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MAVLHYNFAAIEIGVAEIQAEVIKTQKHLHDANQVLSTLTEVWGGSGSEAYQQVQQQWDSASADLNAALQ ALAHAIHQSNQEMLTTETGLATLFS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_0189 | esxA_3 | - | 100% (95) | EsxA-like protein, EsxA_3 |
| M. marinum M | MMAR_0196 | esxA_2 | 6e-49 | 97.89% (95) | EsxA-like protein, EsxA_2 |
| M. marinum M | MMAR_0188 | esxA_1 | 1e-16 | 44.68% (94) | 6 kDa culture filtrate antigen EsxA_1 (early secreted |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3905 | esxA | 9e-18 | 43.16% (95) | 6 kDa early secretory antigenic target EsaT6 (EsaT-6) |
| M. gilvum PYR-GCK | Mflv_0766 | - | 2e-15 | 45.24% (84) | early secretory antigenic target, 6 kDa |
| M. tuberculosis H37Rv | Rv3875 | esxA | 9e-18 | 43.16% (95) | 6 kDa early secretory antigenic target ESXA (ESAT-6) |
| M. leprae Br4923 | MLBr_00049 | - | 9e-11 | 32.22% (90) | putative secreted protein |
| M. abscessus ATCC 19977 | MAB_2326c | - | 4e-08 | 30.77% (91) | hypothetical protein MAB_2326c |
| M. avium 104 | MAV_4387 | - | 8e-05 | 25.81% (93) | hypothetical protein MAV_4387 |
| M. smegmatis MC2 155 | MSMEG_0066 | - | 2e-18 | 47.78% (90) | early secretory antigenic target, 6 kDa |
| M. thermoresistible (build 8) | TH_2268 | esat6 | 3e-19 | 50.00% (90) | 6 KDA EARLY SECRETORY ANTIGENIC TARGET ESXA (ESAT-6) |
| M. ulcerans Agy99 | MUL_0863 | esxT | 8e-06 | 31.71% (82) | EsaT-6 like protein, EsxT |
| M. vanbaalenii PYR-1 | Mvan_0079 | - | 1e-13 | 38.71% (93) | 6 kDa early secretory antigenic target EsaT6 (EsaT-6) |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3905|M.bovis_AF2122/97 -MTEQQWNFAGIEAAAS-AIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGS
Rv3875|M.tuberculosis_H37Rv -MTEQQWNFAGIEAAAS-AIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGS
MSMEG_0066|M.smegmatis_MC2_155 -MTEQVWNFAGIEGGAS-EIHGAVSTTAGLLDEGKASLTTLASAWGGTGS
TH_2268|M.thermoresistible__bu -MSQQVWNFAGIEGGAG-EIHAAVGTTAGLLDEGKASLAALASAWGGSGS
Mflv_0766|M.gilvum_PYR-GCK --MALAYNFAGIDNNAG-EIMGAVGRTEGLLQEGQGSLARLSAVWGGTAS
Mvan_0079|M.vanbaalenii_PYR-1 ---MITYNFAGIESDAG-EISGQVGKVAGLLAEGHGALTRLQAVWTGDGQ
MMAR_0189|M.marinum_M -MAVLHYNFAAIEIGVA-EIQAEVIKTQKHLHDANQVLSTLTEVWGGSGS
MLBr_00049|M.leprae_Br4923 --MIQAWHFPALQGAVN-ELQGSQSRIDALLEQCQESLTKLQSSWHGSGN
MAB_2326c|M.abscessus_ATCC_199 -MADLVYDYAKISALVG-DWQASIARLQQLLDEQRAEVNKLAESWTGATG
MAV_4387|M.avium_104 MDPTLSYNFGEIEHSVRQEIHTTSARFNAALDELRARIAPLQQLWTSEAA
MUL_0863|M.ulcerans_Agy99 MDPVRSYNFDAIEHTVRQEIHITSMRFNAALEQLRSQIAPLQQLWSREAA
:.: :. . * : . : * *
Mb3905|M.bovis_AF2122/97 EAYQGVQQKWDATATELNNALQNLARTISEAGQAMASTEGNVTG--MFA-
Rv3875|M.tuberculosis_H37Rv EAYQGVQQKWDATATELNNALQNLARTISEAGQAMASTEGNVTG--MFA-
MSMEG_0066|M.smegmatis_MC2_155 EAYQAVQARWDSTSNELNLALQNLAQTISEAGQTMAQTEAGVTG--MFA-
TH_2268|M.thermoresistible__bu EAYQAVQMRWDSVSAELNAALQNLAQTISEAGANMAQTEAGVTG--MFA-
Mflv_0766|M.gilvum_PYR-GCK DAYVAVQNRWDSSSNELNMALKSLANAIAQAGHDMGATEMRNQG--KFA-
Mvan_0079|M.vanbaalenii_PYR-1 MAYDAVQNRWNQNSEELNLALQSLSEALSRSGGDMFGADQGVAG--QFT-
MMAR_0189|M.marinum_M EAYQQVQQQWDSASADLNAALQALAHAIHQSNQEMLTTETGLAT--LFS-
MLBr_00049|M.leprae_Br4923 ESYSSVQQRFNQNTEGINHALGDLVQAINHSAETMQQTEAGVTS--MFTG
MAB_2326c|M.abscessus_ATCC_199 DAFRREQKIWQQTADTLLAAAKKLGGLISAAAEAMAKTEAGVANNPQFSG
MAV_4387|M.avium_104 TAYQAEQLKWHRSATALNEILVQLGDAVRDGAEEVADADRRAAG--VWAR
MUL_0863|M.ulcerans_Agy99 AAYQTEQFKWHQAAATLNQILVELGNAVRDGADEVAGADRRAAG--GWAR
:: * :. : : * : . : :: ::
Mb3905|M.bovis_AF2122/97 --
Rv3875|M.tuberculosis_H37Rv --
MSMEG_0066|M.smegmatis_MC2_155 --
TH_2268|M.thermoresistible__bu --
Mflv_0766|M.gilvum_PYR-GCK --
Mvan_0079|M.vanbaalenii_PYR-1 --
MMAR_0189|M.marinum_M --
MLBr_00049|M.leprae_Br4923 --
MAB_2326c|M.abscessus_ATCC_199 SD
MAV_4387|M.avium_104 --
MUL_0863|M.ulcerans_Agy99 --