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VNKSMQRLARSAVACCVAGALVSGCSSAPGDTSQETDGAKPSGQEITVATDATYRPFETVDPATKKIVGL DADLVEAIGDTLGLTVKLTNVGFDSIVPGLQARKYDAAASGISVTPEREKVVDFVPYMSAGSGLAVQKGN PHDLKMEPLALCGHTIGAPKGTIQAIGQLPEISAKCVAEGKPEISISQFPSQDAVNLALSSGRIDAAMAA NISLAIQVEESDGALELAPGDPYDPSPVGIAFPKGSDLLPAVKTAMAQLDSSGELKKIVTKWGMPENSIY TGAS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0176 | - | - | 100% (284) | glutamine ABC transporter periplasmic-binding protein |
| M. smegmatis MC2 155 | MSMEG_3235 | - | 5e-37 | 34.26% (289) | ABC-type amino acid transport system, secreted component |
| M. smegmatis MC2 155 | MSMEG_1612 | - | 9e-32 | 31.12% (286) | extracellular solute-binding protein, family protein 3 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0419c | glnH | 2e-06 | 24.80% (254) | glutamine-binding lipoprotein |
| M. gilvum PYR-GCK | Mflv_3583 | - | 6e-36 | 34.13% (293) | extracellular solute-binding protein |
| M. tuberculosis H37Rv | Rv0411c | glnH | 2e-06 | 24.80% (254) | glutamine-binding lipoprotein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0277c | - | 1e-19 | 26.14% (264) | amino acid ABC transporter permease |
| M. marinum M | MMAR_0061 | glnQ | 4e-07 | 22.22% (243) | ABC transporter permease protein GlnQ |
| M. avium 104 | MAV_0059 | - | 9e-08 | 24.26% (235) | amino acid ABC transporter, permease protein, |
| M. thermoresistible (build 8) | TH_0053 | - | 3e-30 | 34.96% (226) | ABC-type amino acid transport system, secreted component |
| M. ulcerans Agy99 | MUL_2809 | glnH | 3e-06 | 24.02% (254) | glutamine-binding lipoprotein GlnH |
| M. vanbaalenii PYR-1 | Mvan_2832 | - | 8e-33 | 32.76% (293) | extracellular solute-binding protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3583|M.gilvum_PYR-GCK ------------------MLGGIQGRQTRLWRVVAVFAATGAMALSGCSS
Mvan_2832|M.vanbaalenii_PYR-1 ------------------MVAGIQDRRTRIWRVAAVFAAVGALALSGCSS
TH_0053|M.thermoresistible__bu --------------------------------------------------
MSMEG_0176|M.smegmatis_MC2_155 -----------------------MNKSMQRLARSAVACCVAGALVSGCSS
MMAR_0061|M.marinum_M --------------MLAVSATILIVLG--LALAAPALADHNQCAPAGVDS
MAV_0059|M.avium_104 ----MGRRGTRRGKLLALTATVLMVCGSSALLAPPAAADRNQCAPAGPKS
Mb0419c|M.bovis_AF2122/97 MTRRALLARAAAPLAPLALAMVLASCGHSETLGVEATPTLPLPTPVGMEI
Rv0411c|M.tuberculosis_H37Rv MTRRALLARAAAPLAPLALAMVLASCGHSETLGVEATPTLPLPTPVGMEI
MUL_2809|M.ulcerans_Agy99 MRRLPGLRRAASALAVLALVITLDGCGHSEPLKVESTPTLPLPTPVGMEV
