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MTQPKLHGMHQACDHSGASIVAAVSSRRSALTAAGLAVVGAGVLATSACGPGESPAPPSPAALPENALIT LGVAAGPPPTPNKIGISSVLKIGGDLYLIDCGLGSLNAFTNAGLQFNDLKAIFITHLHTDHIVDYYSFFL SGGFQAPPGRAPIPVYGPGPAGGLPPSEIGNKNPATVNPANPTPGLAATTEALHQAFAYSSNIFIRDYGI DNVQDLAKVIEIPVPAGSDYRNTAPKVSPFPVVSDDNVSVTTTLVPHYDVYPAFAFRFDVKDPAVSITFS GDTTKSDNLVALANGTDILVHEAMFSLDTAYYGNVFPPDYLPKSHTSAEQVGEVAAVVKPKHLILSHYAP DDLPDSQWLDKINQNYSGRTTVAKDGQIFAL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_5358 | - | - | 100% (381) | hypothetical protein MMAR_5358 |
| M. marinum M | MMAR_3727 | - | 4e-18 | 26.28% (312) | metal-dependent hydrolase |
| M. marinum M | MMAR_4043 | - | 2e-06 | 30.30% (99) | metal-dependent hydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3825 | - | 1e-176 | 80.05% (376) | hypothetical protein Mb3825 |
| M. gilvum PYR-GCK | Mflv_2669 | - | 4e-18 | 26.78% (295) | ribonuclease Z |
| M. tuberculosis H37Rv | Rv3796 | - | 1e-177 | 80.32% (376) | hypothetical protein Rv3796 |
| M. leprae Br4923 | MLBr_01173 | - | 1e-08 | 30.61% (98) | hypothetical protein MLBr_01173 |
| M. abscessus ATCC 19977 | MAB_1483 | - | 6e-07 | 23.46% (260) | hypothetical protein MAB_1483 |
| M. avium 104 | MAV_1774 | - | 3e-20 | 25.81% (310) | ribonuclease Z |
| M. smegmatis MC2 155 | MSMEG_4568 | - | 2e-19 | 26.75% (314) | ribonuclease Z |
| M. thermoresistible (build 8) | TH_1457 | - | 2e-15 | 23.55% (310) | CONSERVED HYPOTHETCAL PROTEIN |
| M. ulcerans Agy99 | MUL_3670 | - | 7e-18 | 26.28% (312) | ribonuclease Z |
| M. vanbaalenii PYR-1 | Mvan_3908 | - | 5e-18 | 26.25% (301) | ribonuclease Z |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3825|M.bovis_AF2122/97 ----MLLGMHQAG-HVGTHERRAAATRRSALTAAGLAVVGAGVLGASACS
Rv3796|M.tuberculosis_H37Rv ----MLLGMHQAG-HVGTHERRAAATRRSALTAAGLAVVGAGVLGASACS
MMAR_5358|M.marinum_M MTQPKLHGMHQACDHSGASIVAAVSSRRSALTAAGLAVVGAGVLATSACG
Mflv_2669|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3908|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4568|M.smegmatis_MC2_155 --------------------------------------------------
MAV_1774|M.avium_104 --------------------------------------------------
