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PPNPQRRAQILDAAIDILADVGVGGLTHRQVDDRAGLPAGTTSNYFRTRQALLEATASRTVDLHWQRVQV LRSAVGSLSRDGVKALMTKMLTDPDEQFRRNTLARFELFMEGTRRPELQPFLVELQRAAVKSATLIFEAA GFAPTPEQMDQLSRLLNGYVFSHLTLPGDDDPAALVDRLLPAYFDA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_5226 | - | - | 100% (187) | DeoR family transcriptional regulator |
| M. marinum M | MMAR_1611 | - | 3e-09 | 36.36% (121) | transcriptional regulatory protein |
| M. marinum M | MMAR_4918 | - | 2e-07 | 27.42% (186) | hypothetical protein MMAR_4918 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3093 | - | 6e-10 | 32.16% (171) | DeoR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_3484 | - | 4e-12 | 40.52% (116) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3066 | - | 6e-10 | 32.16% (171) | DeoR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0969 | - | 8e-14 | 31.28% (179) | putative transcriptional regulator, TetR |
| M. avium 104 | MAV_2985 | - | 7e-18 | 41.67% (132) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_0656 | - | 2e-16 | 44.96% (129) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_4019 | - | 6e-12 | 33.62% (116) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_4301 | - | 1e-103 | 99.47% (187) | DeoR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0389 | - | 3e-12 | 39.64% (111) | hypothetical protein Mvan_0389 |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_2985|M.avium_104 ------MDKRRKPNPAERRRDLCDAAIRLLADDGAKGLSHLKVDRKAGVP
MSMEG_0656|M.smegmatis_MC2_155 ------MG--RKQNPEQRRRELCDAAIRLLADEGIKGLTHLKVDRTAGVP
Mvan_0389|M.vanbaalenii_PYR-1 ---MTRVDSRRRPNAAQRRHQLCDAANTLLAEDGPRGLSHLKVDRRAGVP
Mflv_3484|M.gilvum_PYR-GCK ----MTTSPPRKRDGDQRRRELCDAGIQVLAEYGSRGLTHAQVDRCAKVP
Mb3093|M.bovis_AF2122/97 ---MTAGSDRRPRDPAGRRQAIVEAAERVIARQGLGGLSHRRVAAEANVP
Rv3066|M.tuberculosis_H37Rv ---MTAGSDRRPRDPAGRRQAIVEAAERVIARQGLGGLSHRRVAAEANVP
MMAR_5226|M.marinum_M -----------MPPNPQRRAQILDAAIDILADVGVGGLTHRQVDDRAGLP
MUL_4301|M.ulcerans_Agy99 -----------MPPNPQRRAQILDAAIDILADVGVGGLTHRQVDDRAGLP
TH_4019|M.thermoresistible__bu MVDAGETTDGRRARGQRRRAEIIDATLAVVERDGAAGVTHRAVAAEAGIP
MAB_0969|M.abscessus_ATCC_1997 ----------MEEQPRGRRAEVLAAAIEVAGTMGIGGLTYRSVDAAANVP
** : * : * *::: * * :*
MAV_2985|M.avium_104 DGTTSFYFRTRSALLRAAAERLAELDLAELQEIAD--SSGPGPSPSR-LS
MSMEG_0656|M.smegmatis_MC2_155 DGTTSFYFRTSSALLHAVAGRVAELDLQDLTAATE--PPAPGENPAAGLA
Mvan_0389|M.vanbaalenii_PYR-1 DGTTSFYYRTRVALLQGVADHLARYDAEAFAQAFDDVPDGAGDDLLPMLA
Mflv_3484|M.gilvum_PYR-GCK EGTASYYFRTRAALLRGVGDRVAEIDVANLRSLAD--RPLDTNAPFAHLA
Mb3093|M.bovis_AF2122/97 VGSTTYYFNDLDALREAALAHAANASADLLAQWRS--DLDKDRDLAATLA
