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M. thermoresistible (build 8) TH_0548 ()

annotation: PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN
coordinates: 1170578 - 1171246
length: 223

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0548-100% (223)PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN
M. thermoresistible (build 8)TH_2196-5e-0629.75% (121) CONSERVED HYPOTHETICAL PROTEIN

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1248c-1e-6353.18% (220) integral membrane protein
M. gilvum PYR-GCKMflv_2834-2e-0529.63% (108) hypothetical protein Mflv_2834
M. tuberculosis H37RvRv1216c-1e-6353.18% (220) integral membrane protein
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_1357c-2e-6150.93% (216) hypothetical protein MAB_1357c
M. marinum MMMAR_4222-2e-6150.91% (220) integral membrane protein
M. avium 104MAV_1360-7e-6050.91% (220) isoprenylcysteine carboxyl methyltransferase (icmt) family
M. smegmatis MC2 155MSMEG_5077-7e-5746.36% (220) integral membrane protein
M. ulcerans Agy99MUL_4523-2e-5950.00% (220) integral membrane protein
M. vanbaalenii PYR-1Mvan_4501-1e-6254.34% (219) isoprenylcysteine carboxyl methyltransferase

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_5077|M.smegmatis_MC2_155      MKLLLQAVASGVFGLAFFAVALFWPAGTFDYWQAWVFIAVFLAGTLIPSF
Mvan_4501|M.vanbaalenii_PYR-1       MKLVAQTLASSVLGAAYFVAVLFWPAGTFDYWQAWVFLAVFIVTTLGPTF
MAB_1357c|M.abscessus_ATCC_199      MKTGAQALISGLTGLAVFGAALFWPAGTFHYWQAWVFLAIFVVCSGVSSI
Mb1248c|M.bovis_AF2122/97           MHIGLKIFIWGVLGLVVFGALLFGPAGTFDYWQAWVFLAAFVSTTIGPTI
Rv1216c|M.tuberculosis_H37Rv        MHIGLKIFIWGVLGLVVFGALLFGPAGTFDYWQAWVFLAAFVSTTIGPTI
MMAR_4222|M.marinum_M               MKTVVRVALSSIVGLVAFGLIVFIPAGTFDYWQAWVFMAVFAVATLVPSI
MUL_4523|M.ulcerans_Agy99           MKTVVRVALSSIVGLVAFGLIVFIPAGTFDYWQARVFMAVFAVATLVPSI
MAV_1360|M.avium_104                MKTGLRVTATSVWGILSWILILLLPAGTLHYWQAWVFIAVFTVATIVPAA
TH_0548|M.thermoresistible__bu      --VYLRTTIYSVFGMVLFGALMFGPAGTLGYWQGWALLAVLVAFTVPYTV
Mflv_2834|M.gilvum_PYR-GCK          --------MAAIGALALYLMFVALGFG----WRSWRQYRLTGST----GF
                                              .: .   :   :    *    *:.                

MSMEG_5077|M.smegmatis_MC2_155      YLAVTDPVTLQRRLHAGPTAETRSAQKVAAVALVVAVLAVLIVSALDRRF
Mvan_4501|M.vanbaalenii_PYR-1       FLAVRHPDALARRMKAGPTAETRPAQRLIITLTVVLVTATFVLSALDHRF
MAB_1357c|M.abscessus_ATCC_199      YLARSNPAVLQRRLHGGPMAETRPVQKFAVTLLLSSFVALVVVSAFDHRF
Mb1248c|M.bovis_AF2122/97           YLARNDPAALQRRMRSGPLAEGRTIQKFIVIGAFLGFFAMMVLSACDHRY
Rv1216c|M.tuberculosis_H37Rv        YLARNDPAALQRRMRSGPLAEGRTIQKFIVIGAFLGFFAMMVLSACDHRY
MMAR_4222|M.marinum_M               YLGRTNPAALQRRMHAGPRAESRGIQKVIITAAFVALFAMVALSALDHRF
MUL_4523|M.ulcerans_Agy99           YLGRTNPAALQRRMHAGPRAESRGIQKVIITAAFVALFAMVALSALDHRF
MAV_1360|M.avium_104                YLARTNPAALQRRMRAGPRAEPRTAQKFIITGSFLSLFAAMVFSALDHRF
TH_0548|M.thermoresistible__bu      YLAVKMPDTLRRRLRSGPTAESRPAQRAAILVVQLAALGMLVLGGLDHRL
Mflv_2834|M.gilvum_PYR-GCK          HGISGRPGSPEWAAGVG------FVVAMVLGLLAPALQVFGVLAPIAAFE
                                    .     *         *                         ..      

