For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MTTSPPRKRDGDQRRRELCDAGIQVLAEYGSRGLTHAQVDRCAKVPEGTASYYFRTRAALLRGVGDRVAE IDVANLRSLADRPLDTNAPFAHLAELTLMQSQGRGLMLNRARHELLLNAVRDPELSGPAQGLVSEVITLT RTAIARLQPDTTDPDLLDAQASAVTTFIAGVFLRFVAGDQTFNDPDKLSRQLQAIADAVAHDYGESN
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3484 | - | - | 100% (207) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0348 | - | 1e-20 | 36.11% (180) | hypothetical protein Mflv_0348 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3093 | - | 4e-09 | 32.02% (178) | DeoR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3066 | - | 4e-09 | 32.02% (178) | DeoR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4710c | - | 1e-17 | 44.35% (115) | TetR family transcriptional regulator |
| M. marinum M | MMAR_5226 | - | 5e-12 | 40.52% (116) | DeoR family transcriptional regulator |
| M. avium 104 | MAV_4178 | - | 3e-60 | 65.91% (176) | hypothetical protein MAV_4178 |
| M. smegmatis MC2 155 | MSMEG_0656 | - | 3e-33 | 41.21% (182) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_4019 | - | 1e-10 | 29.44% (180) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_4301 | - | 3e-12 | 40.52% (116) | DeoR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0389 | - | 1e-24 | 36.18% (199) | hypothetical protein Mvan_0389 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3484|M.gilvum_PYR-GCK ----MTTSPPRKRDGDQRRRELCDAGIQVLAEYGSRGLTHAQVDRCAKVP
MAV_4178|M.avium_104 ----------------------------MLAEHGSRGLTHGQVDRYAGVP
MSMEG_0656|M.smegmatis_MC2_155 --------MGRKQNPEQRRRELCDAAIRLLADEGIKGLTHLKVDRTAGVP
Mvan_0389|M.vanbaalenii_PYR-1 ---MTRVDSRRRPNAAQRRHQLCDAANTLLAEDGPRGLSHLKVDRRAGVP
MMAR_5226|M.marinum_M -----------MPPNPQRRAQILDAAIDILADVGVGGLTHRQVDDRAGLP
MUL_4301|M.ulcerans_Agy99 -----------MPPNPQRRAQILDAAIDILADVGVGGLTHRQVDDRAGLP
Mb3093|M.bovis_AF2122/97 ---MTAGSDRRPRDPAGRRQAIVEAAERVIARQGLGGLSHRRVAAEANVP
Rv3066|M.tuberculosis_H37Rv ---MTAGSDRRPRDPAGRRQAIVEAAERVIARQGLGGLSHRRVAAEANVP
MAB_4710c|M.abscessus_ATCC_199 -------------MADDRRTQLADAGLAVLAAGGARGLTHRAVDRSAELP
TH_4019|M.thermoresistible__bu MVDAGETTDGRRARGQRRRAEIIDATLAVVERDGAAGVTHRAVAAEAGIP
:: * *::* * * :*
Mflv_3484|M.gilvum_PYR-GCK EGTASYYFRTRAALLRGVGDRVAEIDVANLRSLADRPLD--TNAPFAHLA
MAV_4178|M.avium_104 EGTTSYYYRTRAALLQGVGKRVAEIDVANLQSVIDEPLD--PLSPFAHLA
MSMEG_0656|M.smegmatis_MC2_155 DGTTSFYFRTSSALLHAVAGRVAELDLQDLTAATEPPAP--GENPAAGLA
Mvan_0389|M.vanbaalenii_PYR-1 DGTTSFYYRTRVALLQGVADHLARYDAEAFAQAFDDVPDGAGDDLLPMLA