MAB_0277c|M.abscessus_ATCC_199 ------------------------------MFRAIVLALLALVAVAGCAA
Mflv_3583|M.gilvum_PYR-GCK SSESPSDEGSPTAVAPAEKVDAIANTVPESIKSTGTLVVGVN-------V
Mvan_2832|M.vanbaalenii_PYR-1 SSEEPVEEGSPTAAAPAEKVDAIANTVPEAIKSTGKLIVGVN-------I
TH_0053|M.thermoresistible__bu -------------------------------------------------V
MSMEG_0176|M.smegmatis_MC2_155 APGDTSQETDG------------------AKPSGQEITVATD-------A
MMAR_0061|M.marinum_M AMVLPADLSSATTAGSDEDVQTTAGVVPLSSVNIGDLGLGTPGVLTAGTL
MAV_0059|M.avium_104 AAVLPENLTRGGSMS-QPDEHTTPTVEPLSSVRIDTLGLGTPGVLTVGTL
Mb0419c|M.bovis_AF2122/97 MPPQPPLPPDSSSQDCDPTASLRPFATKAEADAAVADIRARGRLIVGLDI
Rv0411c|M.tuberculosis_H37Rv MPPQPPLPPDSSSQDCDPTASLRPFATKAEADAAVADIRARGRLIVGLDI
MUL_2809|M.ulcerans_Agy99 MPPEPPLPADSSSQDCDPTASLRPFPTKAEADAAVADIRARGRLIVGLDI
MAB_0277c|M.abscessus_ATCC_199 PTQEPLRVGTEG--------------------------------------
Mflv_3583|M.gilvum_PYR-GCK PYAPNEFKD-PEGKLVGFDVDLMNAIAGTLG---LTPEYKEADFAKIIPS
Mvan_2832|M.vanbaalenii_PYR-1 PYAPNEFKD-ESGKIVGFDVDLMNAIAGTLG---LTPEYREADFAKIIPS
TH_0053|M.thermoresistible__bu PYKPNEFKN-AAGEIVGFDVDLMNAVARTLG---LAPEYRELPFEAILPS
MSMEG_0176|M.smegmatis_MC2_155 TYRPFETVDPATKKIVGLDADLVEAIGDTLG---LTVKLTNVGFDSIVPG
MMAR_0061|M.marinum_M SDAPPNTCINSTGQFTGFDNELLRAIAAKLG---LQVRFVGTDFSGLLAQ
MAV_0059|M.avium_104 SGAPPNVCITPTGQYSGFDNQLLRAIAGKLG---LQVRFVGTDFAGLLAQ
Mb0419c|M.bovis_AF2122/97 GSNLFSFRDPITGEITGFDVDIAGEVARDIFGVPSHVEYRILSAAERVTA
Rv0411c|M.tuberculosis_H37Rv GSNLFSFRDPITGEITGFDVDIAGEVARDIFGVPSHVEYRILSAAERVTA
MUL_2809|M.ulcerans_Agy99 GSNLFSFRDPITGEITGFDVDIASEVARDIFGGPTHVEYRILSAAERITA
MAB_0277c|M.abscessus_ATCC_199 VYAPFSFHDGHTGELTGYDVDVARAVGEKLG---RPVEFVEIPWDAIFAG
. : * * :: :. : . ..
Mflv_3583|M.gilvum_PYR-GCK IQGGTFDVGMSSFTDSKEREEQVDFVTYFSAG-TAWAQPAGG----DINP
Mvan_2832|M.vanbaalenii_PYR-1 IQGGTFNVGMSSFTDSKEREQQVDFVTYFSAG-TLWAQPAGG----QIDP
TH_0053|M.thermoresistible__bu VRAGDVHVGMASLTVTPERSAGADFVTYFQAG-TLWAQPAGG----AVNP
MSMEG_0176|M.smegmatis_MC2_155 LQARKYDAAASGISVTPEREKVVDFVPYMSAG-SGLAVQKGNPHDLKMEP
MMAR_0061|M.marinum_M VAARRFDVGSASVKLTEARRRTVAFTNGYDFGYYSLVVPPGS--AITKFS
MAV_0059|M.avium_104 VASRRFDVGSSSIKATDERRQTVAFTNGYDFGYYALVVPPGS--AIKEFT
Mb0419c|M.bovis_AF2122/97 LQKSQVDIVVKTMSITCERRKLVNFSTVYLDANQRILAPRDS---PITKV
Rv0411c|M.tuberculosis_H37Rv LQKSQVDIVVKTMSITCERRKLVNFSTVYLDANQRILAPRDS---PITKV
MUL_2809|M.ulcerans_Agy99 LQSSQVDVVVKTMTITCERRKLVNFSTVYLDANQRILTSRDS---PIFKV
MAB_0277c|M.abscessus_ATCC_199 LDAERFDVVANQVTITPARKAKYDISTPYAVGEGVIVTRADD---NSIHS
: . .. : * : . ..
