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VSLVRVAPQVVADGVGNLARIGSSIGVANAAAAAATTTMVPAGGDEVSVAVVGLFRGLGQDYQLFGAQLE QFHQRFVQILDAARTAYLETETAAAAAVADGQFQVLAEPVQTLGQAWLGSPAGELLDPLVNAPFESLTGR ELIGNGAAGVAGVDGGAGQAGGWLFGDGGPGAAATATSAAGRGGDAGLIGAGGAGGAGWANSGVAMMAGG AGGDGGLVFGDGGPGSPGAASFDPTVAGGAGGPGGDARGIGDGGRGGDGGPGATGAPGGRGSDGGPGGKG GNAGDYGNGGTGGTGGIGGAGGPGSPGQSWGDPGSQGGLGGRGGAGGIGGDGGQLSGSGGAGGIGGEGGH GGAGGDGKDAVESPQFGKAGGPGGDGGRGGLGGFGGDGGAGGHALAPRYHDGAPGAGGVGGDGGAGGNGG RGGDGANGVNAATLASVIGGNGGDGGNGGYGNLGGYGGLSGDGSTRAGQGVAGIDGDGGDGGNGGNGSTT DHGVIPQGWGGNGGNGGRGFNGGDGGDGGNGGSGPTTLRLFGRVGGDGGDGGRGGDAYGGNAGWGGDGGN GGRGAYGSGLIPPARGGDGGNGGDGGDLYINGVMYQHGGAGFDGLPGEPPDIPPIGGLGGKGGSGGLGPH AP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_5038 | - | - | 100% (633) | PE-PGRS family protein |
| M. marinum M | MMAR_4822 | - | 0.0 | 77.85% (632) | PE-PGRS family protein |
| M. marinum M | MMAR_5306 | - | 0.0 | 53.50% (686) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1121 | PE_PGRS22 | 1e-133 | 42.41% (731) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 6e-99 | 46.11% (514) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv1091 | PE_PGRS22 | 1e-133 | 42.23% (734) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01556 | infB | 6e-11 | 28.97% (290) | translation initiation factor IF-2 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 2e-34 | 31.26% (435) | hypothetical protein MAB_4284c |
| M. avium 104 | MAV_4827 | - | 4e-21 | 42.44% (172) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 1e-83 | 37.22% (720) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 5e-43 | 36.52% (345) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_0391 | - | 0.0 | 66.77% (638) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-97 | 45.45% (506) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_5038|M.marinum_M --------------------------------------------------
MUL_0391|M.ulcerans_Agy99 --------------------------------------------------
Mb1121|M.bovis_AF2122/97 --------------------------------------------------
Rv1091|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 --------------------------------------------------
MMAR_5038|M.marinum_M -----------------MVSLVRVAPQVVADGVGNLARIGSSIGVANAAA
MUL_0391|M.ulcerans_Agy99 ------------------MSLVRVAPQVVADGVGNLARIGSSIGVANAAA
Mb1121|M.bovis_AF2122/97 ------------------MSFVIAAPEALVAVASDLAGIGSALAEANAAA
Rv1091|M.tuberculosis_H37Rv ------------------MSFVIAAPEALVAVASDLAGIGSALAEANAAA
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---------------MSIIDFILNLFRDPVEAASYVADPEAALANAGLSA
MAV_4827|M.avium_104 ----------------------MNIVLGVSMAPSSIQMVVLEGEYADGAT
MLBr_01556|M.leprae_Br4923 -------MAGKARVHELAKELGVTSKEVLARLNEQGEFVKSASSTVEAPV
MMAR_5038|M.marinum_M AAAT--------------------------------TTMVPAGGDEVSVA
MUL_0391|M.ulcerans_Agy99 AAAT--------------------------------TTMVPAGGDEVS--
Mb1121|M.bovis_AF2122/97 LAPT--------------------------------TALLAAGADEVSAA
