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MADTTRTDLSWTGVRVLRRTVSRNLKWLTSGTTLIALHQLCEVSVPVLIGIIVDRAVATGSVEAILRWIA VLAALFVVLTVVYRFGARLLMFAIARESHLLRVESSAKILDPLGIETDYKVGELLSISSDDADEVSYLLD YVPRIVGAVVGTVVCGAVLLSIHLPLGLMVLIGVPVVVFGLQLTAPMIARRVEDQQAEIGRATALATDLI SGQRPLQGIGAQANAAARYRVASRRALTATLRAARIQSIHSGAAAAAGALAAMAVAVVAAYFAIRGSMTV GQLITVIGLAQFLIEPFSLLAVVPSWVAEARASANRVARVLSAPTRHSPVFAADPRDAAARLSVRNATHA GLKNLSFDVEPGEFVAVLTSDVRDAGALIDLLSGYQRAEDKGTVLVGGRRLDQIPLKERREHLLVEHHLS SLFSGTLETNLNVTGTDPRRGRVSVDDALQASCAVDVVDLHPDGLAHAVVERGASLSGGQRQRWTLARAL LADPAVLVLHDPTTAIDTVTEQVIADGIRRLRTRAGRTTVVLTSSPALLAAADRVLLVIDGRLDSEGTHR DLVDAHSDYRDLVTR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0017 | - | - | 100% (575) | ABC transporter, permease/ATP-binding protein |
| M. smegmatis MC2 155 | MSMEG_5661 | - | 8e-34 | 24.79% (605) | ABC transporter ATP-binding protein |
| M. smegmatis MC2 155 | MSMEG_6553 | - | 2e-33 | 26.21% (515) | ABC transporter ATP-binding protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0200 | - | 7e-46 | 28.77% (584) | drugs-transport transmembrane ATP-binding protein ABC |
| M. gilvum PYR-GCK | Mflv_2251 | - | 4e-38 | 26.03% (580) | ABC transporter related |
| M. tuberculosis H37Rv | Rv0194 | - | 1e-45 | 28.08% (584) | drugs-transport transmembrane ATP-binding protein ABC |
| M. leprae Br4923 | MLBr_01113 | - | 1e-30 | 25.05% (523) | putative ABC transporter, ATP-binding component |
| M. abscessus ATCC 19977 | MAB_1414c | - | 7e-37 | 25.83% (515) | ABC transporter ATP-binding protein |
| M. marinum M | MMAR_5223 | - | 4e-46 | 27.42% (569) | drug-transport transmembrane ATP-binding protein ABC |
| M. avium 104 | MAV_1420 | - | 1e-36 | 26.48% (540) | ABC transporter |
| M. thermoresistible (build 8) | TH_4626 | - | 5e-36 | 26.06% (564) | PUTATIVE ABC transporter ATP-binding protein |
| M. ulcerans Agy99 | MUL_4011 | - | 3e-36 | 26.74% (531) | transmembrane ATP-binding protein ABC transporter |
| M. vanbaalenii PYR-1 | Mvan_4441 | - | 3e-37 | 25.61% (531) | ABC transporter, transmembrane region |
CLUSTAL 2.0.9 multiple sequence alignment
MLBr_01113|M.leprae_Br4923 --------------------------------------------------
MUL_4011|M.ulcerans_Agy99 --------------------------------------------------
MAV_1420|M.avium_104 --------------------------------------------------
MAB_1414c|M.abscessus_ATCC_199 --------------------------------------------------
Mvan_4441|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb0200|M.bovis_AF2122/97 MRTNCWWRLSGYVMRHRRDLLLGFGAALAGTVIAVLVPLVTKRVIDDAVA
Rv0194|M.tuberculosis_H37Rv MRTNCWWRLSGYVMRHRRDLLLGFGAALAGTVIAVLVPLVTKRVIDDAIA
MMAR_5223|M.marinum_M MRTNWWGRLSRYVLRYRRDLLLGLFASVVGTAITVMVPLVTKRVIDNAIA
Mflv_2251|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_0017|M.smegmatis_MC2_155 --------------------------------------------------
TH_4626|M.thermoresistible__bu --------------------------------------------------
MLBr_01113|M.leprae_Br4923 --------------------------------------------------
MUL_4011|M.ulcerans_Agy99 --------------------------------------------------
MAV_1420|M.avium_104 --------------------------------------------------
MAB_1414c|M.abscessus_ATCC_199 --------------------------------------------------
Mvan_4441|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb0200|M.bovis_AF2122/97 ADHRPLAPWAVVLVAAAGATYLLTYVRRYYGGRIAHLVQHDLRMDAFQAL
Rv0194|M.tuberculosis_H37Rv ADHRPLAPWAVVLVAAAGATYLLMYVRRYYGGRIAHLVQHDLRMDAFQAL
MMAR_5223|M.marinum_M PDHRPLAPWALVLVAAAVAIYFMTFVRRHYGGRIAHLVQHDLRVDAFATL
