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KISLFYEFALPRPWAPDDERIMLQDCLDEVEAADKAGFSTVWLTEHHFLEEYCHSTAPEIFLAAASQRTK NIRLGFGIMHLPPAVNHPARVAERIATLDLLSNGRVEFGTGESSSIGELGGFNIDPADKRGQWEEALEVA IRCMIEEPFAGFTGDHIQMPARNVIPKPMQKPHPPVWVACTRPATVQMAAQKCIGALSFAYTGPGPLTER VNGYYKEFEENGTPVTPAINPNILAIGGDLSMMVAKTDEQALQRLGQGGGFFSFGIMHYYMTGIHTPGRT GVWTRYLEEIEKDPTLAYGPGRGAIGCPATVREFLRGYEESGVDEIILLLNPRSHEGTMESIELMGKEVL PEFIERDAKAVADKAVRLAPAIEKVQARRQESNAPQFDEAYSFGGLPTGRGGKFTASEIPEAMAEINEGR VQAAQRLKEQRK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4774 | - | - | 100% (433) | monoxygenase |
| M. marinum M | MMAR_2824 | - | 2e-22 | 28.65% (370) | monooxygenase |
| M. marinum M | MMAR_5115 | - | 5e-22 | 26.94% (412) | monooxygenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1971 | - | 2e-16 | 26.92% (364) | monooxygenase |
| M. gilvum PYR-GCK | Mflv_2404 | - | 0.0 | 81.02% (432) | luciferase family protein |
| M. tuberculosis H37Rv | Rv3618 | - | 4e-19 | 31.91% (188) | monooxygenase |
| M. leprae Br4923 | MLBr_00269 | - | 3e-05 | 21.99% (191) | putative F420-dependent glucose-6-phosphate dehydrogenase |
| M. abscessus ATCC 19977 | MAB_0527c | - | 1e-23 | 29.36% (344) | monooxygenase |
| M. avium 104 | MAV_0881 | - | 0.0 | 92.61% (433) | hypothetical protein MAV_0881 |
| M. smegmatis MC2 155 | MSMEG_4863 | - | 0.0 | 81.99% (433) | hypothetical protein MSMEG_4863 |
| M. thermoresistible (build 8) | TH_3770 | - | 0.0 | 83.29% (431) | PUTATIVE luciferase family protein |
| M. ulcerans Agy99 | MUL_0345 | - | 0.0 | 99.54% (433) | monoxygenase |
| M. vanbaalenii PYR-1 | Mvan_4242 | - | 0.0 | 80.56% (432) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Rv3618|M.tuberculosis_H37Rv MKAP-LRFGVFITPFHPTGQSPTVALQYDMERVVALDRLGYDEAWFGEHH
MAB_0527c|M.abscessus_ATCC_199 MSAPPLRFGAFITPFHPVGQNPTTALEYDLDRVVALDRLGYHEAWFGEHH
MMAR_4774|M.marinum_M MKIS--LFYEFALPRPWAPDDERIMLQDCLDEVEAADKAGFSTVWLTEHH
MUL_0345|M.ulcerans_Agy99 MKIS--LFYEFALPRPWAPNDERIMLQDCLDEVEAADKAGFSTVWLTEHH
MAV_0881|M.avium_104 MKIS--LFYEFALPRPWAPDDEHVLLQECLDEVEAADKAGFSTVWLTEHH
Mflv_2404|M.gilvum_PYR-GCK MKIS--LFYEFPLPRPWSDDDEHQLFQHGLDEVELADKAGFSTVWLTEHH
Mvan_4242|M.vanbaalenii_PYR-1 MKIS--LFYEFPLPRPWSEDDEHQLFQHGLDEVELADKAGFSTVWLTEHH
MSMEG_4863|M.smegmatis_MC2_155 MKIS--LFYEFPLPRPWSEDDEHQLFQHGLDEVELADKAGFSTVWLTEHH
TH_3770|M.thermoresistible__bu MKIS--LFYEFPLPRPWSEDDEHKLFQDGLDEVEAADKAGFSSVWLTEHH
Mb1971|M.bovis_AF2122/97 MEIG-----IFLMPAHPPERTLYDATRWDLDVIELADQLGYVEAWVGEHF
MLBr_00269|M.leprae_Br4923 ---------MAELRLGYKASAEQFAPRELVELGVAAEAHGMDSATVSDHF
. :: : * . . :*.