Rv1091|M.tuberculosis_H37Rv LAPT--------------------------------TALLAAGADEVSAA
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 VSAAQVG------------------------------AVMPVVAESVASN
MAV_4827|M.avium_104 VEED---------------------------------AIDVTGADDAATA
MLBr_01556|M.leprae_Br4923 ARRLRESFG-------------------------GIKPAADKGAEQVATK
MMAR_5038|M.marinum_M VVGLFRGLGQDYQLFGAQLEQFHQRFVQILDAARTAYLETETAAAAAVAD
MUL_0391|M.ulcerans_Agy99 ---------------------------------------------AAVAD
Mb1121|M.bovis_AF2122/97 IAALFGAHGQAYQT------------------------------VSAQAS
Rv1091|M.tuberculosis_H37Rv IAALFGAHGQAYQT------------------------------VSAQAS
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSD-------------PAMRTTVNPQAQ
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----------------------------------------------YGYQ
MAV_4827|M.avium_104 S-------------------------------------------------
MLBr_01556|M.leprae_Br4923 AQAKRLG--------------------------------------ESLDQ
MMAR_5038|M.marinum_M GQFQVLAEPVQTLGQ--------------------AWLGSPAG-------
MUL_0391|M.ulcerans_Agy99 GQFQVLAEPVQTLGQ--------------------AWLASPAG-------
Mb1121|M.bovis_AF2122/97 AFHAQFVQALTGGGG--------------------AYAAAEAANVSAAQS
Rv1091|M.tuberculosis_H37Rv AFHAQFVQALTGGGG--------------------AYAAAEAANVSAAQS
Mflv_5091|M.gilvum_PYR-GCK ---TSLGAAAVDLS------------------------GTSCG-------
Mvan_1264|M.vanbaalenii_PYR-1 ---NNLAASLVDLS------------------------GTSCG-------
MSMEG_0868|M.smegmatis_MC2_155 LPVPTVASAVLDPTQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTIS
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 SQWVNTGNPIHDLSG----------------NLQNYYAAQPDGPSILSPS
MAV_4827|M.avium_104 APDRVISAILGTREG-------------------AADAGLQLSSIGVTWT
MLBr_01556|M.leprae_Br4923 TLDRALDKAVAGNGATTAAPVQVDHSAAVVPIVAGEGPSTAHREELAPPA
MMAR_5038|M.marinum_M --ELLDPLVNAPFES---LTGRELIGNGAAGV----AGVDGGAGQAGGWL
MUL_0391|M.ulcerans_Agy99 --ELLDPLVNAPFES---LTGRELIGNGAAGV----AGVDGGAGQAGGWL
Mb1121|M.bovis_AF2122/97 TDQRLLDLINGPTQA---LLGRPLIGDGANGG----PGQDGGP---GGLL
Rv1091|M.tuberculosis_H37Rv TDQRLLDLINGPTQA---LLGRPLIGDGANGG----PGQDGGP---GGLL
Mflv_5091|M.gilvum_PYR-GCK ---LICNGQDGTGQN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLF
Mvan_1264|M.vanbaalenii_PYR-1 ---LICNGQDGTGQN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLF
MSMEG_0868|M.smegmatis_MC2_155 GQYLIGNGINGTADNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLF
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 LLSPRDNDFLSHNDTDFASHNPIASGNQVMSPSGNVDSFNRGPLLDLSFG
MAV_4827|M.avium_104 DQLEAAALRDALAAR---RIDNVMLVSAFLAAAALAQNVGGAMGYERTAV
MLBr_01556|M.leprae_Br4923 GQPSEQPGVPLPGQQGTPAAPHPGHPGMPTGPHPGPAPKPGGRPPRVGNN
MMAR_5038|M.marinum_M FGDGGPG-AAATATSAAGRGGDAG---LIGAGGAGGAGWANSG-----VA
MUL_0391|M.ulcerans_Agy99 FGDGGPG-AAATATSAAGRGGDAG---LIGAGGAGGAGWANSG-----VA
Mb1121|M.bovis_AF2122/97 YGNGGNGGTSTTAGVAGGNGGAAG---LIGNGGAGGGGGAG---------
Rv1091|M.tuberculosis_H37Rv YGNGGNGGTSTTAGVAGGNGGAAG---LIGNGGAGGGGGAG---------
