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MAKALSGLSLARDAARELAMLVPRTVAGLQESTGWAPLSPRGARQFGEVMLDELVLSAFSLLGGSPAALR PVDACAAAAEELAALGIDGAHAAPNPLRPTSIRRRSIAGLDYERMAFEHDPALPATLVADGLGGPARAVV HLRRHRDGPRPWLVWVHGAGQGGTEDLLLSGIGRIHRELGFNIAMPVQPGHGCRRRQWPVYPDMDPLGNV AGMMRAVSEVRAVVRWARSQASTLVVAGISMGSPVAALVSHLERQVDAVALYTPILGLNAMIARHLQRWG PARDGFRELLQSPVVTRLTSVIDPLAVTPAPPPERRLIVGAWHDRMAMREPANALQDRWAGQLYWYDGSH VGHIFSRRVQRITDRFLRDAVLA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1605 | - | - | 100% (373) | hypothetical protein MAV_1605 |
| M. avium 104 | MAV_4861 | - | 6e-16 | 27.39% (387) | hypothetical protein MAV_4861 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2660c | - | 6e-29 | 31.88% (298) | hypothetical protein Mb2660c |
| M. gilvum PYR-GCK | Mflv_4331 | - | 1e-112 | 57.67% (352) | hypothetical protein Mflv_4331 |
| M. tuberculosis H37Rv | Rv2627c | - | 7e-29 | 31.88% (298) | hypothetical protein Rv2627c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4327 | - | 1e-15 | 26.18% (317) | hypothetical protein MAB_4327 |
| M. marinum M | MMAR_3425 | - | 2e-32 | 30.49% (364) | hypothetical protein MMAR_3425 |
| M. smegmatis MC2 155 | MSMEG_0625 | - | 6e-13 | 26.89% (238) | hypothetical protein MSMEG_0625 |
| M. thermoresistible (build 8) | TH_1422 | - | 1e-30 | 34.15% (287) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_1215 | - | 8e-16 | 28.87% (239) | hypothetical protein MUL_1215 |
| M. vanbaalenii PYR-1 | Mvan_2014 | - | 1e-117 | 60.23% (352) | hypothetical protein Mvan_2014 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4331|M.gilvum_PYR-GCK ---------------------MKTSERLWRIGSDFAGVLPRAHSAVAVGQ
Mvan_2014|M.vanbaalenii_PYR-1 ---------------------MRVTERIWRTGSDFAGLLPRVYAAVAADR
MAV_1605|M.avium_104 -----------------MAKALSGLSLARDAARELAMLVPRTVAGLQEST
Mb2660c|M.bovis_AF2122/97 MASSASDGTHERSAFRLSPPVLSGAMGPFMHTGLYVAQSWRDYLGQQP--
Rv2627c|M.tuberculosis_H37Rv MASSASDGTHERSAFRLSPPVLSGAMGPFMHTGLYVAQSWRDYLGQQP--
TH_1422|M.thermoresistible__bu ------------------------VVRPFRRTGRYYGGLWREYLRRTPQE
MMAR_3425|M.marinum_M MQDIDQTAASPRPS-RGNASPLQQMLGPLTRTGGFYARTWGTYLDRQP--
