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M. bovis AF2122 / 97 Mb3905 (esxA)

annotation: 6 kDa early secretory antigenic target EsaT6 (EsaT-6)
coordinates: 4288929 - 4289216
length: 95

MTEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDATATELNNALQ
NLARTISEAGQAMASTEGNVTGMFA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3905esxA-100% (95)6 kDa early secretory antigenic target EsaT6 (EsaT-6)
M. bovis AF2122 / 97Mb3045cesxR2e-0526.14% (88) putative secreted ESAT-6 like protein 9 TB10.3

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_0766-3e-1947.78% (90) early secretory antigenic target, 6 kDa
M. tuberculosis H37RvRv3875esxA4e-50100.00% (95) 6 kDa early secretory antigenic target ESXA (ESAT-6)
M. leprae Br4923MLBr_00049-1e-1738.46% (91) putative secreted protein
M. abscessus ATCC 19977MAB_2326c-1e-1034.44% (90) hypothetical protein MAB_2326c
M. marinum MMMAR_5450esxA5e-4691.58% (95) 6 kDa early secretory antigenic target EsxA (EsaT-6)
M. avium 104MAV_4387-1e-0627.47% (91) hypothetical protein MAV_4387
M. smegmatis MC2 155MSMEG_0066-4e-3471.58% (95) early secretory antigenic target, 6 kDa
M. thermoresistible (build 8)TH_2268esat62e-3065.26% (95) 6 KDA EARLY SECRETORY ANTIGENIC TARGET ESXA (ESAT-6)
M. ulcerans Agy99MUL_2243esxR8e-0627.59% (87) EsaT-6 family protein
M. vanbaalenii PYR-1Mvan_0079-1e-1643.82% (89) 6 kDa early secretory antigenic target EsaT6 (EsaT-6)

CLUSTAL 2.0.9 multiple sequence alignment


Mb3905|M.bovis_AF2122/97            -MTEQQWNFAGIEAAAS-AIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGS
Rv3875|M.tuberculosis_H37Rv         -MTEQQWNFAGIEAAAS-AIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGS
MMAR_5450|M.marinum_M               -MTEQQWNFAGIEAASS-AIQGNVTSIHSLLDEGKQSLHKLAAAWGGSGS
MSMEG_0066|M.smegmatis_MC2_155      -MTEQVWNFAGIEGGAS-EIHGAVSTTAGLLDEGKASLTTLASAWGGTGS
TH_2268|M.thermoresistible__bu      -MSQQVWNFAGIEGGAG-EIHAAVGTTAGLLDEGKASLAALASAWGGSGS
MLBr_00049|M.leprae_Br4923          --MIQAWHFPALQGAVN-ELQGSQSRIDALLEQCQESLTKLQSSWHGSGN
Mflv_0766|M.gilvum_PYR-GCK          --MALAYNFAGIDNNAG-EIMGAVGRTEGLLQEGQGSLARLSAVWGGTAS
Mvan_0079|M.vanbaalenii_PYR-1       ---MITYNFAGIESDAG-EISGQVGKVAGLLAEGHGALTRLQAVWTGDGQ
MAB_2326c|M.abscessus_ATCC_199      -MADLVYDYAKISALVG-DWQASIARLQQLLDEQRAEVNKLAESWTGATG
MUL_2243|M.ulcerans_Agy99           -MSQIMYNYPAMLAHAG-DMSGYAGSLHGLGADIAAEQAALSNAWQGDTG
MAV_4387|M.avium_104                MDPTLSYNFGEIEHSVRQEIHTTSARFNAALDELRARIAPLQQLWTSEAA
                                          :.:  :                    :       *   * .   

Mb3905|M.bovis_AF2122/97            EAYQGVQQKWDATATELNNALQNLARTISEAGQAMASTEGNVTG--MFA-
Rv3875|M.tuberculosis_H37Rv         EAYQGVQQKWDATATELNNALQNLARTISEAGQAMASTEGNVTG--MFA-
MMAR_5450|M.marinum_M               EAYRGVQQNWDSTAQELNNSLQNLARTISEAGQAMSSTEGNVTG--MFA-
MSMEG_0066|M.smegmatis_MC2_155      EAYQAVQARWDSTSNELNLALQNLAQTISEAGQTMAQTEAGVTG--MFA-
TH_2268|M.thermoresistible__bu      EAYQAVQMRWDSVSAELNAALQNLAQTISEAGANMAQTEAGVTG--MFA-
MLBr_00049|M.leprae_Br4923          ESYSSVQQRFNQNTEGINHALGDLVQAINHSAETMQQTEAGVTS--MFTG
Mflv_0766|M.gilvum_PYR-GCK          DAYVAVQNRWDSSSNELNMALKSLANAIAQAGHDMGATEMRNQG--KFA-
Mvan_0079|M.vanbaalenii_PYR-1       MAYDAVQNRWNQNSEELNLALQSLSEALSRSGGDMFGADQGVAG--QFT-
MAB_2326c|M.abscessus_ATCC_199      DAFRREQKIWQQTADTLLAAAKKLGGLISAAAEAMAKTEAGVANNPQFSG
MUL_2243|M.ulcerans_Agy99           VTYQGWQTQWNQAMEDLVRAYQSMASTHESNTLAMSARDQAEAA--KWGA
MAV_4387|M.avium_104                TAYQAEQLKWHRSATALNEILVQLGDAVRDGAEEVADADRRAAG--VWAR
                                     ::   *  :.     :     .:          :   :        :  

Mb3905|M.bovis_AF2122/97            --
Rv3875|M.tuberculosis_H37Rv         --
MMAR_5450|M.marinum_M               --
MSMEG_0066|M.smegmatis_MC2_155      --
TH_2268|M.thermoresistible__bu      --
MLBr_00049|M.leprae_Br4923          --
Mflv_0766|M.gilvum_PYR-GCK          --
Mvan_0079|M.vanbaalenii_PYR-1       --
MAB_2326c|M.abscessus_ATCC_199      SD
MUL_2243|M.ulcerans_Agy99           --
MAV_4387|M.avium_104                --