Mflv_2251|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_0017|M.smegmatis_MC2_155 --------------------------------------------------
TH_4626|M.thermoresistible__bu --------------------------------------------------
MLBr_01113|M.leprae_Br4923 --------------------------------------------------
MUL_4011|M.ulcerans_Agy99 --------------------------------------------------
MAV_1420|M.avium_104 --------------------------------------------------
MAB_1414c|M.abscessus_ATCC_199 --------------------------------------------------
Mvan_4441|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb0200|M.bovis_AF2122/97 LRWDGRQQDRWSSGQLIVRTTNDLQLVQALLFDVPNVLRHVLTLLLGVAV
Rv0194|M.tuberculosis_H37Rv LRWDGRQQDRWSSGQLIVRTTNDLQLVQALLFDVPNVLRHVLTLLLGVAV
MMAR_5223|M.marinum_M MRWDGRQQDRWSSGQLIVRTTNDLELVQTLLFDLPNVIRHLLTLLLCLAV
Mflv_2251|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_0017|M.smegmatis_MC2_155 --------------------------------------------------
TH_4626|M.thermoresistible__bu --------------------------------------------------
MLBr_01113|M.leprae_Br4923 ----------------------------MTMAT-------APA-TRSCDF
MUL_4011|M.ulcerans_Agy99 ----------------------------MTAALNQRPRGGAPAPTRSRDF
MAV_1420|M.avium_104 ----------------------------MTTTTRPAPP--APA-GRSRDF
MAB_1414c|M.abscessus_ATCC_199 ----------------------------MTRAIG-FRGVQQGPAERSRDF
Mvan_4441|M.vanbaalenii_PYR-1 ----------------------------MTGPLARSMRMAEPPQTRSRDF
Mb0200|M.bovis_AF2122/97 MTWLSVPLALLAVLLVPVIGLIAHRSRRLLAAATHCAQEHKAAVTGVVDA
Rv0194|M.tuberculosis_H37Rv MTWLSVPLALLAVLLVPVIGLIAHRSRRLLAAATHCAQEHKAAVTGVVDA
MMAR_5223|M.marinum_M MAWLSLPLALLVVLLVPLIGLVAHRSRRLLAVATEAAQERNAVVTGVVDA
Mflv_2251|M.gilvum_PYR-GCK ----------------------------------------------MCDS
MSMEG_0017|M.smegmatis_MC2_155 -----------------------------------------MADTTRTDL
TH_4626|M.thermoresistible__bu --------------------------------------------------
MLBr_01113|M.leprae_Br4923 YCTIRRLLKQLVPQRRLSLTVITLG-------------------------
MUL_4011|M.ulcerans_Agy99 WGSATRLVKRLAPQRRRSLAVIALG-------------------------
MAV_1420|M.avium_104 WGSAARLVKQLAPQRRTAIAVITLG-------------------------
MAB_1414c|M.abscessus_ATCC_199 RGTAIRMVKRLAPQRFLTATVITLS-------------------------
Mvan_4441|M.vanbaalenii_PYR-1 TGSALRLFRRLTPQRGMTVAVMLLG-------------------------
Mb0200|M.bovis_AF2122/97 AVCGIRVVKAFGQEERETVKLVMASRALYAAQLRVARLNAHFGPLLQTLP
Rv0194|M.tuberculosis_H37Rv AVCGIRVVKAFGQEERETVKLVTASRALYAAQLRVARLNAHFGPLLQTLP
MMAR_5223|M.marinum_M AVSGIHVVKAFGQQSQETVKLTTAGRALYAARVRVARLNAYFGPLLQSLP
Mflv_2251|M.gilvum_PYR-GCK SGMLWELLRRYARPYRPLLAVVAAL-------------------------
MSMEG_0017|M.smegmatis_MC2_155 SWTGVRVLRRTVSRN---LKWLTSG-------------------------
TH_4626|M.thermoresistible__bu --MIRTLLRLVPAEKRGAVAG-----------------------------
:.:
MLBr_01113|M.leprae_Br4923 --------------------------------------------------
MUL_4011|M.ulcerans_Agy99 --------------------------------------------------
MAV_1420|M.avium_104 --------------------------------------------------
MAB_1414c|M.abscessus_ATCC_199 --------------------------------------------------
Mvan_4441|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb0200|M.bovis_AF2122/97 ALGQMAVFALGGWMAAQGSITVGTFVAFWACLTLLARPACDLAGMLTIAQ
Rv0194|M.tuberculosis_H37Rv ALGQMAVFALGGWMAAQGSITVGTFVAFWACLTLLARPACDLAGMLTIAQ
MMAR_5223|M.marinum_M AFGQMAVLAVGGWMAAQGTITVGTFVAFWSCLTLVSRPACDLAGMLTIAQ
Mflv_2251|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_0017|M.smegmatis_MC2_155 --------------------------------------------------