MSMEG_0625|M.smegmatis_MC2_155 --------MEPSSVDPVDPPIPIPDVPGADATSRGLPRRIDLTLRQKAIV
MUL_1215|M.ulcerans_Agy99 -MSEISETSGTSETDPIDPPVPIPDVPGGEAGAEGLPPLSALSLRQRLVV
MAB_4327|M.abscessus_ATCC_1997 --------MTAELSEHIEQPR-ITPRPAPTARPQ-LPRPGDLTLRERAMV
Mflv_4331|M.gilvum_PYR-GCK AWNPLSVRGLRQLGEVALDELALTGMTLTAPPPRLERSEASCAAAAAELA
Mvan_2014|M.vanbaalenii_PYR-1 DWNPLSPSGIRRFGEVALDEMALTGMTLTAPPPKLERSVDSCADAGAELS
MAV_1605|M.avium_104 GWAPLSPRGARQFGEVMLDELVLSAFSLLGGSPAALRPVDACAAAAEELA
Mb2660c|M.bovis_AF2122/97 DKLPIARPTIALAAQAFRDEIVLLGLKARRPVSNHRVFERISQEVAAGLE
Rv2627c|M.tuberculosis_H37Rv DKLPIARPTIALAAQAFRDEIVLLGLKARRPVSNHRVFERISQEVAAGLE
TH_1422|M.thermoresistible__bu EELPLTRPTLALAAEAFRDEVVLLGLRTRRPVSDVRAFERITAEVREALE
MMAR_3425|M.marinum_M GELPVARPTLALAAQAFRDEIVLAGFGMLRPTPTTTTLEQTDREVLAALQ
MSMEG_0625|M.smegmatis_MC2_155 DASAAADIALRTGVASVVAASMLPRTAATILRRRDSRIEHEHMRFYADLA
MUL_1215|M.ulcerans_Agy99 ESSAVGDIALRTYASSLLSTTVAPAVVAHALRRLDSGGERANLNFYAELA
MAB_4327|M.abscessus_ATCC_1997 ETSALTDIALRTVGALSVMGVVAP---SLVIDREFVARERDNLAFYGELA
. *
Mflv_4331|M.gilvum_PYR-GCK GLGVTGANADPD-------PVDIGSLRRRRLGRHRYEQLTFDH----DPH
Mvan_2014|M.vanbaalenii_PYR-1 SRGVAGAHADPE-------PLRVRSCRQRRFGRQAYERLRFDH----DPH
MAV_1605|M.avium_104 ALGIDGAHAAPN-------PLRPTSIRRRSIAGLDYERMAFEH----DPA
Mb2660c|M.bovis_AF2122/97 FYGNRGWLEKPSGFFAQPPPLTEVAVRKVKDRRRSFYRIFFDSGFTPHPG
Rv2627c|M.tuberculosis_H37Rv FYGNRRWLEKPSGFFAQPPPLTEVAVRKVKDRRRSFYRIFFDSGFTPHPG
TH_1422|M.thermoresistible__bu FFGSRGCLDDPEKFFTPPPALDEVTVLPREGRRRDHDRIRWDSGYAPLPG
MMAR_3425|M.marinum_M MYRQHGWLDRPEAFFAAPPPLADVTVKRVHSMGRTYQRISFDSEYQPHPG
MSMEG_0625|M.smegmatis_MC2_155 EAK-DPERSFPRPTEPPRVSSRPANPVAEWVAHGRVENIRFQSSFR-AVN
MUL_1215|M.ulcerans_Agy99 AEQ-DPRKSFPAPTELPRISARPASPLAEWIARGSVDDISFTSGFR-AKN
MAB_4327|M.abscessus_ATCC_1997 AMG-DADLSFPEPEITPVVFSRPAGRVAQALAKATVENLDFESPYQ-TRN
* : :
Mflv_4331|M.gilvum_PYR-GCK LPDTLSAEGFGGAATAVAHLCRTDSKRRPWLVWVHGAGQG-QPIDLLFSR
Mvan_2014|M.vanbaalenii_PYR-1 LPESLAA--FGGPATAVVHLCRVTDERRPWLVWVHGAGQG-QPVDLLFSR
MAV_1605|M.avium_104 LPATLVADGLGGPARAVVHLRRHRDGPRPWLVWVHGAGQG-GTEDLLLSG
Mb2660c|M.bovis_AF2122/97 EPGSQRWLSYTANNREYALLLRHP-EPRPWLVCVHGTEMGRAPLDLAVFR
