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QVTIIGAGILGTAHAWHAVRRGHHVIHLEREVEARGATVRNFGLVWVSGRASGELEASLRSRALWEEIGA EVPAIGFRPCGSLTLLRTPAEVAVAEEVCGRADAASRGFRLLEPVEAREINPVLRGKFLAALHCDRDGAV ESRQALPAIRAVLDATGRYTFVPGTEARAVDGTRVHDDRGNTYDADVVIVCAGAAHGGLVRDLAGDLPVR RVRLQMMQTAPLGEQLTTAIADGDSLRYYPGFAGGALDTLRRSESQDPVADEHHMQLLCVQRLHGGLTIG DTHEYTEPFDFDVTEAPYSYLTGVVEELLGRSLPPIRRRWAGVYSQCVDPERLAYREQVSPGVWVVTGPG GRGMTLGPVIGEQTTNEIGL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0054 | - | - | 100% (371) | FAD dependent oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_2290 | - | 2e-09 | 29.05% (210) | FAD dependent oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_3080 | - | 2e-11 | 29.05% (241) | FAD dependent oxidoreductase |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1499 | - | 1e-145 | 68.00% (375) | putative FAD dependent oxidoreductase |
| M. marinum M | MMAR_4420 | gcvT_2 | 4e-05 | 27.80% (259) | aminomethyltransferase GcvT_2 |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_0288 | - | 1e-157 | 72.63% (369) | FAD dependent oxidoreductase, putative |
| M. thermoresistible (build 8) | TH_0796 | - | 1e-76 | 70.71% (198) | FAD dependent oxidoreductase, putative |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_0054|M.vanbaalenii_PYR-1 ----MQVTIIGAGILGTAHAWHAVRRGHHVIHLEREV---EARGATVRNF
MAB_1499|M.abscessus_ATCC_1997 ----MRVIVVGGGILGTAHAWAAVERGHEVVHLEREV---EARGATVRNF
MSMEG_0288|M.smegmatis_MC2_155 ------MTIIGGGILGTAHAVEAVRRGHRVVHLEREA---EARGATVRNF
TH_0796|M.thermoresistible__bu ------VIIIGGGILGTAHAVEAVRRGHQVVQLEREG---EARGATVRNF
Mflv_3080|M.gilvum_PYR-GCK MPRTPRVVVIGAGIVGTSLADELTARGWTDVTVVDRGPLFATGGSTSHAP
MMAR_4420|M.marinum_M --MGPKIVIVGAGIVGASLADELTARGVIDVTVVDRGPLFTTGGSTSHAP
: ::*.**:*:: * . ** : : . : *:* :
Mvan_0054|M.vanbaalenii_PYR-1 GLVWVSGRASGELEASLRSRALWEEIGAEVPAIGFRPCGSLTLLRTPAEV
MAB_1499|M.abscessus_ATCC_1997 GLVWVSGRSALELKIAQRSRDLWQGIAKLVPGIGFRQMGSFTLLRTHEEV
MSMEG_0288|M.smegmatis_MC2_155 GLVWISGRSTAELDATLRSRELWEKLAVDVPGIGFRPAGSITLVRTPAEL
TH_0796|M.thermoresistible__bu GLVWVSGRAPAELDTALRARELWERLGAAIPGIGFRPAGSLTLLKTLDEV
Mflv_3080|M.gilvum_PYR-GCK GLVFQTNPSKTMTVFARYTVEKFAALQHPG-GWAFNPVGGLEVATTPERM
MMAR_4420|M.marinum_M GLVFATNPSKTMSAFARYTVDKFSGLHHRD-GAVFNRVGGLEVATTAERW
***: :. : : : : : . *. *.: : * .
Mvan_0054|M.vanbaalenii_PYR-1 AVAEEVCGRADAASRGFRLLEPVEAREINPVLRG-KFLAALHCDRDGAVE
MAB_1499|M.abscessus_ATCC_1997 AVAEEVMARSDADERGFALLEPGAVQRQNPALRG-KFLAGLHCARDAAVE
MSMEG_0288|M.smegmatis_MC2_155 AVAQEAATRSDAGHRGFTLLEPDEVRELNPALRG-RFLGGLHCALDAAVE
TH_0796|M.thermoresistible__bu AVAEQAAARADAGRRGFTVVDAEQARRLNPALRG-DFLAALHCSRDAAVE
Mflv_3080|M.gilvum_PYR-GCK ADLHRKAGWAQSWGIDGRLLTPSECVQLHPLVDRDRILGGFHTPADGLAK
MMAR_4420|M.marinum_M ADLHRKAGWAQAWGVPGRLVGPDQCVELHPLLDRAGILGGFHTPSDGLAS
* .. ::: :: . . :* : :*..:* *. ..
