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MHLDEYMSLDATGLAELVATKQVRATELLALARQRADAVNPRLNAIIRRIDALAEGRAADPELRGPLAGV PFLIKDLDQEYRGFPSSCGSRSLANDVAKQHALVTQRFLDAGLVVFGMTNTPEFGAKGITEPDYWGPARN PWNPQHTPGGSSGGSGAAVAAGIVPLAGANDGGGSIRIPAACNGLVGLKLSRGLSPYGPQTGEPLFGMET QGVVSRTVRDSAASYDAIVGPNPRAAYQVALPDTTFVEHIKKRPGALKIGYSASSAINAAPDREAVAAVE AAASLLEDLGHRVEQVDPPYDDAALARDFLTIWFAQLHSQVAEIRKRIGARDSDFEADTLAMAELGRSTG VLAPLLALDNRNNYIQSLASFHESYDYFLTPSLATPPLAVGDTTTSPRLQTAARLLSKLRAGKVLSLSGI MDDLIQESLGWVPYTQLANLTGRPAISVPLHWTPAGLPLGVQFVGGLGSDGDLLALAAQLEEARPWAQRH PATPPAG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4954 | amiC_2 | - | 100% (497) | amidase, AmiC_2 |
| M. marinum M | MMAR_3565 | amiC_1 | 1e-84 | 40.41% (490) | amidase AmiC_1 |
| M. marinum M | MMAR_1821 | amiC | 2e-64 | 36.44% (494) | amidase AmiC |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2912c | amiC | 4e-65 | 36.86% (491) | amidase |
| M. gilvum PYR-GCK | Mflv_1016 | - | 1e-153 | 58.08% (489) | amidase |
| M. tuberculosis H37Rv | Rv2888c | amiC | 4e-65 | 36.86% (491) | amidase |
| M. leprae Br4923 | MLBr_01596 | - | 2e-61 | 34.70% (487) | amidase |
| M. abscessus ATCC 19977 | MAB_2181c | - | 1e-144 | 53.59% (487) | putative amidase |
| M. avium 104 | MAV_0676 | - | 0.0 | 77.60% (491) | 6-aminohexanoate-cyclic-dimer hydrolase |
| M. smegmatis MC2 155 | MSMEG_6673 | - | 1e-150 | 55.71% (490) | 6-aminohexanoate-cyclic-dimer hydrolase |
| M. thermoresistible (build 8) | TH_2520 | - | 9e-64 | 34.62% (491) | PUTATIVE Amidase |
| M. ulcerans Agy99 | MUL_0540 | amiC_2 | 0.0 | 98.59% (497) | amidase, AmiC_2 |
| M. vanbaalenii PYR-1 | Mvan_5822 | - | 1e-150 | 56.58% (486) | amidase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4954|M.marinum_M ------MHLDEYMSLDATGLAELVATKQVRATELLALARQRADAVNPRLN
MUL_0540|M.ulcerans_Agy99 ------MHLDEYMSLDATGLAELVATKQVRATELLALARQRADAVNPRLN
MAV_0676|M.avium_104 ------------MALDATALAGLVADKQVTPAELLALARQRADAVNPRLN
MSMEG_6673|M.smegmatis_MC2_155 ------MNFDEYRTFDATGLAELVADKQVTAAELLEVAQARAEAVNPRIN
Mvan_5822|M.vanbaalenii_PYR-1 -----MVDFQEYRAQDATGLARLVAEKQVTADELLALAQARAAQVNPRIN
Mflv_1016|M.gilvum_PYR-GCK ------MDFLEYRSHDATGLAKLVADGDVTADELLTLARERAAAVNPKIN
MAB_2181c|M.abscessus_ATCC_199 ------MDFSDYSQHDATGLAELVATKQVTPAELLAAARARAADVNNKIG
Mb2912c|M.bovis_AF2122/97 MSRVHAFVDDALGDLDAVALADAIRSGRVGRADVVEAAIARAEAVNPALN
Rv2888c|M.tuberculosis_H37Rv MSRVHAFVDDALGDLDAVALADAIRSGRVGRADVVEAAIARAEAVNPALN
MLBr_01596|M.leprae_Br4923 MQRVHAFGDDALGDLDAVGLADAIRAGWVSRADVIEAAIVRTEAVNPALG
TH_2520|M.thermoresistible__bu MQRIHAFGDDALSDLDAVGLAAELRARRVSVPELIRAAIARTEAVNPALN
