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QLRYIGIPLLIAEAGGDPWAIDQSLQAGRPAQISDLGAAFHAAGRCTAEADAAFDQARRRFEEAWNRQNS ERPINDSAEVQRVAQSLGAQSLELPKIGVDLENIAAALAEVQRSSSGKIAGLEGQLRQLDDEIGQAVMLE RNHQLTAEDKAALDAFMHACEDDAIRDTQAALAELNSIRDGYSNFLRTAEKSLAVDGLDPARIWGADNHE PESAEQAEQDVHDALAGDQGAAGRVNAVLGSITPDQLAGKVPLTAEQASVLSQLQAQEHGMSVGALTATE QRLGAQRAMIADSWQLMSNPNISFPKTPLTVGAKQGSDTVKGGVTQLPESVQQALNSPGVLFTHQMNDIA GVVKDGDRGFQTNTELDRAMIHKASVMMDTPIWHADPASQGQDVERDPALDPAVSNVLSAVSPDHQVVHD TITGADHDKFLKNITHHYWKDNGQGVGSLFSWTGDPAVVQGPEEGIAADTAHAYSSYIGGYQQELLHLPG NHTLGQVNPNLVRDMAHGLGPYVNNIAETSGGLPGFGKPLDSETLSGALPVAKGVFSVLSSDNEAAQYFN GQAYAQAVLHEGAFAADPTHSGYNQHLYDAATLRALVDVGTHNAFQANEDNGYHQGVSEYQSKKSAYETG LQGLTAAGGFVPGVGRIAGPTIGVLGQNLENGILGPAPTAPTENPIQPMSLGMTDQEILNAMLGTGHTVT GLPPGYIVYDDDHPNGRIATLEELEPQGVTPGQYSNVIGPALSQSLEPRPPSESLSPDAALVSRYDDIVG VPHPDQGRK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_3061 | - | - | 100% (780) | hypothetical protein MMAR_3061 |
| M. marinum M | MMAR_1534 | - | 0.0 | 49.44% (799) | hypothetical protein MMAR_1534 |
| M. marinum M | MMAR_5468 | - | 5e-66 | 59.09% (220) | hypothetical protein MMAR_5468 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2105 | - | 1e-68 | 59.01% (222) | hypothetical protein Mb2105 |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv2079 | - | 3e-67 | 58.56% (222) | hypothetical protein Rv2079 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1285c | - | 1e-67 | 35.39% (568) | hypothetical protein MAB_1285c |
| M. avium 104 | MAV_0031 | - | 9e-62 | 54.50% (222) | hypothetical protein MAV_0031 |
| M. smegmatis MC2 155 | MSMEG_5089 | - | 8e-93 | 37.46% (582) | hypothetical protein MSMEG_5089 |
| M. thermoresistible (build 8) | TH_3653 | - | 2e-15 | 45.35% (86) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_2305 | - | 0.0 | 95.48% (753) | hypothetical protein MUL_2305 |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3061|M.marinum_M MQLRYIGIPLLIAEAGGDPWAIDQSLQAGRPAQISDLGAAFHAAGRCTAE
MUL_2305|M.ulcerans_Agy99 ---------------MGD----RSKPPSGSPGADFGPGGAFHAAGRCTAE
TH_3653|M.thermoresistible__bu --------------------------------------------------
Mb2105|M.bovis_AF2122/97 MQLRHINIRALIAEAGGDPWAIEHSLHAGRPAQIAELAEAFHAAGRCTAE
Rv2079|M.tuberculosis_H37Rv MQLRHINIRALIAEAGGDPWAIEHSLHAGRPAQIAELAEAFHAAGRYTAE
MSMEG_5089|M.smegmatis_MC2_155 --------MGALDGFYSTWNKARETFGQGAPTDGSQFDQSRSLTQMKASV
MAV_0031|M.avium_104 MGLPYIDKQALIAEAGGDPWAINASLQAGSPSQISNLAGAFHRAGRCTQE
MAB_1285c|M.abscessus_ATCC_199 ---------------------MGMTLAELQEWPPHIKALADAASKRGDAS