Mflv_3583|M.gilvum_PYR-GCK EDACGKKVAVQATTVQETDELP----------------------------
Mvan_2832|M.vanbaalenii_PYR-1 ENACGKKVAVQATTVQETDELP----------------------------
TH_0053|M.thermoresistible__bu ADACGLRVGVAYATIQESDEVP----------------------------
MSMEG_0176|M.smegmatis_MC2_155 LALCGHTIGAPKGTIQAIGQLP----------------------------
MMAR_0061|M.marinum_M DLAPGQRIGVVQGTVEESYVVNSLHLQPVKYPDFATVYGNLKTHQIDAWV
MAV_0059|M.avium_104 DLAAGQRIGVVQGTVEESYVVDTLHLQPVKYPDFATVYASLKTRQIDAWV
Mb0419c|M.bovis_AF2122/97 SDLSGKRVCVARGTT-----------------------------------
Rv0411c|M.tuberculosis_H37Rv SDLSGKRVCVARGTT-----------------------------------
MUL_2809|M.ulcerans_Agy99 SDLSGKRVCVARGTT-----------------------------------
MAB_0277c|M.abscessus_ATCC_199 LSDVRGKVAAENATSNWSQIARDAGARVEAVEG-----------------
: . *
Mflv_3583|M.gilvum_PYR-GCK ---ARSKKCVDEGKPAIEIIPFDS-----------QDAATNAVVLGQADA
Mvan_2832|M.vanbaalenii_PYR-1 ---ARSKKCTDAGQPAIEIIAFDS-----------QDAATNAVVLGQADA
TH_0053|M.thermoresistible__bu ---FKSEICTAAGKPPIDKVVYVS-----------QDDLTEALMNGEIDA
MSMEG_0176|M.smegmatis_MC2_155 ---EISAKCVAEGKPEISISQFPS-----------QDAVNLALSSGRIDA
MMAR_0061|M.marinum_M APGNQAEAAIRPGDPAVLVANTFGAGDFVAYVVARDNRPLLDALNSGLDA
MAV_0059|M.avium_104 APAGQAATTIQPGDPAVVVANTISPGNFVAYAVAKDNKPLVDALNSGLDA
Mb0419c|M.bovis_AF2122/97 -----SLRRIREIAPPPVIVSVVN-----------WADCLVALQQREIDA
Rv0411c|M.tuberculosis_H37Rv -----SLRRIREIAPPPVIVSVVN-----------WADCLVALQQREIDA
MUL_2809|M.ulcerans_Agy99 -----SLRRIREIAPPPVIVSVVN-----------WADCLVALQQREIDA
MAB_0277c|M.abscessus_ATCC_199 --FTQSITLLSQGRVDVVINDSIAVYAYLASTG--DPAVKIAGATGQRSE
: .
Mflv_3583|M.gilvum_PYR-GCK MSADSPVTLYAIKQTNGKLEQA-------------------GETFDSAPY
Mvan_2832|M.vanbaalenii_PYR-1 MSADSPVTLYAIKQTNGKLVQA-------------------GEVFDSAPY
TH_0053|M.thermoresistible__bu MSADSPVTGFAVKTSGGALQEA-------------------GEIFSPAPY
MSMEG_0176|M.smegmatis_MC2_155 AMAANISLAIQVEESDGALELAP------------------GDPYDPSPV
MMAR_0061|M.marinum_M VIADGTWSQLYSKWVPRTLPPGWKPGSRAVAAPTLPDFAAIAAAHRHKPV
MAV_0059|M.avium_104 VIADGTWSNLYSQWVPRTLPPGWKPGSQAVAPPKLPDFAAIAASQHHKAV
Mb0419c|M.bovis_AF2122/97 VSTDDTILAGLVEEDPYLHIVG--------------------PDMADQPY
Rv0411c|M.tuberculosis_H37Rv VSTDDTILAGLVEEDPYLHIVG--------------------PDMADQPY
MUL_2809|M.ulcerans_Agy99 VSTDDTILAGLVEEDPYLHIVG--------------------PNMANQPY
MAB_0277c|M.abscessus_ATCC_199 QGFAARKNSGLLPDLDKALDQLAADG---------TLTRISQKYLKTDAS
.
