For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
TETPTAISASWLAQAVVDASSEAIVVTDKAGDIVLWNDGAARMFGFTAADALGQSLDLIIPEKQRDRHWK GYHQTMATGVTKYGDSMLAVPATHKDGHRLSIEFSVALLRDDTGEIVGISAIMREVSERRAAERALHARI AELQNELNEVRAGLS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0155 | - | - | 100% (156) | transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_2883 | - | 4e-07 | 28.23% (124) | diguanylate cyclase with PAS/PAC sensor |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | MAV_2508 | - | 5e-10 | 29.13% (127) | PAS domain-containing protein |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_3629 | - | 7e-11 | 30.65% (124) | diguanylate cyclase with PAS/PAC sensor |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2883|M.gilvum_PYR-GCK MRRLSTSAVVLLTFPPVFALSIVAGRATRLGGSEVALVWPAAAVAVMWLL
Mvan_3629|M.vanbaalenii_PYR-1 MKRLSPSAVAFLTFPVVYAVSILAGRATRLGGGEIALVWPAAAVATVWLL
MSMEG_0155|M.smegmatis_MC2_155 --------------------------------------------------
MAV_2508|M.avium_104 --------------------------------------------------
Mflv_2883|M.gilvum_PYR-GCK AVHHCSLRQRAIHVTLLGILAYGMNVATGATVSLSAWFVLVNVVLAVVTV
Mvan_3629|M.vanbaalenii_PYR-1 AARRFSRWQRVAHLSALALATFVVNLFTHATPQLSAWFVLVNLALALVTV
MSMEG_0155|M.smegmatis_MC2_155 --------------------------------------------------
MAV_2508|M.avium_104 --------------------------------------------------
Mflv_2883|M.gilvum_PYR-GCK GLLHYGRSDAVLRDPADLARLVVAVATGTMCAAVLATLYLTPVTGAPAWE
Mvan_3629|M.vanbaalenii_PYR-1 EIIHYRRDEVVLRDPTDLVRVIVAVTAGTVCAAALATMYLVPVTGAPAWE
MSMEG_0155|M.smegmatis_MC2_155 --------------------------------------------------
MAV_2508|M.avium_104 --------------------------------------------------
Mflv_2883|M.gilvum_PYR-GCK TFALFTARNGASALVGVAVWLCLRDVPWKRPRVRPAMLVEGLVVGTIVVF
Mvan_3629|M.vanbaalenii_PYR-1 TFGLFTARNGATALIGVAAWLRLRDVRWTRPRLSPAATVEIIVTGGVVGF
MSMEG_0155|M.smegmatis_MC2_155 --------------------------------------------------
MAV_2508|M.avium_104 --------------------------------------------------
Mflv_2883|M.gilvum_PYR-GCK VFAWSFWLNTGTPMTFVVLLPTTWVALRYSTPVSTLFVIAAANWIVFATL
Mvan_3629|M.vanbaalenii_PYR-1 VLVWIFWLSTGIPLGFLVLLPAMWVALRYSTTVSTVFLLVAAAWIIYSTL
MSMEG_0155|M.smegmatis_MC2_155 --------------------------------------------------
MAV_2508|M.avium_104 ------------------------------------MTSPGADRYLSAAF
Mflv_2883|M.gilvum_PYR-GCK SDRGPLLASDLQVRALLAQGMVFSLTVIVLALALYRDTRVRLIAELEASR
Mvan_3629|M.vanbaalenii_PYR-1 SGRGAFIVPDMQLRALLAQAMVFSLTVLVLALALFRDSRMRLIGQLEAAR
MSMEG_0155|M.smegmatis_MC2_155 --------------------------------------------------
MAV_2508|M.avium_104 RNKS----LPERLRDLEAMVEAITDCAIIQLDANGDVARWCPGAEAMTGY
Mflv_2883|M.gilvum_PYR-GCK DQADQDSELLGAVLDSIHDGVILVDPADRVVLRNARADDSGLVDEVVAAA
Mvan_3629|M.vanbaalenii_PYR-1 DRADQDSELLGAVLDSIHDSVVLADPDGRVVLQNARATDSGLVSDVVSAV
MSMEG_0155|M.smegmatis_MC2_155 --------------------------------------------------
MAV_2508|M.avium_104 SAAEALGRPAALLYTSEDRAAGLAERELAAARESGRCEFEGWRARKNGQR
Mflv_2883|M.gilvum_PYR-GCK RAVG-HGGADGPEPAVPHDVIVSVEDSRTLELTTTPLPRQPQFDVMAFRD
Mvan_3629|M.vanbaalenii_PYR-1 HTPGLVDDMAASASHAPRDIVVSVEDSRILELATTPLSRQSQFTVMAFRD