MMAR_3061|M.marinum_M ADAAFDQARRRFEEAWNRQNSERPINDSAEVQRVAQSLGAQSLELP-KIG
MUL_2305|M.ulcerans_Agy99 ADAAFDQARRRFEEAWNRQNGEHPINDSAEVQRVAQSLGAQSLELP-KIG
TH_3653|M.thermoresistible__bu --------------------------------------------------
Mb2105|M.bovis_AF2122/97 ANAAFEEARRRFEASWNRENGEHPINDSAEVQRVTAALGVQSLQLP-KIG
Rv2079|M.tuberculosis_H37Rv ANAAFEEARRRFEASWNRENGEHPINDSAEVQRVTAALGVQSLQLP-KIG
MSMEG_5089|M.smegmatis_MC2_155 EAAAPDDRWQGSGANAYAAANKEHAQVYQKLADLDQKMAAEVKNAANVVS
MAV_0031|M.avium_104 ADNAFQQARSRFDAAWNHQDGDHPINDSEEVQRVTKALGAQSLQLP-KIG
MAB_1285c|M.abscessus_ATCC_199 QQAADKVQAIVDMSTWQGDAGEAARDAMKRSAARFDNAGFEALYVAMHAN
MMAR_3061|M.marinum_M VDLENIAAALAEVQRSSSGKIAGLEGQLRQLDDEIGQAVMLERNHQLTAE
MUL_2305|M.ulcerans_Agy99 VDLENIAAALAEVQRSSSGKIAGLEGQLRQLDDEIGQAVMLERNHQLTAE
TH_3653|M.thermoresistible__bu --------------------------------------------------
Mb2105|M.bovis_AF2122/97 VDLENIAADLAEAQRAAAGRIATLESQLQRIDDQLDQALELEHDPRLAAA
Rv2079|M.tuberculosis_H37Rv VDLENIAADLAEAQRAAAGRIATLESQLQRIDDQLDQALELEHDPRLAAA
MSMEG_5089|M.smegmatis_MC2_155 AGRTNLDNAKSWVEGMANSLPATSQQDRERKLIPIAREGINRVDNIVKSA
MAV_0031|M.avium_104 ADLEGIAAALAEAQKAGAARIATLDAQLKNISDLVVEAVALLNDKSLSPP
MAB_1285c|M.abscessus_ATCC_199 KAYGESQTLADDIGAFLAYAAAPPKVDINPKTNAVTPPDISGLNKEQLQK
MMAR_3061|M.marinum_M DKAALDAFMHACEDDAIRDTQAALAELNSIRDGYSNFLRTAEKSLAVDGL
MUL_2305|M.ulcerans_Agy99 DKAALDAFMHACEDDAIRDTQAALAELNSIRDGYSNFLRTAEKSLAVDGF
TH_3653|M.thermoresistible__bu --------------------------------------------------
Mb2105|M.bovis_AF2122/97 ERSELDALITCLEQDAIDDTASALGQLQSIRAGYSDHLQQSLAMLRADGY
Rv2079|M.tuberculosis_H37Rv ERSELDALITCLEQDAIDDTASALGQLQSIRAGYSDHLQQSLAMLRADGY
MSMEG_5089|M.smegmatis_MC2_155 TADMMGIKGNVEKLRGEYDTIKTTMRFGPESEKKPGDKKDDAQMLGNEEK
MAV_0031|M.avium_104 DRDALHALINTCENDALRDTKAALADLQAIRNGYADGLQKSLNSLHAEGY
MAB_1285c|M.abscessus_ATCC_199 VIDKLKDLQQRVTGLVARGEMLDDSLARVLDEGTGGHTMAQKQIAEG---
MMAR_3061|M.marinum_M DPARIWGADNHEPESAEQAEQDVHDAL-AGDQGAAGRVNAVLG--SITPD
MUL_2305|M.ulcerans_Agy99 DPARIWGADNHEPESAEQAEQDVHDAL-AGDQGAAGRVNAVLG--SITPD
TH_3653|M.thermoresistible__bu --------------------------------------------------
Mb2105|M.bovis_AF2122/97 DGAGLQGLDAPQSPVKLEEPIQIPPPG-TGAPEVHRWWTSLTS--EERQR
Rv2079|M.tuberculosis_H37Rv DGAGLQGLDAPQSPVKPEEPIQIPPPG-TGAPEVHRWWTSLTS--EERQR
MSMEG_5089|M.smegmatis_MC2_155 DDDGIP--EMHAPSTEDQARMDVEQVLSEGDGGAAERVDEVLS--SIKP-
MAV_0031|M.avium_104 DGAPLHGVDADGVAPASPAQQAALDDIRRATN------QAVLD--QMAKV
MAB_1285c|M.abscessus_ATCC_199 -----------TPEQAERDVHDVLAGTATEEQKARVQAASILSPEQIADR