Mflv_5091|M.gilvum_PYR-GCK GGNGGNG-GNGLGGGNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG
Mvan_1264|M.vanbaalenii_PYR-1 GGNGGNG-GNGLGSGDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG
MSMEG_0868|M.smegmatis_MC2_155 G-NGGNG-GVGWAGLDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVD
TH_3810|M.thermoresistible__bu ------------VDGDGGSGGRTGLFSKLSRGGDGGDGGLG---------
MAB_4284c|M.abscessus_ATCC_199 DLQFGNRDTTAIGDGAVAVGGSNSGPIASGQGSTAVNGDVRDS-------
MAV_4827|M.avium_104 LLVEPDTATLAVVETSDGSIPDVYKQQIRAESYGDAAGQLSAMVAG----
MLBr_01556|M.leprae_Br4923 PFSSAQSVARPIPRPPAPRPSASPSSMSPRPGGAVGGGGPRPPRTG--VP
. *
MMAR_5038|M.marinum_M MMAGGAGGDGGLVFGDGGPGSPGAASFDPTVAGGAGGPGGDARGIGDGG-
MUL_0391|M.ulcerans_Agy99 MMAGGAGGDGGLLLGDGGPGSPGAASFDPTVAGGAGGPGGDARGIGDGG-
Mb1121|M.bovis_AF2122/97 -AAGGNGGAGGWLYGNGGAGGAGGTSVIPGVAGGNGGAGGSAGLWGTGG-
Rv1091|M.tuberculosis_H37Rv -AAGGNGGAGGWLYGNGGAGGAGGTSVIPGVAGGNGGAGGSAGLWGTGG-
Mflv_5091|M.gilvum_PYR-GCK --APGVAGATGATGVTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG-
Mvan_1264|M.vanbaalenii_PYR-1 --APGVAGATGATGVTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG-
MSMEG_0868|M.smegmatis_MC2_155 GGTGGTGGTGGGTGGTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGN
TH_3810|M.thermoresistible__bu ----GNGGHG------GGTGIISLLSLAGNGGNGGNGYRTTDNNALDGG-
MAB_4284c|M.abscessus_ATCC_199 ---NIINADHGSNVGVDQSQTRVGGDYTNVSGHGSADIDKSVTVVDDHS-
MAV_4827|M.avium_104 -LEKLESLPGGLLLVGSGVDVAPLKQVLQTTTFLDVSVAEEPETALARG-
MLBr_01556|M.leprae_Br4923 RPGGGRPGAPVGGRSDAGGGNYRGGGVGALPGGGSGGFRGRPGGGGHGG-
. .
MMAR_5038|M.marinum_M -------------------RGGDGGPGATG------APGGRGSDG-----
MUL_0391|M.ulcerans_Agy99 -------------------RGGDGGPGATG------APGGRGSDG-----
Mb1121|M.bovis_AF2122/97 -------------------AGGDGGNGRSGPVNVAGSAGGNGGAGGAAG-
Rv1091|M.tuberculosis_H37Rv -------------------AGGDGGNGRSGPVNVAGSAGGNGGAGGAAG-
Mflv_5091|M.gilvum_PYR-GCK -------------AVGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG--
Mvan_1264|M.vanbaalenii_PYR-1 -------------AVGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG--
MSMEG_0868|M.smegmatis_MC2_155 GGFGYVLIAGPNVTVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGG
TH_3810|M.thermoresistible__bu -------------------HGGNGGNVGFFSLFNLGGAGGWGGSG-----
MAB_4284c|M.abscessus_ATCC_199 -------------------QRNTTNINDSFNTDRSTNIGSGNTTNTEIG-
MAV_4827|M.avium_104 --------------------AALAAANAPLFASSTAALAYAQDPG-----
MLBr_01556|M.leprae_Br4923 ----------------GGRPGQRGGAAGAFGRPGGAPRRGRKSKRQKRQ-
MMAR_5038|M.marinum_M -----------------GPGGKGGN----------AGDYGNGGTG-----
MUL_0391|M.ulcerans_Agy99 -----------------GPGGKGGN----------AGDYGTGGTG-----
Mb1121|M.bovis_AF2122/97 ---------LFGDAGAGGNGGKGGAGGAAFSINFTAGDGGAGGAG-----
Rv1091|M.tuberculosis_H37Rv ---------LFGDAGAGGNGGKGGAGGAAFSINFTAGDGGAGGAG-----
Mflv_5091|M.gilvum_PYR-GCK --AVGAAG-------AAGTVGTAGATGG----TGTGANGGAGGVG-----
Mvan_1264|M.vanbaalenii_PYR-1 --AIGTAG-------VAGAAGTAGATGG----TGVGGNGGAGQAG-----