Mflv_3583|M.gilvum_PYR-GCK GWPVEKGSPLAQ--------SLLQALQHLIDNGKYQEIAANWGLEEGMID
Mvan_2832|M.vanbaalenii_PYR-1 GWPVEKGSPLAQ--------SLLQALEHLIETGKYKEIAANWGLEEGMID
TH_0053|M.thermoresistible__bu GWPVTRGSPLAE--------SLRQALEHLIATGEYRTIATMWGVEKGMID
MSMEG_0176|M.smegmatis_MC2_155 GIAFPKGSDLLP--------AVKTAMAQLDSSGELKKIVTKWGMPENSIY
MMAR_0061|M.marinum_M GPAAPKSALTQLRDSFFDWDMYRQAIPTLFKTGLPNTLILTLSASIIGLA
MAV_0059|M.avium_104 GPAAPKSTLAQLRDSFFDWDMYRQAIPTLLRTGLPNTLILTFSASVIGLV
Mb0419c|M.bovis_AF2122/97 GVGINLDNTGLVR-------FVNGTLERIRNDGTWNTLYRKWLTVLGPAP
Rv0411c|M.tuberculosis_H37Rv GVGINLDNTGLVR-------FVNGTLERIRNDGTWNTLYRKWLTVLGPAP
MUL_2809|M.ulcerans_Agy99 GIGINLDNTGLVR-------FVNGTLERIRNDGTWNTLYRKWLSVLGPAP
MAB_0277c|M.abscessus_ATCC_199 GTTKPQAGKGDSGSTRSDTQLVLDNLWPMARAMITVTLPLTAISFVIGLV
* : : :
Mflv_3583|M.gilvum_PYR-GCK KPVINGAIS-----------------------------------------
Mvan_2832|M.vanbaalenii_PYR-1 KPVINGAVS-----------------------------------------
TH_0053|M.thermoresistible__bu RPEINAAAG-----------------------------------------
MSMEG_0176|M.smegmatis_MC2_155 TGAS----------------------------------------------
MMAR_0061|M.marinum_M LGMALAIAGISHQRWLRWPARVYTDIFRGLPEVVIILIIGLGVGPIVGGL
MAV_0059|M.avium_104 LGMVLAVAGISHARWLRWPARVYTDVFRGLPEVVIILLIGLGIGPIVGGL
Mb0419c|M.bovis_AF2122/97 APPTPRYVD-----------------------------------------
Rv0411c|M.tuberculosis_H37Rv APPTPRYVD-----------------------------------------
MUL_2809|M.ulcerans_Agy99 APPRPRYVD-----------------------------------------
MAB_0277c|M.abscessus_ATCC_199 IALGVALARMSGHRVVTGLARIYISVIRGTPLLLQLFLIFFALPEFG---
Mflv_3583|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2832|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0053|M.thermoresistible__bu --------------------------------------------------
MSMEG_0176|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0061|M.marinum_M TNNNPYPLGIAALGLMAGAYVGEILRSGIQSVDPGQLEASRALGFSYSAA
MAV_0059|M.avium_104 TNNNPYPLGIAALGMMAAAYIGEILRSGIQSVDPGQLEASRALGFSYATA
Mb0419c|M.bovis_AF2122/97 --------------------------------------------------
Rv0411c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_2809|M.ulcerans_Agy99 --------------------------------------------------
MAB_0277c|M.abscessus_ATCC_199 VKISPFPAAVIAFSLNVGGYAAEIIRSSILSIPRGQWEAASSLGMSYSTT
Mflv_3583|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2832|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0053|M.thermoresistible__bu --------------------------------------------------
MSMEG_0176|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0061|M.marinum_M MRLVVVPQGVRRVLPALVNQFIALLKASALVYFLGLIAQQRELFQVGRDL
MAV_0059|M.avium_104 MRLVVVPQGVRRVLPALVNQFIALLKASALVYFLGLVADQRELFQVGRDL
Mb0419c|M.bovis_AF2122/97 --------------------------------------------------
Rv0411c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_2809|M.ulcerans_Agy99 --------------------------------------------------
MAB_0277c|M.abscessus_ATCC_199 LWRIVIPQASRVAVPPLSNTLISLVKDTSLASAILVTDVMRTAQVAAAP-
Mflv_3583|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2832|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0053|M.thermoresistible__bu --------------------------------------------------
MSMEG_0176|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0061|M.marinum_M NAQTGNLSPLVAAGIFYLMLTVPLTHLVNYIDARLRRGRRRLDPEDPPGV
MAV_0059|M.avium_104 NAETGNLSPLVAAGACYLILTVPLTHLVNMIDARLRRGRAAVDPEEPAEM
Mb0419c|M.bovis_AF2122/97 --------------------------------------------------
Rv0411c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_2809|M.ulcerans_Agy99 --------------------------------------------------
MAB_0277c|M.abscessus_ATCC_199 --TFQFFTLYVTAGVYYWIVCMAMSAVQDRLEQRLEKSVAR---------
Mflv_3583|M.gilvum_PYR-GCK ----------
Mvan_2832|M.vanbaalenii_PYR-1 ----------
TH_0053|M.thermoresistible__bu ----------
MSMEG_0176|M.smegmatis_MC2_155 ----------
MMAR_0061|M.marinum_M VSSTIGEEMT
MAV_0059|M.avium_104 LT--FGQEIT
Mb0419c|M.bovis_AF2122/97 ----------
Rv0411c|M.tuberculosis_H37Rv ----------
MUL_2809|M.ulcerans_Agy99 ----------
MAB_0277c|M.abscessus_ATCC_199 ----------