Mvan_0054|M.vanbaalenii_PYR-1 SRQALPAIRAVLDATGRYTFVPGTEARAVD----GTRVHDDRGNTYDADV
MAB_1499|M.abscessus_ATCC_1997 SRVALPAMRLHLKTNGCYSFVAGREVRAIDTSSAGVSVRTDDGETYRGEA
MSMEG_0288|M.smegmatis_MC2_155 SRQALPAIREHLTASGRYEFVAGVEARGVEN----RTVRDDRGNRHESDI
TH_0796|M.thermoresistible__bu SRRAMPAIRAHLAGTGRYTFRPGTEARSVS----GPSVRDDRGGRHDGDV
Mflv_3080|M.gilvum_PYR-GCK ALRAAEAQARRAEARGATLRPHTEVLGILDDGRRVTGIRTADG-TLDADI
MMAR_4420|M.marinum_M AVRAVEAQARRAIARGAVFLAETEVQRVADHNGLVTGVHTSRG-VIEADI
: * * * . :: * .:
Mvan_0054|M.vanbaalenii_PYR-1 VIVCAGAAHGGLVRDLAGDLPVRRVRLQMMQTAPLGEQLTTAIADGDSLR
MAB_1499|M.abscessus_ATCC_1997 VVMCAGAAHGGLARELLGDFPVRRVRLQMMQTAALGEELTTAIADGDSLR
MSMEG_0288|M.smegmatis_MC2_155 VLVCAGAAHGGLVRDLAGELPVRRVRLQMMQTEPLGERLTTAIADADSFR
TH_0796|M.thermoresistible__bu VIVCAGAAHGGLX--------------------------------GCGCR
Mflv_3080|M.gilvum_PYR-GCK VVCAAGFWGAQLARQVGLVLPLVPMAHQYARTGQIAELVGRNTEIAEAGL
MMAR_4420|M.marinum_M VVCAAGFWGAQLAKQVGLVLPLVPMAHQYAKTGQVAPLVGRNTEDAPASL
*: .** . * . .
Mvan_0054|M.vanbaalenii_PYR-1 YYPGFAGGALDTLRRSESQDPVADEHHMQLLCVQRLHGGLTIGDTHEYTE
MAB_1499|M.abscessus_ATCC_1997 YYPAFAGPALDALNATQLQEPTAAEHKMQLLCVQRLHGGLTIGDTHEYAE
MSMEG_0288|M.smegmatis_MC2_155 YYPGFAGPALNTLRDNQPQHRVADGQHMQLLCVQRLHGGLTIGDTHEYTE
TH_0796|M.thermoresistible__bu --------------------------------------------------
Mflv_3080|M.gilvum_PYR-GCK PILRHQDQDLYFREHGDRLGIGSYMHRPMPVDMTTLLT-DTAGEAMPSML
MMAR_4420|M.marinum_M PILRHQDGDLYFREHVDRLGIGSYGHQPMPVDMSTLLA-DTAGEPMPSML
Mvan_0054|M.vanbaalenii_PYR-1 PFDFDVTEAPYSYLTGVVEELLGRSLPPIRRRWAGVYSQCVD------PE
MAB_1499|M.abscessus_ATCC_1997 PFAFDVDEAPYRHLITTAEELLGRKLPPVVRRWAGVYSQCTD------PD
MSMEG_0288|M.smegmatis_MC2_155 PFGFDVHEEPYTYLLDVVEEFLGRKLPPIRQRWAGVYSQCLD------PE
TH_0796|M.thermoresistible__bu --------------------------------------------------
Mflv_3080|M.gilvum_PYR-GCK PFTEEDFAPAWHAATDLIPALRD---SKVEEAFNGIFSFTTDGFSIMGEH
MMAR_4420|M.marinum_M PFTEEDFEPAWRECVRLLPALGD---TKVDEGFNGIFSFTPDGYSLLGEH
Mvan_0054|M.vanbaalenii_PYR-1 RLAYREQVSPGVWVVTGPGGRGMTLG------PVIGEQTTNEIGL-----
MAB_1499|M.abscessus_ATCC_1997 QIVYRRQAAPAVWVVTGPGGRGMTLG------PAIGADTADLMNL-----
MSMEG_0288|M.smegmatis_MC2_155 QLVCRTAPEDDIWVITGPGGRGMTLG------PAIAEQTADMIGL-----
TH_0796|M.thermoresistible__bu --------------------------------------------------
Mflv_3080|M.gilvum_PYR-GCK RDLAGFWVAEAVWVTHSAGVARATAEWIIEGTPTIDTHECDLYRFEDVAR
MMAR_4420|M.marinum_M RELGGFWVAEAVWVTHSAGVAKAVAEWIVDGTPSIDVHECDLYRFEDFAR
Mvan_0054|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_1499|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0288|M.smegmatis_MC2_155 --------------------------------------------------
TH_0796|M.thermoresistible__bu --------------------------------------------------
Mflv_3080|M.gilvum_PYR-GCK SPRFIAQTSAQAFVEVYDVIHPHQYRTALRGLRTSPFYPRQCELGASFYE
MMAR_4420|M.marinum_M SPRFIDETCAQAFVEVYDIVHPHQYRSALRGLRTSPFHHRQRELGAYFYE
Mvan_0054|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_1499|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0288|M.smegmatis_MC2_155 --------------------------------------------------
TH_0796|M.thermoresistible__bu --------------------------------------------------