Rv2627c|M.tuberculosis_H37Rv EPGSQRWLSYTANNREYALLLRHP-EPRPWLVCVHGTEMGRAPLDLAVFR
TH_1422|M.thermoresistible__bu APGGQRYAGYSANDRCYALLLRHA-EPRPWLIGIHGTEMGRAAVDLAVFR
MMAR_3425|M.marinum_M EPGRERWLSYPGNRRVYGLMLQHR-RPRPWLICVHGAEMGRAALDLMLFH
MSMEG_0625|M.smegmatis_MC2_155 PALRERCRGHVRNNIVRAQHWRHNDGPHPTLCVIHG-FMGSPYLANGLFL
MUL_1215|M.ulcerans_Agy99 PNMRQHWSALTSNNVVRAQHWRHDDGPRPTLCVIHG-FMGSSYLLNGLFF
MAB_4327|M.abscessus_ATCC_1997 PALRDYWKRFPHNSVARAQHWRHDDGPRPTLCVIHG-FFGSPYLLNGAFF
: :* * :** *
Mflv_4331|M.gilvum_PYR-GCK ARRIQDELGVNVALPVQPGCGVRASAWP-----EYPTMDPLANVAGMLRV
Mvan_2014|M.vanbaalenii_PYR-1 ARRLQEELGFNVALPVQPGCGVRRGRWP-----EYPSMDPLANVAGMMRA
MAV_1605|M.avium_104 IGRIHRELGFNIAMPVQPGHGCRRRQWP-----VYPDMDPLGNVAGMMRA
Mb2660c|M.bovis_AF2122/97 AWKLHDELGLNIVMPVLPMHGPRGQGLPKGA--VFPGEDVLDDVHGTAQA
Rv2627c|M.tuberculosis_H37Rv AWKLHDELGLNIVMPVLPMHGPRGQGLPKGA--VFPGEDVLDDVHGTAQA
TH_1422|M.thermoresistible__bu ARRLHRELGLNVVLPVLPMHGPRGRGLPKGA--VFPGEDVLDNVHATGQA
MMAR_3425|M.marinum_M AWHLYSDLGLNVVLPVLPLHGPRARGRPKGA--AFPSENVLDAVHGAAQA
MSMEG_0625|M.smegmatis_MC2_155 SLPWFYRAGYDVLLYTLPFHGLRAERFSPFSGYGYFANGLAGFAEAMAQA
MUL_1215|M.ulcerans_Agy99 SLPWYYRSGYDVLLYTLPFHGKRAERFSPFSGFGFFASGLSGFAESMAQA
MAB_4327|M.abscessus_ATCC_1997 ALPWFFRNGYDVLLYTLPFHGRRAEKYSPFSGAGYFSHGFTGFSESMCQA
* :: : . * * * . : . . :.
Mflv_4331|M.gilvum_PYR-GCK VSEVRALVRWLRPQATA--IAVAGVSMGSPVAGLVSHLEP-VDAVAVYTP
Mvan_2014|M.vanbaalenii_PYR-1 VSEVRALVRWLRPQAAS--IAVAGVSMGSPVAGLVSHLEP-VDAVAVYTP
MAV_1605|M.avium_104 VSEVRAVVRWARSQAST--LVVAGISMGSPVAALVSHLERQVDAVALYTP
Mb2660c|M.bovis_AF2122/97 VWDIRRLLSWIRSQEEESLIGLNGLSLGGYIASLVASLEEGLACAILGVP
Rv2627c|M.tuberculosis_H37Rv VWDIRRLLSWIRSQEEESLIGLNGLSLGGYIASLVASLEEGLACAILGVP
TH_1422|M.thermoresistible__bu VWDVRRLISWIRAQEPDSAIGLNGISLGGFVTSLVVSLEDGLTCAILGVP
MMAR_3425|M.marinum_M VWDLRRLLSWIRSQQAGPMIGLNGISLGGLLSALVASLDDGLTCAILGVP
MSMEG_0625|M.smegmatis_MC2_155 VHDFRSVMDHLEFTGVDR-IALTGISLGGFTSALLASVDHRIQAVIPNVP
MUL_1215|M.ulcerans_Agy99 VYDFRSIVDYLHHTGVTR-IALTGISLGGYTSALVSSVENRLEAVIPNCP
MAB_4327|M.abscessus_ATCC_1997 VHDFRIFVNYLRGTGVEK-IGLTGLSLGGYTTGLISTVERRIDVTIPNVP
* :.* .: . : : *:*:*. :.*: :: : . *