**..** : * ::: * *: ** :.
MMAR_4954|M.marinum_M AIIRRIDALAEGRAADPE-LRGPLAGVPFLIKDLDQEYRGFPSSCGSRSL
MUL_0540|M.ulcerans_Agy99 AIIRRIDALAEGRAADPE-LRGPLAGVPFLIKDLDQEYRGFSSSCGSRSL
MAV_0676|M.avium_104 AIVCRLDDVADRQAADPN-LSGPFAGVPFLLKDLGQEYRGFPTSCGSRSL
MSMEG_6673|M.smegmatis_MC2_155 AIVREVPAAPADAA------PGPFTGVPFLIKDIGQDYAGVPSSRGSRAL
Mvan_5822|M.vanbaalenii_PYR-1 AIVRDVPAAPAGIA------DGPFAGVPFLIKDLAQDYAGLPSSRGSRAL
Mflv_1016|M.gilvum_PYR-GCK AIVRDVPAPVGGNR------GGPFAGVPFLIKDLAQDYAGLPTASGSRSL
MAB_2181c|M.abscessus_ATCC_199 AIVRTLPEADQQVQGD---LTGPFAGVPFLIKDLGQDYKGHPTSGGCRAL
Mb2912c|M.bovis_AF2122/97 ALAYAAFDVARDAAAMGTGQEAFFSGVPTFIKDN-VDVAGQPSMHGTDAW
Rv2888c|M.tuberculosis_H37Rv ALAYAAFDVARDAAAMGTGQEAFFSGVPTFIKDN-VDVAGQPSMHGTDAW
MLBr_01596|M.leprae_Br4923 GLAYEAFQWARQTASKAG--SGFFSGVPTFIKDN-IDVAGQPTMRGSDAW
TH_2520|M.thermoresistible__bu GLAYEAFDRALARAEAGP-VPGFFGGIPTYVKDN-AAVAGMPTMEGTDAW
.: . : *:* :** * .: * :
MMAR_4954|M.marinum_M ANDVAKQHALVTQRFLDAGLVVFGMTNTPEFGAKGITEPDYWGPARNPWN
MUL_0540|M.ulcerans_Agy99 ANDVAKQHALVTQRFLDAGLVVFGMTNTPEFGAKGITEPDYWGPARNPWN
MAV_0676|M.avium_104 ANDVADRHALVTQRFLDAGLVIFGKTNTPEFGAKGVTEPDYWGPARNPWD
MSMEG_6673|M.smegmatis_MC2_155 RSIPVTEHATVVQRWIEAGLVIFGKTNTPEFGAKGITEPEAWGPTRNPWN
Mvan_5822|M.vanbaalenii_PYR-1 MSLPAAEHSTIVQRWIDAGVVIFGKTNTPEFGAKGITEPVAWGPTRNPWD
Mflv_1016|M.gilvum_PYR-GCK MSRPAGEHATVVQRWLDAGLVIFGKTNTPEFGAKGITEPQAYGPARNPWD
MAB_2181c|M.abscessus_ATCC_199 STLPAPEHSTIVRRWLDAGLVIFGKTNTPEFGSKGITEPELFGASRNPWD
Mb2912c|M.bovis_AF2122/97 EPYAAVADSEITRVVLGTGLVSLGKTQLSEFGFSAVAEHPRLGPVRNPWN
Rv2888c|M.tuberculosis_H37Rv EPYAAVADSEITRVVLGTGLVSLGKTQLSEFGFSAVAEHPRLGPVRNPWN
MLBr_01596|M.leprae_Br4923 VPRNAFDDGEFTRLYLATGPVSLGKTQLSEFGFSASAEHMRLGPVRNPWD
TH_2520|M.thermoresistible__bu DPRPQPAHGDFARLYLGTGVIPLGKTQMSEFGFSASAEHPRLGPVRNPWH
.. ..: : :* : :* *: .*** .. :* *. ****.