MUL_3670|M.ulcerans_Agy99 --------------------------------------------------
TH_1457|M.thermoresistible__bu --------------------------------------------------
MLBr_01173|M.leprae_Br4923 --------------------------------------------------
MAB_1483|M.abscessus_ATCC_1997 --------------------------------------------------
Mb3825|M.bovis_AF2122/97 PQKSPQPSSPR-LPDNALITLGVAAGPPPTPSRVGISSVLKIG-RDLYVI
Rv3796|M.tuberculosis_H37Rv PQKSPQPSSPR-LPDNALITLGVAAGPPPTPSRVGISSVLKIG-RDLYVI
MMAR_5358|M.marinum_M PGESPAPPSPAALPENALITLGVAAGPPPTPNKIGISSVLKIG-GDLYLI
Mflv_2669|M.gilvum_PYR-GCK ---------------MIEVTLLGTGSPIPDARRAGPSTLVRAG-GQTFLV
Mvan_3908|M.vanbaalenii_PYR-1 -MSPVGRPPRVTSGLMIEVTLLGTGSPIPDARRAGPSTLVRAG-GQTFLV
MSMEG_4568|M.smegmatis_MC2_155 ---------------MIEVTLLGTGSPIPDPDRAGPSTMVRAG-GQTFLV
MAV_1774|M.avium_104 ---------------MIEVTLLGTGSPIPDPNRAGPSTLVRAG-GQVFLV
MUL_3670|M.ulcerans_Agy99 ---------------MIEITLLGTGSPIPDPDRAGPSTLVRAG-GQVFLV
TH_1457|M.thermoresistible__bu ---------------MIEVTLLGTGSPVPDAHRAGPSTLVRAG-HQTLLI
MLBr_01173|M.leprae_Br4923 --------------MTVRITVLGCSGSVVGPDSPASGYLLRAPDTPPLVL
MAB_1483|M.abscessus_ATCC_1997 ----------------MRVTVLGCSGSVTGPDSPASGYLLTAPDAPPLVI
:*: ... . . . :: ::
Mb3825|M.bovis_AF2122/97 DCGLGSLNAFTNAGLQFDDLKAMFITHLHTDHIVDYYNFFLSGGFLAP-P
Rv3796|M.tuberculosis_H37Rv DCGLGSLNAFTNAGLQFDDLKAMFITHLHTDHIVDYYNFFLSGGFLAP-P
MMAR_5358|M.marinum_M DCGLGSLNAFTNAGLQFNDLKAIFITHLHTDHIVDYYSFFLSGGFQAP-P
Mflv_2669|M.gilvum_PYR-GCK DCGRGVLQRAAAVGVGANQISALLLTHLHSDHIADLGDVLITRWVSNFAP
Mvan_3908|M.vanbaalenii_PYR-1 DCGRGVLQRLAAVGVGANNITALLLTHLHSDHIADLGDVLITRWVSNFAP
MSMEG_4568|M.smegmatis_MC2_155 DCGRGVLQRLAAAGSSASQLSALLLTHLHSDHIADLGDVIITRWVSTFTP
MAV_1774|M.avium_104 DCGRGVLQRAAAVGVGAAGLSTLLLTHLHSDHVGDLGDVLITRWVSTFTP
MUL_3670|M.ulcerans_Agy99 DCGRGVLQRAAAVGVGAAGLSAVLLTHLHSDHIAELGDVLITSWVTNFAA
TH_1457|M.thermoresistible__bu DCGRGVQQRMAGAETSATALTALLLTHLHSDHIADLGDLLITRWISNFDP
MLBr_01173|M.leprae_Br4923 DFGGGVLGALQRHAD--PGSVHVLLSHLHADHCLDMPGLFVWRRYHPTRP
MAB_1483|M.abscessus_ATCC_1997 DFGGGVLGSLQRFAD--PGSVSVLLSHLHADHCLDLPGLFVWRRYHPNPP
* * * ::::***:** : ..:: .