Rv3066|M.tuberculosis_H37Rv VGSTTYYFNDLDALREAALAHAANASADLLAQWRS--DLDKDRDLAATLA
MMAR_5226|M.marinum_M AGTTSNYFRTRQALLEATASRTVDLHWQRVQVLRS-AVGSLSRDGVKALM
MUL_4301|M.ulcerans_Agy99 AGTTSNYFRTRQALLEATASRTVDLHWQRVQVLRS-AVGSLSRDGVKALM
TH_4019|M.thermoresistible__bu ASLTAYYFATLDDLLVAALSSVADGYTERIREIIE-----RPGDRLRGLA
MAB_0969|M.abscessus_ATCC_1997 SGTTSNHFRTRDALLLGAILEIEKLRRAFWRALVT-EINPTTVSDLVGIG
. :: :: * .. :
MAV_2985|M.avium_104 QVVAQAGADPQLYRTRARYELTLQATRDPALAAILQQATDAFTKLHREIL
MSMEG_0656|M.smegmatis_MC2_155 ALVMRAADGPGFVRSRARLELAMPSSRDPGLAQVFALHQQRFVDMHRDVV
Mvan_0389|M.vanbaalenii_PYR-1 EQVLLVRDEPHLSRTRARLELTMLAKGDAGIAAGFQQVSESYRALTERLV
Mflv_3484|M.gilvum_PYR-GCK ELTLMQSQGRGLMLNRARHELLLNAVRDPELSGPAQGLVSEVITLTRTAI
Mb3093|M.bovis_AF2122/97 RLTTVYLADQDRYRTLN--ELYMAAAHRPELQRLARLWPDGLLALLEPRI
Rv3066|M.tuberculosis_H37Rv RLTTVYLADQDRYRTLN--ELYMAAAHRPELQRLARLWPDGLLALLEPRI
MMAR_5226|M.marinum_M TKMLTDPDEQFRRNTLARFELFMEGTRRPELQPFLVELQRAAVKSATLIF
MUL_4301|M.ulcerans_Agy99 TKMLTDPDEQFRRNTLARFELFMEGTRRPELQPFLVELQRAAVKSATLIF
TH_4019|M.thermoresistible__bu ELIVES-AGPGRERALAERELSTLAARRPALQPVARRWRDNVAELASTLT
MAB_0969|M.abscessus_ATCC_1997 TAYANGAVGAMSTRVRAYMALLMEGWSHPELREPLQRGRDAQIPRTLHLM
* . . :
MAV_2985|M.avium_104 VQLMPHGAQ-LDPAVVEDLSNVTLTFINGLLQRLVHGDRIVDSPEQ-LDG
MSMEG_0656|M.smegmatis_MC2_155 QRLSPD----ADPAEVAERTYVLLTFISGLLLALSRGDRTIGSAEQ-LEA
Mvan_0389|M.vanbaalenii_PYR-1 TAMQNGLTAPLDRSLLDEQVSVVLTYLSGLVFAFANGSTEPMTSRD-IQR
Mflv_3484|M.gilvum_PYR-GCK ARLQPDT---TDPDLLDAQASAVTTFIAGVFLRFVAGDQTFNDPDK-LSR
Mb3093|M.bovis_AF2122/97 GRRAAN--------------AVTVFFDGATLHALITG--TPLSTDE-LTD
Rv3066|M.tuberculosis_H37Rv GRRAAN--------------AVTVFFDGATLHALITG--TPLSTDE-LTD
MMAR_5226|M.marinum_M EAAGFAP------------TPEQMDQLSRLLNGYVFSHLTLPGDDD-PAA
MUL_4301|M.ulcerans_Agy99 EAAGFAP------------TPEQMDQLIRLLNGYVFSHLTLPGDDD-PAA
TH_4019|M.thermoresistible__bu DDPQAIA--------------ALVAASDGLCTAILIDN--APADVD-FAH
MAB_0969|M.abscessus_ATCC_1997 CKVDPKTP--------QLHAEIFQDYLTGIIYQQLANPVADFNPRPGIEA
.
MAV_2985|M.avium_104 ILSAIATGILKSPDKGRLTRTGGQAAARRRADDSE
MSMEG_0656|M.smegmatis_MC2_155 IICSLCRGGPQ-PEQG-------------------
Mvan_0389|M.vanbaalenii_PYR-1 QIRAVVIGVAAERLSQTS-----------------
Mflv_3484|M.gilvum_PYR-GCK QLQAIADAVAHDYGESN------------------
Mb3093|M.bovis_AF2122/97 AIARLVADGPEQREVGQSAHAGRTPD---------
Rv3066|M.tuberculosis_H37Rv AIARLVADGPEQREVGQSAHAGRTPD---------
MMAR_5226|M.marinum_M LVDRLLPAYFDA-----------------------
MUL_4301|M.ulcerans_Agy99 LVDRLLPAYFDA-----------------------
TH_4019|M.thermoresistible__bu GVLRRALGVPAEHQP--------------------
MAB_0969|M.abscessus_ATCC_1997 LLTALVTPPQTPRAAQR------------------
: