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MTEQQWNFAGIEAASSAIQGNVTSIHSLLDEGKQSLHKLAAAWGGSGSEAYRGVQQNWDSTAQELNNSLQ NLARTISEAGQAMSSTEGNVTGMFA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_5450 | esxA | - | 100% (95) | 6 kDa early secretory antigenic target EsxA (EsaT-6) |
| M. marinum M | MMAR_0188 | esxA_1 | 7e-46 | 92.55% (94) | 6 kDa culture filtrate antigen EsxA_1 (early secreted |
| M. marinum M | MMAR_0189 | esxA_3 | 2e-16 | 42.11% (95) | EsxA-like protein, EsxA_3 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3905 | esxA | 3e-46 | 91.58% (95) | 6 kDa early secretory antigenic target EsaT6 (EsaT-6) |
| M. gilvum PYR-GCK | Mflv_0766 | - | 2e-18 | 46.67% (90) | early secretory antigenic target, 6 kDa |
| M. tuberculosis H37Rv | Rv3875 | esxA | 3e-46 | 91.58% (95) | 6 kDa early secretory antigenic target ESXA (ESAT-6) |
| M. leprae Br4923 | MLBr_00049 | - | 1e-16 | 36.26% (91) | putative secreted protein |
| M. abscessus ATCC 19977 | MAB_2326c | - | 2e-10 | 33.33% (90) | hypothetical protein MAB_2326c |
| M. avium 104 | MAV_4642 | - | 1e-05 | 24.68% (77) | hypothetical protein MAV_4642 |
| M. smegmatis MC2 155 | MSMEG_0066 | - | 6e-32 | 67.37% (95) | early secretory antigenic target, 6 kDa |
| M. thermoresistible (build 8) | TH_2268 | esat6 | 9e-29 | 62.11% (95) | 6 KDA EARLY SECRETORY ANTIGENIC TARGET ESXA (ESAT-6) |
| M. ulcerans Agy99 | MUL_2243 | esxR | 4e-05 | 25.29% (87) | EsaT-6 family protein |
| M. vanbaalenii PYR-1 | Mvan_0079 | - | 4e-15 | 40.45% (89) | 6 kDa early secretory antigenic target EsaT6 (EsaT-6) |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3905|M.bovis_AF2122/97 --MTEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGS
Rv3875|M.tuberculosis_H37Rv --MTEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGS
MMAR_5450|M.marinum_M --MTEQQWNFAGIEAASSAIQGNVTSIHSLLDEGKQSLHKLAAAWGGSGS
MSMEG_0066|M.smegmatis_MC2_155 --MTEQVWNFAGIEGGASEIHGAVSTTAGLLDEGKASLTTLASAWGGTGS
TH_2268|M.thermoresistible__bu --MSQQVWNFAGIEGGAGEIHAAVGTTAGLLDEGKASLAALASAWGGSGS
Mflv_0766|M.gilvum_PYR-GCK ---MALAYNFAGIDNNAGEIMGAVGRTEGLLQEGQGSLARLSAVWGGTAS
Mvan_0079|M.vanbaalenii_PYR-1 ----MITYNFAGIESDAGEISGQVGKVAGLLAEGHGALTRLQAVWTGDGQ
MLBr_00049|M.leprae_Br4923 ---MIQAWHFPALQGAVNELQGSQSRIDALLEQCQESLTKLQSSWHGSGN
MAB_2326c|M.abscessus_ATCC_199 --MADLVYDYAKISALVGDWQASIARLQQLLDEQRAEVNKLAESWTGATG
MUL_2243|M.ulcerans_Agy99 --MSQIMYNYPAMLAHAGDMSGYAGSLHGLGADIAAEQAALSNAWQGDTG
MAV_4642|M.avium_104 MSDNTVRVDPVVMQGAAASLSGAAEHLSAQLGQLDDQVGQMLGGWQGASG
. : . : : * *
Mb3905|M.bovis_AF2122/97 EAYQGVQQKWDATATELNNALQNLARTISEAGQAMASTEGNVTG---MFA
Rv3875|M.tuberculosis_H37Rv EAYQGVQQKWDATATELNNALQNLARTISEAGQAMASTEGNVTG---MFA
MMAR_5450|M.marinum_M EAYRGVQQNWDSTAQELNNSLQNLARTISEAGQAMSSTEGNVTG---MFA
MSMEG_0066|M.smegmatis_MC2_155 EAYQAVQARWDSTSNELNLALQNLAQTISEAGQTMAQTEAGVTG---MFA
TH_2268|M.thermoresistible__bu EAYQAVQMRWDSVSAELNAALQNLAQTISEAGANMAQTEAGVTG---MFA
Mflv_0766|M.gilvum_PYR-GCK DAYVAVQNRWDSSSNELNMALKSLANAIAQAGHDMGATEMRNQG---KFA
Mvan_0079|M.vanbaalenii_PYR-1 MAYDAVQNRWNQNSEELNLALQSLSEALSRSGGDMFGADQGVAG---QFT
MLBr_00049|M.leprae_Br4923 ESYSSVQQRFNQNTEGINHALGDLVQAINHSAETMQQTEAGVTS---MFT
MAB_2326c|M.abscessus_ATCC_199 DAFRREQKIWQQTADTLLAAAKKLGGLISAAAEAMAKTEAGVANNP-QFS
MUL_2243|M.ulcerans_Agy99 VTYQGWQTQWNQAMEDLVRAYQSMASTHESNTLAMSARDQAEAA---KWG
MAV_4642|M.avium_104 SAYAAAWELWHRGAREVQLGLAMLARLVGQAGEAYASNEAGAAQAERAVR
:: :. : . : :
Mb3905|M.bovis_AF2122/97 ---
Rv3875|M.tuberculosis_H37Rv ---
MMAR_5450|M.marinum_M ---
MSMEG_0066|M.smegmatis_MC2_155 ---
TH_2268|M.thermoresistible__bu ---
Mflv_0766|M.gilvum_PYR-GCK ---
Mvan_0079|M.vanbaalenii_PYR-1 ---
MLBr_00049|M.leprae_Br4923 G--
MAB_2326c|M.abscessus_ATCC_199 GSD
MUL_2243|M.ulcerans_Agy99 A--
MAV_4642|M.avium_104 GG-