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M. marinum M MMAR_4222 (-)

annotation: integral membrane protein
coordinates: 5200176 - 5200850
length: 224

MKTVVRVALSSIVGLVAFGLIVFIPAGTFDYWQAWVFMAVFAVATLVPSIYLGRTNPAALQRRMHAGPRA
ESRGIQKVIITAAFVALFAMVALSALDHRFGWSSVPTAVCLIGDLLIATGLGIAMLVVIQNGYAAATITV
ESDQKVVSTGLYSLVRHPMYVGNVILMLGIPLALGSYWGLVIVPPSVLVLAFRILDEESALVDQLDGYRD
YMQQVRYRLLPRVW
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_4222--100% (224)integral membrane protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1248c-1e-8163.18% (220) integral membrane protein
M. gilvum PYR-GCK-----
M. tuberculosis H37RvRv1216c-1e-8163.18% (220) integral membrane protein
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4689c-1e-7758.48% (224) hypothetical protein MAB_4689c
M. avium 104MAV_1360-3e-8566.52% (224) isoprenylcysteine carboxyl methyltransferase (icmt) family
M. smegmatis MC2 155MSMEG_5077-6e-6752.23% (224) integral membrane protein
M. thermoresistible (build 8)TH_0548-1e-6150.91% (220) PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN
M. ulcerans Agy99MUL_4523-1e-12299.11% (224) integral membrane protein
M. vanbaalenii PYR-1Mvan_4501-2e-7058.48% (224) isoprenylcysteine carboxyl methyltransferase

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_5077|M.smegmatis_MC2_155      MKLL------LQAVASGVFGLAFFAVALFWPAGTFDYWQAWVFIAVFLAG
Mvan_4501|M.vanbaalenii_PYR-1       MKLV------AQTLASSVLGAAYFVAVLFWPAGTFDYWQAWVFLAVFIVT
MMAR_4222|M.marinum_M               MKTV------VRVALSSIVGLVAFGLIVFIPAGTFDYWQAWVFMAVFAVA
MUL_4523|M.ulcerans_Agy99           MKTV------VRVALSSIVGLVAFGLIVFIPAGTFDYWQARVFMAVFAVA
MAV_1360|M.avium_104                MKTG------LRVTATSVWGILSWILILLLPAGTLHYWQAWVFIAVFTVA
Mb1248c|M.bovis_AF2122/97           MHIG------LKIFIWGVLGLVVFGALLFGPAGTFDYWQAWVFLAAFVST
Rv1216c|M.tuberculosis_H37Rv        MHIG------LKIFIWGVLGLVVFGALLFGPAGTFDYWQAWVFLAAFVST
MAB_4689c|M.abscessus_ATCC_199      MKTGGLVKAIAKVVAFGVVELAVFGLVLFLLAGTVDYWQVWTFLVVFALS
TH_0548|M.thermoresistible__bu      VY--------LRTTIYSVFGMVLFGALMFGPAGTLGYWQGWALLAVLVAF
                                    :          :    .:     :   ::  ***. ***  .::..:   

MSMEG_5077|M.smegmatis_MC2_155      TLIPSFYLAVTDPVTLQRRLHAGPTAETRSAQKVAAVALVVAVLAVLIVS
Mvan_4501|M.vanbaalenii_PYR-1       TLGPTFFLAVRHPDALARRMKAGPTAETRPAQRLIITLTVVLVTATFVLS
MMAR_4222|M.marinum_M               TLVPSIYLGRTNPAALQRRMHAGPRAESRGIQKVIITAAFVALFAMVALS
MUL_4523|M.ulcerans_Agy99           TLVPSIYLGRTNPAALQRRMHAGPRAESRGIQKVIITAAFVALFAMVALS
MAV_1360|M.avium_104                TIVPAAYLARTNPAALQRRMRAGPRAEPRTAQKFIITGSFLSLFAAMVFS
Mb1248c|M.bovis_AF2122/97           TIGPTIYLARNDPAALQRRMRSGPLAEGRTIQKFIVIGAFLGFFAMMVLS
Rv1216c|M.tuberculosis_H37Rv        TIGPTIYLARNDPAALQRRMRSGPLAEGRTIQKFIVIGAFLGFFAMMVLS
MAB_4689c|M.abscessus_ATCC_199      TWIPTVYLQRADPAAHQRRKRAGPVAETRSLQKVLIGSWYFSLAAMVVIS
TH_0548|M.thermoresistible__bu      TVPYTVYLAVKMPDTLRRRLRSGPTAESRPAQRAAILVVQLAALGMLVLG
                                    *   : :*    * :  ** ::** ** *  *:       .   . . ..