Rv3618|M.tuberculosis_H37Rv S-GGYEL--IACPEVFIAAAAERTTHIRLGTGVVSLP--YHHPLMVADRW
MAB_0527c|M.abscessus_ATCC_199 S-GGYEL--ISCPEVFIATAAERTKHIKLGTGVVSLP--YHHPLMVVDRW
MMAR_4774|M.marinum_M FLEEYCH--STAPEIFLAAASQRTKNIRLGFGIMHLPPAVNHPARVAERI
MUL_0345|M.ulcerans_Agy99 FLEEYCH--STAPEIFLAAASQRTKNIRLGFGIMHLPPAVNHPARVAERI
MAV_0881|M.avium_104 FLEEYCH--STAPEIFLAAASQRTENIRLGFGIMHLPPAVNHPARVAERI
Mflv_2404|M.gilvum_PYR-GCK FLEEYCH--STAPELFLAAASQRTKNIRLGFGVMHLPPPINHPARIAERV
Mvan_4242|M.vanbaalenii_PYR-1 FLEEYCH--STAPELFLAAASQRTKNIRLGFGVMHLPPPINHPARIAERV
MSMEG_4863|M.smegmatis_MC2_155 FLEEYCH--STAPEMFLAAASQRTENIRLGFGVMHLPPPINHPARIAERV
TH_3770|M.thermoresistible__bu FLEEYCH--STAPEMFLAAASQRTENIRLGFGVMHLPPPINHPARIAERV
Mb1971|M.bovis_AF2122/97 T-VPWEP--ICAPDLLLAQALLRTQQIKLAPGAHLLP--YHHPVELAHRV
MLBr_00269|M.leprae_Br4923 QPWRHQGGHASFSLSWMTAVGERTNRILLGT-SVLTPTFRYNPAVIGQAF
. :: . ** .* *. * :* : .
Rv3618|M.tuberculosis_H37Rv VLLDHLTRGRVMFGTGPGALPSDAYM--MGIDP--VEQRRMMQESLEAIL
MAB_0527c|M.abscessus_ATCC_199 ILLDHITRGRVIFGTGPGALPTDAYM--MGIDP--VDQRRMQEESLEAIL
MMAR_4774|M.marinum_M ATLDLLSNGRVEFGTGESSSIGELGG--FNIDP--ADKRGQWEEALEVAI
MUL_0345|M.ulcerans_Agy99 ATLDLLSNGRVEFGTGESSSIGELGG--FNIDP--TDKRGQWEEALEVAI
MAV_0881|M.avium_104 ATLDLLSNGRVEFGTGESSSVGELGG--FNIDP--ADKRAQWEEALEVAI
Mflv_2404|M.gilvum_PYR-GCK ATLDHLSNGRVEFGTGEGSSVAELGG--FNIDP--ADKRAQWEEALEVSI
Mvan_4242|M.vanbaalenii_PYR-1 ATLDHLSNGRVEYGTGEGSSVAELGG--FNIDP--ADKRTMWEEALEVSI
MSMEG_4863|M.smegmatis_MC2_155 ATLDHLSNGRVEFGTGEGSSVAELGG--FNIDP--ADKRTQWEESLEVAI
TH_3770|M.thermoresistible__bu ATLDHLSNGRVEFGTGEGSSVAELGG--FNIDP--ADKRTMWEEALEVSI
Mb1971|M.bovis_AF2122/97 AYFDHLAQGRFMLGVGASGIPGDWAL--YDVDGKNGEHREMTREALEIML
MLBr_00269|M.leprae_Br4923 ATMGCLYPNRVFLGVGTGEALNEVATGYQGAWPEFKERFARLRESVRLMR
:. : .*. *.* . : . :: .*::.