MMAR_4954|M.marinum_M PQHTPGGSSGGSGAAVAAGIVPLAGANDGGGSIRIPAACNGLVGLKLSRG
MUL_0540|M.ulcerans_Agy99 PQHTPGGSSGGSGAAVAAGIVPLAGANDGGGSIRIPAACNGLVGLKLSRG
MAV_0676|M.avium_104 TERTPGGSSGGSGAAVAAGIVPAAGANDGGGSIRIPAACNGLVGLKPSRG
MSMEG_6673|M.smegmatis_MC2_155 LTHTPGGSSGGSAAAVAAGIVPCAGANDGGGSIRIPAACCGLVGLKPGRG
Mvan_5822|M.vanbaalenii_PYR-1 VTRTPGGSSGGSAAAVAAGIVPCAGANDGGGSIRIPAACCGLVGLKPGRG
Mflv_1016|M.gilvum_PYR-GCK LTRSPGGSSGGSAAAVAAGITPCAGASDGGGSIRIPAACCGLVGLKPGRG
MAB_2181c|M.abscessus_ATCC_199 LGRTPGGSSGGSAAAVAAGIVPVAGASDGGGSIRIPAGCCGLVGLKPGRG
Mb2912c|M.bovis_AF2122/97 TDYTAGASSSGSGALVAAGVVPIAHANDGGGSIRIPAACNGLVGLKPSRG
Rv2888c|M.tuberculosis_H37Rv TDYTAGASSSGSGALVAAGVVPIAHANDGGGSIRIPAACNGLVGLKPSRG
MLBr_01596|M.leprae_Br4923 TDYTAGASSSGSGAFVAAGVVPMAHANDGGGSIRIPASCNGLVGLKPSRG
TH_2520|M.thermoresistible__bu PEHTAGASSSGSGAFVAAGVVPIAHANDGGGSIRIPAACNGLVGLKPSRG
:.*.**.**.* ****:.* * *.**********.* ****** .**
MMAR_4954|M.marinum_M LSPYGPQTGEPLFGMETQGVVSRTVRDSAASYDAIVGPNPRAAYQVALPD
MUL_0540|M.ulcerans_Agy99 LSPYGPQTGEPLFGMETQGVVSRTVRDSAAIYDAIVGPNPRAAYQVALPD
MAV_0676|M.avium_104 LAPYGPQTGELMLGMATQGVVTRTVRDSAALLDAIIGHHPDASYRVALPD
MSMEG_6673|M.smegmatis_MC2_155 LTPMGPALSESVHGATVQGVVSRTVRDTAAMLDVISGGEPSGPYAPKLPG
Mvan_5822|M.vanbaalenii_PYR-1 LTPMGPELGESMHGSAVQGVVSRTVRDTAAMLDVISGGEPWGPFTPGMPN
Mflv_1016|M.gilvum_PYR-GCK LTPSGPASGEAMHGAAVQGVVTRTVRDSAAMLDVISGGEPYGPFVPALPE
MAB_2181c|M.abscessus_ATCC_199 ITPMGPTAGEPMHGAAVNGTVSRTVRDTASMLDIIAGPEPTSPYLSAMPQ
Mb2912c|M.bovis_AF2122/97 RLPLEPEYRRLPVGIVANGVLTRTVRDTAAFYREAERLWRN----HQLP-
Rv2888c|M.tuberculosis_H37Rv RLPLEPEYRRLPVGIVANGVLTRTVRDTAAFYREAERLWRN----HQLP-
MLBr_01596|M.leprae_Br4923 RLPLDSELRRLPVGIVVNGVLTRSVRDTAAFYREAERIWHN----PKLP-
TH_2520|M.thermoresistible__bu RLPLDRHMRQMPLRIVANGVLTRSVRDTAAFYREAELLTGR----TRLP-
* . .:*.::*:***:*: :*
MMAR_4954|M.marinum_M TTFVEHIKKRPGALKIGYSASSAINAAPDREAVAAVEAAASLLEDLGHRV
MUL_0540|M.ulcerans_Agy99 TTFVEHIKNRPGALKIGYSASSAINAAPDREAVAAVEAAASLLEDLGHRV
MAV_0676|M.avium_104 KPFAQQITRPPGPLTIGYSARSALNPRPDREAVAAVENSAALLSALGHRV
MSMEG_6673|M.smegmatis_MC2_155 TPFASAVGADPGKLRIGVRVPSAINPNPHREAYAAVEATAQTLTELGHHV
Mvan_5822|M.vanbaalenii_PYR-1 APFASCVGQDPGRLRIGVRVPTAITPVPHREAFAAVEATVQTLTDLGHHV
