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SRPVGSDAKRLGVSQFGLLGRAFTPQQAEHIEALGFGAVWVGGSPAAELAWVEPILKVTTTLQVATGIVN IWSAAASSVAESFHRIERIYPGRFRLGIGAGHPESAKRYDKPYEALVRYLDQLDNYGVPPDRRVVAGLGP RVVGLSAQRSAGVIQYMTTPVQTFEVRKRIGPSAFVAVGQPVILTLGSNDARVAAREYLTKYLDRVNYRK NWKRLGFTDSDIGHPGSDHLIDAMVAHGSAEAVAARLHEHLDAGADHIAVQALTPIANQIPALVELAGAL GLKRA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_3778 | - | - | 100% (286) | flavin-dependent oxidoreductase |
| M. marinum M | MMAR_1084 | - | 1e-91 | 60.50% (281) | hypothetical protein MMAR_1084 |
| M. marinum M | MMAR_1083 | - | 1e-80 | 54.35% (276) | hypothetical protein MMAR_1083 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3492 | - | 3e-94 | 61.51% (278) | hypothetical protein Mb3492 |
| M. gilvum PYR-GCK | Mflv_5005 | - | 1e-91 | 59.43% (281) | hypothetical protein Mflv_5005 |
| M. tuberculosis H37Rv | Rv3463 | - | 3e-94 | 61.51% (278) | hypothetical protein Rv3463 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3778 | - | 4e-74 | 53.26% (261) | hypothetical protein MAB_3778 |
| M. avium 104 | MAV_4404 | - | 3e-97 | 64.21% (271) | hypothetical protein MAV_4404 |
| M. smegmatis MC2 155 | MSMEG_1514 | - | 2e-88 | 60.00% (270) | hypothetical protein MSMEG_1514 |
| M. thermoresistible (build 8) | TH_0027 | - | 3e-80 | 57.68% (267) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_0842 | - | 7e-92 | 60.50% (281) | hypothetical protein MUL_0842 |
| M. vanbaalenii PYR-1 | Mvan_1368 | - | 2e-93 | 61.76% (272) | hypothetical protein Mvan_1368 |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_4404|M.avium_104 ------------------MTQAAGKPDLGRFGSFGRG-VTPQQAKDIEAL
MUL_0842|M.ulcerans_Agy99 -----MPAPETDSDARSSASPAAGKPNLGRFGSFGRG-VTPAQARDIEAL
Mb3492|M.bovis_AF2122/97 -------------MTNCAAGKPSSGPNLGRFGSFGRG-VTPQQATEIEAL
Rv3463|M.tuberculosis_H37Rv -------------MTNCAAGKPSSGPNLGRFGSFGRG-VTPQQATEIEAL
Mflv_5005|M.gilvum_PYR-GCK --------------MSDVT------PDLGRFGSFGRG-VTPEQAQQIEAL
Mvan_1368|M.vanbaalenii_PYR-1 --------------MTDTK------PDLGRFGSFGRG-VTPQQAKDIEAL
MSMEG_1514|M.smegmatis_MC2_155 MTGIPREGGGVEADMTDTTPAAGPKPDLGRYGSFGRG-VTPAQAKEIEAL
MAB_3778|M.abscessus_ATCC_1997 --------------MGESK--------LNRYGVWKGGPVTPEQARTIEDL
TH_0027|M.thermoresistible__bu --------------MTDAVSL---KPDLGRFGVWTGGPIPRELAAEIEKL
MMAR_3778|M.marinum_M --------------MSRPVGSDAKRLGVSQFGLLGRA-FTPQQAEHIEAL
:.::* . .. * ** *
MAV_4404|M.avium_104 GYGAVWVGGSPPAELAWVEPLLEATTTLQVATGIVNIWTAPAGPVAESFH