Rv3618|M.tuberculosis_H37Rv ALFRAAPDERIDRHSDWFTLR--------EAQLHIRPYTWPYPEIATAAM
MAB_0527c|M.abscessus_ATCC_199 ALLRATPQERINRETSWFTLR--------DAQLQLRPYTHPYPEILTAAM
MMAR_4774|M.marinum_M RCMIEEPFAGFT--GDHIQMP--------ARNVIPKPMQKPHPPVWVACT
MUL_0345|M.ulcerans_Agy99 RCMIEEPFAGFT--GDHIQMP--------ARNVIPKPMQKPHPPVWVACT
MAV_0881|M.avium_104 RCMVEEPFSGFH--GEHVQMP--------ARNVIPKPLQKPHPPVWVACT
Mflv_2404|M.gilvum_PYR-GCK RCMTEAPFTGFK--GEHVEMP--------ARNVIPKPLQQPHPPVWVACT
Mvan_4242|M.vanbaalenii_PYR-1 RCMTEAPFTGFK--GEHVEMA--------ARNVIPKPLQQPHPPVWVACT
MSMEG_4863|M.smegmatis_MC2_155 RCMVEEPFSGFK--GEHVEMP--------ARNVIPKPLQKPHPPVWVACT
TH_3770|M.thermoresistible__bu RCMIEEPFSGFK--GEHVEMP--------ARNVIPKPLQKPHPPVWVACT
Mb1971|M.bovis_AF2122/97 RIWTEDEPWEHR--GKYWNANGIAPMFEGLMRRHIKPYQKPHPPIGVTGF
MLBr_00269|M.leprae_Br4923 ELWRGD---RVDFDGDYYQLK----------GASIYDVPEGGVPIYIAAG
. : :
Rv3618|M.tuberculosis_H37Rv IS-PSGPRLAGALGTSLLSLSMSVPGGYAALETAWGVVREQAAKAGRGEP
MAB_0527c|M.abscessus_ATCC_199 FS-PSGPRLAGKLGAGLLSLSASIPGGFAALENAWEVVREQAEIHGHPEP
MMAR_4774|M.marinum_M R--PATVQMAAQKCIGALSFAYTGPGPLTERVNGYYKEFEENGTPVTPAI
MUL_0345|M.ulcerans_Agy99 R--PATVQMAAQKCIGALSFAYTGPGPLTERVNGYYKEFEENGTPVTPAI
MAV_0881|M.avium_104 R--PASVQMAAQKAIGALSFAYTGPGPLTERVNGYYKEFEENGVPVTPAI
Mflv_2404|M.gilvum_PYR-GCK R--PSSVGMAAEKAIGALSFAYTGPEALKDRVDGYYKDFEEKGTPITPAI
Mvan_4242|M.vanbaalenii_PYR-1 R--PSSVQMAAQKAIGALSFAYTGPEALKERVDGYYKEFEEQGAPITPAI
MSMEG_4863|M.smegmatis_MC2_155 R--PSSVQMAAQKAIGALSFAYTGPEALKERVAGYYKEFEEQGAPVTPAI
TH_3770|M.thermoresistible__bu R--PSSVQMAAQKAIGALSFAYTGPGPLKERVDGYYKEFEEKGSPVTPAV
Mb1971|M.bovis_AF2122/97 SAGSETLKLAGERGYIPMSLDLN-----TEYVATHWDAVEEGALRSGRTP
MLBr_00269|M.leprae_Br4923 G--PEVAKYAGRAGEGFVCTSGKGEELYTEKLIP--AVLEGAAVAGR---
. *. :. . *
Rv3618|M.tuberculosis_H37Rv DRADWRVLSIMHLSDSRDQAIDDCTYG-LPDFSRYFGAAGFVPLANTVEG
MAB_0527c|M.abscessus_ATCC_199 DRSSWRVLGIMHLAETRDQAIADCTYG-LPDYAHYFGAVGVLPLANSADG