Mflv_1016|M.gilvum_PYR-GCK ASFASCVGTDPGTLRIGVRVPSAITPQPHREAFAAVEATTRLLTDLGHEV
MAB_2181c|M.abscessus_ATCC_199 DSYASQVGRDPGRLRIGVRVPTVITPNPDPAAVAAVETAIRLLTHLGHEV
Mb2912c|M.bovis_AF2122/97 -PVGDVTSPVKQRLRIAVVTRSVLR-EASPEVRQLTLKLAGLLEELGHRV
Rv2888c|M.tuberculosis_H37Rv -PVGDVTSPVKQRLRIAVVTRSVLR-EASPEVRQLTLKLAGLLEELGHRV
MLBr_01596|M.leprae_Br4923 -PVGDVTQPGRQRLRIAVVTRSVQR-ECSPELRELTLKSARLLEELGHRV
TH_2520|M.thermoresistible__bu -PIGDITRPGAERLRIAVCTRSINR-DASPEVRELTLKTAALLEELGHHV
. . * *. . : . * ***.*
MMAR_4954|M.marinum_M EQVD-PPYDDAALARDFLTIWFAQLHSQVAEIRKRIGARDSDFEADTLAM
MUL_0540|M.ulcerans_Agy99 EQVD-PPYDDAALARDFLTIWFAQLHSQVAEIRKRIGARNSDFEADTLAM
MAV_0676|M.avium_104 REVA-PPYDDAALGRDFLTIWFAQLHQQVADIRRRTGARDNDFEADTLAI
MSMEG_6673|M.smegmatis_MC2_155 EELPQAPFDDAALAREFLLSWFVYTAWELEEAKRISGAGDEAFERDTLIL
Mvan_5822|M.vanbaalenii_PYR-1 DELPQAPFDDAALAREFLLTWFVYTAWELADAKRLTGAGDDAFERDTLIL
Mflv_1016|M.gilvum_PYR-GCK TELAEAPYDDAVLARDFLLTWFVTLAWEVAEAKRLTGAGDDQFETDTLVM
MAB_2181c|M.abscessus_ATCC_199 EEVS-APYDDGQLARDFLLTWFVHAAYEVDYTKRLTGAGDEGFERDTLLI
Mb2912c|M.bovis_AF2122/97 EHVDHPPAPAS-FVDDFVLYWGFLALAQVRSGRRTFGRTFDPTRLDELTL
Rv2888c|M.tuberculosis_H37Rv EHVDHPPAPAS-FVDDFVLYWGFLALAQVRSGRRTFGRTFDPTRLDELTL
MLBr_01596|M.leprae_Br4923 ERVAEPPVPPN-FPDDFLLYWGLLAAMQVRTGRLAFGNTFDRTKLDSLTL
TH_2520|M.thermoresistible__bu TPIDN-PVPRQ-FQDDFLLYWAFLAMAVVRSGRRTFGPGFDRDRLDNLTL
: * : :*: * : : * . . * * :
MMAR_4954|M.marinum_M AELGRSTGVLAPLLALDNRNNYIQS-LASFHESYDYFLTPSLATPPLAVG
MUL_0540|M.ulcerans_Agy99 AELGRSTGVLAPLLALDNRNNYIQS-LASFHESYDYFLTPSLATPPLTVG
MAV_0676|M.avium_104 SELGRSGGVLPVMSALENRNTYIQS-LAAFHEGYDFFLTPTLATPPLVVG
MSMEG_6673|M.smegmatis_MC2_155 AAIGRATSSVAYVDAVQRRHDHTRR-LTTFFESYDLLMTPTLATPPPRIG
Mvan_5822|M.vanbaalenii_PYR-1 AAIGRATSSVDYLDAVQRRHDHTRR-LTRFFDSYDLLLTPSLATPPPAIG
Mflv_1016|M.gilvum_PYR-GCK AALGRATSSVDYVDAVQRRHEHTRR-LTRFFESYDLLLTPTLATPPPRIG
MAB_2181c|M.abscessus_ATCC_199 AALGRTTSGPEYVAAVERRHDYVRE-LATFFGDYDLLLTPTLAKAPPRIG
Mb2912c|M.bovis_AF2122/97 GLARHTGRNLHRLPLAIMRLRMLRRRSVRFFGTYDVLLTPTVAEATPQVG
Rv2888c|M.tuberculosis_H37Rv GLARHTGRNLHRLPLAIMRLRMLRRRSVRFFGTYDVLLTPTVAEATPQVG
MLBr_01596|M.leprae_Br4923 GLDRHASRNMHRLPKAIMRLRRLRRRTADFFATYDVLLTPTVADETPRIG
TH_2520|M.thermoresistible__bu GLDSHAARNLHRLPAAMVRLSRLRRVTARLTRDFDVVLTPTLADVPPRIG
