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MRVVFFGYQTWGYRTLQALIDLGHEIVLAVTHPMSEDAYKAIWAAPVEELAREHGIPAHFTKRVDAETID LVRSVDPDVIVVNSWYNRMPVELYDLPPYGTLNFHDSLLPKFTGFSPVLWALISGESEFGLTVHRMDSGL DTGDILVQRSLPIGPTDTGTELVLRGMELIPRVLAEALNALESGSAAWRPQNKAERTFCHKRSEQDSALD WAWPAEDLERFVRALSEPYPRAFAFYNTERIEVLEARVSEARYGGTPGRVTVQEQGGAVVCGPGAHRAAN RGLVITRIRRADGSEVSGEEYFRRGGYLDGGN
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2260 | - | - | 100% (312) | putative formyltransferase |
| M. abscessus ATCC 19977 | MAB_2811c | - | 2e-20 | 27.44% (277) | methionyl-tRNA formyltransferase |
| M. abscessus ATCC 19977 | MAB_1063 | purN | 9e-09 | 25.83% (151) | phosphoribosylglycinamide formyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1441 | fmt | 2e-17 | 26.54% (260) | methionyl-tRNA formyltransferase |
| M. gilvum PYR-GCK | Mflv_3730 | fmt | 3e-21 | 29.67% (246) | methionyl-tRNA formyltransferase |
| M. tuberculosis H37Rv | Rv1406 | fmt | 2e-17 | 26.54% (260) | methionyl-tRNA formyltransferase |
| M. leprae Br4923 | MLBr_00552 | fmt | 1e-15 | 26.42% (246) | methionyl-tRNA formyltransferase |
| M. marinum M | MMAR_2215 | fmt | 1e-18 | 28.05% (246) | methionyl-tRNA formyltransferase Fmt |
| M. avium 104 | MAV_3372 | fmt | 4e-20 | 28.74% (254) | methionyl-tRNA formyltransferase |
| M. smegmatis MC2 155 | MSMEG_0014 | - | 1e-97 | 55.05% (307) | Formyl transferase |
| M. thermoresistible (build 8) | TH_1529 | fmt | 7e-24 | 29.79% (282) | PROBABLE METHIONYL-TRNA FORMYLTRANSFERASE FMT |
| M. ulcerans Agy99 | MUL_1802 | fmt | 4e-19 | 28.05% (246) | methionyl-tRNA formyltransferase |
| M. vanbaalenii PYR-1 | Mvan_2687 | fmt | 3e-21 | 28.25% (269) | methionyl-tRNA formyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1441|M.bovis_AF2122/97 ---MRLVFAGTPEPALASLRRLIESPSHDVIAVLTRPDAASGRRGKPQPS
Rv1406|M.tuberculosis_H37Rv ---MRLVFAGTPEPALASLRRLIESPSHDVIAVLTRPDAASGRRGKPQPS
MLBr_00552|M.leprae_Br4923 -MLVRLVFAGTPESALPALCRLIDSPRHDVIAVLTRPDAASGRRGKPEPS
MAV_3372|M.avium_104 -MPVRLVFAGTPEPALPALRRLLDSPRHEVIAVLTRPDAASGRRGKPEPS
MMAR_2215|M.marinum_M ---MRLVFAGTPETALPALHQLIDSPRHDVIAVLTRPDAASGRRGKPEPS
MUL_1802|M.ulcerans_Agy99 ---MRLVFAGTPETALPALHQLIDSPRHDVIAVLTRPDAASGRRGKPEPS
Mflv_3730|M.gilvum_PYR-GCK ---MRLVFAGTPEPALPSLQRLIDSARHDVIAVLTRPDAAAGRRGRPSPS
Mvan_2687|M.vanbaalenii_PYR-1 ---MRLVFAGTPEPALPSLQRLIDSDRHEVIAVMTRPDAVAGRRGRPSPS
TH_1529|M.thermoresistible__bu ---MRLVFAGTPEAALPSLRRLIDXXRHEVVAVLTRPDAAAGRRARPAPS
MAB_2260|M.abscessus_ATCC_1997 ---MRVVFFGYQTWGYRTLQALIDLG-HEIVLAVTHPMSEDAYKA-IWAA
MSMEG_0014|M.smegmatis_MC2_155 MFPVRVVMFGYQTWGHRTLQALLKSR-HEVCLVVTHPTSDHAYES-IWAD
:*:*: * . :* *:. *:: .:*:* : . .. .
