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DKRRKPNPAERRRDLCDAAIRLLADDGAKGLSHLKVDRKAGVPDGTTSFYFRTRSALLRAAAERLAELDL AELQEIADSSGPGPSPSRLSQVVAQAGADPQLYRTRARYELTLQATRDPALAAILQQATDAFTKLHREIL VQLMPHGAQLDPAVVEDLSNVTLTFINGLLQRLVHGDRIVDSPEQLDGILSAIATGILKSPDKGRLTRTG GQAAARRRADDSE*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2985 | - | - | 100% (224) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_5252 | - | 3e-36 | 44.44% (180) | hypothetical protein MAV_5252 |
| M. avium 104 | MAV_4178 | - | 2e-31 | 41.24% (177) | hypothetical protein MAV_4178 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3093 | - | 3e-12 | 30.04% (223) | DeoR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_3484 | - | 3e-33 | 39.49% (195) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3066 | - | 3e-12 | 30.04% (223) | DeoR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4710c | - | 5e-16 | 36.30% (135) | TetR family transcriptional regulator |
| M. marinum M | MMAR_5226 | - | 1e-17 | 41.67% (132) | DeoR family transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_0656 | - | 1e-48 | 51.55% (194) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_4019 | - | 1e-12 | 28.00% (175) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_4301 | - | 8e-18 | 41.67% (132) | DeoR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0389 | - | 4e-36 | 42.16% (204) | hypothetical protein Mvan_0389 |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_2985|M.avium_104 ------MDKRRKPNPAERRRDLCDAAIRLLADDGAKGLSHLKVDRKAGVP
MSMEG_0656|M.smegmatis_MC2_155 ------MG--RKQNPEQRRRELCDAAIRLLADEGIKGLTHLKVDRTAGVP
Mvan_0389|M.vanbaalenii_PYR-1 ---MTRVDSRRRPNAAQRRHQLCDAANTLLAEDGPRGLSHLKVDRRAGVP
Mflv_3484|M.gilvum_PYR-GCK ----MTTSPPRKRDGDQRRRELCDAGIQVLAEYGSRGLTHAQVDRCAKVP
MMAR_5226|M.marinum_M -----------MPPNPQRRAQILDAAIDILADVGVGGLTHRQVDDRAGLP
MUL_4301|M.ulcerans_Agy99 -----------MPPNPQRRAQILDAAIDILADVGVGGLTHRQVDDRAGLP
Mb3093|M.bovis_AF2122/97 ---MTAGSDRRPRDPAGRRQAIVEAAERVIARQGLGGLSHRRVAAEANVP
Rv3066|M.tuberculosis_H37Rv ---MTAGSDRRPRDPAGRRQAIVEAAERVIARQGLGGLSHRRVAAEANVP
MAB_4710c|M.abscessus_ATCC_199 -------------MADDRRTQLADAGLAVLAAGGARGLTHRAVDRSAELP
TH_4019|M.thermoresistible__bu MVDAGETTDGRRARGQRRRAEIIDATLAVVERDGAAGVTHRAVAAEAGIP
** : :* :: * *::* * * :*
MAV_2985|M.avium_104 DGTTSFYFRTRSALLRAAAERLAELDLAELQEIAD--SSGPGPSPSR-LS
MSMEG_0656|M.smegmatis_MC2_155 DGTTSFYFRTSSALLHAVAGRVAELDLQDLTAATE--PPAPGENPAAGLA
Mvan_0389|M.vanbaalenii_PYR-1 DGTTSFYYRTRVALLQGVADHLARYDAEAFAQAFDDVPDGAGDDLLPMLA
Mflv_3484|M.gilvum_PYR-GCK EGTASYYFRTRAALLRGVGDRVAEIDVANLRSLAD--RPLDTNAPFAHLA
MMAR_5226|M.marinum_M AGTTSNYFRTRQALLEATASRTVDLHWQRVQVLRS-AVGSLSRDGVKALM
