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KTGGLVKAIAKVVAFGVVELAVFGLVLFLLAGTVDYWQVWTFLVVFALSTWIPTVYLQRADPAAHQRRKR AGPVAETRSLQKVLIGSWYFSLAAMVVISALDHRFGWSSVPPAICAAGDVLVAVGLGVTSLVVVQNGFAA STVRVETGQTLVTTGLYGLVRHPMYTGNFITIVGFPLALGSYWGLACVVPSLLVLIVRIVDEEKLLVEEL DGYRAYTRAARYRLMPYVW*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4689c | - | - | 100% (230) | hypothetical protein MAB_4689c |
| M. abscessus ATCC 19977 | MAB_1357c | - | 5e-66 | 51.79% (224) | hypothetical protein MAB_1357c |
| M. abscessus ATCC 19977 | MAB_0356c | - | 1e-05 | 34.42% (154) | hypothetical protein MAB_0356c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1248c | - | 8e-74 | 58.45% (219) | integral membrane protein |
| M. gilvum PYR-GCK | Mflv_2834 | - | 0.0001 | 33.33% (111) | hypothetical protein Mflv_2834 |
| M. tuberculosis H37Rv | Rv1216c | - | 8e-74 | 58.45% (219) | integral membrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_4222 | - | 1e-77 | 58.48% (224) | integral membrane protein |
| M. avium 104 | MAV_1360 | - | 2e-69 | 56.70% (224) | isoprenylcysteine carboxyl methyltransferase (icmt) family |
| M. smegmatis MC2 155 | MSMEG_5077 | - | 2e-61 | 51.34% (224) | integral membrane protein |
| M. thermoresistible (build 8) | TH_0548 | - | 2e-54 | 47.95% (219) | PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN |
| M. ulcerans Agy99 | MUL_4523 | - | 6e-76 | 58.04% (224) | integral membrane protein |
| M. vanbaalenii PYR-1 | Mvan_4501 | - | 7e-65 | 55.80% (224) | isoprenylcysteine carboxyl methyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1248c|M.bovis_AF2122/97 MHIG------LKIFIWGVLGLVVFGALLFGPAGTFDYWQAWVFLAAFVST
Rv1216c|M.tuberculosis_H37Rv MHIG------LKIFIWGVLGLVVFGALLFGPAGTFDYWQAWVFLAAFVST
MMAR_4222|M.marinum_M MKTV------VRVALSSIVGLVAFGLIVFIPAGTFDYWQAWVFMAVFAVA
MUL_4523|M.ulcerans_Agy99 MKTV------VRVALSSIVGLVAFGLIVFIPAGTFDYWQARVFMAVFAVA
MAV_1360|M.avium_104 MKTG------LRVTATSVWGILSWILILLLPAGTLHYWQAWVFIAVFTVA
MAB_4689c|M.abscessus_ATCC_199 MKTGGLVKAIAKVVAFGVVELAVFGLVLFLLAGTVDYWQVWTFLVVFALS
MSMEG_5077|M.smegmatis_MC2_155 MKLL------LQAVASGVFGLAFFAVALFWPAGTFDYWQAWVFIAVFLAG
Mvan_4501|M.vanbaalenii_PYR-1 MKLV------AQTLASSVLGAAYFVAVLFWPAGTFDYWQAWVFLAVFIVT
TH_0548|M.thermoresistible__bu VY--------LRTTIYSVFGMVLFGALMFGPAGTLGYWQGWALLAVLVAF
Mflv_2834|M.gilvum_PYR-GCK --------------MAAIGALALYLMFVALGFG----WRSWRQYRLTGST
.: : : * *:
Mb1248c|M.bovis_AF2122/97 TIGPTIYLARNDPAALQRRMRSGPLAEGRTIQKFIVIGAFLGFFAMMVLS
Rv1216c|M.tuberculosis_H37Rv TIGPTIYLARNDPAALQRRMRSGPLAEGRTIQKFIVIGAFLGFFAMMVLS
MMAR_4222|M.marinum_M TLVPSIYLGRTNPAALQRRMHAGPRAESRGIQKVIITAAFVALFAMVALS
MUL_4523|M.ulcerans_Agy99 TLVPSIYLGRTNPAALQRRMHAGPRAESRGIQKVIITAAFVALFAMVALS
MAV_1360|M.avium_104 TIVPAAYLARTNPAALQRRMRAGPRAEPRTAQKFIITGSFLSLFAAMVFS
MAB_4689c|M.abscessus_ATCC_199 TWIPTVYLQRADPAAHQRRKRAGPVAETRSLQKVLIGSWYFSLAAMVVIS
MSMEG_5077|M.smegmatis_MC2_155 TLIPSFYLAVTDPVTLQRRLHAGPTAETRSAQKVAAVALVVAVLAVLIVS
Mvan_4501|M.vanbaalenii_PYR-1 TLGPTFFLAVRHPDALARRMKAGPTAETRPAQRLIITLTVVLVTATFVLS
TH_0548|M.thermoresistible__bu TVPYTVYLAVKMPDTLRRRLRSGPTAESRPAQRAAILVVQLAALGMLVLG
Mflv_2834|M.gilvum_PYR-GCK GFHG----ISGRPGSPEWAAGVG------FVVAMVLGLLAPALQVFGVLA
* : * ..