MSMEG_0868|M.smegmatis_MC2_155 AILIGANGGTVDGHAIGGNGGNGGNGST----TAAGGNGGTGGTGRVIAE
TH_3810|M.thermoresistible__bu ---------------VDGVDVVGGN-----------PDGGTP--------
MAB_4284c|M.abscessus_ATCC_199 ---------------SHNQANIGTS----------TSAGGSAAVG-----
MAV_4827|M.avium_104 ------------------TGAVDQYSLPDYLYVPVDPEPGDDELAY----
MLBr_01556|M.leprae_Br4923 ------------EYDSMQAPVVGGVRLPHGNGETIRLARGASLSDFAEKI
*
MMAR_5038|M.marinum_M GTG------GIGGAGGPGSPGQSWGDPGSQ--------------------
MUL_0391|M.ulcerans_Agy99 GTG------GIGGAGGPGSPGGTPGAQGFR--------------------
Mb1121|M.bovis_AF2122/97 GSGGHALLWGAGGAGGNGGSGGTGGAGGST--------------------
Rv1091|M.tuberculosis_H37Rv GSGGHALLWGAGGAGGNGGSGGTGGAGGST--------------------
Mflv_5091|M.gilvum_PYR-GCK GVGGTGAAGAAGGAGGLGETGTTGGAGGVG--------------------
Mvan_1264|M.vanbaalenii_PYR-1 GIGGTGAAGAAGQAGTAGETGVTGGVGGIG--------------------
MSMEG_0868|M.smegmatis_MC2_155 GTGSTAEGTATGGDGGHSTGTGIGGNGGIGSVYAYGNNGAVSGTATGGRG
TH_3810|M.thermoresistible__bu -----------GAHGESHTPGVYTDRQGED--------------------
MAB_4284c|M.abscessus_ATCC_199 --GNAGLAGNAGLAGNAGLAGNAGLAGNAG--------------------
MAV_4827|M.avium_104 ---------SAVGEEDAESPTVVIEKLFLP--------------------
MLBr_01556|M.leprae_Br4923 DANPAALVQALFNLGEMVTATQSVGDETLELLG-----------------
MMAR_5038|M.marinum_M --GGLGGRGGAGGI----------------GGDGGQ------LSGSG---
MUL_0391|M.ulcerans_Agy99 --AGDAGNGGVGGI----------------GGDGGH------IKGHG---
Mb1121|M.bovis_AF2122/97 --AGAGGNGGAGGG----------------GGTGGL------LFGNG---
Rv1091|M.tuberculosis_H37Rv --AGAGGNGGAGGG----------------GGTGGL------LFGNG---
Mflv_5091|M.gilvum_PYR-GCK GQGTAGGTGGVGGIGGAG----------STGAVGG-------VGGKG---
Mvan_1264|M.vanbaalenii_PYR-1 GQGTEGGTGGVGGVGGVG----------ATGGAGG-------VGGKG---
MSMEG_0868|M.smegmatis_MC2_155 GDGIDGGTGGAGGMGEIYSGADGEATGISAGGDGGSATGADSLGGRGGTS
TH_3810|M.thermoresistible__bu ------GEDGTG-------------------------------TGIG---
MAB_4284c|M.abscessus_ATCC_199 ----LAGNAGLAGN----------------AGLAGN-------AGLAG--
MAV_4827|M.avium_104 ----EDSEPRRRP---------------------------VLLVGSG---
MLBr_01556|M.leprae_Br4923 ----SEMNYNVQVVS---------------------------PEDEDR--
.
MMAR_5038|M.marinum_M ----GAG----------------------GIGGEG---------------
MUL_0391|M.ulcerans_Agy99 ----GAG----------------------GIGGTGGAGV-----------
Mb1121|M.bovis_AF2122/97 ----GAGGHGAAAGNGLAAGNGVSSSGGGGAGGTGGAGGDGGAGGAGG--
Rv1091|M.tuberculosis_H37Rv ----GAGGHGAAAGNGLAAGNGVSSSGGGGAGGTGGAGGDGGAGGAGG--
Mflv_5091|M.gilvum_PYR-GCK -IQGGQG-------------LQGGKGGDGGAGGKGGDADSMGS-------
Mvan_1264|M.vanbaalenii_PYR-1 -IQGGQG-------------LQGGQGGDGGTGGTGGDATSMGE-------
MSMEG_0868|M.smegmatis_MC2_155 WVQAGYGPTTGGKASGTAKAGHGGKASDGGKGGNGGDALVMAAGATGVAT
TH_3810|M.thermoresistible__bu -----------------------------GRGGNGGS-------------
MAB_4284c|M.abscessus_ATCC_199 ---------------------------NAGLAGNAG--------------
MAV_4827|M.avium_104 -------------------------LAVVGISAVLALEIALAIG------
MLBr_01556|M.leprae_Br4923 ---------------------ELLEPFDLTYGEDQGDEDELQVR------
.