TH_4626|M.thermoresistible__bu --------------------------------------------------
MLBr_01113|M.leprae_Br4923 --------------------------------------------------
MUL_4011|M.ulcerans_Agy99 --------------------------------------------------
MAV_1420|M.avium_104 --------------------------------------------------
MAB_1414c|M.abscessus_ATCC_199 --------------------------------------------------
Mvan_4441|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb0200|M.bovis_AF2122/97 QARAGAVRVLELIDSRPTLVDGTKPLSLEARLSLEFQRVSFGYVADRPVL
Rv0194|M.tuberculosis_H37Rv QARAGAVRVLELIDSRPTLVDGTKPLSPEARLSLEFQRVSFGYVADRPVL
MMAR_5223|M.marinum_M QARTGAMRVFELIDSRPTLVDGTKQLPSSTPVSLAFEQASFGYAAEHPVL
Mflv_2251|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_0017|M.smegmatis_MC2_155 --------------------------------------------------
TH_4626|M.thermoresistible__bu --------------------------------------------------
MLBr_01113|M.leprae_Br4923 -------ITGTAIGIIVPWVLG----------------------------
MUL_4011|M.ulcerans_Agy99 -------IVGTAIGVAVPRILG----------------------------
MAV_1420|M.avium_104 -------IAGTVIGVMVPRILG----------------------------
MAB_1414c|M.abscessus_ATCC_199 -------MIGIAIGVIGPRILG----------------------------
Mvan_4441|M.vanbaalenii_PYR-1 -------VGGIAIGVIGPRILG----------------------------
Mb0200|M.bovis_AF2122/97 REISLSVRAGETLAVVGAPGSGKSTLASLATRCYDVTQGAVRIGGQDVRE
Rv0194|M.tuberculosis_H37Rv REISLSVRAGETLAVVGAPGSGKSTLASLATRCYDVTQGAVRIGGQDVRE
MMAR_5223|M.marinum_M RGIDLSVRPGETLAVVGPPGSGKSTLALLAMRCYDVTAGAVRVGGHDVRD
Mflv_2251|M.gilvum_PYR-GCK -------QVVSTMATLYLPTVN----------------------------
MSMEG_0017|M.smegmatis_MC2_155 -------TTLIALHQLCEVSVP----------------------------
TH_4626|M.thermoresistible__bu -------YAVLTLLSVLLRAVG----------------------------
.:
MLBr_01113|M.leprae_Br4923 -------------HTTDLLFNGVIGRQLPKG---ISKTQAVAAARTRGDN
MUL_4011|M.ulcerans_Agy99 -------------HAADLLFNGVIGRQLPAG---ITKAQAIAGARARGDN
MAV_1420|M.avium_104 -------------HATDLLFNGVVGRQLPAG---ISKAQAVAAARSRGQN
MAB_1414c|M.abscessus_ATCC_199 -------------HATDLLFNGVIGRQLPAG---QSREQAVETARARGDG
Mvan_4441|M.vanbaalenii_PYR-1 -------------HATDLLFNGVIGRQLPAG---LTKEQAVEAARARGDG
Mb0200|M.bovis_AF2122/97 LTLDSLRSAIGLVPEDAVLFSGTIGANIAYGRPDATPEQIATAARAAHIE
Rv0194|M.tuberculosis_H37Rv LTLDSLRSAIGLVPEDAVLFSGTIGANIAYGRPDATPEQIATAARAAHIE
MMAR_5223|M.marinum_M LTLDSLRSAIGLVPEQAILFSGTIGENISYGRSNVTLEQITAAARAAHID
Mflv_2251|M.gilvum_PYR-GCK --------------------AAIIDDGVAQG----DLDRIVRLGAVMLAV
MSMEG_0017|M.smegmatis_MC2_155 -----------------VLIGIIVDRAVATG----SVEAILRWIAVLAAL
TH_4626|M.thermoresistible__bu ----------------AVLLIPLLAALFSDT-----PSDAWLWLGWLTAV
: ..
MLBr_01113|M.leprae_Br4923 ALADLLSG----------MNLVPGQ-------------------------
MUL_4011|M.ulcerans_Agy99 TFAELLSG----------MKVTPGQ-------------------------
MAV_1420|M.avium_104 TFADLLSG----------MNVVPGR-------------------------
MAB_1414c|M.abscessus_ATCC_199 QFAQMLSG----------MNVIPGQ-------------------------
Mvan_4441|M.vanbaalenii_PYR-1 TFADLLSG----------MDVVPGQ-------------------------
Mb0200|M.bovis_AF2122/97 EFVNTLPDGYQTAVGARGLTLSGGQRQRIALARALLHQPRLLIMDDPTSA
Rv0194|M.tuberculosis_H37Rv EFVNTLPDGYQTAVGARGLTLSGGQRQRIALARALLHQPRLLIMDDPTSA
MMAR_5223|M.marinum_M EFVNTLPDGYATPVGAQGLTLSGGQRQRIALARALVGNPRLLIMDEPTSA
Mflv_2251|M.gilvum_PYR-GCK TAVQV---------------------------------------------
MSMEG_0017|M.smegmatis_MC2_155 FVVLT---------------------------------------------
TH_4626|M.thermoresistible__bu TLAGWVTD------------------------------------------
.
