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MQDIDQTAASPRPSRGNASPLQQMLGPLTRTGGFYARTWGTYLDRQPGELPVARPTLALAAQAFRDEIVL AGFGMLRPTPTTTTLEQTDREVLAALQMYRQHGWLDRPEAFFAAPPPLADVTVKRVHSMGRTYQRISFDS EYQPHPGEPGRERWLSYPGNRRVYGLMLQHRRPRPWLICVHGAEMGRAALDLMLFHAWHLYSDLGLNVVL PVLPLHGPRARGRPKGAAFPSENVLDAVHGAAQAVWDLRRLLSWIRSQQAGPMIGLNGISLGGLLSALVA SLDDGLTCAILGVPAVDVVDLIGRHAGISGHRRLRQTMNTAKPIGRMISPLALTPRTPQSGRFIYAGVAD RLVHPRDQVTRLWEHWGKPEIHWYQGGHTGFFGSQPVQRFVDAALVQSGLVDPAQLRRRR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_3425 | - | - | 100% (410) | hypothetical protein MMAR_3425 |
| M. marinum M | MMAR_2072 | - | e-142 | 60.77% (390) | hypothetical protein MMAR_2072 |
| M. marinum M | MMAR_0552 | - | 6e-24 | 31.33% (300) | hypothetical protein MMAR_0552 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2660c | - | 1e-148 | 61.54% (390) | hypothetical protein Mb2660c |
| M. gilvum PYR-GCK | Mflv_4981 | - | 1e-124 | 58.24% (352) | hypothetical protein Mflv_4981 |
| M. tuberculosis H37Rv | Rv2627c | - | 1e-147 | 61.28% (390) | hypothetical protein Rv2627c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4327 | - | 5e-23 | 31.30% (262) | hypothetical protein MAB_4327 |
| M. avium 104 | MAV_1605 | - | 2e-32 | 30.49% (364) | hypothetical protein MAV_1605 |
| M. smegmatis MC2 155 | MSMEG_0625 | - | 1e-19 | 28.06% (335) | hypothetical protein MSMEG_0625 |
| M. thermoresistible (build 8) | TH_1422 | - | 1e-129 | 58.20% (378) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_1215 | - | 2e-24 | 31.10% (299) | hypothetical protein MUL_1215 |
| M. vanbaalenii PYR-1 | Mvan_1418 | - | 1e-135 | 57.55% (384) | hypothetical protein Mvan_1418 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4981|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1418|M.vanbaalenii_PYR-1 ------MEKCCGASFESVAPSLRDTFRPLAKTGIYYARSWREYLAGETP-
TH_1422|M.thermoresistible__bu ------------------------VVRPFRRTGRYYGGLWREYLRRTPQE
Mb2660c|M.bovis_AF2122/97 MASSASDGTHERSAFRLSPPVLSGAMGPFMHTGLYVAQSWRDYLGQQPD-
Rv2627c|M.tuberculosis_H37Rv MASSASDGTHERSAFRLSPPVLSGAMGPFMHTGLYVAQSWRDYLGQQPD-
MMAR_3425|M.marinum_M -MQDIDQTAASPRPSRGNASPLQQMLGPLTRTGGFYARTWGTYLDRQPG-
