAV_0142|M.avium_104                --------------------------------------------------
                                                                                      

MAB_1499|M.abscessus_ATCC_1997      --------------------------------------------------
Mvan_0054|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0288|M.smegmatis_MC2_155      --------------------------------------------------
TH_0796|M.thermoresistible__bu      --------------------------------------------------
MMAR_4421|M.marinum_M               --------------------------------------------------
Mflv_3080|M.gilvum_PYR-GCK          GGTCCLGVWGPRAREVIAPLCPDNLSHKAFAYFRAMHTHLGAIPVVMMRV
MAV_0142|M.avium_104                --------------------------------------------------
                                                                                      

MAB_1499|M.abscessus_ATCC_1997      --------------------------------------------------
Mvan_0054|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0288|M.smegmatis_MC2_155      --------------------------------------------------
TH_0796|M.thermoresistible__bu      --------------------------------------------------
MMAR_4421|M.marinum_M               --------------------------------------------------
Mflv_3080|M.gilvum_PYR-GCK          SYVGELGWEIYAGAEYGAALWDLIDEAGAAHGIIPAGRIAFNSLRIEKGY
MAV_0142|M.avium_104                --------------------------------------------------
                                                                                      

MAB_1499|M.abscessus_ATCC_1997      --------------------------------------------------
Mvan_0054|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0288|M.smegmatis_MC2_155      --------------------------------------------------
TH_0796|M.thermoresistible__bu      --------------------------------------------------
MMAR_4421|M.marinum_M               --------------------------------------------------
Mflv_3080|M.gilvum_PYR-GCK          RSWGTDMTAEHRPAAAGLDFAVRVDKGDFVGRQALLTAGSPDATLRSIVF
MAV_0142|M.avium_104                --------------------------------------------------
                                                                                      

MAB_1499|M.abscessus_ATCC_1997      --------------------------------------------------
Mvan_0054|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0288|M.smegmatis_MC2_155      --------------------------------------------------
TH_0796|M.thermoresistible__bu      --------------------------------------------------
MMAR_4421|M.marinum_M               --------------------------------------------------
Mflv_3080|M.gilvum_PYR-GCK          DDPDAAVLGKEPVSVGDTCVGYVTSAGYSATIGRTIAYAWLPAGLVIGET
MAV_0142|M.avium_104                --------------------------------------------------
                                                                                      

MAB_1499|M.abscessus_ATCC_1997      -----------------------------
Mvan_0054|M.vanbaalenii_PYR-1       -----------------------------
MSMEG_0288|M.smegmatis_MC2_155      -----------------------------
TH_0796|M.thermoresistible__bu      -----------------------------
MMAR_4421|M.marinum_M               -----------------------------
Mflv_3080|M.gilvum_PYR-GCK          VSVAYRGVTYSATVHAEPVVDPDMSRIKR
MAV_0142|M.avium_104                -----------------------------