MLBr_01113|M.leprae_Br4923 ---------------------GVDFVAVGRTLGLALSLYLVYT-------
MUL_4011|M.ulcerans_Agy99 ---------------------GVDFGAVVRTLALALALYLIAS-------
MAV_1420|M.avium_104 ---------------------GVDFGAVARTLALALLLYLVSA-------
MAB_1414c|M.abscessus_ATCC_199 ---------------------GVDFHAIGMTLALALSLYLIAG-------
Mvan_4441|M.vanbaalenii_PYR-1 ---------------------GVDFGAVGRTLALALALYLVAA-------
Mb0200|M.bovis_AF2122/97 VDAVIECGIQEVLREAIADRTAVIFTRRRSMLTLADRVAVLDSGRLLDVG
Rv0194|M.tuberculosis_H37Rv VDAVIECGIQEVLREAIADRTAVIFTRRRSMLTLADRVAVLDSGRLLDVG
MMAR_5223|M.marinum_M VDAVIEASIQDVLREVLADRTAVIFTRRRSMLSLADRVAVLDSGHLLDIG
Mflv_2251|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_0017|M.smegmatis_MC2_155 --------------------------------------------------
TH_4626|M.thermoresistible__bu --------------------------------------------------
MLBr_01113|M.leprae_Br4923 --------------------------------------------------
MUL_4011|M.ulcerans_Agy99 --------------------------------------------------
MAV_1420|M.avium_104 --------------------------------------------------
MAB_1414c|M.abscessus_ATCC_199 --------------------------------------------------
Mvan_4441|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb0200|M.bovis_AF2122/97 TPDEVWERCPRYRELLSPAPDLADDLVVAERSPVCRPVAGLGTKAAQHTN
Rv0194|M.tuberculosis_H37Rv TPDEVWERCPRYRELLSPAPDLADDLVVAERSPVCRPVAGLGTKAAQHTN
MMAR_5223|M.marinum_M TPEQLWGRCSRYRELLSPATDPLRSLAFEDGVPEPESEP-----EAIDVA
Mflv_2251|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_0017|M.smegmatis_MC2_155 --------------------------------------------------
TH_4626|M.thermoresistible__bu --------------------------------------------------
MLBr_01113|M.leprae_Br4923 --------------------------------------------------
MUL_4011|M.ulcerans_Agy99 --------------------------------------------------
MAV_1420|M.avium_104 --------------------------------------------------
MAB_1414c|M.abscessus_ATCC_199 --------------------------------------------------
Mvan_4441|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb0200|M.bovis_AF2122/97 VHNPGPHDHPPGPDPLRRLLREFRGPLALSLLLVAVQTCAGLLPPLLIRH
Rv0194|M.tuberculosis_H37Rv VHNPGPHDHPPGPDPLRRLLREFRGPLALSLLLVAVQTCAGLLPPLLIRH
MMAR_5223|M.marinum_M ADATGPSDHSPKPDLLRRLLHDFRGPLIVSLLLVALETGAGLLPPLLIRH
Mflv_2251|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_0017|M.smegmatis_MC2_155 --------------------------------------------------
TH_4626|M.thermoresistible__bu --------------------------------------------------
MLBr_01113|M.leprae_Br4923 -----------------------------LLTWAQARLLNVTVQRIMFAL
MUL_4011|M.ulcerans_Agy99 -----------------------------LLIWGQARLLNVTVQRTVAAL
MAV_1420|M.avium_104 -----------------------------LLIWVQARLLNRTVQRTMVAL
MAB_1414c|M.abscessus_ATCC_199 -----------------------------MLAWVQARLLNVTVQRTVVAL
Mvan_4441|M.vanbaalenii_PYR-1 -----------------------------LMVWLQALLLNIVVQRTMVAL
Mb0200|M.bovis_AF2122/97 GIDVGIRRHVLSALWWAALAGTATVVIRWVVQWGSAMVAGYTGEQVLFRL
Rv0194|M.tuberculosis_H37Rv GIDVGIRRHVLSALWWAALAGTATVVIRWVVQWGSAMVAGYTGEQVLFRL
MMAR_5223|M.marinum_M GIDVGIRQHVLTALWWAALAGAAIVAIRLVAQWGSAVVAGTAGEKALFRL
Mflv_2251|M.gilvum_PYR-GCK -----------------------------VCAVGAVYFGSRASMGVGRDL
MSMEG_0017|M.smegmatis_MC2_155 -----------------------------VVYRFGARLLMFAIARESHLL
TH_4626|M.thermoresistible__bu --------------------------------TNTARLGFDLGFAVLSRT
. .