MMAR_5038|M.marinum_M -------------GHGGAGGDGKDAVESPQFGK--------------AGG
MUL_0391|M.ulcerans_Agy99 -----------IGGDGVIGGDGQAGSAGEFPGD--------------RGG
Mb1121|M.bovis_AF2122/97 -----NARLWGVGGAGGAGGDGGAGGAGGKGGSGLS--------GNANGG
Rv1091|M.tuberculosis_H37Rv -----NARLWGVGGAGGAGGDGGAGGAGGKGGSGLS--------GNANGG
Mflv_5091|M.gilvum_PYR-GCK -----------AGATGGKGGNGGNGGRGGLFG---------------KGG
Mvan_1264|M.vanbaalenii_PYR-1 -----------AGATGGKGGNGGNGGRGSLFG---------------RGG
MSMEG_0868|M.smegmatis_MC2_155 GNTAIGGNGGAASANGAVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGG
TH_3810|M.thermoresistible__bu -----------SSGTHPMAEDGE--HVKALDGR--------------PGL
MAB_4284c|M.abscessus_ATCC_199 -----------LAGNAGLAGNAGLAGNAGLAGN------------AGLAG
MAV_4827|M.avium_104 ---------IRTTGTVALQPTPNQHLIVPTEQAP------------APPP
MLBr_01556|M.leprae_Br4923 ---------PPVVTVMGHVDHGKTRLLDTIRKANVR-----------EAE
MMAR_5038|M.marinum_M PGGDGGR----------------------GGLGGFGGDGGAGGHALAPRY
MUL_0391|M.ulcerans_Agy99 SGGAGAR----------------------GGNGGDGGAGGAGGHALAEGF
Mb1121|M.bovis_AF2122/97 AGGDSGR----------------------GGTGGAGGEGGAAGLLVGTGG
Rv1091|M.tuberculosis_H37Rv AGGDSGR----------------------GGTGGAGGEGGAAGLLVGTGG
Mflv_5091|M.gilvum_PYR-GCK NAGNGAD----------------------GGTGGAGGAGGTGG-TGGAGG
Mvan_1264|M.vanbaalenii_PYR-1 NAGNGGN----------------------GGTGGNGGNGGTGG-TGGNGG
MSMEG_0868|M.smegmatis_MC2_155 NGGNGGNGWVQAYDPNGPAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGG
TH_3810|M.thermoresistible__bu DGGNGSH----------------------GGNGGHGGRGGFLG-------
MAB_4284c|M.abscessus_ATCC_199 NAGLAGN----------------------AGLAGNAGLAGNAGLAGNAGL
MAV_4827|M.avium_104 VQASAPQ----------------------PKISVPEPVAAPKPLSPPVAA
MLBr_01556|M.leprae_Br4923 AGGITQH---------------------IGAYQVGVDLDGSERLITFIDT
. .
MMAR_5038|M.marinum_M HDG-----------------APGAG------------------GVGGDGG
MUL_0391|M.ulcerans_Agy99 HDG-----------------AAGTG------------------GMGGDG-
Mb1121|M.bovis_AF2122/97 HGG-----------------DGGAGGAAVKGGDGGAAAGTGIAGAGGRGG
Rv1091|M.tuberculosis_H37Rv HGG-----------------DGGAGGAAVKGGDGGAAAGTGIAGAGGRGG
Mflv_5091|M.gilvum_PYR-GCK TGG-----------------TGGTGGIGGAGSTGGTGGTGGTGGTGGTGG
Mvan_1264|M.vanbaalenii_PYR-1 TGG-----------------TGGTGGIGGAGSTGGTGGTGGTGGTGGTGG
MSMEG_0868|M.smegmatis_MC2_155 DGAGASVWKANGQHSTGQTDTGGNGGRGGDGGTFVNAGANGNGGAGGAGG
TH_3810|M.thermoresistible__bu --------------------------------------------IGGSGG
MAB_4284c|M.abscessus_ATCC_199 AGN---------------------------------------AGLAGNAG
MAV_4827|M.avium_104 PLP--------------------------------------AAPPPAAPP
MLBr_01556|M.leprae_Br4923 PGH------------------EAFTAMRARGAKATDIAILVVAADDGVMP
.
MMAR_5038|M.marinum_M AG-GNGGRGGDGANGVNAAT-----------------------LASVIG-
MUL_0391|M.ulcerans_Agy99 ---GNGADGGDGHSGDP---------------------------SWRSG-
Mb1121|M.bovis_AF2122/97 AG-GSGGSGGDGGGGAAGPAGWLFGDGGAGGNGGAAAAGGAGGQAGGGG-
Rv1091|M.tuberculosis_H37Rv AG-GSGGSGGDGGGGAAGPAGWLFGDGGAGGNGGAAAAGGAGGQAGGGG-
Mflv_5091|M.gilvum_PYR-GCK TG-GTGGTGGTGGTGGKGGTGGTGGAGGTG----GDGGTGGTGGTGGTG-
Mvan_1264|M.vanbaalenii_PYR-1 TG-GTGGTGGTGGTGGKGGTGGTGGDGGTG----GTGGTGGTGGTGGTG-
MSMEG_0868|M.smegmatis_MC2_155 VSEGEGGTGGHGGDGGRGGDGALGGNGGTGGVGLGNGGKGGNGGNGGNGG
TH_3810|M.thermoresistible__bu WG-GHGGNGGD---------------------------------TDADG-
MAB_4284c|M.abscessus_ATCC_199 LAGNAAVAGNAAVAGNAAVAG----------------------NAAVGG-
MAV_4827|M.avium_104 LPEAPPIPAAPPVVPVPVVVPPVPVPVPVRIPVPDPVSPPQLLAPPRLSV
MLBr_01556|M.leprae_Br4923 QTVEAINHAQAADVPIVVAVNKIDKEGADPAKIRGQLTEYGLVAEDFGG-
. .