MMAR_3061|M.marinum_M QLAGKVPLTAEQASVLSQLQAQEHGMSVGALTATEQRLGAQRAMIADSWQ
MUL_2305|M.ulcerans_Agy99 QLAGKVPLTAEQASVLSQLQAQEHGMSVEALAAAEQRLGAQRGMIADSWQ
TH_3653|M.thermoresistible__bu --------------------------------------------------
Mb2105|M.bovis_AF2122/97 LIAEHPEQIGNLNGVPVSARSDAN---IAVMTRDLNRVRDIATRYRTSVD
Rv2079|M.tuberculosis_H37Rv LIAEHPEQIGNLNGVPVSARSDAN---IAVMTRDLNRVRDIATRYRTSVD
MSMEG_5089|M.smegmatis_MC2_155 ----GDELTPQQDAYLSEMQRQQKGMSVEDLRAAEQRLGDHKNVIADSWQ
MAV_0031|M.avium_104 RAAQRALDKAMADVYAHGPGSPEGEAASAQLPKLKADLAHALDDLGKIPD
MAB_1285c|M.abscessus_ATCC_199 DAGRPVQLTRPQQQVLGQLQAQMNGMSVEDIHRAEQRLGNNKSIIGNALQ
MMAR_3061|M.marinum_M LMSNPNISFPKTPLTVG---AKQGSDTVKGGVTQLPESVQQALNSPGVLF
MUL_2305|M.ulcerans_Agy99 LMSNPNMSFPKTPLTVG---AKQGSDTVKGGVTQLPESVQQALNSPGALF
TH_3653|M.thermoresistible__bu --------------------------------------------------
Mb2105|M.bovis_AF2122/97 DVLGDPAKYGLSAGDIT---RYRNADETKKGLDHN-ARNDPRNPSPVYLF
Rv2079|M.tuberculosis_H37Rv DVLGDPAKYGLSAGDIT---RYRNADETKKGLDHN-ARNDPRNPSPVYLF
MSMEG_5089|M.smegmatis_MC2_155 LMSNDDVEYSAGAGDDKKGAASQLPDSVQKALTNAGDTWPIGDGIGQLRY
MAV_0031|M.avium_104 YTGIDPASVNVTPDGHFMFTYNVNGQPVQVVGQLQNGTGEFFDQATGTYY
MAB_1285c|M.abscessus_ATCC_199 MMGSNQYGYAKTELRPGAQGSTTELTTGGYDKLPTSVQEALNDKSPGFSY
MMAR_3061|M.marinum_M THQ-----------------MNDIAGVVKDGDRGFQTNTELDRAMIHKAS
MUL_2305|M.ulcerans_Agy99 THQ-----------------MNDIAGIVKDGDKGFQPNTELDRAMIHKAS
TH_3653|M.thermoresistible__bu --------------------MKDISAIVRDGDPELQTGTQVDRHMIDKAD
Mb2105|M.bovis_AF2122/97 AYD-----------------PMAFGGKGRAAIAIGNPDTAKHTAVIVPGT
Rv2079|M.tuberculosis_H37Rv AYD-----------------PMAFGGKGRAAIAIGNPDTAKHTAVIVPGT
MSMEG_5089|M.smegmatis_MC2_155 EGD-----------------LKAISEIVKDGNPGFQTGTELDRQLIVAAD
MAV_0031|M.avium_104 TFN-----------------GGKLTGMRTPDPGKVEATSEPLWTAITTAV
MAB_1285c|M.abscessus_ATCC_199 VSQGPGQGTAPITQGSTLGNLDRLSDVIKDGDPGFQNGTELDRRLMQRGA
: : : : .
MMAR_3061|M.marinum_M VMMDTPIWHADPASQGQDVE-RDPALDPAVSNVLSAVSPDHQVVHDTITG
MUL_2305|M.ulcerans_Agy99 VMMDTPIWHADPASQGQDVE-RDPVLDPAVSNVLSAVSPDHQVVHDTITG
TH_3653|M.thermoresistible__bu RMMDAPIWEKDPASNGGSLDQRDPYLDGVVSDIFTSAGRDHIAVGEHLLS
Mb2105|M.bovis_AF2122/97 SSSVKGGWLHDNHDDALNLFNQAKAADPNNPTAVIAWMG-YDAPNDFTDP
Rv2079|M.tuberculosis_H37Rv SSSVKGGWLHDNHDDALNLFNQAKAADPNNPTAVIAWMG-YDAPNDFTDP
MSMEG_5089|M.smegmatis_MC2_155 KAMDARDIPGGQILGR----------ESTVQSLFEAVDDDHQIINDHLMG
MAV_0031|M.avium_104 GGYGLKVGGTAAWQGLKTLFSREMLDGLTSENVMSRAMTGAEVRAALAEA
MAB_1285c|M.abscessus_ATCC_199 DILHFENQNHDSHEGAA---------DSTIQNIFSSAGRDHIVDHDMMVN
.