MLBr_01113|M.leprae_Br4923 RSDVEDKVHRLPLSYCDTRQRGELLSRVTNDIDNLQSSLSITLSQLLTSL
MUL_4011|M.ulcerans_Agy99 RADVEHKLHRLPLSYFDGRQRGELLSRVTNDIDNIQSSLSMTISQLVTAI
MAV_1420|M.avium_104 RSAVEDKVHRLPLAYFDGRQRGELLSRVTNDIDNIQSSLSMTISQLLTSV
MAB_1414c|M.abscessus_ATCC_199 RTEVENKIHRLPLSYFDSRQRGEILSRVTNDVDNIQTSLQMSINQLLSSM
Mvan_4441|M.vanbaalenii_PYR-1 RADVEDKVHRLPLRYFDSRQRGEVLSRVTNDVDNLQQSLSMSITQLLTSV
Mb0200|M.bovis_AF2122/97 RSVVFAHAQRLGLDAFEDDGDAQIVTAVTADVEAIVAFLRTGLVVAVISV
Rv0194|M.tuberculosis_H37Rv RSVVFAHAQRLGLDAFEDDGDAQIVTAVTADVEAIVAFLRTGLVVAVISV
MMAR_5223|M.marinum_M RSLVFAHAQRLDLDAFEDNGDSQIITAVTADVDAIVAFLRTGLVIAIVSL
Mflv_2251|M.gilvum_PYR-GCK RSSLFHHVTGFSAEETARFGAPSLLTRTTNDVQQIQLLVQLSATMLITAP
MSMEG_0017|M.smegmatis_MC2_155 RVESSAKILDP-LGIETDYKVGELLSISSDDADEVSYLLDY-VPRIVGAV
TH_4626|M.thermoresistible__bu QHDMADRLPNVAMSWFTPDNTATARQAIAATGPELAGLVVNLLTPLIGAA
: : : : : : :
MLBr_01113|M.leprae_Br4923 LTVVAVLVVMVSVSPLLALVALLTVPMSLLATRAIAQRSQQLFVAQWTSA
MUL_4011|M.ulcerans_Agy99 LTVVAVLSMMVWISPLLALITLLTVPLSLLVTRAITRRSQRLFVAHWTST
MAV_1420|M.avium_104 LTVLTVLAMMLSISPLLAGITLLTVPLSLLATRVIVRRSQRLFVAQWTSV
MAB_1414c|M.abscessus_ATCC_199 LTLVAVLAMMLSISPLLAVITLATVPLSLWVTRTIARRSQRLFVAQWANT
Mvan_4441|M.vanbaalenii_PYR-1 LTVIAVLVMMLTISPLLTLLTVVTVPLSLWVTRSIAKRSRTLFVAQWTNT
Mb0200|M.bovis_AF2122/97 VTLVGILVALLAIRARLVLLIFTTMPVLALATWQFRRASNWTYRRARHRL
Rv0194|M.tuberculosis_H37Rv VTLVGILVALLAIRARLVLLIFTTMPVLALATWQFRRASNWTYRRARHRL
MMAR_5223|M.marinum_M VTAVGILAALLAINAKLALLIFATLPMLGLATWQFRRASSWTYRQARQRL
Mflv_2251|M.gilvum_PYR-GCK IMCVGGIFMAIHQDAGLSWLLLVAVPVLALANYWIVSHLLPIFRRVQGQI
MSMEG_0017|M.smegmatis_MC2_155 VGTVVCGAVLLSIHLPLGLMVLIGVPVVVFGLQLTAPMIARRVEDQQAEI
TH_4626|M.thermoresistible__bu LLPAAIGVALLFVSVPLGLAALAGVAVLFGALALSGRLSRAADKVAGETN
: : * . :.:
MLBr_01113|M.leprae_Br4923 GRLNAHIEETYSGLTVVKTFGHQTAAREQFRNVNNDVYQASFSAQFFSGL
MUL_4011|M.ulcerans_Agy99 GRLNAHIEETYSGFTVVKTFGHQAAAREQFHNLNDDVYQASFGAQLLSAL
MAV_1420|M.avium_104 GRLNAHIEETYSGFTVVQTFGHRAAARDRFRALNDEVYRASFGAQFFSGL
MAB_1414c|M.abscessus_ATCC_199 GKLNAHIEETYSGFTIVKTYGHRAEAEAIFADRNAEVYRSAFGAQFFSGL
Mvan_4441|M.vanbaalenii_PYR-1 GRLNAHIEETYSGFTVVKTFGHRAHAEDQFRQLNDDVYHASFGAQFLSGL
Mb0200|M.bovis_AF2122/97 GTVTATLREYAAGLRIAQAFRAEYRGLQSYFAHSDDYRRLGVRGQRLLAL
Rv0194|M.tuberculosis_H37Rv GTVTATLREYAAGLRIAQAFRAEYRGLQSYFAHSDDYRRLGVRGQRLLAL
MMAR_5223|M.marinum_M GTVTATLREYSAGLRIAQAYRAEYVGFQTYFAHSDDYRRLRVRGQRLLAL
Mflv_2251|M.gilvum_PYR-GCK DSINRVMREQLTGLRVVRAFAREPFERNRFAEANTELAGSVLEAGRWQAL
MSMEG_0017|M.smegmatis_MC2_155 GRATALATDLISGQRPLQGIGAQANAAARYRVASRRALTATLRAARIQSI
TH_4626|M.thermoresistible__bu SAFTERIIEFARTQQALRAARRVEPARSQVGSALAAQHGAGLRLLTMQIP
. . : : .