MMAR_5038|M.marinum_M --------GNGGDGGNGGYG---------------NLGGY----------
MUL_0391|M.ulcerans_Agy99 --------GDGGNGGNGAYG---------------GSGGQ----------
Mb1121|M.bovis_AF2122/97 --------GNGGNGGNGGNG---------------GNGGNGATGGWLYGN
Rv1091|M.tuberculosis_H37Rv --------GNGGNGGNGGNG---------------GNGGNGATGGWLYGN
Mflv_5091|M.gilvum_PYR-GCK --------GTGGTGGTGGAG-----------DGTGGTGGTGG----TGGQ
Mvan_1264|M.vanbaalenii_PYR-1 --------GTGGTGGTGGAG-----------DGLGGTGGTGG----TGGF
MSMEG_0868|M.smegmatis_MC2_155 TYVDPSHTGAGGNGGNGGAGRIRVNNGTATGTATGGNGGNGGNGDADGHR
TH_3810|M.thermoresistible__bu --------GNGGDGGNGGSA---------------GRGGT----------
MAB_4284c|M.abscessus_ATCC_199 ------VLNTGVSGAIGGSS---------------HVGGAIN--------
MAV_4827|M.avium_104 P----QPVQPPVRVPQPPSP--------------PQVGGTVPQSPPQHQT
MLBr_01556|M.leprae_Br4923 ---DTMFIDISAKVGTNIEALLEAVLLTADAALDLRANSGMEAQGVAIEA
..
MMAR_5038|M.marinum_M GGLSGDGS-----------------TRAGQGVAG----------------
MUL_0391|M.ulcerans_Agy99 GGLNGDGA-----------------TRAAHGVQG----------------
Mb1121|M.bovis_AF2122/97 GGAGGQGA-----------------TAGAGGAGANGVSSTNGG-------
Rv1091|M.tuberculosis_H37Rv GGAGGQGA-----------------TAGAGGAGANGVSSTNGGG------
Mflv_5091|M.gilvum_PYR-GCK GGQGGQGG-----------------TGGTGGQGG-LGGGGGTG-------
Mvan_1264|M.vanbaalenii_PYR-1 GGQGGQGG-----------------TGGTGGQGG-LGGVGGTG-------
MSMEG_0868|M.smegmatis_MC2_155 GGKGGDGGEALIRATVIGSNASGTATGGDGGNGGTLGATNGTGGAATIVA
TH_3810|M.thermoresistible__bu GGLRGVFG-----------------INGGNGRAG----------------
MAB_4284c|M.abscessus_ATCC_199 ESLGGSGS-----------------VGGSTAVGG----------------
MAV_4827|M.avium_104 PPGEGTPP-----------------KPDGPGNYG----------------
MLBr_01556|M.leprae_Br4923 HLDRGRGP-----------------VATVLVQRG----------------
* .
MMAR_5038|M.marinum_M --------------------IDGDGGDGGNGGNG----------------
MUL_0391|M.ulcerans_Agy99 --------------------TMGDGGDGGDGGNG----------------
Mb1121|M.bovis_AF2122/97 ----------------GNGGIGGTGGSGGAGGNAGL-----------LGV
Rv1091|M.tuberculosis_H37Rv --------------TGGNGGIGGTGGSGGAGGNAGL-----------LGV
Mflv_5091|M.gilvum_PYR-GCK ----------------GQGGTGGTGGQGGTGGTGGTGGTG--------GT
Mvan_1264|M.vanbaalenii_PYR-1 ----------------GTGGTGGTGGQGGTGGTGGTGGTG--------GT
MSMEG_0868|M.smegmatis_MC2_155 YNVVQANPQASGTATDGHGGSGINGGHGGNGGQGTIEANGPSAVASGIGA
TH_3810|M.thermoresistible__bu --------------------LGGRGXXXXGGGVG---------------A
MAB_4284c|M.abscessus_ATCC_199 ---------------------GAHTGVGGGVSTG-------------VGV
MAV_4827|M.avium_104 ---------------------GGHVPTPGAGGSG----------------
MLBr_01556|M.leprae_Br4923 -----------------TLRIGDSVVAGDAYGRVRRMVDEHG---VDIEA
.
