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M. gilvum PYR-GCK Mflv_3730 (fmt)

annotation: methionyl-tRNA formyltransferase
coordinates: 3978566 - 3979498
length: 310

RLVFAGTPEPALPSLQRLIDSARHDVIAVLTRPDAAAGRRGRPSPSPVAELAAAHGIPVLKPPRPNSEEF
VAELAALAPDCCAVVAYGALLREELLAVPALGWVNLHFSVLPAWRGAAPVQAALAAGDEVTGATTFQIEL
SLDSGPVYGVVTETIRPTDTAGDLLGRLAESGAGLLEATMDGIEDGTLTAVPQPAEGVSIAPKVSVDDAR
IRWELPAHVVDRRIRSVTPNPGAWTMAGELRIKVGPVTVPDDGPKDLEPGEIRVGKKHVHVGTATDAVLL
GTVQPPGKKSMNAADWARGARAEDIRRAR*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_3730fmt-100% (310)methionyl-tRNA formyltransferase
M. gilvum PYR-GCKMflv_1874purN8e-0629.82% (114) phosphoribosylglycinamide formyltransferase
M. gilvum PYR-GCKMflv_5090purU1e-0526.67% (105) formyltetrahydrofolate deformylase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1441fmt1e-12371.06% (311) methionyl-tRNA formyltransferase
M. tuberculosis H37RvRv1406fmt1e-12371.06% (311) methionyl-tRNA formyltransferase
M. leprae Br4923MLBr_00552fmt1e-11868.35% (316) methionyl-tRNA formyltransferase
M. abscessus ATCC 19977MAB_2811c-1e-11970.72% (304) methionyl-tRNA formyltransferase
M. marinum MMMAR_2215fmt1e-12973.16% (313) methionyl-tRNA formyltransferase Fmt
M. avium 104MAV_3372fmt1e-12972.61% (314) methionyl-tRNA formyltransferase
M. smegmatis MC2 155MSMEG_3064fmt1e-13877.02% (309) methionyl-tRNA formyltransferase
M. thermoresistible (build 8)TH_1529fmt1e-13574.92% (315) PROBABLE METHIONYL-TRNA FORMYLTRANSFERASE FMT
M. ulcerans Agy99MUL_1802fmt1e-12972.99% (311) methionyl-tRNA formyltransferase
M. vanbaalenii PYR-1Mvan_2687fmt1e-15687.74% (310) methionyl-tRNA formyltransferase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3730|M.gilvum_PYR-GCK          --MRLVFAGTPEPALPSLQRLIDSARHDVIAVLTRPDAAAGRRGRPSPSP
Mvan_2687|M.vanbaalenii_PYR-1       --MRLVFAGTPEPALPSLQRLIDSDRHEVIAVMTRPDAVAGRRGRPSPSP
Mb1441|M.bovis_AF2122/97            --MRLVFAGTPEPALASLRRLIESPSHDVIAVLTRPDAASGRRGKPQPSP
Rv1406|M.tuberculosis_H37Rv         --MRLVFAGTPEPALASLRRLIESPSHDVIAVLTRPDAASGRRGKPQPSP
MLBr_00552|M.leprae_Br4923          MLVRLVFAGTPESALPALCRLIDSPRHDVIAVLTRPDAASGRRGKPEPSP
MAV_3372|M.avium_104                MPVRLVFAGTPEPALPALRRLLDSPRHEVIAVLTRPDAASGRRGKPEPSP
MMAR_2215|M.marinum_M               --MRLVFAGTPETALPALHQLIDSPRHDVIAVLTRPDAASGRRGKPEPSP
MUL_1802|M.ulcerans_Agy99           --MRLVFAGTPETALPALHQLIDSPRHDVIAVLTRPDAASGRRGKPEPSP
MSMEG_3064|M.smegmatis_MC2_155      --MRLVFAGTPEPALPSLRRLIESPRHDVVAVLTRPDAAAGRRGKPRPSP
TH_1529|M.thermoresistible__bu      --MRLVFAGTPEAALPSLRRLIDXXRHEVVAVLTRPDAAAGRRARPAPSP
MAB_2811c|M.abscessus_ATCC_199      --MRIVFAGTPAPALPSLERLLAS-RHEVVAVLTRPDARAGRGRASASSP
                                      :*:****** .**.:* :*:    *:*:**:***** :**   . .**