MUL_0842|M.ulcerans_Agy99 GYGAVWVGGSPPAELAWVEPILAATTTLQVATGIVNIWSAPAKPVAESFH
Mb3492|M.bovis_AF2122/97 GYGAVWVGGSPPAALSWVEPILQATTTLCVATGIVNIWSAPAQRVAESFH
Rv3463|M.tuberculosis_H37Rv GYGAVWVGGSPPAALSWVEPILQATTTLCVATGIVNIWSAPAQRVAESFH
Mflv_5005|M.gilvum_PYR-GCK GYGAVWVGGSPPAELDWVEPLLAATTTLQVATGIVNIWTADAGPVAESFH
Mvan_1368|M.vanbaalenii_PYR-1 GYGAVWVGGSPPAELDWVEPLLDATTTLQVATGIVNIWTAAAGPVAESFH
MSMEG_1514|M.smegmatis_MC2_155 GYGAVWVGGSPPAELEWVEPILEATTTLQVATGIVNIWTAAPGPVAESFH
MAB_3778|M.abscessus_ATCC_1997 GYGSVWVGGVFTADLAYVEPLLAVTENLTVASGIVNIWTSPVDEIAAAFH
TH_0027|M.thermoresistible__bu GYRALWVGGSPAAELDFVEPILEATETLQVATGIVNIWTAPARTVAQSFH
MMAR_3778|M.marinum_M GFGAVWVGGSPAAELAWVEPILKVTTTLQVATGIVNIWSAAASSVAESFH
*: ::**** .* * :***:* .* .* **:******:: :* :**
MAV_4404|M.avium_104 RIEAAYPGRFLLGIGVGHPEAHTEYR---KPYDALADYLTRLDQYGVPAG
MUL_0842|M.ulcerans_Agy99 RIEAAYPGRFLLGIGVGHPEAITEYHSTGNAVDALIEYLNRLDDYGVPAN
Mb3492|M.bovis_AF2122/97 RIEAAYPGRFLLGIGVGHAEMISEYR---KPYNALVEYLDRLDDYGVPAN
Rv3463|M.tuberculosis_H37Rv RIEAAYPGRFLLGIGVGHAEMISEYR---KPYNALVEYLDRLDDYGVPAN
Mflv_5005|M.gilvum_PYR-GCK RIESAHPGRFLLGIGVGHPEAHQQYR---RPIDALVEYLDKLDEYGVPRG
Mvan_1368|M.vanbaalenii_PYR-1 RIEAAHPGRFLLGIGVGHPEAHQEYV---KPLDALTDYLDKLDEYGVPRG
MSMEG_1514|M.smegmatis_MC2_155 RIEAACPGRFLLGIGVGHREAHVEYR---KPLDALTDYLDKLDSYGVPKH
MAB_3778|M.abscessus_ATCC_1997 RIEAAYPGRFLLGVGAGHPEASAEYR---KPYDALVEYLDGLDAAGVPKE
TH_0027|M.thermoresistible__bu RIEKAYPGRFVLGLGVGHPEATEEYA---KPYEAMVTYLDVLDEATVPTS
MMAR_3778|M.marinum_M RIERIYPGRFRLGIGAGHPESAKRYD---KPYEALVRYLDQLDNYGVPPD
*** **** **:*.** * .* .. :*: ** ** **
MAV_4404|M.avium_104 RRVVAALGPRVLRLSAERSAGAHPYLTTPEHTARARELIGPSAFLAPEHK
MUL_0842|M.ulcerans_Agy99 RRVVAALGPRVLRLAARRSAGAHPYLTTPEHTGAARELIGPSAFLAPEHK
Mb3492|M.bovis_AF2122/97 RRVVAALGPRVLGLSARRSAGAHPYLTTPEHTARARELIGPSAFLAPEHK
Rv3463|M.tuberculosis_H37Rv RRVVAALGPRVLGLSARRSAGAHPYLTTPEHTARARELIGPSAFLAPEHK
Mflv_5005|M.gilvum_PYR-GCK RRVVAALGPKVLKLSADRAAGAHPYLTTPEHTARARELIGPEAFLAPEHK
Mvan_1368|M.vanbaalenii_PYR-1 RRVVAALGPKVLQLSATRAAGAHPYLTTPEHTARARELIGPEALLAPEHK
MSMEG_1514|M.smegmatis_MC2_155 RRVVAALGPKVLQLSAEHSAGAHPYLTTPEHTRSAREIIGPDAFLAPEHK
MAB_3778|M.abscessus_ATCC_1997 RRVLAALGPKVLKLSADRTAGAHPYLTTPEHTRQAREIIGPDALLVPEHK
TH_0027|M.thermoresistible__bu RRVLAALGPRMLQLAAQRSAGAHPYLTTPQHTGQARNRIGPSVFLAPEHK
MMAR_3778|M.marinum_M RRVVAGLGPRVVGLSAQRSAGVIQYMTTPVQTFEVRKRIGPSAFVAVGQP