Mb1441|M.bovis_AF2122/97 PVAREAAERGIPVLRPSRPNSAEFVAELSDLAPECCAVVAYGALLGGPLL
Rv1406|M.tuberculosis_H37Rv PVAREAAERGIPVLRPSRPNSAEFVAELSDLAPECCAVVAYGALLGGPLL
MLBr_00552|M.leprae_Br4923 PVAREALDRGIPLLRPARPNSPVFVSELSEWAPECCVVVAYGALLGSPLL
MAV_3372|M.avium_104 PVAREALDRGIPVLRPARPNSPEFVAELAQLAPDCCAVVAYGALLRDELL
MMAR_2215|M.marinum_M PVARAALERDIPVLRPSRPNSAEFVAELSELAPQCCAVVAYGALLGDALL
MUL_1802|M.ulcerans_Agy99 PVARAALERGIPVLRPSRPNSAEFVAELSELAPQCCAVVAYGALLGDALL
Mflv_3730|M.gilvum_PYR-GCK PVAELAAAHGIPVLKPPRPNSEEFVAELAALAPDCCAVVAYGALLREELL
Mvan_2687|M.vanbaalenii_PYR-1 PVAQLAAAHGIPVLKPARPNSGEFVAELSALSPDCCAVVAYGALLGDALL
TH_1529|M.thermoresistible__bu PVAKLASEHGIPVLRPPSPNTDEFIAELTELAPDCCPVVAYGALLSERLL
MAB_2260|M.abscessus_ATCC_1997 PVEELAREHGIPAHFTKRVD-AETIDLVRSVDPDVIVVNSWYNRMPVELY
MSMEG_0014|M.smegmatis_MC2_155 SVEDLARGAGIEVLLAKRPT-PELVERVRELAPDVGVANNWRTRLPRELF
.* * .* . : : *: . : : *
Mb1441|M.bovis_AF2122/97 AVPPHGWVNLHFSLLPAWRGAAPVQAAIAAGDTITGATTFQIEPSLDSGP
Rv1406|M.tuberculosis_H37Rv AVPPHGWVNLHFSLLPAWRGAAPVQAAIAAGDTITGATTFQIEPSLDSGP
MLBr_00552|M.leprae_Br4923 AVPPRGWVNLHFSLLPAWRGAAPVQAAIAAGDTITGATTFQIEPSLDSGP
MAV_3372|M.avium_104 AVPPHGWINLHFSLLPAWRGAAPVQAAIAAGDTITGATTFRIEPALDSGP
MMAR_2215|M.marinum_M GVPPQGWVNLHFSLLPAWRGAAPVQAAIAAGDAVTGATTFQIEPSLDSGP
MUL_1802|M.ulcerans_Agy99 GVPPQGWVNLHFSLLPAWRGAAPVQAAIAAGDAVTGATTFQIEPSLDSGP
Mflv_3730|M.gilvum_PYR-GCK AVPALGWVNLHFSVLPAWRGAAPVQAALAAGDEVTGATTFQIELSLDSGP
Mvan_2687|M.vanbaalenii_PYR-1 AVPAHGWVNLHFSVLPAWRGAAPVQAALAAGDEVTGATTFQIERSLDSGP
TH_1529|M.thermoresistible__bu AVPRHGWVNLHFSLLPAWRGAAPVQAAIAAGDTVTGASTFRIEPALDSGP
MAB_2260|M.abscessus_ATCC_1997 DLPPYGTLNFHDSLLPKFTGFSPVLWALISGESEFGLTVHRMDSGLDTGD
MSMEG_0014|M.smegmatis_MC2_155 SIPKYGTVNLHDSLLPKFTGFSPVIWSLISGAGQTGLTAHFMDDELDTGD
:* * :*:* *:** : * :** :: :* * :.. :: **:*
Mb1441|M.bovis_AF2122/97 IYGVVTEVIQPTDTAGDLLKRLAVSGAALLSTTLDGIADQRLTPRPQPAD
Rv1406|M.tuberculosis_H37Rv IYGVVTEVIQPTDTAGDLLKRLAVSGAALLSTTLDGIADQRLTPRPQPAD
MLBr_00552|M.leprae_Br4923 VYGVVTETIQPTDTAGDLLERLAVSGATLLSSTLDGIADAILTPRQQPVD
MAV_3372|M.avium_104 IYGVVTEAIRPTDTAGELLARLAVSGAELLSATLDGIADSTLTPRPQPAE
MMAR_2215|M.marinum_M VYGVVTETIRPTDTAGDLLGRLAVSGAELLSATLDGIAEGALTARPQPAD
MUL_1802|M.ulcerans_Agy99 VYGVVTETIRPTDTAGDLLGRLAVSGAELLSATLDGIAEGALTARPQPAD
Mflv_3730|M.gilvum_PYR-GCK VYGVVTETIRPTDTAGDLLGRLAESGAGLLEATMDGIEDGTLTAVPQPAE
Mvan_2687|M.vanbaalenii_PYR-1 VYGVVTETIRPTDTAGDLLERLSVSGAGLLEATMDGIEDGTLTAVPQPPE
TH_1529|M.thermoresistible__bu IYGVVTETIRPTDTAGDLLDRLADSGAELLERTLDGIEDGTLTAVPQPSE
MAB_2260|M.abscessus_ATCC_1997 ILVQRSLPIGPTDTGTELVLRGMELIPRVLAEALNALESGSAAWRPQNKA