MSMEG_0625|M.smegmatis_MC2_155 ----------------MEPSSVDPVDPPIPIPDVPGADATSRGLPRRIDL
MUL_1215|M.ulcerans_Agy99 ---------MSEISETSGTSETDPIDPPVPIPDVPGGEAGAEGLPPLSAL
MAB_4327|M.abscessus_ATCC_1997 ----------------MTAELSEHIEQPR-ITPRPAPTARPQ-LPRPGDL
MAV_1605|M.avium_104 ------------------MAKALSGLSLARDAARELAMLVPRTVAGLQES
Mflv_4981|M.gilvum_PYR-GCK ---MPIARPTVGLAVEALRDEVVLFGLRARRPLSDPASFER-IHDEVVAA
Mvan_1418|M.vanbaalenii_PYR-1 --QLPIARPTVALAAEALRDEVVLLGLRARRPLSDPEAFAR-IHDEVVAA
TH_1422|M.thermoresistible__bu -EELPLTRPTLALAAEAFRDEVVLLGLRTRRPVSDVRAFER-ITAEVREA
Mb2660c|M.bovis_AF2122/97 --KLPIARPTIALAAQAFRDEIVLLGLKARRPVSNHRVFER-ISQEVAAG
Rv2627c|M.tuberculosis_H37Rv --KLPIARPTIALAAQAFRDEIVLLGLKARRPVSNHRVFER-ISQEVAAG
MMAR_3425|M.marinum_M --ELPVARPTLALAAQAFRDEIVLAGFGMLRPTPTTTTLEQ-TDREVLAA
MSMEG_0625|M.smegmatis_MC2_155 TLRQKAIVDASAAADIALRTGVASVVAASMLPRTAATILRRRDSRIEHEH
MUL_1215|M.ulcerans_Agy99 SLRQRLVVESSAVGDIALRTYASSLLSTTVAPAVVAHALRRLDSGGERAN
MAB_4327|M.abscessus_ATCC_1997 TLRERAMVETSALTDIALRTVGALSVMGVVAP---SLVIDREFVARERDN
MAV_1605|M.avium_104 TGWAPLSPRGARQFGEVMLDELVLSAFSLLGGSPAALRPVD-ACAAAAEE
.:
Mflv_4981|M.gilvum_PYR-GCK LDFYGGRGCLADPARFFTTPDALADVEVTPVRRRNHTYAR-----LRWES
Mvan_1418|M.vanbaalenii_PYR-1 LKFYGRRGWLDDPEGFFRPPAPLTDVEVTPVRRRNHTYAR-----LRWES
TH_1422|M.thermoresistible__bu LEFFGSRGCLDDPEKFFTPPPALDEVTVLPREGRRRDHDR-----IRWDS
Mb2660c|M.bovis_AF2122/97 LEFYGNRGWLEKPSGFFAQPPPLTEVAVRKVKDRRRSFYR-----IFFDS
Rv2627c|M.tuberculosis_H37Rv LEFYGNRRWLEKPSGFFAQPPPLTEVAVRKVKDRRRSFYR-----IFFDS
MMAR_3425|M.marinum_M LQMYRQHGWLDRPEAFFAAPPPLADVTVKRVHSMGRTYQR-----ISFDS
MSMEG_0625|M.smegmatis_MC2_155 MRFYADLAEAKDPERSFPRPTEPPRVSSRPANPVAEWVAHGRVENIRFQS
MUL_1215|M.ulcerans_Agy99 LNFYAELAAEQDPRKSFPAPTELPRISARPASPLAEWIARGSVDDISFTS
MAB_4327|M.abscessus_ATCC_1997 LAFYGELAAMGDADLSFPEPEITPVVFSRPAGRVAQALAKATVENLDFES
MAV_1605|M.avium_104 LAALG-------IDGAHAAPNPLRPTSIRRRSIAGLDYER---------M
: . * :
Mflv_4981|M.gilvum_PYR-GCK GYHPLAGEPGGDRWMTYTANRRGYALMLRHPE-PRPWLMCIHGTEMGRAA
Mvan_1418|M.vanbaalenii_PYR-1 GYRPLRGEPGGDRWATYTANRRGYGLLLRHPE-PRPWLVCIHGTEMGRAA
TH_1422|M.thermoresistible__bu GYAPLPGAPGGQRYAGYSANDRCYALLLRHAE-PRPWLIGIHGTEMGRAA
Mb2660c|M.bovis_AF2122/97 GFTPHPGEPGSQRWLSYTANNREYALLLRHPE-PRPWLVCVHGTEMGRAP