MMAR_4774|M.marinum_M NPNILAIGGDLSMMVAKTDEQALQRLG-QGGGFFSFGIMHYYMTGIHTPG
MUL_0345|M.ulcerans_Agy99 NPNILAIGGDLSMMVAKTDEQALQRLG-QGGGFFSFGIMHYYMTGIHTPG
MAV_0881|M.avium_104 NPNILAIGGDLSMMVAKTDEEALQRLG-KGGGFFSFGIMHYYMTGVHTPG
Mflv_2404|M.gilvum_PYR-GCK NPNLLAIGGDLSMMVAKTDEEALKRLG-IGGGFFSFGIMHYYLTGMHTPG
Mvan_4242|M.vanbaalenii_PYR-1 NPNILAIGGDLSMMVAKTDEEALERLG-IGGGFFSFGIMHYYLTGMHTPG
MSMEG_4863|M.smegmatis_MC2_155 NPNILAIGGDLSMMVARTDEEALKRLG-IGGGFFSFGIMHYYLTGMHTPG
TH_3770|M.thermoresistible__bu NPNILAIGGDLSMMVAKTDEEALKRLG-IGGGFFSFGIMHYYMTGMHTPG
Mb1971|M.bovis_AF2122/97 DRRDWRLVREVLVAETDEQAFRYAVDGTMGRAMREYVLPTFRMFGMTKFY
MLBr_00269|M.leprae_Br4923 DADDIDKMIEIKMSYDPDPEQALSNIR----FWAPLSLAAEQKHSIDDPI
: : : .
Rv3618|M.tuberculosis_H37Rv TQ----SSREFVEQYAAKGNCCIGTPDDAIAHIEDLLHRSGGFG----TL
MAB_0527c|M.abscessus_ATCC_199 ADGA-IDPHEFVKAYADEGNCCIGTPEDAIEYIQGLLDTSGGFG----TF
MMAR_4774|M.marinum_M RTG---VWTRYLEEIEKDPTLAYGPGRGAIGCPATVREFLRGYEESGVDE
MUL_0345|M.ulcerans_Agy99 RTG---VWTRYLEEIEKDPTLAYGPGRGAIGCPATVREFLRGYEESGVDE
MAV_0881|M.avium_104 RTG---VWKRYLEEVEKDPTLAYGPGRGAIGSPATVREFLRGYEESGVDE
Mflv_2404|M.gilvum_PYR-GCK RTG---VWELYEKAVKEDPTLAYGPGRGAIGSPETVREFLRGYEASGVDE
Mvan_4242|M.vanbaalenii_PYR-1 RTG---VWELYEKAVKEDPTLAYGPGRGAIGSPDTVREFLRGYEASGVDE
MSMEG_4863|M.smegmatis_MC2_155 RTK---VWERYEQAVADDPTLAYGPGRGAIGSPETVREFLRGYEASGVDE
TH_3770|M.thermoresistible__bu RTG---VWELYEQAVKEDPTLAYGPGRGAIGSPETVREFLRGYEESGVDE
Mb1971|M.bovis_AF2122/97 KHNPSVPDDEVTPEYLAENTFVVGSVQTVVDKLEATYDQVGGFG----HL
MLBr_00269|M.leprae_Br4923 EMEK--VADALPIEQVAKRWIVVSDPDEAVARVGQYVTWG----------
. . .:
Rv3618|M.tuberculosis_H37Rv LLLGHDWAPPPATFHS-YELFARAVIPYFKG--------QLAAPRASHEW
MAB_0527c|M.abscessus_ATCC_199 LMLGHDWAAPEATFKS-YELFARKVIPHFTG--------QLTAAQASHDW
MMAR_4774|M.marinum_M IILLLNPRSHEGTMES-IELMGKEVLPEFIERDAKAVADKAVRLAPAIEK
MUL_0345|M.ulcerans_Agy99 IILLLNPRSHEGTMES-IELMGKEVLPEFIERDAKAVADKAVRLAPAIEK