MSMEG_0014|M.smegmatis_MC2_155 ILLQRSVEITPTSTGTSLVYDTLDLIPDVLEDALDAIENGTATPVPQDLS
: : * **.*. .*: . :* :::.: . : *
Mb1441|M.bovis_AF2122/97 GVSVAPKITVANARVRWDLPAAVVERRIRAVT-PNPGAWTLIGDLRVKLG
Rv1406|M.tuberculosis_H37Rv GVSVAPKITVANARVRWDLPAAVVERRIRAVT-PNPGAWTLIGDLRVKLG
MLBr_00552|M.leprae_Br4923 GVSFAPKITVEQARVCWDLPAPVVERRIRAVT-PNPGAWTLVGKLRVKLG
MAV_3372|M.avium_104 GVSIAPKITVEQARVRWDLPAPVVERRIRAVT-PNPGAWTVIGDLRIKLG
MMAR_2215|M.marinum_M GVTLAPKISVEQARVRWELPAPIIERRIRAVT-PNPGAWTLIGDLRVKLG
MUL_1802|M.ulcerans_Agy99 GVTLAPKISVEQARVRWELPVPIIERRIRAVT-PNPGAWTLIGDLRVKLG
Mflv_3730|M.gilvum_PYR-GCK GVSIAPKVSVDDARIRWELPAHVVDRRIRSVT-PNPGAWTMAGELRIKVG
Mvan_2687|M.vanbaalenii_PYR-1 GVSVAPKVTVDDARIRWELPAHVVDRRVRSVT-PNPGAWTMIGDQRIKVG
TH_1529|M.thermoresistible__bu GVSYAPKITVEAARIRWDLPAHVVERRIRAMT-PNPGAWTMIGDLRVKLG
MAB_2260|M.abscessus_ATCC_1997 ERTFCHKRSEQDSALDWAWPAEDLERFVRALSEPYPRAFAFYNTERIEVL
MSMEG_0014|M.smegmatis_MC2_155 QRTFFHKRSDRDSLVDWSWPAADIERFIRALSDPYPNAYTYFRGERLRLI
: * : : : * *. ::* :*::: * * *:: *:.:
Mb1441|M.bovis_AF2122/97 PVHLDA----AHRPSKPLPPGGIHVER-----TSVWIGTGSEP-----VR
Rv1406|M.tuberculosis_H37Rv PVHLDA----AHRPSKPLPPGGIHVER-----TSVWIGTGSEP-----VR
MLBr_00552|M.leprae_Br4923 PVRFDSGAVEVPRLLKPLLPGGIHVDH-----KSVWIGTGSDP-----VR
MAV_3372|M.avium_104 PVRLGAAS-DLPAPPEPLPPGAIHVDR-----KSVWVGTASDP-----VR
MMAR_2215|M.marinum_M PVYLDA----AVKPPGPLPPGAIQVDR-----KHVWVGTGSEP-----LR
MUL_1802|M.ulcerans_Agy99 PVYLDA----AVEPPGPLPPGAIQVDR-----KHVWVGTGSEP-----LR
Mflv_3730|M.gilvum_PYR-GCK PVTVPD------DGPKDLEPGEIRVGK-----KHVHVGTATDA-----VL
Mvan_2687|M.vanbaalenii_PYR-1 PVTVAG------DGPKGLEPGEIRVDK-----KHIHVGTGSDA-----VL
TH_1529|M.thermoresistible__bu PVTVDD-------DAEPLAPGEIRAGRDGSGKQAVWFGTGTHP-----VR
MAB_2260|M.abscessus_ATCC_1997 EARVSE-------ARYGGTPGRVTVQE--QGG-AVVCGPGAHRAANRGLV
MSMEG_0014|M.smegmatis_MC2_155 SAHVSR-------CTYGGTPGRVFIEE--NGGMVIVAGADAFRGRSPGLV
. . ** : . : *. : :
Mb1441|M.bovis_AF2122/97 LGQIQPPGKKLMNAADWARGARLDLAARAT----
Rv1406|M.tuberculosis_H37Rv LGQIQPPGKKLMNAADWARGARLDLAARAT----
MLBr_00552|M.leprae_Br4923 LSKVQPQGKKFMNAVDWAHGARLDPAARAS----
MAV_3372|M.avium_104 LDQIQPPGKKFMNAVDWARGARLDPAARAT----
MMAR_2215|M.marinum_M LGQVQPPGKKLMNAADWARGARLDPSVRAS----
MUL_1802|M.ulcerans_Agy99 LGQVQPPGKKLMNAADWARGARLDPSVRAS----
Mflv_3730|M.gilvum_PYR-GCK LGTVQPPGKKSMNAADWARGARAEDIRRAR----
Mvan_2687|M.vanbaalenii_PYR-1 LGTVQPPGKKPMNAADWARGARLDENGWAR----
TH_1529|M.thermoresistible__bu LGWIQPPGKKPMNAPDWARGARLDDTARAR----
MAB_2260|M.abscessus_ATCC_1997 ITRIRRADGSEVSGEEYFRRGG-YLDGGN-----
MSMEG_0014|M.smegmatis_MC2_155 LDVVRTDDGIDHSALDYFGHGGGYLTATPEFATV
: :: . .. :: .