For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
GRVALTESDEYARQYFDEQAESNKEYWRRFGVVPDWAGKRVLDVGCGHGALSIDIAQAGASVLGVDLDEG RVAFANRNLAQRFPELADRVRFRAVDVRSLPVDEPFDVIVSKDTFEHVADVATLLRALGERLTRPGGRIY AGFSPLYYSPFGDHGRTGLKVPWAHAILPKRLVFAAAARKYGHPVGSLLDIGLNGNTPDQFRAAFDNSGL RQLDIGYNRGAKRLLPALERARRHWRRFDRFTTVSIYAVFGV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4513 | - | - | 100% (253) | hypothetical protein MMAR_4513 |
| M. marinum M | MMAR_0008 | - | 8e-10 | 36.13% (119) | hypothetical protein MMAR_0008 |
| M. marinum M | MMAR_1663 | - | 4e-09 | 32.85% (137) | hypothetical protein MMAR_1663 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3064c | - | 8e-09 | 31.33% (166) | hypothetical protein Mb3064c |
| M. gilvum PYR-GCK | Mflv_4269 | - | 4e-08 | 34.58% (107) | methyltransferase type 11 |
| M. tuberculosis H37Rv | Rv3038c | - | 8e-09 | 31.33% (166) | hypothetical protein Rv3038c |
| M. leprae Br4923 | MLBr_01723 | - | 4e-08 | 33.33% (105) | hypothetical protein MLBr_01723 |
| M. abscessus ATCC 19977 | MAB_3364 | - | 2e-09 | 34.40% (125) | hypothetical protein MAB_3364 |
| M. avium 104 | MAV_4945 | - | 2e-09 | 33.56% (149) | SAM-dependent methyltransferase |
| M. smegmatis MC2 155 | MSMEG_2329 | - | 3e-08 | 30.46% (151) | methyltransferase, UbiE/COQ5 family protein |
| M. thermoresistible (build 8) | TH_2189 | - | 6e-09 | 31.79% (151) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_4684 | - | 1e-143 | 97.23% (253) | hypothetical protein MUL_4684 |
| M. vanbaalenii PYR-1 | Mvan_1888 | - | 7e-09 | 39.62% (106) | methyltransferase type 11 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3064c|M.bovis_AF2122/97 --------------------------------------------------
Rv3038c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01723|M.leprae_Br4923 --------------------------------------------------
Mflv_4269|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2329|M.smegmatis_MC2_155 --------------------------------------------------
TH_2189|M.thermoresistible__bu VIRRLMATALTALTTAVLAGCGDAGSWVEAKPAEGWSAQYGDAANSSYTS
MMAR_4513|M.marinum_M --------------------------------------------------
MUL_4684|M.ulcerans_Agy99 --------------------------------------------------
Mvan_1888|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3364|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4945|M.avium_104 --------------------------------------------------
Mb3064c|M.bovis_AF2122/97 --------------------------------------------------
Rv3038c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01723|M.leprae_Br4923 --------------------------------------------------
Mflv_4269|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2329|M.smegmatis_MC2_155 --------------------------------------------------
TH_2189|M.thermoresistible__bu AAGAEALTLEWSRSVKGELAAQVAVGASGYLAVNAQTPAGCSLMVWEYAN
MMAR_4513|M.marinum_M --------------------------------------------------
MUL_4684|M.ulcerans_Agy99 --------------------------------------------------
Mvan_1888|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3364|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4945|M.avium_104 --------------------------------------------------
Mb3064c|M.bovis_AF2122/97 --------------------------------------------------
Rv3038c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01723|M.leprae_Br4923 --------------------------------------------------
Mflv_4269|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2329|M.smegmatis_MC2_155 --------------------------------------------------
TH_2189|M.thermoresistible__bu SARQRWCTRLVQGGGRTSPLLDGFDNVYIGQPGAILSFPPTQWIRWRKPV