Rv2627c|M.tuberculosis_H37Rv GFTPHPGEPGSQRWLSYTANNREYALLLRHPE-PRPWLVCVHGTEMGRAP
MMAR_3425|M.marinum_M EYQPHPGEPGRERWLSYPGNRRVYGLMLQHRR-PRPWLICVHGAEMGRAA
MSMEG_0625|M.smegmatis_MC2_155 SFRAV-NPALRERCRGHVRNNIVRAQHWRHNDGPHPTLCVIHG-FMGSPY
MUL_1215|M.ulcerans_Agy99 GFRAK-NPNMRQHWSALTSNNVVRAQHWRHDDGPRPTLCVIHG-FMGSSY
MAB_4327|M.abscessus_ATCC_1997 PYQTR-NPALRDYWKRFPHNSVARAQHWRHDDGPRPTLCVIHG-FFGSPY
MAV_1605|M.avium_104 AFEHDPALPATLVADGLGGPARAVVHLRRHRDGPRPWLVWVHGAGQGG-T
: :* *:* * :** *
Mflv_4981|M.gilvum_PYR-GCK LDLALFRAWYLHEELGLNVMLPVLPMHGPRGRGLP--KGAVFPGEDVLDD
Mvan_1418|M.vanbaalenii_PYR-1 LDLALFRAWYLHEELGLNVVLPVMPMHGPRGRQLP--KGAVFPGEDMLDD
TH_1422|M.thermoresistible__bu VDLAVFRARRLHRELGLNVVLPVLPMHGPRGRGLP--KGAVFPGEDVLDN
Mb2660c|M.bovis_AF2122/97 LDLAVFRAWKLHDELGLNIVMPVLPMHGPRGQGLP--KGAVFPGEDVLDD
Rv2627c|M.tuberculosis_H37Rv LDLAVFRAWKLHDELGLNIVMPVLPMHGPRGQGLP--KGAVFPGEDVLDD
MMAR_3425|M.marinum_M LDLMLFHAWHLYSDLGLNVVLPVLPLHGPRARGRP--KGAAFPSENVLDA
MSMEG_0625|M.smegmatis_MC2_155 LANGLFLSLPWFYRAGYDVLLYTLPFHGLRAERFSPFSGYGYFANGLAGF
MUL_1215|M.ulcerans_Agy99 LLNGLFFSLPWYYRSGYDVLLYTLPFHGKRAERFSPFSGFGFFASGLSGF
MAB_4327|M.abscessus_ATCC_1997 LLNGAFFALPWFFRNGYDVLLYTLPFHGRRAEKYSPFSGAGYFSHGFTGF
MAV_1605|M.avium_104 EDLLLSGIGRIHRELGFNIAMPVQPGHGCRRRQWP-----VYPDMDPLGN
. * :: : . * ** * . . : . .
Mflv_4981|M.gilvum_PYR-GCK IHATAHAVWDIRALLGWIRAENPGADIGVYGLSLGGFIAGLLAGLDDGLT
Mvan_1418|M.vanbaalenii_PYR-1 IHATGQAVWDIRALLGWIRAEQPGAAIGVYGLSLGGFIAALVASLDDELV
TH_1422|M.thermoresistible__bu VHATGQAVWDVRRLISWIRAQEPDSAIGLNGISLGGFVTSLVVSLEDGLT
Mb2660c|M.bovis_AF2122/97 VHGTAQAVWDIRRLLSWIRSQEEESLIGLNGLSLGGYIASLVASLEEGLA
Rv2627c|M.tuberculosis_H37Rv VHGTAQAVWDIRRLLSWIRSQEEESLIGLNGLSLGGYIASLVASLEEGLA
MMAR_3425|M.marinum_M VHGAAQAVWDLRRLLSWIRSQQAGPMIGLNGISLGGLLSALVASLDDGLT
MSMEG_0625|M.smegmatis_MC2_155 AEAMAQAVHDFRSVMDHLEFTG-VDRIALTGISLGGFTSALLASVDHRIQ
MUL_1215|M.ulcerans_Agy99 AESMAQAVYDFRSIVDYLHHTG-VTRIALTGISLGGYTSALVSSVENRLE
MAB_4327|M.abscessus_ATCC_1997 SESMCQAVHDFRIFVNYLRGTG-VEKIGLTGLSLGGYTTGLISTVERRID
MAV_1605|M.avium_104 VAGMMRAVSEVRAVVRWARSQA--STLVVAGISMGSPVAALVSHLERQVD
. :** :.* .: . : : *:*:*. :.*: :: :
Mflv_4981|M.gilvum_PYR-GCK CAVLGVPVADLIDLLSRHSGLGRDDPRRRTILLAAP-----LGRMISPLS