Mflv_3730|M.gilvum_PYR-GCK          VAELAAAHGIPVLKPPRPNSEEFVAELAALAPDCCAVVAYGALLREELLA
Mvan_2687|M.vanbaalenii_PYR-1       VAQLAAAHGIPVLKPARPNSGEFVAELSALSPDCCAVVAYGALLGDALLA
Mb1441|M.bovis_AF2122/97            VAREAAERGIPVLRPSRPNSAEFVAELSDLAPECCAVVAYGALLGGPLLA
Rv1406|M.tuberculosis_H37Rv         VAREAAERGIPVLRPSRPNSAEFVAELSDLAPECCAVVAYGALLGGPLLA
MLBr_00552|M.leprae_Br4923          VAREALDRGIPLLRPARPNSPVFVSELSEWAPECCVVVAYGALLGSPLLA
MAV_3372|M.avium_104                VAREALDRGIPVLRPARPNSPEFVAELAQLAPDCCAVVAYGALLRDELLA
MMAR_2215|M.marinum_M               VARAALERDIPVLRPSRPNSAEFVAELSELAPQCCAVVAYGALLGDALLG
MUL_1802|M.ulcerans_Agy99           VARAALERGIPVLRPSRPNSAEFVAELSELAPQCCAVVAYGALLGDALLG
MSMEG_3064|M.smegmatis_MC2_155      VAQLALEHGIPLLRPDRPNSDEFVAELTELAPDCCAVVAYGALLSQRLLA
TH_1529|M.thermoresistible__bu      VAKLASEHGIPVLRPPSPNTDEFIAELTELAPDCCPVVAYGALLSERLLA
MAB_2811c|M.abscessus_ATCC_199      VAALAREHGVAVLTPARPNEPEFVRELAQLDVDCCAVVAYGALLKPELLA
                                    **  *  :.:.:* *  **   *: **:    :** ********   **.

Mflv_3730|M.gilvum_PYR-GCK          VPALGWVNLHFSVLPAWRGAAPVQAALAAGDEVTGATTFQIELSLDSGPV
Mvan_2687|M.vanbaalenii_PYR-1       VPAHGWVNLHFSVLPAWRGAAPVQAALAAGDEVTGATTFQIERSLDSGPV
Mb1441|M.bovis_AF2122/97            VPPHGWVNLHFSLLPAWRGAAPVQAAIAAGDTITGATTFQIEPSLDSGPI
Rv1406|M.tuberculosis_H37Rv         VPPHGWVNLHFSLLPAWRGAAPVQAAIAAGDTITGATTFQIEPSLDSGPI
MLBr_00552|M.leprae_Br4923          VPPRGWVNLHFSLLPAWRGAAPVQAAIAAGDTITGATTFQIEPSLDSGPV
MAV_3372|M.avium_104                VPPHGWINLHFSLLPAWRGAAPVQAAIAAGDTITGATTFRIEPALDSGPI
MMAR_2215|M.marinum_M               VPPQGWVNLHFSLLPAWRGAAPVQAAIAAGDAVTGATTFQIEPSLDSGPV
MUL_1802|M.ulcerans_Agy99           VPPQGWVNLHFSLLPAWRGAAPVQAAIAAGDAVTGATTFQIEPSLDSGPV
MSMEG_3064|M.smegmatis_MC2_155      VPRHGWINLHFSLLPAWRGAAPVQAAIAAGDTVTGATTFQIEPALDSGPV
TH_1529|M.thermoresistible__bu      VPRHGWVNLHFSLLPAWRGAAPVQAAIAAGDTVTGASTFRIEPALDSGPI
MAB_2811c|M.abscessus_ATCC_199      VPRLGWVNLHFSLLPAWRGAAPVQASIAAGDEITGATTFLIEPALDSGPV
                                    **  **:*****:************::**** :***:** ** :*****:

Mflv_3730|M.gilvum_PYR-GCK          YGVVTETIRPTDTAGDLLGRLAESGAGLLEATMDGIEDGTLTAVPQPAEG
Mvan_2687|M.vanbaalenii_PYR-1       YGVVTETIRPTDTAGDLLERLSVSGAGLLEATMDGIEDGTLTAVPQPPEG
Mb1441|M.bovis_AF2122/97            YGVVTEVIQPTDTAGDLLKRLAVSGAALLSTTLDGIADQRLTPRPQPADG
Rv1406|M.tuberculosis_H37Rv         YGVVTEVIQPTDTAGDLLKRLAVSGAALLSTTLDGIADQRLTPRPQPADG
MLBr_00552|M.leprae_Br4923          YGVVTETIQPTDTAGDLLERLAVSGATLLSSTLDGIADAILTPRQQPVDG
MAV_3372|M.avium_104                YGVVTEAIRPTDTAGELLARLAVSGAELLSATLDGIADSTLTPRPQPAEG
MMAR_2215|M.marinum_M               YGVVTETIRPTDTAGDLLGRLAVSGAELLSATLDGIAEGALTARPQPADG
MUL_1802|M.ulcerans_Agy99           YGVVTETIRPTDTAGDLLGRLAVSGAELLSATLDGIAEGALTARPQPADG
MSMEG_3064|M.smegmatis_MC2_155      YGVVTETVRDTDTAGDLLERLSDSGAELLERTIDGIADGSLTAVPQPSEG
TH_1529|M.thermoresistible__bu      YGVVTETIRPTDTAGDLLDRLADSGAELLERTLDGIEDGTLTAVPQPSEG
MAB_2811c|M.abscessus_ATCC_199      YGVVTERISPNDTAGALLGRLAESGAGLLESTMDGIEDGALVAVPQAVDG
                                    ****** :  .**** ** **: *** **. *:*** :  *..  *. :*