***:*.***::: *:* ::**. *:*** :* .*: ***..::. :
MAV_4404|M.avium_104 VVLTTDAE----------HARAVGRKALDIYFNLANYRNNWKRLGFTDDE
MUL_0842|M.ulcerans_Agy99 VVLTTDAQ----------RARAVGRKALDIYLNLANYLNSWKRLGFSERD
Mb3492|M.bovis_AF2122/97 VVLTTDSA----------RARTVGRQALDMYFNLANYRNNWKRLGFTDDE
Rv3463|M.tuberculosis_H37Rv VVLTTDSA----------RARTVGRQALDMYFNLANYRNNWKRLGFTDDE
Mflv_5005|M.gilvum_PYR-GCK VVLTTDERSREEHVTDPDRAREVGRKALEIYLDLANYLNSWKRLGFSDED
Mvan_1368|M.vanbaalenii_PYR-1 VVLTTDAK----------QAREVGRKALDIYLNLANYLNNWKRLGFGDQD
MSMEG_1514|M.smegmatis_MC2_155 VVLTTDAE----------QARAVGRKALDLYLGLANYLNNFKRLGFTDDE
MAB_3778|M.abscessus_ATCC_1997 VVLSTDAP----------SAREIGRRTVDFYLTLSNYVNNWKRLGFNDED
TH_0027|M.thermoresistible__bu VVLDTDAA----------AAREIGRQTIGFYLRLRNYVNNWKQLGFTDDD
MMAR_3778|M.marinum_M VILTLGSN----------DARVAAREYLTKYLDRVNYRKNWKRLGFTDSD
*:* . ** .*. : *: ** :.:*:*** : :
MAV_4404|M.avium_104 ITRPGSDRLVDALVAYGSVDRIAARLREHLDAGADHVPVQVLTKDENLVS
MUL_0842|M.ulcerans_Agy99 IARPGSDRLVDAVVAYGTPAAIAARLNEHLQAGADHVPVQVLTKSENLVP
Mb3492|M.bovis_AF2122/97 VSRPGSDRLVDAVVAYGTPDAIAARLNEHLLAGADHVPIQVLTEDDNLVS
Rv3463|M.tuberculosis_H37Rv VSRPGSDRLVDAVVAYGTPDAIAARLNEHLLAGADHVPIQVLTEDDNLVS
Mflv_5005|M.gilvum_PYR-GCK VAKPGSDRLVDAVVAYGTAEQIAARLREHLDAGADHVPVQVLTGSDKLVP
Mvan_1368|M.vanbaalenii_PYR-1 VAKPGSDRLVDAVVAYGTVDAIAARLTEHLDAGADHVPVQVLTGSEKLVP
MSMEG_1514|M.smegmatis_MC2_155 LAKPGADRFIDAVVAYGTVDAIAARLSEHLAAGADHVPVQVLTSPDKLVP
MAB_3778|M.abscessus_ATCC_1997 LTSPGSDAFIDAVVAHGTAAEIATRLNEHLDAGADQVLIQVLGDK-GLVD
TH_0027|M.thermoresistible__bu IAEPGSDELIDAMVAHGTAEQVADALREHLDRGADHVAIQVLGGRERLLP
MMAR_3778|M.marinum_M IGHPGSDHLIDAMVAHGSAEAVAARLHEHLDAGADHIAVQALTPIANQIP
: **:* ::**:**:*: :* * *** ***:: :*.* :
MAV_4404|M.avium_104 ALAELAG--------------------PLGLKPS---------
MUL_0842|M.ulcerans_Agy99 ALAELAG--------------------PLGLAGA---------
Mb3492|M.bovis_AF2122/97 ALTELAK--------------------PLRLT-----------
Rv3463|M.tuberculosis_H37Rv ALTELAK--------------------PLRLT-----------
Mflv_5005|M.gilvum_PYR-GCK ALAELAG--------------------PLGLESTEEQR-----
Mvan_1368|M.vanbaalenii_PYR-1 ALAELAG--------------------PLGLQRKG--------
MSMEG_1514|M.smegmatis_MC2_155 ALAELAG--------------------PLGLA-----------
MAB_3778|M.abscessus_ATCC_1997 TLT--------------------------SLADALR-------
TH_0027|M.thermoresistible__bu TLXXSPRCGPNWGRCTSWSRARVWWTSPRSPRSAGRPGSGSSM
MMAR_3778|M.marinum_M ALVELAG--------------------ALGLKRA---------
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