Mb3825|M.bovis_AF2122/97 GRAPVLVYGPGPAGGLPPSEVGNPNPATVNPANPTPGLAAATEALHRAFA
Rv3796|M.tuberculosis_H37Rv GRAPVLVYGPGPAGGLPPSEVGNPNPATVNPANPTPGLAAATEALHRAFA
MMAR_5358|M.marinum_M GRAPIPVYGPGPAGGLPPSEIGNKNPATVNPANPTPGLAATTEALHQAFA
Mflv_2669|M.gilvum_PYR-GCK DLPPLPIIGP-------------------------PGTAEVVENMLKAFS
Mvan_3908|M.vanbaalenii_PYR-1 DLAPLPIIGP-------------------------PGTAEVVENTLKAFG
MSMEG_4568|M.smegmatis_MC2_155 DAPPLPIIGP-------------------------PGTAEVVEATLKAFG
MAV_1774|M.avium_104 DPVPLPIIGP-------------------------PGTAELVAATLNALR
MUL_3670|M.ulcerans_Agy99 DPAPLQVIGP-------------------------PGTAETVEAMLKAFG
TH_1457|M.thermoresistible__bu QLPPLPIIGP-------------------------PGTAEVVSATLRAFG
MLBr_01173|M.leprae_Br4923 VGK-ALLYGP-------------------------DDTWLRLGAASSPYG
MAB_1483|M.abscessus_ATCC_1997 KGK-AIMYGP-------------------------ADTLVRVGAASAEIG
: ** .
Mb3825|M.bovis_AF2122/97 YTSNIFIRDYGIDNVADLVKVTEIGLPPGSDYRNRAPKMSPFSVASDDNV
Rv3796|M.tuberculosis_H37Rv YTSNIFIRDYGIDNVADLVKVTEIGLPPGSDYRNRAPKMSPFSVASDDNV
MMAR_5358|M.marinum_M YSSNIFIRDYGIDNVQDLAKVIEIPVPAGSDYRNTAPKVSPFPVVSDDNV
Mflv_2669|M.gilvum_PYR-GCK FD-----IGYRIAHHDDLTTPPPVEVEEVTDG----------VVWGRDEV
Mvan_3908|M.vanbaalenii_PYR-1 FD-----IGYRIAHHADLTTPPPVEVEEVTEG----------VVWGRDEV
MSMEG_4568|M.smegmatis_MC2_155 HD-----IGYRIAHHDDLTAPPPVEVHEHTEG----------VVWDRDGV
MAV_1774|M.avium_104 HD-----IGYRIAHHADLNAPPAVDVREHTDG----------PVWDRDGV
MUL_3670|M.ulcerans_Agy99 RD-----IGYRIAHHADLNAPPPIEVHEYTDG----------TVWDRDGV
TH_1457|M.thermoresistible__bu HD-----IGYRMKHHADLTTPPQVDVKEATEG----------VVWDVDGV
MLBr_01173|M.leprae_Br4923 GE---------IDDCSDIFDVRHWVDGEPVPLG-----------------
MAB_1483|M.abscessus_ATCC_1997 GE---------VDDFTDIFDVFPWADGEPVQFG-----------------
: . *:
Mb3825|M.bovis_AF2122/97 SVTATLVSHYDVYPAFGFRFDLKKSGVSVTFSGDTTKSDNLITLAQGTDI
Rv3796|M.tuberculosis_H37Rv SVTATLVSHYDVYPAFGFRFDLKKSGVSVTFSGDTTKSDNLITLAQGTDI
MMAR_5358|M.marinum_M SVTTTLVPHYDVYPAFAFRFDVKDPAVSITFSGDTTKSDNLVALANGTDI
Mflv_2669|M.gilvum_PYR-GCK SIRVGPTDHRPVTPTIGFRIEHHG--ASVVLAGDTVPCRGLDKLAAGAGA
Mvan_3908|M.vanbaalenii_PYR-1 SIRVGPTDHRPVTPTIGFRIEHNG--ASVVLAGDTVPCRGLDELAAGAGA
MSMEG_4568|M.smegmatis_MC2_155 VIRVGPTDHRPVTPTIAFRVEHAD--ASVVAAGDSVPCATLDALATGAGA
MAV_1774|M.avium_104 SIRVAPTDHRPVAPTIGFRVDYQG--ASVVLAGDTVPCAGLDELAAGAGA
MUL_3670|M.ulcerans_Agy99 AIRVAPTDHRPVAPTIGFRVEFDG--ASAVLAGGTVPCPSLDELAAGAGA
TH_1457|M.thermoresistible__bu RIRVAPTDHRPVTPTIGFRVEHDG--ASVVLAGDTVPCESLDELAAGAGA
MLBr_01173|M.leprae_Br4923 ALMIMPRLVAHPTESYGLRITDPS-GASLVYSGDTGSCDQLVELARGADV
MAB_1483|M.abscessus_ATCC_1997 SLTVTPTRVAHPPESYGLRIEDSS-GTVLAYSGDTGICDAVVDLARGADV
: : .:*. . . :*.: . : ** *:.