Mflv_3730|M.gilvum_PYR-GCK          VSIAPKVSVDDARIRWELPAHVVDRRIRSVTPNPGAWTMAGELRIKVGPV
Mvan_2687|M.vanbaalenii_PYR-1       VSVAPKVTVDDARIRWELPAHVVDRRVRSVTPNPGAWTMIGDQRIKVGPV
Mb1441|M.bovis_AF2122/97            VSVAPKITVANARVRWDLPAAVVERRIRAVTPNPGAWTLIGDLRVKLGPV
Rv1406|M.tuberculosis_H37Rv         VSVAPKITVANARVRWDLPAAVVERRIRAVTPNPGAWTLIGDLRVKLGPV
MLBr_00552|M.leprae_Br4923          VSFAPKITVEQARVCWDLPAPVVERRIRAVTPNPGAWTLVGKLRVKLGPV
MAV_3372|M.avium_104                VSIAPKITVEQARVRWDLPAPVVERRIRAVTPNPGAWTVIGDLRIKLGPV
MMAR_2215|M.marinum_M               VTLAPKISVEQARVRWELPAPIIERRIRAVTPNPGAWTLIGDLRVKLGPV
MUL_1802|M.ulcerans_Agy99           VTLAPKISVEQARVRWELPVPIIERRIRAVTPNPGAWTLIGDLRVKLGPV
MSMEG_3064|M.smegmatis_MC2_155      ITVAPKITVESARVRWDLPAHVVDRRIRAVTPNPGAWTMIGELRVKVGPV
TH_1529|M.thermoresistible__bu      VSYAPKITVEAARIRWDLPAHVVERRIRAMTPNPGAWTMIGDLRVKLGPV
MAB_2811c|M.abscessus_ATCC_199      VSIAPKITVEQARIRWELPAHAIDRHIRAMTPEPGAWTNIGGTRVKVGPV
                                    :: ***::*  **: *:**.  ::*::*::**:*****  *  *:*:***

Mflv_3730|M.gilvum_PYR-GCK          TVPD------DGPKDLEPGEIRVGKK-----HVHVGTATDAVLLGTVQPP
Mvan_2687|M.vanbaalenii_PYR-1       TVAG------DGPKGLEPGEIRVDKK-----HIHVGTGSDAVLLGTVQPP
Mb1441|M.bovis_AF2122/97            HLDA----AHRPSKPLPPGGIHVERT-----SVWIGTGSEPVRLGQIQPP
Rv1406|M.tuberculosis_H37Rv         HLDA----AHRPSKPLPPGGIHVERT-----SVWIGTGSEPVRLGQIQPP
MLBr_00552|M.leprae_Br4923          RFDSGAVEVPRLLKPLLPGGIHVDHK-----SVWIGTGSDPVRLSKVQPQ
MAV_3372|M.avium_104                RLGAAS-DLPAPPEPLPPGAIHVDRK-----SVWVGTASDPVRLDQIQPP
MMAR_2215|M.marinum_M               YLDA----AVKPPGPLPPGAIQVDRK-----HVWVGTGSEPLRLGQVQPP
MUL_1802|M.ulcerans_Agy99           YLDA----AVEPPGPLPPGAIQVDRK-----HVWVGTGSEPLRLGQVQPP
MSMEG_3064|M.smegmatis_MC2_155      TVDQ----AAEADGPLAPGEIRVGRN-----SVHVGTGSHPVRLGQIQPP
TH_1529|M.thermoresistible__bu      TVDD----DAE---PLAPGEIRAGRDGSGKQAVWFGTGTHPVRLGWIQPP
MAB_2811c|M.abscessus_ATCC_199      GVAT--------DEQLPPGAVAVRKR-----DVLVGTGTTAIALDEVQPQ
                                     .             * ** : . :       : .**.: .: *. :** 

Mflv_3730|M.gilvum_PYR-GCK          GKKSMNAADWARGARAEDIRRAR
Mvan_2687|M.vanbaalenii_PYR-1       GKKPMNAADWARGARLDENGWAR
Mb1441|M.bovis_AF2122/97            GKKLMNAADWARGARLDLAARAT
Rv1406|M.tuberculosis_H37Rv         GKKLMNAADWARGARLDLAARAT
MLBr_00552|M.leprae_Br4923          GKKFMNAVDWAHGARLDPAARAS
MAV_3372|M.avium_104                GKKFMNAVDWARGARLDPAARAT
MMAR_2215|M.marinum_M               GKKLMNAADWARGARLDPSVRAS
MUL_1802|M.ulcerans_Agy99           GKKLMNAADWARGARLDPSVRAS
MSMEG_3064|M.smegmatis_MC2_155      GKKLMNAADWARGARLEEPVSAS
TH_1529|M.thermoresistible__bu      GKKPMNAPDWARGARLDDTARAR
MAB_2811c|M.abscessus_ATCC_199      GKKVMKAADWARGARLDAEVHAL
                                    *** *:* ***:*** :    *