MAV_0881|M.avium_104 IILLLNPRSHEGTMES-IELMGKEVLPEFIERDAKAVADKATRLAPVIEK
Mflv_2404|M.gilvum_PYR-GCK IILLLNPRSHEGTMES-IEIMGRDILPEFIERDEKAVKDKAKRLEPVIEK
Mvan_4242|M.vanbaalenii_PYR-1 IILLLNPRSHEGTMES-IEIMGRDILPEFIERDEKAVKDKAKRLEPVIEK
MSMEG_4863|M.smegmatis_MC2_155 IILLLNPRSHEGTMES-IEIMGKEILPEFIERDEKAVKDKAERLEPVVEK
TH_3770|M.thermoresistible__bu IILLLNPRSHEGTMES-IEIMGREILPEFIEREEKAQVEKAKRLEPVLEK
Mb1971|M.bovis_AF2122/97 LILGFDYSDNPGPWKESLRLLAHEVMPRLNAR---------LATKPATAV
MLBr_00269|M.leprae_Br4923 -LNHLVFHAPGHNQRRFLELFEKDLAPRLRRLG-----------------
: . .:: : : * :
Rv3618|M.tuberculosis_H37Rv ARGKR---------------DQLIGRAGEAVVKAITEHVAEQGEAGS---
MAB_0527c|M.abscessus_ATCC_199 AQAKR---------------GELLGRAGDAVAKAIGEHVAQKASH-----
MMAR_4774|M.marinum_M VQARRQESNAPQFDEAYSFGGLPTGRGGKFTASEIPEAMAEINEGRVQAA
MUL_0345|M.ulcerans_Agy99 VQARRQESNAPQFDEAYSFGGLPTGRGGKFTASEIPEAMAEINEGRVQAA
MAV_0881|M.avium_104 VEARRPKSTAPQFDENYSFGGLPTGRGGKFTASEIPEAMAEINEGRVQAA
Mflv_2404|M.gilvum_PYR-GCK VEARRQSWDAPMFDETYSFGGLPTGRGGKFTAGEIPEAMAEINEGRVKAA
Mvan_4242|M.vanbaalenii_PYR-1 VEARRQSWDAPLFDETYAFGGLPTGRGGKFTAGEIPEAMAEINEGRVKAA
MSMEG_4863|M.smegmatis_MC2_155 VESRRQGSDAPLFDETYAFGGLPTGRGGKFTAGEIPEAMAEINEGRVKAA
TH_3770|M.thermoresistible__bu VEARRKPSEAPEFDETYSFGGLPTGRGGKFTASEIPEAMAEINEGRVQAA
Mb1971|M.bovis_AF2122/97 V-------------------------------------------------
MLBr_00269|M.leprae_Br4923 --------------------------------------------------
Rv3618|M.tuberculosis_H37Rv -----------------
MAB_0527c|M.abscessus_ATCC_199 -----------------
MMAR_4774|M.marinum_M QRLK------EQRK---
MUL_0345|M.ulcerans_Agy99 QRLK------EQRK---
MAV_0881|M.avium_104 QRAK------EQQQQKK
Mflv_2404|M.gilvum_PYR-GCK QAEKDARAAKEAAG---
Mvan_4242|M.vanbaalenii_PYR-1 QAEKDAKAAKEAAS---
MSMEG_4863|M.smegmatis_MC2_155 QAEK---AAREAAG---
TH_3770|M.thermoresistible__bu KKAK------EQAS---
Mb1971|M.bovis_AF2122/97 -----------------
MLBr_00269|M.leprae_Br4923 -----------------