MMAR_4513|M.marinum_M --------------------------------------------------
MUL_4684|M.ulcerans_Agy99 --------------------------------------------------
Mvan_1888|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3364|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4945|M.avium_104 --------------------------------------------------
Mb3064c|M.bovis_AF2122/97 --------------------------------------------------
Rv3038c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01723|M.leprae_Br4923 --------------------------------------------------
Mflv_4269|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2329|M.smegmatis_MC2_155 --------------------------------------------------
TH_2189|M.thermoresistible__bu IGMPTTPRILAPGELLVVTHLGQVLLFDAHRGTVTGTPLDLVAGVDPTDS
MMAR_4513|M.marinum_M --------------------------------------------------
MUL_4684|M.ulcerans_Agy99 --------------------------------------------------
Mvan_1888|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3364|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4945|M.avium_104 --------------------------------------------------
Mb3064c|M.bovis_AF2122/97 ------------------------------------------MTRSSN--
Rv3038c|M.tuberculosis_H37Rv ------------------------------------------MTRSSN--
MLBr_01723|M.leprae_Br4923 ------------------------------------------MTRSTE--
Mflv_4269|M.gilvum_PYR-GCK ------------------------------------------MTETKEP-
MSMEG_2329|M.smegmatis_MC2_155 ------------------------------------------MTEIR---
TH_2189|M.thermoresistible__bu ERGLADCAGARXXXCWPPPRPPSTVTPRARDAARHPTARLPAMTETTEPG
MMAR_4513|M.marinum_M --------------------------------------------------
MUL_4684|M.ulcerans_Agy99 --------------------------------------------------
Mvan_1888|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3364|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4945|M.avium_104 --------------------------------------------------
Mb3064c|M.bovis_AF2122/97 -----IPADATPNPHATAEQVAAARHDSKLAQVLYHDWEAE--NYDEKWS
Rv3038c|M.tuberculosis_H37Rv -----IPADATPNPHATAEQVAAARHDSKLAQVLYHDWEAE--NYDEKWS
MLBr_01723|M.leprae_Br4923 -----ISANAVPNPHATAEQVAAARKDSKLAQVLYHDWEAE--NYDEKWS
Mflv_4269|M.gilvum_PYR-GCK -GAYPDVAVPAPTPHATKEQVEAALHDTKLAQVLYHDWEAE--TYDDKWS
MSMEG_2329|M.smegmatis_MC2_155 -----DAADPAPNPHATAEEVEAAMHDSKLAQVLYHDWEAE--TYDEKWS
TH_2189|M.thermoresistible__bu IGSEGAGDLPAPNPHATAEQVEAAMRDSKLAQILYHDWEAE--SYDDKWS
MMAR_4513|M.marinum_M -------------------MGRVALTESDEYARQYFDEQAE--SNKEYWR
MUL_4684|M.ulcerans_Agy99 -------------------MGRVALTESEEYARQYFDEQAE--SNNEYWR
Mvan_1888|M.vanbaalenii_PYR-1 --------------------------MDLTPRLSRFDEFYK--NQTPPWV
MAB_3364|M.abscessus_ATCC_1997 ----MNSHLTDPHPADPLRTSGPSAEDPDATLALTGERTVPGIAEENYWF
MAV_4945|M.avium_104 ---MTDIFARRATLARSVRLLSQFRYERSEPARFYGALAADTAAMVDDLW
Mb3064c|M.bovis_AF2122/97 ISYDQRCVDYARGRFDAIVPDEVIAQLPYDRALELGCGTGFFLLNLIQAG
Rv3038c|M.tuberculosis_H37Rv ISYDQRCVDYARGRFDAIVPDEVIAQLPYDRALELGCGTGFFLLNLIQAG
MLBr_01723|M.leprae_Br4923 ISYDQRCVDYVRHCFDAIVPDELFTELPYDCALELGCGTGFFLLNLIQSG
Mflv_4269|M.gilvum_PYR-GCK ISYDQRCVDYARGRFDAAVPEEVQRELPYDRALELGCGTGFFLLNLIQAG
MSMEG_2329|M.smegmatis_MC2_155 ISYDQRCIDYARGRFDAIVPEDEQRKLPYDRALELGCGTGFFLLNLIQSG
TH_2189|M.thermoresistible__bu ISYDQRCVDYARGRFDAIVPDHVQRELPYDNALELGCGTGFFLLNLIQSG
MMAR_4513|M.marinum_M R--------------FGVVPDWAG-----KRVLDVGCGHGALSIDIAQAG
MUL_4684|M.ulcerans_Agy99 R--------------FGVVPDWAG-----KRVLDVGCGHGALSIDIAQAG
Mvan_1888|M.vanbaalenii_PYR-1 IGEP-----------QQAIVELEQAGLIGGRVLDVGCGTGEHTILLARAG
MAB_3364|M.abscessus_ATCC_1997 RR-------------HEVVYERLSSLCAGRRVLEAGSGEGYGADMLAQVA
MAV_4945|M.avium_104 R-------------------AGHGESAAGRTLLDVGGGPGYFAAAFADAG
*: * * * : .