MLBr_01113|M.leprae_Br4923 VSPATMFISNLGYVVVAALGGLQVATGHITLGNIQAFIQYVRQFNMPLSQ
MUL_4011|M.ulcerans_Agy99 VQPATTFIGNLGYVAVAVMGGLQVATGQITLGSVQAFIQYVRQFNTPVSQ
MAV_1420|M.avium_104 VAPATAVIGNLGYAAVAVLGGLQVATGQITLGNIQAFIQYVRQFNSPLSQ
MAB_1414c|M.abscessus_ATCC_199 VSPATAFVGNLSYVAVAVVGGLKVASGGLTLGSIQAFSQYVRQFNQPLTQ
Mvan_4441|M.vanbaalenii_PYR-1 VSPATIFIGNLSYAAVAVVGGLQVATGQITLGSIQAFIQYVRQFNQPLTQ
Mb0200|M.bovis_AF2122/97 YYPFVALLCSLATTLVLLDGAREVRAGVISVGALVTYLLYIELLYTPIGE
Rv0194|M.tuberculosis_H37Rv YYPFVALLCSLATTLVLLDGAREVRAGVISVGALVTYLLYIELLYTPIGE
MMAR_5223|M.marinum_M YFPLVPLTCSLATTLVLFEGGRDVQAGVLSVGALVTYLLYVEMLFAPVDK
Mflv_2251|M.gilvum_PYR-GCK MLPVTTLVINVSSVALIWFGGMRIDAGEMQVGSLIAFLSYFMQILMSVLM
MSMEG_0017|M.smegmatis_MC2_155 HSGAAAAAGALAAMAVAVVAAYFAIRGSMTVGQLITVIGLAQFLIEPFSL
TH_4626|M.thermoresistible__bu GQVLFSLAGQVALIGFAGMAVWLTVRGQLGVPEAIALIVVLVRYLEPFAA
:. . . * : : : ..
MLBr_01113|M.leprae_Br4923 VAGIYNTLQSGLASAERVFDLLDEPEELPDPMLALPPPH-----GQVPRI
MUL_4011|M.ulcerans_Agy99 VAAMYNSLQSGVASAERVFELLDEPEEAADPASALQPPVS--RTGRAPAL
MAV_1420|M.avium_104 LAGMYNTLQSGVASAERVFALLDEPEEPPDAPPEEKPTAPG-PAGRDAGG
MAB_1414c|M.abscessus_ATCC_199 VAAMYNTLQSGLASAERVFELLDADEETPDP---LAAATAPTGSVR----
Mvan_4441|M.vanbaalenii_PYR-1 IAGMYNTMQSGIASAERVFDLLDAEEEPSEPDRRLAPDSPTVLPARDGRP
Mb0200|M.bovis_AF2122/97 LAQMFDDYQRAAVAAGRIRSLLSTRTPSSPAARPVGTLRG----------
Rv0194|M.tuberculosis_H37Rv LAQMFDDYQRAAVAAGRIRSLLSTRTPSSPAARPVGTLRG----------
MMAR_5223|M.marinum_M LSQMFDEYQRAAVAVGRIRSLLNTPTAFSPSAAPVGTLRG----------
Mflv_2251|M.gilvum_PYR-GCK ATFILVIIPRASVCAERITEVLSTEPAITSSPSAASPDTVAG--------
MSMEG_0017|M.smegmatis_MC2_155 LAVVPSWVAEARASANRVARVLSAPTRHSPVFAADPRDAA----------
TH_4626|M.thermoresistible__bu IADLAPALETTRATLNRIQAVLDAPTLPAGRRRLDRTGAAP---------
: : . *: :*. .