MSMEG_5077|M.smegmatis_MC2_155      ALDRRFGWSSVPAWLALAADVVVVVSLVLSQVVIFQNRFAAATIRVEAEQ
Mvan_4501|M.vanbaalenii_PYR-1       ALDHRFGWSSAPAWVVVVGNTLVALGLSGAQLVVVQNHYAAATVRVEAGQ
MMAR_4222|M.marinum_M               ALDHRFGWSSVPTAVCLIGDLLIATGLGIAMLVVIQNGYAAATITVESDQ
MUL_4523|M.ulcerans_Agy99           ALDHRFGWSSVPTAVCLIGDLLIATGLGIAMLVVIQNGYAAATITVECDQ
MAV_1360|M.avium_104                ALDHRFGWSSVPAWLSLLGDVLVATGLGIAMLVVIQNSYAAATVTVEAGQ
Mb1248c|M.bovis_AF2122/97           ACDHRYGWSSVPAAVCVIGDVLVMTGLGIAMLVVIQNRYAASTVRVEAGQ
Rv1216c|M.tuberculosis_H37Rv        ACDHRYGWSSVPAAVCVIGDVLVMTGLGIAMLVVIQNRYAASTVRVEAGQ
MAB_4689c|M.abscessus_ATCC_199      ALDHRFGWSSVPPAICAAGDVLVAVGLGVTSLVVVQNGFAASTVRVETGQ
TH_0548|M.thermoresistible__bu      GLDHRLGWSRAPVWVCVVGLVLTAAGLAITMGSVLQNAWAAATVTTESDQ
                                    . *:* *** .*  :   .  :   .*  :   :.** :**:*: .*  *

MSMEG_5077|M.smegmatis_MC2_155      QVISTGMYGWVRHPMYSWALVMILASPLALGSFWALLAATAGLPVLVFRI
Mvan_4501|M.vanbaalenii_PYR-1       PLVSTGLYGLVRHPMYTGTVVMMLGTPLALGSLWGLLGVAASAPVLVARI
MMAR_4222|M.marinum_M               KVVSTGLYSLVRHPMYVGNVILMLGIPLALGSYWGLVIVPPSVLVLAFRI
MUL_4523|M.ulcerans_Agy99           KVVSTGLYSLVRHPMYVGNVILMLGIPLALGSYWGLVIVPPSVLVLAFRI
MAV_1360|M.avium_104                TVVSSGLYRFVRHPMYTGNVIMMIGIPLALGSYWGLLFVVPGTALLALRI
Mb1248c|M.bovis_AF2122/97           ILASDGLYKIVRHPMYAGNVVMMTGIPLALGSYWAMFILVPGTLVLVFRI
Rv1216c|M.tuberculosis_H37Rv        ILASDGLYKIVRHPMYAGNVVMMTGIPLALGSYWAMFILVPGTLVLVFRI
MAB_4689c|M.abscessus_ATCC_199      TLVTTGLYGLVRHPMYTGNFITIVGFPLALGSYWGLACVVPSLLVLIVRI
TH_0548|M.thermoresistible__bu      QVVSTGLYGVVRHPLYAGSVVLFLGMPLALGSYWALALVVVAVAGLVVRI
                                     : : *:*  ****:*   .: : . ****** *.:     .   *  **

MSMEG_5077|M.smegmatis_MC2_155      LDEEKMLVAELRGYDEYRQKIRYRLVPGVW
Mvan_4501|M.vanbaalenii_PYR-1       LDEEKMLTAELAGYREYRRQVRYRLVPGVW
MMAR_4222|M.marinum_M               LDEESALVDQLDGYRDYMQQVRYRLLPRVW
MUL_4523|M.ulcerans_Agy99           LDEESALVDQLDGYRDYMQQVRYRLLPRVW
MAV_1360|M.avium_104                FDEEKLLLQELPGYPDYTQKVRYRLAPHLW
Mb1248c|M.bovis_AF2122/97           LDEEKLLTQELSGYREYRQLVRYRLVPYVW
Rv1216c|M.tuberculosis_H37Rv        LDEEKLLTQELSGYREYRQLVRYRLVPYVW
MAB_4689c|M.abscessus_ATCC_199      VDEEKLLVEELDGYRAYTRAARYRLMPYVW
TH_0548|M.thermoresistible__bu      LDEEALLRTELAGYPDYTRAVPYRLVPYVW
                                    .***  *  :* **  * :   *** * :*