MMAR_3061|M.marinum_M A---DHDKFLKNITHHYWKDNGQGVGSLFSWTGDPAVV----QGPEEGIA
MUL_2305|M.ulcerans_Agy99 A---DHDKFLENITHHYWKDNGQGVGSLFSWTGDPAVV----QGPQEGIA
TH_3653|M.thermoresistible__bu E---KGDDFQG---------------------------------------
Mb2105|M.bovis_AF2122/97 R---IATPMLARIGGAALAEDVNGLWVTHLGVGQNVTV----LGHSYGST
Rv2079|M.tuberculosis_H37Rv R---IATPMLARIGGAALAEDVNGLWVTHLGVGQNVTV----LGHSYGST
MSMEG_5089|M.smegmatis_MC2_155 RNGVDVDDFLRDVNTTDWPDNGKAAGYLFSWTNEASS------GPEAHIA
MAV_0031|M.avium_104 E-------YPRGIGGE----------------------------PVPSTH
MAB_1285c|M.abscessus_ATCC_199 PEGKRNDQFLGDLTHHQFTDGGKAAGSLMSWTHDSAHVGPGVSADQAKLS
MMAR_3061|M.marinum_M ADTAHAYSSYIGGYQQELLHLPGN--------HTLGQVNPNLVRDMAHGL
MUL_2305|M.ulcerans_Agy99 ADTAHAYSSYIGNNQQELLHLPGN--------HTLGQVNPNLVRDMAHGL
TH_3653|M.thermoresistible__bu ---------------VEVQAMP----------------------------
Mb2105|M.bovis_AF2122/97 TVADAFALGGMHANDAVLLGCPGT--------DLAHSAASFHLDGGRVYV
Rv2079|M.tuberculosis_H37Rv TVADAFALGGMHANDAVLLGCPGT--------DLAHSAASFHLDGGRVYV
MSMEG_5089|M.smegmatis_MC2_155 AEVADKYAGYIGEHRTDLMNFDG---------QTLGQRNPELVQQYAHGL
MAV_0031|M.avium_104 PLEPPPVEHTPPPADAPVEHAPGG--------PHVAVPDSPPPLPPEQPP
MAB_1285c|M.abscessus_ATCC_199 GETAHAYASYVADHKELNALPANDNQGLGQGTKTLGQLSPELVKGMAWGL
MMAR_3061|M.marinum_M GPYVNNIAETS----GGLPGFG--KPLDSETLSGALPVAKGVFSVLSSDN
MUL_2305|M.ulcerans_Agy99 GPYVNNIAETS----GGLPGFG--DPLDGKTLSGALPVAKGVFSVLSSDN
TH_3653|M.thermoresistible__bu PRWITHDPEGR----VRILSYG--EVHD-------LPCAT----------
Mb2105|M.bovis_AF2122/97 GAASTDPISML----GQLDSLS--QYVNRGNLAGQLQGLAVG--------
Rv2079|M.tuberculosis_H37Rv GAASTDPISML----GQLDSLS--QYVNRGNLAGQLQGLAVG--------
MSMEG_5089|M.smegmatis_MC2_155 VPFVDDMAGNN----GSGGEFE--IDTEKDRRAGLMPNAKGVFSVLNTDP
MAV_0031|M.avium_104 PPPLASDHPLF----EGYHPID--PGPEFTNADGSLRYPDDT--------
MAB_1285c|M.abscessus_ATCC_199 APYTAAIGGGDPAIFGSTPGFDNALDTDDAIGNGSMPQAKALFKVLSTNA
: :
MMAR_3061|M.marinum_M EAAQYFNGQAYAQAVLHEGAFAADPTHSGYNQH--LYDAATLRALVDVGT
MUL_2305|M.ulcerans_Agy99 EAAQYFNGQAYAQAVLHEGAFAADPTHSGYNQH--LYDAATLRALVDVGA
TH_3653|M.thermoresistible__bu ------------------------PSFSEYNRT--LAEAT----------
Mb2105|M.bovis_AF2122/97 --------------------LGTDPAGDGFGSV--RFRAEVPNS------
Rv2079|M.tuberculosis_H37Rv --------------------LGTDPAGDGFGSV--RFRAEVPNS------
MSMEG_5089|M.smegmatis_MC2_155 TAATTINSAAISQAMIAETAFAENPNDPLAHSY--LSSAATLRGLVDVGA
MAV_0031|M.avium_104 ---------------------LPTKPYAVPGTV--VPDAQLSAG------