MSMEG_5077|M.smegmatis_MC2_155      GWSSVPAWLALAADVVVVVSLVLSQVVIFQN-RFAAATIRVEAEQQVIST
Mvan_4501|M.vanbaalenii_PYR-1       GWSSAPAWVVVVGNTLVALGLSGAQLVVVQN-HYAAATVRVEAGQPLVST
MAB_1357c|M.abscessus_ATCC_199      GWSQAPTWLVIVGEVLTIGGLGMATLVVAQN-NYAAASITVESGQTVTAT
Mb1248c|M.bovis_AF2122/97           GWSSVPAAVCVIGDVLVMTGLGIAMLVVIQN-RYAASTVRVEAGQILASD
Rv1216c|M.tuberculosis_H37Rv        GWSSVPAAVCVIGDVLVMTGLGIAMLVVIQN-RYAASTVRVEAGQILASD
MMAR_4222|M.marinum_M               GWSSVPTAVCLIGDLLIATGLGIAMLVVIQN-GYAAATITVESDQKVVST
MUL_4523|M.ulcerans_Agy99           GWSSVPTAVCLIGDLLIATGLGIAMLVVIQN-GYAAATITVECDQKVVST
MAV_1360|M.avium_104                GWSSVPAWLSLLGDVLVATGLGIAMLVVIQN-SYAAATVTVEAGQTVVSS
TH_0548|M.thermoresistible__bu      GWSRAPVWVCVVGLVLTAAGLAITMGSVLQN-AWAAATVTTESDQQVVST
Mflv_2834|M.gilvum_PYR-GCK          AWG-----LQALGSVLALGGLAGTLYAQNDMGDSWRIGVDPQESTTLVRR
                                    .*.     :   .  :   .*  :     :        :  :    :   

MSMEG_5077|M.smegmatis_MC2_155      GMYGWVRHPMYSWALVMILASPLALG--SFWALLAATAGLPVLVFRILDE
Mvan_4501|M.vanbaalenii_PYR-1       GLYGLVRHPMYTGTVVMMLGTPLALG--SLWGLLGVAASAPVLVARILDE
MAB_1357c|M.abscessus_ATCC_199      GLYGLVRHPMYTGSLVMMVGMPLALG--SYWGLLATVPAAAALVVRIIDE
Mb1248c|M.bovis_AF2122/97           GLYKIVRHPMYAGNVVMMTGIPLALG--SYWAMFILVPGTLVLVFRILDE
Rv1216c|M.tuberculosis_H37Rv        GLYKIVRHPMYAGNVVMMTGIPLALG--SYWAMFILVPGTLVLVFRILDE
MMAR_4222|M.marinum_M               GLYSLVRHPMYVGNVILMLGIPLALG--SYWGLVIVPPSVLVLAFRILDE
MUL_4523|M.ulcerans_Agy99           GLYSLVRHPMYVGNVILMLGIPLALG--SYWGLVIVPPSVLVLAFRILDE
MAV_1360|M.avium_104                GLYRFVRHPMYTGNVIMMIGIPLALG--SYWGLLFVVPGTALLALRIFDE
TH_0548|M.thermoresistible__bu      GLYGVVRHPLYAGSVVLFLGMPLALG--SYWALALVVVAVAGLVVRILDE
Mflv_2834|M.gilvum_PYR-GCK          GAFAVVRNPIFTAMLSFATGVALMVPNVLALAALILLVVAIELQVRVVEE
                                    * :  **:*::   : :  . .* :      .          *  *:.:*

MSMEG_5077|M.smegmatis_MC2_155      EKMLVAELRGYDEYRQKIRYRLVPGVW-----------
Mvan_4501|M.vanbaalenii_PYR-1       EKMLTAELAGYREYRRQVRYRLVPGVW-----------
MAB_1357c|M.abscessus_ATCC_199      EKMLRHDLQGYDEYTEKVRSRLVPLVW-----------
Mb1248c|M.bovis_AF2122/97           EKLLTQELSGYREYRQLVRYRLVPYVW-----------
Rv1216c|M.tuberculosis_H37Rv        EKLLTQELSGYREYRQLVRYRLVPYVW-----------
MMAR_4222|M.marinum_M               ESALVDQLDGYRDYMQQVRYRLLPRVW-----------
MUL_4523|M.ulcerans_Agy99           ESALVDQLDGYRDYMQQVRYRLLPRVW-----------
MAV_1360|M.avium_104                EKLLLQELPGYPDYTQKVRYRLAPHLW-----------
TH_0548|M.thermoresistible__bu      EALLRTELAGYPDYTRAVPYRLVPYVW-----------
Mflv_2834|M.gilvum_PYR-GCK          PYLVHTHGDAYRSYGQAVG-RFLPVLGRFPRSVGGESR
                                       :  .  .* .* . :  *: * :