MLBr_01113|M.leprae_Br4923 NGRVEFQQVSFAYRT-GTPVIDDLSMVVEPGSTVAIVGPTGAGKTTLVNL
MUL_4011|M.ulcerans_Agy99 TGRVEFERVNFAYHP-GHPVIHDLSLVAEPGSTVAIVGPTGAGKTTLVNL
MAV_1420|M.avium_104 GGRVEFAHVSFAYRP-GIRVIDDLSLVAEPGSTVAIVGPTGAGKTTLVNL
MAB_1414c|M.abscessus_ATCC_199 ---VEFEDISFGYSP-GQPVIEGLSLRVEPGQTVAIVGPTGAGKTTLVNL
Mvan_4441|M.vanbaalenii_PYR-1 GGRVEFDRVWFGYEH-GAPVIEDLSLVAEPGTTVAIVGPTGAGKTTLVNL
Mb0200|M.bovis_AF2122/97 --EVVFDAVHYSYRTREVPALAGINLRIPAGQTVVFVGSTGSGKSTLIKL
Rv0194|M.tuberculosis_H37Rv --EVVFDAVHYSYRTREVPALAGINLRIPAGQTVVFVGSTGSGKSTLIKL
MMAR_5223|M.marinum_M --EIEFDAVHFRYPTRDAPALAGINLRIPAGQTVVFVGSTGSGKSTLMKL
Mflv_2251|M.gilvum_PYR-GCK --EIRFDRATFSYAGADRPVLQDVSFTARPGTTTAIVGSTGSGKSTLISL
MSMEG_0017|M.smegmatis_MC2_155 --------ARLSVRNATHAGLKNLSFDVEPGEFVAVLTSDVRDAGALIDL
TH_4626|M.thermoresistible__bu --SIEFDDVRFSYGD--EVVLDGVSFTLRPGNTTAIVGPSGSGKTTILSL
: .:.: .* ...: . . :::.*
MLBr_01113|M.leprae_Br4923 LMRFYDVDS-GQILIDGVDITTVSRHALRSRIGMVLQDAWLFDGTIAENI
MUL_4011|M.ulcerans_Agy99 LMRFYEVDS-GRILVDGIDITTVSRQSLRSHIGMVLQDTWLFDGTISENI
MAV_1420|M.avium_104 LMRFYDVDA-GRISIDGVDIATMDRRALRSRIGMVLQDTWLFDGTIAENI
MAB_1414c|M.abscessus_ATCC_199 LMRFYEVDS-GRILLDGIDVSTMTRHDLRSRMGMVLQDTWLFGGTIVENI
Mvan_4441|M.vanbaalenii_PYR-1 LMRFYDVDS-GRILLDGVDISAVSRASLRSRIGMVLQDTWLFAGTVYENI
Mb0200|M.bovis_AF2122/97 VARFYDPTH-GTVRVDGCDLREFDVDGYRNRLGIVTQEQYVFAGTVRDAI
Rv0194|M.tuberculosis_H37Rv VARFYDPTH-GTVRVDGCDLREFDVDGYRNRLGIVTQEQYVFAGTVRDAI
MMAR_5223|M.marinum_M VSRFYDPTD-GIIRVDGCDLREFDIDGYRSRLSIVAQEPYLFAGTVRDAI
Mflv_2251|M.gilvum_PYR-GCK ICRLYDVTA-GAISVDGIDVRDFDIEKLWTVIGLVPQRGYLFSGTISDNL
MSMEG_0017|M.smegmatis_MC2_155 LSGYQRAEDKGTVLVGGRRLDQIPLKERREHLLVEHHLSSLFSGTLETNL
TH_4626|M.thermoresistible__bu IAGLQQPAS-GRVLLDGVDVTTLDPEARRAAVSVVFQHPYLFDGTLRDNV
: * : :.* : . : : : :* **: :
MLBr_01113|M.leprae_Br4923 AYGRPQ---ASEDEVMEAAKAAYVDRFVHTLSAGYQTRVSGDGDNISAGE
MUL_4011|M.ulcerans_Agy99 AYGRPE---ASPDDIIQAAKAAYVDRFVHMLPASYQTRISGDGSNISAGE
MAV_1420|M.avium_104 GYGRPG---AGDDEIVAAARAAYVDRFVQNLPDGYHTRVSGDGGNLSAGE
MAB_1414c|M.abscessus_ATCC_199 AYGRPG---ASQEEILEAARAAYVDRFVRTLPDGYDTKIADDGGNISAGE
Mvan_4441|M.vanbaalenii_PYR-1 AYGRPE---AGRDEVIDAAKAAYVDRFVHTLPDGYETRIDDGGTNISAGE
Mb0200|M.bovis_AF2122/97 AYGRPD---ATDAQVERAAREVGAHPMITALDNGYLHQVTAGGRNLSAGQ
Rv0194|M.tuberculosis_H37Rv AYGRPD---ATDAQVERAAREVGAHPMITALDNGYLHQVTAGGRNLSAGQ
MMAR_5223|M.marinum_M AYGRPD---ATDAQVERAAREVGAHPMIAALDGGYQHEVAAGGRNLSAGQ
Mflv_2251|M.gilvum_PYR-GCK QFGAPPGHVATEDQMWEALRVACADDFVAGHPDGLLMRVAQGGMNFSGGQ