MUL_4301|M.ulcerans_Agy99 AGTTSNYFRTRQALLEATASRTVDLHWQRVQVLRS-AVGSLSRDGVKALM
Mb3093|M.bovis_AF2122/97 VGSTTYYFNDLDALREAALAHAANASADLLAQWRS--DLDKDRDLAATLA
Rv3066|M.tuberculosis_H37Rv VGSTTYYFNDLDALREAALAHAANASADLLAQWRS--DLDKDRDLAATLA
MAB_4710c|M.abscessus_ATCC_199 EGSTSYYLRTRVALLQACATRLGERTMTAVVPLAE--PVHLDISALTQLA
TH_4019|M.thermoresistible__bu ASLTAYYFATLDDLLVAALSSVADGYTERIREIIE-----RPGDRLRGLA
. :: * * . . . *
MAV_2985|M.avium_104 QVVAQAGADPQLYRTRARYELTLQATRDPALAAILQQATDAFTKLHREIL
MSMEG_0656|M.smegmatis_MC2_155 ALVMRAADGPGFVRSRARLELAMPSSRDPGLAQVFALHQQRFVDMHRDVV
Mvan_0389|M.vanbaalenii_PYR-1 EQVLLVRDEPHLSRTRARLELTMLAKGDAGIAAGFQQVSESYRALTERLV
Mflv_3484|M.gilvum_PYR-GCK ELTLMQSQGRGLMLNRARHELLLNAVRDPELSGPAQGLVSEVITLTRTAI
MMAR_5226|M.marinum_M TKMLTDPDEQFRRNTLARFELFMEGTRRPELQPFLVELQRAAVKSATLIF
MUL_4301|M.ulcerans_Agy99 TKMLTDPDEQFRRNTLARFELFMEGTRRPELQPFLVELQRAAVKSATLIF
Mb3093|M.bovis_AF2122/97 RLTTVYLADQDRYRTLN--ELYMAAAHRPELQRLARLWPDGLLALLEPRI
Rv3066|M.tuberculosis_H37Rv RLTTVYLADQDRYRTLN--ELYMAAAHRPELQRLARLWPDGLLALLEPRI
MAB_4710c|M.abscessus_ATCC_199 VRAVRAWIADGGVLVLARHELLLESAQHPQMRSVLDAATDHIRGLLERRL
TH_4019|M.thermoresistible__bu ELIVES-AGPGRERALAERELSTLAARRPALQPVARRWRDNVAELASTLT
** . . :
MAV_2985|M.avium_104 VQLMPHGAQ-LDPAVVEDLSNVTLTFINGLLQRLVHGDRIVDSPEQLDGI
MSMEG_0656|M.smegmatis_MC2_155 QRLSPD----ADPAEVAERTYVLLTFISGLLLALSRGDRTIGSAEQLEAI
Mvan_0389|M.vanbaalenii_PYR-1 TAMQNGLTAPLDRSLLDEQVSVVLTYLSGLVFAFANGSTEPMTSRDIQRQ
Mflv_3484|M.gilvum_PYR-GCK ARLQPDT---TDPDLLDAQASAVTTFIAGVFLRFVAGDQTFNDPDKLSRQ
MMAR_5226|M.marinum_M EAAGFAP--------TPEQMDQLSRLLNGYVFSHLTLPGDDDPAALVDRL
MUL_4301|M.ulcerans_Agy99 EAAGFAP--------TPEQMDQLIRLLNGYVFSHLTLPGDDDPAALVDRL
Mb3093|M.bovis_AF2122/97 G---------------RRAANAVTVFFDGATLHALITGTPLSTDELTDAI
Rv3066|M.tuberculosis_H37Rv G---------------RRAANAVTVFFDGATLHALITGTPLSTDELTDAI
MAB_4710c|M.abscessus_ATCC_199 IALGISD--------AAERTGDLIACLDGIALAYAVRG--VAAEDALRRS
TH_4019|M.thermoresistible__bu DD--------------PQAIAALVAASDGLCTAILIDNAPADVDFAHGVL
*
MAV_2985|M.avium_104 LSAIATGILKSPDKGRLTRTGGQAAARRRADDSE
MSMEG_0656|M.smegmatis_MC2_155 ICSLCRGGPQ-PEQG-------------------
Mvan_0389|M.vanbaalenii_PYR-1 IRAVVIGVAAERLSQTS-----------------
Mflv_3484|M.gilvum_PYR-GCK LQAIADAVAHDYGESN------------------
MMAR_5226|M.marinum_M LPAYFDA---------------------------
MUL_4301|M.ulcerans_Agy99 LPAYFDA---------------------------
Mb3093|M.bovis_AF2122/97 ARLVADGPEQREVGQSAHAGRTPD----------
Rv3066|M.tuberculosis_H37Rv ARLVADGPEQREVGQSAHAGRTPD----------
MAB_4710c|M.abscessus_ATCC_199 VTRVVSGLLAVRD---------------------
TH_4019|M.thermoresistible__bu RRALGVPAEHQP----------------------