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M. avium 104 MAV_1360 (-)

annotation: isoprenylcysteine carboxyl methyltransferase (icmt) family protein
coordinates: 1319039 - 1319713
length: 224

KTGLRVTATSVWGILSWILILLLPAGTLHYWQAWVFIAVFTVATIVPAAYLARTNPAALQRRMRAGPRAE
PRTAQKFIITGSFLSLFAAMVFSALDHRFGWSSVPAWLSLLGDVLVATGLGIAMLVVIQNSYAAATVTVE
AGQTVVSSGLYRFVRHPMYTGNVIMMIGIPLALGSYWGLLFVVPGTALLALRIFDEEKLLLQELPGYPDY
TQKVRYRLAPHLW*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. avium 104MAV_1360--100% (224)isoprenylcysteine carboxyl methyltransferase (icmt) family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1248c-4e-8164.29% (224) integral membrane protein
M. gilvum PYR-GCK-----
M. tuberculosis H37RvRv1216c-4e-8164.29% (224) integral membrane protein
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_1357c-1e-7357.14% (224) hypothetical protein MAB_1357c
M. marinum MMMAR_4222-4e-8566.52% (224) integral membrane protein
M. smegmatis MC2 155MSMEG_5077-7e-6651.34% (224) integral membrane protein
M. thermoresistible (build 8)TH_0548-6e-6050.91% (220) PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN
M. ulcerans Agy99MUL_4523-1e-8366.07% (224) integral membrane protein
M. vanbaalenii PYR-1Mvan_4501-1e-6957.59% (224) isoprenylcysteine carboxyl methyltransferase

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_4222|M.marinum_M               MKTVVRVALSSIVGLVAFGLIVFIPAGTFDYWQAWVFMAVFAVATLVPSI
MUL_4523|M.ulcerans_Agy99           MKTVVRVALSSIVGLVAFGLIVFIPAGTFDYWQARVFMAVFAVATLVPSI
MAV_1360|M.avium_104                MKTGLRVTATSVWGILSWILILLLPAGTLHYWQAWVFIAVFTVATIVPAA
Mb1248c|M.bovis_AF2122/97           MHIGLKIFIWGVLGLVVFGALLFGPAGTFDYWQAWVFLAAFVSTTIGPTI
Rv1216c|M.tuberculosis_H37Rv        MHIGLKIFIWGVLGLVVFGALLFGPAGTFDYWQAWVFLAAFVSTTIGPTI
MSMEG_5077|M.smegmatis_MC2_155      MKLLLQAVASGVFGLAFFAVALFWPAGTFDYWQAWVFIAVFLAGTLIPSF
Mvan_4501|M.vanbaalenii_PYR-1       MKLVAQTLASSVLGAAYFVAVLFWPAGTFDYWQAWVFLAVFIVTTLGPTF
MAB_1357c|M.abscessus_ATCC_199      MKTGAQALISGLTGLAVFGAALFWPAGTFHYWQAWVFLAIFVVCSGVSSI
TH_0548|M.thermoresistible__bu      --VYLRTTIYSVFGMVLFGALMFGPAGTLGYWQGWALLAVLVAFTVPYTV
                                         :    .: *   :   :: ****: ***. .::* :   :   : 

MMAR_4222|M.marinum_M               YLGRTNPAALQRRMHAGPRAESRGIQKVIITAAFVALFAMVALSALDHRF
MUL_4523|M.ulcerans_Agy99           YLGRTNPAALQRRMHAGPRAESRGIQKVIITAAFVALFAMVALSALDHRF
MAV_1360|M.avium_104                YLARTNPAALQRRMRAGPRAEPRTAQKFIITGSFLSLFAAMVFSALDHRF
Mb1248c|M.bovis_AF2122/97           YLARNDPAALQRRMRSGPLAEGRTIQKFIVIGAFLGFFAMMVLSACDHRY
Rv1216c|M.tuberculosis_H37Rv        YLARNDPAALQRRMRSGPLAEGRTIQKFIVIGAFLGFFAMMVLSACDHRY
MSMEG_5077|M.smegmatis_MC2_155      YLAVTDPVTLQRRLHAGPTAETRSAQKVAAVALVVAVLAVLIVSALDRRF
Mvan_4501|M.vanbaalenii_PYR-1       FLAVRHPDALARRMKAGPTAETRPAQRLIITLTVVLVTATFVLSALDHRF
MAB_1357c|M.abscessus_ATCC_199      YLARSNPAVLQRRLHGGPMAETRPVQKFAVTLLLSSFVALVVVSAFDHRF
TH_0548|M.thermoresistible__bu      YLAVKMPDTLRRRLRSGPTAESRPAQRAAILVVQLAALGMLVLGGLDHRL
                                    :*.   * .* **::.** ** *  *:           . . ... *:* 