Mb3064c|M.bovis_AF2122/97 VARRGSVTDLSPGMVKVATRNGQA----LGLDIDGRVADAEGIPYDDDAF
Rv3038c|M.tuberculosis_H37Rv VARRGSVTDLSPGMVKVATRNGQA----LGLDIDGRVADAEGIPYDDDAF
MLBr_01723|M.leprae_Br4923 VARRGSVTDLSPGMVKIATRNGQS----LGLDINGRVADAEGIPYDDNTF
Mflv_4269|M.gilvum_PYR-GCK VARRGSVTDLSPGMVKVATRNGQS----LGLDIDGRVADAEGIPYEDNTF
MSMEG_2329|M.smegmatis_MC2_155 VARRGSVTDLSPGMVKVATRNGQS----LGLDIDGRVADAEGIPYEDDTF
TH_2189|M.thermoresistible__bu VARRGSVTDLSPGMVRVATRNGRS----LGLDVDGRVADAEGIPYDDNTF
MMAR_4513|M.marinum_M ASVLG--VDLDEGRVAFANRNLAQRFPELADRVRFRAVDVRSLPVDEP-F
MUL_4684|M.ulcerans_Agy99 ASVLG--VDLDEGRVAFANRNLAQRFPEQADRVRFRAVDVRSLPVDEP-F
Mvan_1888|M.vanbaalenii_PYR-1 YDVLG--IDGAPTAVEQARRNAEA----QGVDARFELADALHLG-PDPTY
MAB_3364|M.abscessus_ATCC_1997 QHVIG--LDYDESAIAHVKARYPR--------VDMRAGNLADLPLADGSV
MAV_4945|M.avium_104 VRYLG--VEPDPGEMHAAGPVVAA------DTGTFVRASGMALPFADDSV
* : : . . : :
Mb3064c|M.bovis_AF2122/97 DLVVGHAVLHHIPDVELS-LREVVRVLKPGGRFVFAGEPTTVGDGYARTL
Rv3038c|M.tuberculosis_H37Rv DLVVGHAVLHHIPDVELS-LREVVRVLKPGGRFVFAGEPTTVGDGYARTL
MLBr_01723|M.leprae_Br4923 DLVVGHAVLHHIPDVELS-LREVLRVLKPGGRFVFAGEPTDVGNRYARVF
Mflv_4269|M.gilvum_PYR-GCK DLVVGHAVLHHIPDVELS-LREVVRVLKPGGRFVFAGEPTTVGNRYAREL
MSMEG_2329|M.smegmatis_MC2_155 DLVVGHAVLHHIPDVELS-LREVVRILKPGGRFVFAGEPTTVGNRYAREL
TH_2189|M.thermoresistible__bu DLVVGHAVLHHIPDVELS-LREVVRVLRPGGRFVFAGEPTTVGNSYARAL
MMAR_4513|M.marinum_M DVIVSKDTFEHVADVATL-LRALGERLTRPGGRIYAGFSPLYYSPFG-DH
MUL_4684|M.ulcerans_Agy99 DVIVSKDTFEHVADVASL-LLALGERLTRPGGRIYAGFSPLYYSPFG-DH
Mvan_1888|M.vanbaalenii_PYR-1 DTIVDSALFHIFDDADRATYVRSLHAATRPGSVVHLLALSDSGRGFGPEV
MAB_3364|M.abscessus_ATCC_1997 DVVVNFQVIEHLWDQGQF-IRECARVLRPGGSLLIS-TPNRITFSPGRDT
MAV_4945|M.avium_104 DICLSSNVAEHVPR--PWQLGAEMLRVTRPGGLAVLSYTVWLGPFGGHEM
* :. . . * .