MMAR_5038|M.marinum_M STTDHGVIPQGWGGNGGNGGRGFN------GGDGG--DGGNG--------
MUL_0391|M.ulcerans_Agy99 STTSDQVDID--GGNGGYGGWGFN------GGNGG--NGGDG--------
Mb1121|M.bovis_AF2122/97 GGAGGHGASGGAGDRGGAGGTGFISSDGGAGGDGG--DGGNG--------
Rv1091|M.tuberculosis_H37Rv GGAGGHGASGGAGDRGGAGGTGFISSDGGAGGDGG--DGGNG--------
Mflv_5091|M.gilvum_PYR-GCK GGAGGDGGLGGLGGFGGSGGTGGQGGLGGPGGSTGGAGGAGG--QAGTAG
Mvan_1264|M.vanbaalenii_PYR-1 GGAGGDGGLGGLGGFGGVGGTGGQGGQGGPGGSTGGAGGAGG--QAGVAG
MSMEG_0868|M.smegmatis_MC2_155 GGNGGDGIDGGLGGNGGDGVVNTTANAANPGSATGTATGGDGGKATGTAS
TH_3810|M.thermoresistible__bu AVRSGNGVFSGGGGTPSAGFGVPTTIQFPAGSCTSRAVSREG--------
MAB_4284c|M.abscessus_ATCC_199 GSHVGGGISESLGGSGSVGGSTAVGGGAHTGVGGGVSTGVG---------
MAV_4827|M.avium_104 GSGGGHVPTPGAGGSGGSGGGHVPTPGTGGPGGTGGSGGGHVP-------
MLBr_01556|M.leprae_Br4923 ALPSSPVQVIGFTSVPGAGDNFLVVDEDRIARQIADRRSARKR-------
. . . * . .
MMAR_5038|M.marinum_M ------------------GSGPTTLRLFGRVG------------------
MUL_0391|M.ulcerans_Agy99 ------------------GTRPKGT-LFFRSG------------------
Mb1121|M.bovis_AF2122/97 ------------------GAGGTGGLLFGAGGNGGPGGSGGAADIGGNGG
Rv1091|M.tuberculosis_H37Rv ------------------GAGGTGGLLFGAGGNGGPGGSGGAADIGGNGG
Mflv_5091|M.gilvum_PYR-GCK KGGLFG----GSGSAGKAGATGAAGASGGKGAQGATGAQGATG------A
Mvan_1264|M.vanbaalenii_PYR-1 KGGLFG----GSGSAGTAGVTGASGASGGKGAQGATGAQGATG------A
MSMEG_0868|M.smegmatis_MC2_155 QGGNGGPSWVQSGYGSTLGGNATGTATAGKGGEASNGGVAGNGGNALVMA
TH_3810|M.thermoresistible__bu -------------------IMPSSRAASARAG------------------
MAB_4284c|M.abscessus_ATCC_199 -----------------VGSHVGGGISESLGGSGSVGGSTAVG-------
MAV_4827|M.avium_104 --------------------TPGAGTPGGSGG------------------
MLBr_01556|M.leprae_Br4923 NALAARSRKRISLEDLDSALKETSQLNLILKGDNAGTVEALEEALMGIQV
.