MSMEG_0017|M.smegmatis_MC2_155 NVTGTDPR-RGRVSVDDALQASCAVDVVDLHPDGLAHAVVERGASLSGGQ
TH_4626|M.thermoresistible__bu LVGDPE---ADPDDVTAAMRLARVDELLDRLPDGDATVVGEGGTALSGGE
. .: * : . .: . : * :*.*:
MLBr_01113|M.leprae_Br4923 KQLITIARAFLARPQLLILDEATSSIDTRTEALIARATHDLLQ--DRTSF
MUL_4011|M.ulcerans_Agy99 KQLITIARAFLARPQLLILDEATSSVDTRTELLIARATAELRR--DRTSF
MAV_1420|M.avium_104 RQLITIARAFLARPQLLILDEATSSVDTRTEALIAHATRELRR--DRTSF
MAB_1414c|M.abscessus_ATCC_199 KQLITIARAFLARPQLLILDEATSSVDTRTELRIQRAMAELRR--DRTSF
Mvan_4441|M.vanbaalenii_PYR-1 KQLITIARAVLAQPQLLILDEATSSVDTRTEVLIQHAMGRLRR--ERTSF
Mb0200|M.bovis_AF2122/97 LQLLALARARLVDPDILLLDEATVALDPATEAVVQRATLTLAA--RRTTL
Rv0194|M.tuberculosis_H37Rv LQLLALARARLVDPDILLLDEATVALDPATEAVVQRATLTLAA--RRTTL
MMAR_5223|M.marinum_M LQLLALARARLVDSDILLLDEATVALDPATEALVHWATLGLAA--DRTTL
Mflv_2251|M.gilvum_PYR-GCK RQRLAIARAVIRKPVIYLFDDAFSALDVHTDARVRERVREASA--GSTVI
MSMEG_0017|M.smegmatis_MC2_155 RQRWTLARALLADPAVLVLHDPTTAIDTVTEQVIADGIRRLRTRAGRTTV
TH_4626|M.thermoresistible__bu RQRVSIARALLKPAPVLLVDEATSALDNANEAAVVDALTADPR--PRTRV
* ::*** : . : :..:. ::* .: : * .
MLBr_01113|M.leprae_Br4923 IIAHHLPTIRDADHILVVAAGKIVEQGSHAKLLARRGAYYRMTQA-----
MUL_4011|M.ulcerans_Agy99 IIAHRLSTIRDADQILVVQAGQIVEHGTHAELLANRGAYYAMTRA-----
MAV_1420|M.avium_104 IIAHRLSTIRDADRIAVIEAGRIFEQGTHAELLARRGVYYAMTQA-----
MAB_1414c|M.abscessus_ATCC_199 IIAHRLSTIRDADRIVVLDGGRVTESGTHTELLARHGAYFAMTQS-----
Mvan_4441|M.vanbaalenii_PYR-1 IIAHRLSTIRDADLILVMQAGRIVERGTHEELLARGGEYAAMVNR-----
Mb0200|M.bovis_AF2122/97 IVAHGLAIAEHADRIVVLEHGTVVEDGAHTELLAAGGHYSRLWAAHTRLC
Rv0194|M.tuberculosis_H37Rv IVAHGLAIAEHADRIVVLEHGTVVEDGAHTELLAAGGHYSRLWAAHTRLC
MMAR_5223|M.marinum_M IIAHELAIAEFVDRIVVLEQGTIVEDGTHVELLAAGGRYAALWAAHSRVG
Mflv_2251|M.gilvum_PYR-GCK IVSQRISTVSGADLIVVLDDGRMVGAGTHAELLDSCSAYREFADSQSVSA
MSMEG_0017|M.smegmatis_MC2_155 VLTSSPALLAAADRVLLVIDGRLDSEGTHRDLVDAHSDYRDLVTR-----
TH_4626|M.thermoresistible__bu IVAHRLASIRHADRVLFVEAGRVVEDGAIDELLAAGGRFAQFWAQQQAAS
::: . .* : .: * : *: .*: . : :
MLBr_01113|M.leprae_Br4923 ------------------------
MUL_4011|M.ulcerans_Agy99 ------------------------
MAV_1420|M.avium_104 ------------------------
MAB_1414c|M.abscessus_ATCC_199 ------------------------
Mvan_4441|M.vanbaalenii_PYR-1 ------------------------
Mb0200|M.bovis_AF2122/97 SPEITQLQCIDA------------
Rv0194|M.tuberculosis_H37Rv SPEITQLQCIDA------------
MMAR_5223|M.marinum_M RPSPSDDRPIPTELLVHSPDTDVL
Mflv_2251|M.gilvum_PYR-GCK GDR---------------------
MSMEG_0017|M.smegmatis_MC2_155 ------------------------
TH_4626|M.thermoresistible__bu EWAIGSTAR---------------