Mvan_1418|M.vanbaalenii_PYR-1 CAVLGVPVADLVDLLSRHSGMARDDPRRRTIELAGP-----LGQMISPLS
TH_1422|M.thermoresistible__bu CAILGVPVADLIELLGRHAGLRRGDPRRETMELARP-----LGRMISPLS
Mb2660c|M.bovis_AF2122/97 CAILGVPVADLIELLGRHCGLRHKDPRRHTVKMAEP-----IGRMISPLS
Rv2627c|M.tuberculosis_H37Rv CAILGVPVADLIELLGRHCGLRHKDPRRHTVKMAEP-----IGRMISPLS
MMAR_3425|M.marinum_M CAILGVPAVDVVDLIGRHAGISGHRRLRQTMNTAKP-----IGRMISPLA
MSMEG_0625|M.smegmatis_MC2_155 AVIPNVPVVTPDRTVDEWFPANMLVALERHIAHTDPELTEAAARYASPLH
MUL_1215|M.ulcerans_Agy99 AVIPNCPVVTPAELFEQWFPASKLVRLGLCLSSISRGELDAGLAFHSPLN
MAB_4327|M.abscessus_ATCC_1997 VTIPNVPVVDVKSLLHSWIPAEPTIKLAARLGHLDQGRLDGALSYSSPLT
MAV_1605|M.avium_104 AVALYTPILGLNAMIARHLQRWGPARDGFRELLQSP-VVTRLTSVIDPLA
. * . .**
Mflv_4981|M.gilvum_PYR-GCK LPPPVPMSGRFIYAGLADQVVHPREQVVRLWEHWGRPNIEWYHGGHTGFF
Mvan_1418|M.vanbaalenii_PYR-1 LTPRVPLSGRFIYAGLADQVVHPREQVARLWEHWGRPNIAWYRGGHTGFF
TH_1422|M.thermoresistible__bu LRPRVPPRGRFVYGGIADRVVHPREQVVRLWEHWDRPDIVWYRGGHTGFF
Mb2660c|M.bovis_AF2122/97 LTPLVPMPGRFIYAGIADRLVHPREQVTRLWEHWGKPEIVWYPGGHTGFF
Rv2627c|M.tuberculosis_H37Rv LTPLVPMPGRFIYAGIADRLVHPREQVTRLWEHWGKPEIVWYPGGHTGFF
MMAR_3425|M.marinum_M LTPRTPQSGRFIYAGVADRLVHPRDQVTRLWEHWGKPEIHWYQGGHTGFF
MSMEG_0625|M.smegmatis_MC2_155 YQPLVAKERRLIITGLGDRLAPP-QQAELLWEHWDRCAFHWFPGNHLLHV
MUL_1215|M.ulcerans_Agy99 YRPQLPKHRRMIIAGLGDRMAPP-DHAEPLWEHWDRCALHWFPGSHVLHV
MAB_4327|M.abscessus_ATCC_1997 YQPVVPREQRLIITGLGDRLAPP-EQSEMLWEHWDRCALHWFPGNHILHV
MAV_1605|M.avium_104 VTPAPPPERRLIVGAWHDRMAMR-EPANALQDRWAG-QLYWYDGSHVGHI
* . *:: . *::. : * ::* : *: *.* ..
Mflv_4981|M.gilvum_PYR-GCK QSRPVQHFVTDALVRSGLVTGIGRPQSPDAATG
Mvan_1418|M.vanbaalenii_PYR-1 QSRPVNRFIADALARSGLLAGIDRPGMPDATTG
TH_1422|M.thermoresistible__bu QSRSVQRFVEDALAQSGLIEAPGRA--------
Mb2660c|M.bovis_AF2122/97 QSRPVRRFVQAALEQSGLLDAPRTQRDRSA---
Rv2627c|M.tuberculosis_H37Rv QSRPVRRFVQAALEQSGLLDAPRTQRDRSA---
MMAR_3425|M.marinum_M GSQPVQRFVDAALVQSGLVDPAQLRRRR-----
MSMEG_0625|M.smegmatis_MC2_155 SQPDYLRRMTRFLRGFMFD--------------
MUL_1215|M.ulcerans_Agy99 SQLDYLRRMTAFLGDFMFD--------------
MAB_4327|M.abscessus_ATCC_1997 NQGDYLRRMTEFLDRHLNV--------------
MAV_1605|M.avium_104 FSRRVQRITDRFLRDAVLA--------------
. : *