. :: : * : . : :* .:**::* . :*
MMAR_4954|M.marinum_M DTTTSPRLQTAARLLSKLRAGKVLSLSGIMDDLIQESLGWVPYTQLANLT
MUL_0540|M.ulcerans_Agy99 DTTTSPRLQTAARLLSKLRAGKVLSLSGIMDDLIQESLGWVPYTQLANLT
MAV_0676|M.avium_104 ATSTSAALQRAARLVSRVRGGKLMRLSGILDDLIRESLGWVPYTQLANLT
MSMEG_6673|M.smegmatis_MC2_155 EFELPELLKRGSDVLLKTRTAGLLRFTKILDDSVDANLAWVPYTQLANIT
Mvan_5822|M.vanbaalenii_PYR-1 EFDLPVALQKASDVLLKTRTAHLLRFTKIVDDIVDKNLGWVPYTQLANIT
Mflv_1016|M.gilvum_PYR-GCK EFDMPAVMQRAADVLLKTRTARLLRHTGIVDDMVDQNLGWVPYTQLANIT
MAB_2181c|M.abscessus_ATCC_199 EFNLPAPLAAVSDLLLRTKTARVLKYANIVDSMINDNLGWVPYTQLANLT
Mb2912c|M.bovis_AF2122/97 YLAPT-DYQTVLDRLS----------------------SWVVFTPVQNVT
Rv2888c|M.tuberculosis_H37Rv YLAPT-DYQTVLDRLS----------------------SWVVFTPVQNVT
MLBr_01596|M.leprae_Br4923 YLTPT-DYQQVMDRLM----------------------GWVAFTPLQNVT
TH_2520|M.thermoresistible__bu HLDPTADYQQIIDRLV----------------------DWVAFTPLHNVT
. : ** :* : *:*
MMAR_4954|M.marinum_M GRPAISVPLHWTPAGLPLGVQFVGGLGSDGDLLALAAQLEEARPWAQRHP
MUL_0540|M.ulcerans_Agy99 GRPAISLPLHWTPAGLPLGVQFVGGLGSDGDLLALAAQLEEARPWAHRHP
MAV_0676|M.avium_104 GRPAISVPLHWTDDGLPLGVQFVGKLGADGDLLQLAAQLEQARPWAQRHP
MSMEG_6673|M.smegmatis_MC2_155 GRPAVTLPLHWTADGLPLGVQFVAPLEGESLLIRLGAQLEEAMPWKDRVA
Mvan_5822|M.vanbaalenii_PYR-1 GRPAISLPLHWTEEGLPLGVQFVAPLGGESLLVRLAAQLEQAMPWRDRVA
Mflv_1016|M.gilvum_PYR-GCK GRPAISLPLHWTADGLPLGVQFVAPLAGEALLLRLAGQLEQAAPWAHRTA
MAB_2181c|M.abscessus_ATCC_199 GRPAISLPLYQTPKGLPLGVQFVAPLGGESLLIRLAAQLEATEPWAHRRP
Mb2912c|M.bovis_AF2122/97 GVPAISLPLAQSADGMPVGMMLSADTGREALLLELAYELEEARPWARIHA
Rv2888c|M.tuberculosis_H37Rv GVPAISLPLAQSADGMPVGMMLSADTGREALLLELAYELEEARPWARIHA
MLBr_01596|M.leprae_Br4923 GEPAISLPLAQSADGMPVGMMFTADFGQEAQLLELAFELEEARPWARIQI
TH_2520|M.thermoresistible__bu GEPAVSLPLAQSRDGLPVGMMFAAALGEEARLLRLAYELEEARPWPRIDQ
* **:::** : *:*:*: : . :. *: *. :** : **
MMAR_4954|M.marinum_M A--TPPAG
MUL_0540|M.ulcerans_Agy99 A--TPPAG
MAV_0676|M.avium_104 APVTPPN-
MSMEG_6673|M.smegmatis_MC2_155 PV------
Mvan_5822|M.vanbaalenii_PYR-1 PV------
Mflv_1016|M.gilvum_PYR-GCK AL------
MAB_2181c|M.abscessus_ATCC_199 TL------
Mb2912c|M.bovis_AF2122/97 PNIAE---
Rv2888c|M.tuberculosis_H37Rv PNIAE---
MLBr_01596|M.leprae_Br4923 GD------
TH_2520|M.thermoresistible__bu RS------