MMAR_4222|M.marinum_M               GWSSVPTAVCLIGDLLIATGLGIAMLVVIQNGYAAATITVESDQKVVSTG
MUL_4523|M.ulcerans_Agy99           GWSSVPTAVCLIGDLLIATGLGIAMLVVIQNGYAAATITVECDQKVVSTG
MAV_1360|M.avium_104                GWSSVPAWLSLLGDVLVATGLGIAMLVVIQNSYAAATVTVEAGQTVVSSG
Mb1248c|M.bovis_AF2122/97           GWSSVPAAVCVIGDVLVMTGLGIAMLVVIQNRYAASTVRVEAGQILASDG
Rv1216c|M.tuberculosis_H37Rv        GWSSVPAAVCVIGDVLVMTGLGIAMLVVIQNRYAASTVRVEAGQILASDG
MSMEG_5077|M.smegmatis_MC2_155      GWSSVPAWLALAADVVVVVSLVLSQVVIFQNRFAAATIRVEAEQQVISTG
Mvan_4501|M.vanbaalenii_PYR-1       GWSSAPAWVVVVGNTLVALGLSGAQLVVVQNHYAAATVRVEAGQPLVSTG
MAB_1357c|M.abscessus_ATCC_199      GWSQAPTWLVIVGEVLTIGGLGMATLVVAQNNYAAASITVESGQTVTATG
TH_0548|M.thermoresistible__bu      GWSRAPVWVCVVGLVLTAAGLAITMGSVLQNAWAAATVTTESDQQVVSTG
                                    *** .*. : : .  :   .*  :   : ** :**::: .*. * : : *

MMAR_4222|M.marinum_M               LYSLVRHPMYVGNVILMLGIPLALGSYWGLVIVPPSVLVLAFRILDEESA
MUL_4523|M.ulcerans_Agy99           LYSLVRHPMYVGNVILMLGIPLALGSYWGLVIVPPSVLVLAFRILDEESA
MAV_1360|M.avium_104                LYRFVRHPMYTGNVIMMIGIPLALGSYWGLLFVVPGTALLALRIFDEEKL
Mb1248c|M.bovis_AF2122/97           LYKIVRHPMYAGNVVMMTGIPLALGSYWAMFILVPGTLVLVFRILDEEKL
Rv1216c|M.tuberculosis_H37Rv        LYKIVRHPMYAGNVVMMTGIPLALGSYWAMFILVPGTLVLVFRILDEEKL
MSMEG_5077|M.smegmatis_MC2_155      MYGWVRHPMYSWALVMILASPLALGSFWALLAATAGLPVLVFRILDEEKM
Mvan_4501|M.vanbaalenii_PYR-1       LYGLVRHPMYTGTVVMMLGTPLALGSLWGLLGVAASAPVLVARILDEEKM
MAB_1357c|M.abscessus_ATCC_199      LYGLVRHPMYTGSLVMMVGMPLALGSYWGLLATVPAAAALVVRIIDEEKM
TH_0548|M.thermoresistible__bu      LYGVVRHPLYAGSVVLFLGMPLALGSYWALALVVVAVAGLVVRILDEEAL
                                    :*  ****:*   :::: . ****** *.:     .   *. **:***  

MMAR_4222|M.marinum_M               LVDQLDGYRDYMQQVRYRLLPRVW
MUL_4523|M.ulcerans_Agy99           LVDQLDGYRDYMQQVRYRLLPRVW
MAV_1360|M.avium_104                LLQELPGYPDYTQKVRYRLAPHLW
Mb1248c|M.bovis_AF2122/97           LTQELSGYREYRQLVRYRLVPYVW
Rv1216c|M.tuberculosis_H37Rv        LTQELSGYREYRQLVRYRLVPYVW
MSMEG_5077|M.smegmatis_MC2_155      LVAELRGYDEYRQKIRYRLVPGVW
Mvan_4501|M.vanbaalenii_PYR-1       LTAELAGYREYRRQVRYRLVPGVW
MAB_1357c|M.abscessus_ATCC_199      LRHDLQGYDEYTEKVRSRLVPLVW
TH_0548|M.thermoresistible__bu      LRTELAGYPDYTRAVPYRLVPYVW
                                    *  :* ** :* . :  ** * :*