MAB_1285c|M.abscessus_ATCC_199 EAATTLGGALYGDSVMATNHYAEAVKHSGVGEIGDLDQAGRFRGLADAG-
*
MMAR_3061|M.marinum_M HNAFQANEDNGYHQGVSEYQSKKSAYETGLQGLTAAGGFVPGVGRIAGPT
MUL_2305|M.ulcerans_Agy99 HNGFQANEDNGYHQDVSEYQSKKSAYETGLQGLTAAGGFVPGVGRIAGPT
TH_3653|M.thermoresistible__bu --------EQTLGQGSSEHMKSAPTYRY----------------------
Mb2105|M.bovis_AF2122/97 -DGINPHDHSYYYHRGSEALRSMADIASGHGDALASDGMLAQPRHQPG--
Rv2079|M.tuberculosis_H37Rv -DGINPHDHSYYYHRGSEALRSMADIASGHGDALASDGMLAQPRHQPG--
MSMEG_5089|M.smegmatis_MC2_155 HEAFQAFNENGYNAGVDETTWKKAGFDAAVTAFSTGSTFVPGVGVVASPV
MAV_0031|M.avium_104 ----TVLSRFGFPGGGYLAPEGTPFAELALPPGSAGKPYFQYVVDDPTR-
MAB_1285c|M.abscessus_ATCC_199 --LAAGNDAQHKADTVSKEQYAKDLQRLKETAYGAITKILPIPAEAATPF
MMAR_3061|M.marinum_M IGVLGQNLENGI-LGPAPTAPTENPIQPMSLGMTDQEILNAMLGTGHTVT
MUL_2305|M.ulcerans_Agy99 IGVLGQNLENGI-LGPAPTAPTENPIQPMSLGMADQEILNAMLGTGHTVT
TH_3653|M.thermoresistible__bu --------------------------------------------------
Mb2105|M.bovis_AF2122/97 --------------------------------------------------
Rv2079|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_5089|M.smegmatis_MC2_155 ISQVGSIFSNEF-FE-NPPGPVERPLPQLSEPVATTTLLNAMLAAN----
MAV_0031|M.avium_104 --------------------------------------------------
MAB_1285c|M.abscessus_ATCC_199 GIMSDALKDSIVGKAPEPGQPANTTVPNLNPAYGQQQLLNAYAATGVLRP
MMAR_3061|M.marinum_M GLPPGYIVYDDDHPNGRIATLEELEPQGVTPGQYSNVIGPALSQS---LE
MUL_2305|M.ulcerans_Agy99 GLPPGYILYDDDHPNGRIATLEELEPQGVTPGQYSNVIGPALSQS---LE
TH_3653|M.thermoresistible__bu -------------------------------NQVSEVMNPQTDQ------
Mb2105|M.bovis_AF2122/97 ---------------------VEIDIPGLGSVEIDIPGTPASIDP---EW
Rv2079|M.tuberculosis_H37Rv ---------------------VEIDIPGLGSVEIDIPGTPASIDP---EW
MSMEG_5089|M.smegmatis_MC2_155 --------QPLDLPPGYVVGNEVVQPPGVSDHEFAATLNAEIGRQTVTVD
MAV_0031|M.avium_104 ----------------------LPPGWHIEQSEVAPWFHQPGGGQ---QY
MAB_1285c|M.abscessus_ATCC_199 EQFPPNMLVPDPKHPGVMRVGTLEELRQMKGPDDRPVYEHLTSDKYHTMV
:
MMAR_3061|M.marinum_M PRPPSESLSPDAALVSRYDDIVGVPHPDQGRK-
MUL_2305|M.ulcerans_Agy99 PRPPSESLSPDAALVSRYDDIVGVPHPDQGRK-
TH_3653|M.thermoresistible__bu PEPP-----------------------------
Mb2105|M.bovis_AF2122/97 SRPPGSITDDHVFDAPLHR--------------
Rv2079|M.tuberculosis_H37Rv SRPPGSITDDHVFDAPLHR--------------
MSMEG_5089|M.smegmatis_MC2_155 GDGPDEIYADQYNLIIQDPDIQAPPTATRSENK
MAV_0031|M.avium_104 RIINEEGATGDVAELVRWGYLRRIN--------
MAB_1285c|M.abscessus_ATCC_199 NEALRRIPGDAGSAQPLIDAYNNAVKTTE----