MMAR_5226|M.marinum_M AGTTSNYFRTRQALLEATASRTVDLHWQRVQVLRSAVGS-LSRDGVKALM
MUL_4301|M.ulcerans_Agy99 AGTTSNYFRTRQALLEATASRTVDLHWQRVQVLRSAVGS-LSRDGVKALM
Mb3093|M.bovis_AF2122/97 VGSTTYYFNDLDALREAALAHAANASADLLAQWRSDLDK--DRDLAATLA
Rv3066|M.tuberculosis_H37Rv VGSTTYYFNDLDALREAALAHAANASADLLAQWRSDLDK--DRDLAATLA
MAB_4710c|M.abscessus_ATCC_199 EGSTSYYLRTRVALLQACATRLGERTMTAVVPLAEPVHL--DISALTQLA
TH_4019|M.thermoresistible__bu ASLTAYYFATLDDLLVAALSSVADGYTERIREIIERPGD-----RLRGLA
. :: * * . . . *
Mflv_3484|M.gilvum_PYR-GCK ELTLMQSQGRGLMLNRARHELLLNAVRDPELSGPAQGLVSEVITLTRTAI
MAV_4178|M.avium_104 RLTMMQASGPGLMLNRARHELLLGAARDPGLAETSQVFAGRINSMARDAI
MSMEG_0656|M.smegmatis_MC2_155 ALVMRAADGPGFVRSRARLELAMPSSRDPGLAQVFALHQQRFVDMHRDVV
Mvan_0389|M.vanbaalenii_PYR-1 EQVLLVRDEPHLSRTRARLELTMLAKGDAGIAAGFQQVSESYRALTERLV
MMAR_5226|M.marinum_M TKMLTDPDEQFRRNTLARFELFMEGTRRPELQPFLVELQRAAVKSATLIF
MUL_4301|M.ulcerans_Agy99 TKMLTDPDEQFRRNTLARFELFMEGTRRPELQPFLVELQRAAVKSATLIF
Mb3093|M.bovis_AF2122/97 RLTTVYLADQDRYRTLN--ELYMAAAHRPELQRLARLWPDGLLALLEPRI
Rv3066|M.tuberculosis_H37Rv RLTTVYLADQDRYRTLN--ELYMAAAHRPELQRLARLWPDGLLALLEPRI
MAB_4710c|M.abscessus_ATCC_199 VRAVRAWIADGGVLVLARHELLLESAQHPQMRSVLDAATDHIRGLLERRL
TH_4019|M.thermoresistible__bu ELIVES-AGPGRERALAERELSTLAARRPALQPVARRWRDNVAELASTLT
** . . :
Mflv_3484|M.gilvum_PYR-GCK ARLQ---PDTTDPDLLDAQASAVTTFIAGVFLRFVAGDQTFNDPDKLSRQ
MAV_4178|M.avium_104 AHLQ---PDIRDPALLDAQTTAVTTFIAGVFTRLAAGDRNVGDAEQLAHL
MSMEG_0656|M.smegmatis_MC2_155 QRLS---PDA-DPAEVAERTYVLLTFISGLLLALSRGDRTIGSAEQLEAI
Mvan_0389|M.vanbaalenii_PYR-1 TAMQNGLTAPLDRSLLDEQVSVVLTYLSGLVFAFANGSTEPMTSRDIQRQ
MMAR_5226|M.marinum_M EAAG--------FAPTPEQMDQLSRLLNGYVFSHLTLPGDDDPAALVDRL
MUL_4301|M.ulcerans_Agy99 EAAG--------FAPTPEQMDQLIRLLNGYVFSHLTLPGDDDPAALVDRL
Mb3093|M.bovis_AF2122/97 GRRAAN------AVTVFFDGATLHALITGTPLSTDELTDAIARLVADGPE
Rv3066|M.tuberculosis_H37Rv GRRAAN------AVTVFFDGATLHALITGTPLSTDELTDAIARLVADGPE
MAB_4710c|M.abscessus_ATCC_199 IALG--------ISDAAERTGDLIACLDGIALAYAVRG--VAAEDALRRS
TH_4019|M.thermoresistible__bu DDPQ--------------AIAALVAASDGLCTAILIDNAPADVDFAHGVL
: *
Mflv_3484|M.gilvum_PYR-GCK LQAIADAVAHDYGESN-
MAV_4178|M.avium_104 LEAVATAVALRAQRS--
MSMEG_0656|M.smegmatis_MC2_155 ICSLCRGGPQPEQG---
Mvan_0389|M.vanbaalenii_PYR-1 IRAVVIGVAAERLSQTS
MMAR_5226|M.marinum_M LPAYFDA----------
MUL_4301|M.ulcerans_Agy99 LPAYFDA----------
Mb3093|M.bovis_AF2122/97 QREVGQSAHAGRTPD--
Rv3066|M.tuberculosis_H37Rv QREVGQSAHAGRTPD--
MAB_4710c|M.abscessus_ATCC_199 VTRVVSGLLAVRD----
TH_4019|M.thermoresistible__bu RRALGVPAEHQP-----