Mb3825|M.bovis_AF2122/97 LVHEAVFSLDTAYFGNAFPPNYLVNSHISAEQVGEVAAAAKPKQLILSHY
Rv3796|M.tuberculosis_H37Rv LVHEAVFSLDTAYFGNAFPPNYLVNSHTSAEQVGEVAAAAKPKQLILSHY
MMAR_5358|M.marinum_M LVHEAMFSLDTAYYGNVFPPDYLPKSHTSAEQVGEVAAVVKPKHLILSHY
Mflv_2669|M.gilvum_PYR-GCK LVHTVIRRDLIEALP-MQRIRDICDYHSSVEQAAETATRAGVGILILTHY
Mvan_3908|M.vanbaalenii_PYR-1 LVHTVIRPDLIEAMP-VQRIRDICDYHSSVEQAADTATRAGVGILILTHY
MSMEG_4568|M.smegmatis_MC2_155 LIHTVIRKDIIETLP-QQRIRDICDYHSSVQEAAATAARAGVGILILTHY
MAV_1774|M.avium_104 LVHTVIRKDIVATIP-QQRLQDICDYHSSVEQAAATAARAGVGTLVMTHY
MUL_3670|M.ulcerans_Agy99 LVHTVIRKDIITNFP-QQRVKDICDYHSSVQEAAATAARAGVGTLVMTHY
TH_1457|M.thermoresistible__bu MVHTVIRKELIAQLP-QQRIREICEYHSSPQEAGATAERAGVGILILTHY
MLBr_01173|M.leprae_Br4923 FLCEASWTHSP-DRP--------PNLHLSGTEAGRAAAQASVRELLLTHI
MAB_1483|M.abscessus_ATCC_1997 FLCEASWTHMPGHRP--------PDLHLSGTEAGQIATRAGVKELLLTHI
:: . . * * :.. * . *:::*
Mb3825|M.bovis_AF2122/97 APDDLP--DSQWLDKIKKNYSGMTTIARDGQVFAL-------------
Rv3796|M.tuberculosis_H37Rv APDDLP--DSQWLDKIKKNYSGMTTIARDGQVFAL-------------
MMAR_5358|M.marinum_M APDDLP--DSQWLDKINQNYSGRTTVAKDGQIFAL-------------
Mflv_2669|M.gilvum_PYR-GCK VPTLQPGQEDDWRALAATRFDRQIEIGDDLHRVQVHPGVCAKPAG---
Mvan_3908|M.vanbaalenii_PYR-1 VPTLQPGQEEDWRALAASVFDRQIEIGDDLHRVEVHPGVGARPAG---
MSMEG_4568|M.smegmatis_MC2_155 VPAIAPGTEDQWRELAATEFDRQIEVGADLHRVEVHPGVCVKPAG---
MAV_1774|M.avium_104 VPALVAGQEEQWRALAAREFAGRVELGDDLHRVQVDAPS---------
MUL_3670|M.ulcerans_Agy99 VPAIIAGQEDQWRALAATEFGGRIELGNDLHRVEVHAR----------
TH_1457|M.thermoresistible__bu LPPVQPGQEDEWRAQAATTFSRQIEVGDDLHRVQVHPGVGSARFGTSP
MLBr_01173|M.leprae_Br4923 PPWTSR---EDVISEAKAEFDGPVHAVVSGETFDIQAPERV-------
MAB_1483|M.abscessus_ATCC_1997 PPWTSR---EDVIAEAKSAFDGPVHAVVAGENIDL-------------
* .: : . . :