Mflv_4331|M.gilvum_PYR-GCK IFGLNAMIAAHLGRWGPSVDDTVA-LLRSEVVEQVSAAVDYQAVEPSASP
Mvan_2014|M.vanbaalenii_PYR-1 ISGLNAMIAAHLGRWGPSVGETVA-LLRSQAVERVASAVDYHSVAPSAPP
MAV_1605|M.avium_104 ILGLNAMIARHLQRWGPARDGFRE-LLQSPVVTRLTSVIDPLAVTPAPPP
Mb2660c|M.bovis_AF2122/97 VADLIELLGRHCG----LRHKDPR-RHTVKMAEPIGRMISPLSLTPLVPM
Rv2627c|M.tuberculosis_H37Rv VADLIELLGRHCG----LRHKDPR-RHTVKMAEPIGRMISPLSLTPLVPM
TH_1422|M.thermoresistible__bu VADLIELLGRHAG----LRRGDPR-RETMELARPLGRMISPLSLRPRVPP
MMAR_3425|M.marinum_M AVDVVDLIGRHAG----ISGHRRL-RQTMNTAKPIGRMISPLALTPRTPQ
MSMEG_0625|M.smegmatis_MC2_155 VVTPDRTVDEWFPANMLVALERHIAHTDPELTEAAARYASPLHYQPLVAK
MUL_1215|M.ulcerans_Agy99 VVTPAELFEQWFPASKLVRLGLCLSSISRGELDAGLAFHSPLNYRPQLPK
MAB_4327|M.abscessus_ATCC_1997 VVDVKSLLHSWIPAEPTIKLAARLGHLDQGRLDGALSYSSPLTYQPVVPR
. . * .
Mflv_4331|M.gilvum_PYR-GCK DRRLIVGAWHDRMAM-REPAQVLHARWGG-ELYWHQGSHVGHLFAPGVHT
Mvan_2014|M.vanbaalenii_PYR-1 ERRLIVGAWHDRMAR-REPALALHDRWGG-RLYWHRGSHVGHLFAGGVQD
MAV_1605|M.avium_104 ERRLIVGAWHDRMAM-REPANALQDRWAG-QLYWYDGSHVGHIFSRRVQR
Mb2660c|M.bovis_AF2122/97 PGRFIYAGIADRLVHPREQVTRLWEHWGKPEIVWYPGGHTGFFQSRPVRR
Rv2627c|M.tuberculosis_H37Rv PGRFIYAGIADRLVHPREQVTRLWEHWGKPEIVWYPGGHTGFFQSRPVRR
TH_1422|M.thermoresistible__bu RGRFVYGGIADRVVHPREQVVRLWEHWDRPDIVWYRGGHTGFFQSRSVQR
MMAR_3425|M.marinum_M SGRFIYAGVADRLVHPRDQVTRLWEHWGKPEIHWYQGGHTGFFGSQPVQR
MSMEG_0625|M.smegmatis_MC2_155 ERRLIITGLGDRLAP-PQQAELLWEHWDRCAFHWFPGNHLLHVSQPDYLR
MUL_1215|M.ulcerans_Agy99 HRRMIIAGLGDRMAP-PDHAEPLWEHWDRCALHWFPGSHVLHVSQLDYLR
MAB_4327|M.abscessus_ATCC_1997 EQRLIITGLGDRLAP-PEQSEMLWEHWDRCALHWFPGNHILHVNQGDYLR
*:: . **:. : * :* : *. *.* ..
Mflv_4331|M.gilvum_PYR-GCK ASEKFLRSLTG------------
Mvan_2014|M.vanbaalenii_PYR-1 ASEEFLRSVAADRP---------
MAV_1605|M.avium_104 ITDRFLRDAVLA-----------
Mb2660c|M.bovis_AF2122/97 FVQAALEQSGLLDAPRTQRDRSA
Rv2627c|M.tuberculosis_H37Rv FVQAALEQSGLLDAPRTQRDRSA
TH_1422|M.thermoresistible__bu FVEDALAQSGLIEAPGRA-----
MMAR_3425|M.marinum_M FVDAALVQSGLVDPAQLRRRR--
MSMEG_0625|M.smegmatis_MC2_155 RMTRFLRGFMFD-----------
MUL_1215|M.ulcerans_Agy99 RMTAFLGDFMFD-----------
MAB_4327|M.abscessus_ATCC_1997 RMTEFLDRHLNV-----------
*