Mb1248c|M.bovis_AF2122/97 ACDHRYGWSSVPAAVCVIGDVLVMTGLGIAMLVVIQNRYAAST-VRVEAG
Rv1216c|M.tuberculosis_H37Rv ACDHRYGWSSVPAAVCVIGDVLVMTGLGIAMLVVIQNRYAAST-VRVEAG
MMAR_4222|M.marinum_M ALDHRFGWSSVPTAVCLIGDLLIATGLGIAMLVVIQNGYAAAT-ITVESD
MUL_4523|M.ulcerans_Agy99 ALDHRFGWSSVPTAVCLIGDLLIATGLGIAMLVVIQNGYAAAT-ITVECD
MAV_1360|M.avium_104 ALDHRFGWSSVPAWLSLLGDVLVATGLGIAMLVVIQNSYAAAT-VTVEAG
MAB_4689c|M.abscessus_ATCC_199 ALDHRFGWSSVPPAICAAGDVLVAVGLGVTSLVVVQNGFAAST-VRVETG
MSMEG_5077|M.smegmatis_MC2_155 ALDRRFGWSSVPAWLALAADVVVVVSLVLSQVVIFQNRFAAAT-IRVEAE
Mvan_4501|M.vanbaalenii_PYR-1 ALDHRFGWSSAPAWVVVVGNTLVALGLSGAQLVVVQNHYAAAT-VRVEAG
TH_0548|M.thermoresistible__bu GLDHRLGWSRAPVWVCVVGLVLTAAGLAITMGSVLQNAWAAAT-VTTESD
Mflv_2834|M.gilvum_PYR-GCK PIAAFEAWG-----LQALGSVLALGGLAGTLYAQNDMGDSWRIGVDPQES
.*. : . : .* : : : : :
Mb1248c|M.bovis_AF2122/97 QILASDGLYKIVRHPMYAGNVVMMTGIPLALG--SYWAMFILVPGTLVLV
Rv1216c|M.tuberculosis_H37Rv QILASDGLYKIVRHPMYAGNVVMMTGIPLALG--SYWAMFILVPGTLVLV
MMAR_4222|M.marinum_M QKVVSTGLYSLVRHPMYVGNVILMLGIPLALG--SYWGLVIVPPSVLVLA
MUL_4523|M.ulcerans_Agy99 QKVVSTGLYSLVRHPMYVGNVILMLGIPLALG--SYWGLVIVPPSVLVLA
MAV_1360|M.avium_104 QTVVSSGLYRFVRHPMYTGNVIMMIGIPLALG--SYWGLLFVVPGTALLA
MAB_4689c|M.abscessus_ATCC_199 QTLVTTGLYGLVRHPMYTGNFITIVGFPLALG--SYWGLACVVPSLLVLI
MSMEG_5077|M.smegmatis_MC2_155 QQVISTGMYGWVRHPMYSWALVMILASPLALG--SFWALLAATAGLPVLV
Mvan_4501|M.vanbaalenii_PYR-1 QPLVSTGLYGLVRHPMYTGTVVMMLGTPLALG--SLWGLLGVAASAPVLV
TH_0548|M.thermoresistible__bu QQVVSTGLYGVVRHPLYAGSVVLFLGMPLALG--SYWALALVVVAVAGLV
Mflv_2834|M.gilvum_PYR-GCK TTLVRRGAFAVVRNPIFTAMLSFATGVALMVPNVLALAALILLVVAIELQ
: * : **:*:: . . .* : . *
Mb1248c|M.bovis_AF2122/97 FRILDEEKLLTQELSGYREYRQLVRYRLVPYVW-----------
Rv1216c|M.tuberculosis_H37Rv FRILDEEKLLTQELSGYREYRQLVRYRLVPYVW-----------
MMAR_4222|M.marinum_M FRILDEESALVDQLDGYRDYMQQVRYRLLPRVW-----------
MUL_4523|M.ulcerans_Agy99 FRILDEESALVDQLDGYRDYMQQVRYRLLPRVW-----------
MAV_1360|M.avium_104 LRIFDEEKLLLQELPGYPDYTQKVRYRLAPHLW-----------
MAB_4689c|M.abscessus_ATCC_199 VRIVDEEKLLVEELDGYRAYTRAARYRLMPYVW-----------
MSMEG_5077|M.smegmatis_MC2_155 FRILDEEKMLVAELRGYDEYRQKIRYRLVPGVW-----------
Mvan_4501|M.vanbaalenii_PYR-1 ARILDEEKMLTAELAGYREYRRQVRYRLVPGVW-----------
TH_0548|M.thermoresistible__bu VRILDEEALLRTELAGYPDYTRAVPYRLVPYVW-----------
Mflv_2834|M.gilvum_PYR-GCK VRVVEEPYLVHTHGDAYRSYGQAVG-RFLPVLGRFPRSVGGESR
*:.:* : . .* * : *: * :