Mflv_3080|M.gilvum_PYR-GCK GGGWERPAWYGANDRLVQRLFDDGLAVPHRDEWAARNWSPISIAEAHWTR
MMAR_4420|M.marinum_M GGGWERPAWFQANAELVRELAGRNVAFPERDDWAARYWSPIAIAEAQWTR
Mvan_0054|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_1499|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0288|M.smegmatis_MC2_155 --------------------------------------------------
TH_0796|M.thermoresistible__bu --------------------------------------------------
Mflv_3080|M.gilvum_PYR-GCK ECVAMYDMTPLTRYEVSGSGAAAFLQQMTTNNVDKSVGSVTYTLLLDESG
MMAR_4420|M.marinum_M ERVALYDMTPLTRYEVSGAGAVDLLQRLTTNDIDKGVGSVTYTLMLDETG
Mvan_0054|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_1499|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0288|M.smegmatis_MC2_155 --------------------------------------------------
TH_0796|M.thermoresistible__bu --------------------------------------------------
Mflv_3080|M.gilvum_PYR-GCK GIRSDLTVARLGPEHFQVGANSPMDFDWLSRRKPP--GVVVRDITGGTCC
MMAR_4420|M.marinum_M GIRSDLTVARLGTARFQVGANGPQDFDWLSRHLPQDGSVTLRDITGATCC
Mvan_0054|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_1499|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0288|M.smegmatis_MC2_155 --------------------------------------------------
TH_0796|M.thermoresistible__bu --------------------------------------------------
Mflv_3080|M.gilvum_PYR-GCK LGVWGPRAREVIAPLCPDNLSHKAFAYFRAMHTHLGAIPVVMMRVSYVGE
MMAR_4420|M.marinum_M IGVWGPAARDLVQPLCRDDLSHQAFPYFRLLQTYLEAIPVTMLRVSYVGE
Mvan_0054|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_1499|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0288|M.smegmatis_MC2_155 --------------------------------------------------
TH_0796|M.thermoresistible__bu --------------------------------------------------
Mflv_3080|M.gilvum_PYR-GCK LGWEIYAGAEYGAALWDLIDEAGAAHGIIPAGRIAFNSLRIEKGYRSWGT
MMAR_4420|M.marinum_M LGWEIYTEASYGGALWDLLWAAGAGHQAIAAGRIAFNSLRMEKGYRAWGT
Mvan_0054|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_1499|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0288|M.smegmatis_MC2_155 --------------------------------------------------
TH_0796|M.thermoresistible__bu --------------------------------------------------
Mflv_3080|M.gilvum_PYR-GCK DMTAEHRPAAAGLDFAVRVDKGDFVGRQALLTAGSPDATLRSIVFDDPDA
MMAR_4420|M.marinum_M DMTAEHRPDEAGLGFAVRMSK-DFIGKAALVDAAAR-KVLQCLVFDDPAA
Mvan_0054|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_1499|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0288|M.smegmatis_MC2_155 --------------------------------------------------
TH_0796|M.thermoresistible__bu --------------------------------------------------
Mflv_3080|M.gilvum_PYR-GCK AVLGKEPVSVGDTCVGYVTSAGYSATIGRTIAYAWLPAGLVIGETVSVAY
MMAR_4420|M.marinum_M AALGKEPVLAGDVCIGFVTSAGYSPTIGRTIAYAWLPAESSIGDTVTVDH
Mvan_0054|M.vanbaalenii_PYR-1 ------------------------
MAB_1499|M.abscessus_ATCC_1997 ------------------------
MSMEG_0288|M.smegmatis_MC2_155 ------------------------
TH_0796|M.thermoresistible__bu ------------------------
Mflv_3080|M.gilvum_PYR-GCK RGVTYSATVHAEPVVDPDMSRIKR
MMAR_4420|M.marinum_M RGRRYPASVHQQPVVDPESTRIRR