Mb3064c|M.bovis_AF2122/97 STLTWRVVTNATKLPGLRGWRRPQGELDESSRAAALEALVDLHTFTPQDL
Rv3038c|M.tuberculosis_H37Rv STLTWRVVTNATKLPGLRGWRRPQGELDESSRAAALEALVDLHTFTPQDL
MLBr_01723|M.leprae_Br4923 ADLTWKVTIRVVQLPGLSAWRRTQVEIDENSRAAALEWVVDLHTFEPKVL
Mflv_4269|M.gilvum_PYR-GCK STLTWHAATNIMKLPMLSDWRRPQAELDESSRAAALEAVVDLHTFDPADL
MSMEG_2329|M.smegmatis_MC2_155 STLTWHATTNLTKLPFLSGWRRPQEELDESSRAAALEAVVDLHTFDPADL
TH_2189|M.thermoresistible__bu STLTWHVATTVTRLPGLQGWRRPQAELDESSRAAALEAVVDLHTFEPSDL
MMAR_4513|M.marinum_M GRTGLKVPWAHAILP----------------KRLVFAAAARKYGHPVGSL
MUL_4684|M.ulcerans_Agy99 GRTGLKVPWTHAILP----------------KRLVFAVAARKYGHPVGSL
Mvan_1888|M.vanbaalenii_PYR-1 SEHTIRAAFG--------------------------------AGWEVEAL
MAB_3364|M.abscessus_ATCC_1997 PLNPFHTRELN---------------------GAELTELLEENGFSLESM
MAV_4945|M.avium_104 GLTHYLGGSR------------------------AAARYARKHGHPAKNN
Mb3064c|M.bovis_AF2122/97 QRIAHNAGAVEVQTATEEFTAAMLGWPLRTFECTVPPGRLGWGWARFAFT
Rv3038c|M.tuberculosis_H37Rv QRIAHNAGAVEVQTATEEFTAAMLGWPLRTFECTVPPGRLGWGWARFAFT
MLBr_01723|M.leprae_Br4923 ETMATNAGAVQVKTVTEEFTAAMLGWPLRTFESTMPPSKLGWGWARFAFT
Mflv_4269|M.gilvum_PYR-GCK ERMAANAGAVEVRTASEEFTAAMLGWPVRTFEAAVPPGRLGWGWAKFAFG
MSMEG_2329|M.smegmatis_MC2_155 ERMATNAGAVEVRTASEEFTAAMLGWPVRTFEAAVPPGRLGWGWAKFAFN
TH_2189|M.thermoresistible__bu ERMARNAGAVEVATASEEFTAAMLGWPVRTFEAAVPPGKLGWNWAKFAFG
MMAR_4513|M.marinum_M LDIGLNG------NTPDQFRAAFDNSGLR---------QLDIGYNRGAKR
MUL_4684|M.ulcerans_Agy99 LDIGLNG------NTPDQFRAAFDNSGLR---------QLDIGYNRGAKR
Mvan_1888|M.vanbaalenii_PYR-1 TETTYRG------VVIDAHTEALN--------------------------
MAB_3364|M.abscessus_ATCC_1997 NGVFHGP---RLRELDAKYGGSIIDAQIER-------AVAGAPWPQELLA
MAV_4945|M.avium_104 YGSSLFEVSVADGLAWAACTGAELAAFPR--------------YHPRWAW
:
Mb3064c|M.bovis_AF2122/97 SWKTLGWVDANVWRHVVPKGWFYNVMITGVKPS
Rv3038c|M.tuberculosis_H37Rv SWKTLGWVDANVWRHVVPKGWFYNVMITGVKPS
MLBr_01723|M.leprae_Br4923 SWKTLSWVDANVWRRVIPKSWFYNIIITGVKPS
Mflv_4269|M.gilvum_PYR-GCK SWTTLSWVDANVWRRIVPKGWFYNVMVTGVKPS
MSMEG_2329|M.smegmatis_MC2_155 SWTTLSWVDANVWRKVVPKGWFYNVMVTGVKPS
TH_2189|M.thermoresistible__bu SWTALSWVDANVWRRVMPKGWFYNVMVTGVKPS
MMAR_4513|M.marinum_M LLPALERARR-HWRRFDRFTTVSIYAVFGV---
MUL_4684|M.ulcerans_Agy99 LLPALERARR-HWRRFDRFTTVSIYAVFGV---
Mvan_1888|M.vanbaalenii_PYR-1 -LPAGTVVDEPAWSARIRRL-------------
MAB_3364|M.abscessus_ATCC_1997 DITGLTTEDFEIVDAGERDIDASLDLVAIAVIP
MAV_4945|M.avium_104 WLTSVPVLREFLVSNLVLVLQPQ----------