MMAR_5038|M.marinum_M --------GDGGDGGRGGDA------------------------------
MUL_0391|M.ulcerans_Agy99 --------GDGGFGGWGGNG------------------------------
Mb1121|M.bovis_AF2122/97 AGNGGGTDGNGGNGGSGGGAGSGGDGGGAGG-----------------NG
Rv1091|M.tuberculosis_H37Rv AGNGGGTDGNGGNGGSGGGAGSGGDGGGAGG-----------------NG
Mflv_5091|M.gilvum_PYR-GCK QGATG-ATGAAGKAGATGAAGAAGAAGSAG-----------TTGAQGSAG
Mvan_1264|M.vanbaalenii_PYR-1 QGATG-ATGASGAQGSAGSAGSAGVAGSAG-----------TTGAQGSAG
MSMEG_0868|M.smegmatis_MC2_155 AGTTGVATGNTATGGDGGAATTAGATGGAGGFSNIAAIHGAITDSTAISG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------GGAHTGVGGGVNTGVGVGSHVGG-------------------
MAV_4827|M.avium_104 --------GHLPFPGAGSTP------------------------------
MLBr_01556|M.leprae_Br4923 DDEVALRVIDRGVGGITETNVNLASASDAIIIG-----------------
MMAR_5038|M.marinum_M -----YGGNAGWGGDGGNGGRGAYGSGLI-PPARGGDGGNGGDGGDLYIN
MUL_0391|M.ulcerans_Agy99 -----YGGVG---------------------------GGNGGAGGTAYTS
Mb1121|M.bovis_AF2122/97 AWLFGNGGAGGGGGKGGNGAGGGLGGGSFGLPGLNGSGGDGGDGGNGAPG
Rv1091|M.tuberculosis_H37Rv AWLFGNGGAGGGGGKGGNGAGGGLGGGSFGLPGLNGSGGDGGDGGNGAPG
Mflv_5091|M.gilvum_PYR-GCK TNGA-NGANGSQGAAGKAGATGTTGATG--------AAGEDGDAGSGGSG
Mvan_1264|M.vanbaalenii_PYR-1 TNGA-NGANGSQGAAGKAGATGTTGATG--------AAGDAGDPGSEAVD
MSMEG_0868|M.smegmatis_MC2_155 HGGAGNGGNGGKGADGWVQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTG
TH_3810|M.thermoresistible__bu ----------------------------------------AACASSTSRS
MAB_4284c|M.abscessus_ATCC_199 ------GISESLGGSGSVGGSTAVGGGAHTSAINDALGGSGSVGGSTAVG
MAV_4827|M.avium_104 ---------------------------------------GGSGGGHLPTP
MLBr_01556|M.leprae_Br4923 ------FNVRAEGKATELASREGVEIRYYLVIYQAIDDIEKALRGMLKPI
. .
MMAR_5038|M.marinum_M GVMYQHGGAGFDGL-----PGEPPDIPPIGGLGGKGGSGG----------
MUL_0391|M.ulcerans_Agy99 GGVYAGG-PVQPGT-----EGTGP-SGDHGGFGGSGGIGG----------
Mb1121|M.bovis_AF2122/97 GVLYGNGGAGGQGS-----SGGIGGPGATGGAGGKGGDGGDAQLIGDGGN
Rv1091|M.tuberculosis_H37Rv GVLYGNGGAGGQGS-----SGGIGGPGATGGAGGKGGDGGDAQLIGDGGN
Mflv_5091|M.gilvum_PYR-GCK -INGGAGGAGG-----------AGGEGGEGGDGGKGGAGAE--------G
Mvan_1264|M.vanbaalenii_PYR-1 -INGGAGGAGG-----------AGGEGGEGGAGGAGGDGSE--------G
MSMEG_0868|M.smegmatis_MC2_155 GASGGDGGNGGNTSVWKSGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAG
TH_3810|M.thermoresistible__bu RRSFCCSRA-----------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GGAHTSAINESMNS----SINASHSSSMNESFGSSMGSHG----------
MAV_4827|M.avium_104 GAGTPGGGLGGFGG--------GHAPAPGGGLGGGGGHAP----------
MLBr_01556|M.leprae_Br4923 YEENQLGRAEIRALFRSSKVGIIAGCIISSGVVRRNAKVRLLRDNIVVTD
.
MMAR_5038|M.marinum_M ------------LGPHAP-------------------------------
MUL_0391|M.ulcerans_Agy99 ------------HGGQAP-------------------------------
Mb1121|M.bovis_AF2122/97 GGNGGAGGTGGTPGPGGPGGSGGLGG--LLFGQTGTAGVSP--------
Rv1091|M.tuberculosis_H37Rv GGNGGAGGTGGTPGPGGPGGSGGLGG--LLFGQTGTAGVSP--------
Mflv_5091|M.gilvum_PYR-GCK GAGGGGGAGGSGAGGAG--GAGGSGGSGGSGGSGGSGGAAGDSDD----
Mvan_1264|M.vanbaalenii_PYR-1 GAGGSGGAGGSGTGGAG--GAGGSGGSGGSGGAGGSGGAAGDSD-----
MSMEG_0868|M.smegmatis_MC2_155 GAGGNGGTGGTTAGGSGNGGNGGNGGNGGADGTPGTAGTTGANNP----
TH_3810|M.thermoresistible__bu -------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------AAGTGFEAQGHAQGHASETAHTTLPGAEHH-------
MAV_4827|M.avium_104 ------------APGGGLGGFGGGHSGGGLGGLGGGHK-----------
MLBr_01556|M.leprae_Br4923 NLTVTSLRREKDDVTEVREGFECGMTLGYSDIKEGDVIESYELVEKQRA