MSMEG_0155|M.smegmatis_MC2_155 -------------------------------MTETPTAISASWLAQAVVD
MAV_2508|M.avium_104 FRAG-------VALSVFTDDAGSAIGFTTVMRDVTAEHQRAETMFHALLE
*. .. *. :
Mflv_2883|M.gilvum_PYR-GCK VTEVRRNARELREARDLFAGVLQAASEQAIIGTDQDGLITVFNQGAERLL
Mvan_3629|M.vanbaalenii_PYR-1 VTEERRNARELREARDLFAGVLEAASEQAIVGTDPSGCITVFNNGAERLL
MSMEG_0155|M.smegmatis_MC2_155 ASS------------------------EAIVVTDKAGDIVLWNDGAARMF
MAV_2508|M.avium_104 SAP------------------------DAMVIVGPDGRIVLANAQADQMF
: :*:: .. * *.: * * :::
Mflv_2883|M.gilvum_PYR-GCK GWTAEEMIGRPVTDVHDLAEMIVRADELGVPPGFEAFIANVTPDDAEIRE
Mvan_3629|M.vanbaalenii_PYR-1 GWTEEEMLGRTPMDFHYPPEVRARAEELGIPEGFEVFVHNVTPDAAEIRE
MSMEG_0155|M.smegmatis_MC2_155 GFTAADALG-QSLDLIIPEKQRDRHWKG----YHQTMATGVTKYGDSMLA
MAV_2508|M.avium_104 GYPREELIG-REVEILIPPRHRGSHERYR----TGFFAAPAARRMGAGLE
*:. : :* :. . . : .:
Mflv_2883|M.gilvum_PYR-GCK WTYVRRDGSHAEVSLAISQMSDADGCCVGYIGVATDITERKKAEHALAES
Mvan_3629|M.vanbaalenii_PYR-1 WTFVRRDGGHVDVSLAVSLMTDERGTCVGYIGVATDITDQKAAERALAES
MSMEG_0155|M.smegmatis_MC2_155 VPATHKDGHRLSIEFSVALLRDDTGEIVGISAIMREVSERRAAERALHAR
MAV_2508|M.avium_104 LWGMRCDGTVFPVDVSLSPLQTEQGVMV--SAAIRDITEQLAVQAELTET
: ** :..::: : * * . ::::: .: *
Mflv_2883|M.gilvum_PYR-GCK EERFRSAFDTAPMGMFMFTVTPEDAGRITRCNQALADFLGRSTSEVPGMS
Mvan_3629|M.vanbaalenii_PYR-1 EERFRLAFDTAPVGMFMFDVTPDGTGRITRCNTTLADFLGRSTADVLGSS
MSMEG_0155|M.smegmatis_MC2_155 IAELQNELNEVRAGLS----------------------------------
MAV_2508|M.avium_104 RAQAEVLAERDRIAG---DLQDHAIQRVFAVGLALQGTIPRARSADVQQR
. . : .
Mflv_2883|M.gilvum_PYR-GCK VTDLGTNENADGTEGLARLLALTDGEPVSAEVRFRRWDGDTMWGAVSASV
Mvan_3629|M.vanbaalenii_PYR-1 TTELGADESTSSTKGLTGLPTLRKGEPWGAEVAFRRADGATVWGAVSASL
MSMEG_0155|M.smegmatis_MC2_155 --------------------------------------------------
MAV_2508|M.avium_104 LNAAVDDLHAVVQDFRTAIFDLRHTKTDVPGLRQRFDEVIGRLAEGLAAT
Mflv_2883|M.gilvum_PYR-GCK VAAAGADPYGICLVEDITSRKRAEAELQHLALHDPLTGLANRALLVDRVE
Mvan_3629|M.vanbaalenii_PYR-1 VAPPGADPYGICLVEDITSRKRAEADLQFLALHDPLTGLANRTLLMNRME
MSMEG_0155|M.smegmatis_MC2_155 --------------------------------------------------
MAV_2508|M.avium_104 VQYKGPLSVVEGELADQAEAVVAEAIGN-AVRHTAATKLTIAVEVADEVS
Mflv_2883|M.gilvum_PYR-GCK QAIADIGRHAPACVGLLYLDLDGFKPVNDTWGHAAGDEVLNAVARRIENS
Mvan_3629|M.vanbaalenii_PYR-1 QALADEGRHVPGRVGLLFLDLDGFKPVNDTWGHAAGDEVLKAVARRIENS
MSMEG_0155|M.smegmatis_MC2_155 --------------------------------------------------
MAV_2508|M.avium_104 IEVIDNGKGLPDDVS------------------EAGLKTLRRRAERVGGT
Mflv_2883|M.gilvum_PYR-GCK IRPGDTAARLGGDEFAVLCPVIKDSEALHGIAERIRREVRRPLRLRAGRT
Mvan_3629|M.vanbaalenii_PYR-1 IRPGDTAARLGGDEFAVLCPVIGENGELHGVAERIQTELSRPLTLIGGQS
MSMEG_0155|M.smegmatis_MC2_155 --------------------------------------------------
MAV_2508|M.avium_104 LTVGAAAG--GGTRLRWVAPLP----------------------------
Mflv_2883|M.gilvum_PYR-GCK YDRLSASTGAATSGGNSNAESLIAHTDRLMYRAKRNGKDRVADDLVPVEG
Mvan_3629|M.vanbaalenii_PYR-1 YDQLSASVGVAMSGCGRTAEELLHHADRLMYHAKRQGNGGLVGDHTPAGA
MSMEG_0155|M.smegmatis_MC2_155 --------------------------------------------------
MAV_2508|M.avium_104 --------------------------------------------------