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GMTLAELQEWPPHIKALADAASKRGDASQQAADKVQAIVDMSTWQGDAGEAARDAMKRSAARFDNAGFEA LYVAMHANKAYGESQTLADDIGAFLAYAAAPPKVDINPKTNAVTPPDISGLNKEQLQKVIDKLKDLQQRV TGLVARGEMLDDSLARVLDEGTGGHTMAQKQIAEGTPEQAERDVHDVLAGTATEEQKARVQAASILSPEQ IADRDAGRPVQLTRPQQQVLGQLQAQMNGMSVEDIHRAEQRLGNNKSIIGNALQMMGSNQYGYAKTELRP GAQGSTTELTTGGYDKLPTSVQEALNDKSPGFSYVSQGPGQGTAPITQGSTLGNLDRLSDVIKDGDPGFQ NGTELDRRLMQRGADILHFENQNHDSHEGAADSTIQNIFSSAGRDHIVDHDMMVNPEGKRNDQFLGDLTH HQFTDGGKAAGSLMSWTHDSAHVGPGVSADQAKLSGETAHAYASYVADHKELNALPANDNQGLGQGTKTL GQLSPELVKGMAWGLAPYTAAIGGGDPAIFGSTPGFDNALDTDDAIGNGSMPQAKALFKVLSTNAEAATT LGGALYGDSVMATNHYAEAVKHSGVGEIGDLDQAGRFRGLADAGLAAGNDAQHKADTVSKEQYAKDLQRL KETAYGAITKILPIPAEAATPFGIMSDALKDSIVGKAPEPGQPANTTVPNLNPAYGQQQLLNAYAATGVL RPEQFPPNMLVPDPKHPGVMRVGTLEELRQMKGPDDRPVYEHLTSDKYHTMVNEALRRIPGDAGSAQPLI DAYNNAVKTTE*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_1285c | - | - | 100% (782) | hypothetical protein MAB_1285c |
| M. abscessus ATCC 19977 | MAB_0243 | - | 7e-17 | 30.19% (159) | hypothetical protein MAB_0243 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2820c | - | 2e-08 | 26.92% (208) | hypothetical protein Mb2820c |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv2797c | - | 2e-08 | 26.92% (208) | hypothetical protein Rv2797c |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_1534 | - | 6e-75 | 32.90% (693) | hypothetical protein MMAR_1534 |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_5089 | - | 5e-49 | 30.52% (557) | hypothetical protein MSMEG_5089 |
| M. thermoresistible (build 8) | TH_3653 | - | 5e-06 | 28.41% (88) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_2305 | - | 2e-68 | 35.16% (566) | hypothetical protein MUL_2305 |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1534|M.marinum_M MQLRYISVPALVAYAGGDPWAINQSLQAGRPAQISDLATAFHAAGRSTAE
MUL_2305|M.ulcerans_Agy99 ---------------MGD----RSKPPSGSPGADFGPGGAFHAAGRCTAE
Mb2820c|M.bovis_AF2122/97 -----------MPLTVADIDRWNAQAVREVFHAASARAEVTFEASRQLAA
Rv2797c|M.tuberculosis_H37Rv -----------MPLTVADIDRWNAQAVREVFHAASARAEVTFEASRQLAA
TH_3653|M.thermoresistible__bu --------------------------------------------------
MSMEG_5089|M.smegmatis_MC2_155 -------------MGALDGFYSTWNKARETFGQGAPTDGSQFDQSRSLTQ
MAB_1285c|M.abscessus_ATCC_199 -------------MGMTLAELQEWPPHIKALADAASKRGDASQQAADKVQ
MMAR_1534|M.marinum_M SNITFEQARRRFEAAWNHQNGENPINDSAEVQRTAQALGAQSEQLPQIGA
MUL_2305|M.ulcerans_Agy99 ADAAFDQARRRFEEAWNRQNGEHPINDSAEVQRVAQSLGAQSLELPKIGV
Mb2820c|M.bovis_AF2122/97 LSIFANSGGKTAEAAAHHNAGIR--RDLDAHGNEALAVARAADRAADGIV
Rv2797c|M.tuberculosis_H37Rv LSIFANSGGKTAEAAAHHNAGIR--RDLDAHGNEALAVARAADRAADGIV
TH_3653|M.thermoresistible__bu --------------------------------------------------
MSMEG_5089|M.smegmatis_MC2_155 MKASVEAAAP--DDRWQGSGANAYAAANKEHAQVYQKLADLDQKMAAEVK
MAB_1285c|M.abscessus_ATCC_199 AIVDMSTWQGDAGEAARDAMKRSAARFDNAGFEALYVAMHANKAYGESQT
MMAR_1534|M.marinum_M HLEEVAAALAEAQKGAAGRIATLEIQLQDLDDLIAQAMEMEKDPHLSAAD
MUL_2305|M.ulcerans_Agy99 DLENIAAALAEVQRSSSGKIAGLEGQLRQLDDEIGQAVMLERNHQLTAED
Mb2820c|M.bovis_AF2122/97 KVQSELAALRHAAAAAELTIDALINRVVPIPGLRSTEAQWARTLAKQTEL
Rv2797c|M.tuberculosis_H37Rv KVQSELAALRHAAAAAELTIDALINRVVPIPGLRSTEAQWARTLAKQTEL
TH_3653|M.thermoresistible__bu --------------------------------------------------
MSMEG_5089|M.smegmatis_MC2_155 NAANVVSAGRTNLDNAKSWVEGMANSLPATSQQDRERKLIPIAREGINRV
MAB_1285c|M.abscessus_ATCC_199 LADDIGAFLAYAAAPPKVDINPKTNAVTPPDISGLNKEQLQKVIDKLKDL
MMAR_1534|M.marinum_M RNALDAIITACEDDAIRDTEDALRRLHSIRNCYSDILQKGQTNLAADGYD
MUL_2305|M.ulcerans_Agy99 KAALDAFMHACEDDAIRDTQAALAELNSIRDGYSNFLRTAEKSLAVDGFD
Mb2820c|M.bovis_AF2122/97 QAELDAIMAEAN-----AVDEELASAVNMADGDAPIPADSGPPVGPEGLT
Rv2797c|M.tuberculosis_H37Rv QAELDAIMAEAN-----AVDEELASAVNMADGDAPIPADSGPPVGPEGLT
TH_3653|M.thermoresistible__bu --------------------------------------------------
MSMEG_5089|M.smegmatis_MC2_155 DNIVKSATADMMG--IKGNVEKLRGEYDTIKTTMRFGPESEKKPGDKKDD
MAB_1285c|M.abscessus_ATCC_199 QQRVTGLVARGEM-----LDDSLARVLDEGTGGHTMAQKQIAEGTPEQAE
MMAR_1534|M.marinum_M PARVRGADG--------HEAETPRQAERDVHDAL-AGDLGAAARVSGVLG
MUL_2305|M.ulcerans_Agy99 PARIWGADN--------HEPESAEQAEQDVHDAL-AGDQGAAGRVNAVLG
Mb2820c|M.bovis_AF2122/97 PTQLASDAN--------EERLREERARLQAHLER-LQAEYDQLSVRAAR-
Rv2797c|M.tuberculosis_H37Rv PTQLASDAN--------EERLREERARLQAHLER-LQAEYDQLSVRAAR-
TH_3653|M.thermoresistible__bu --------------------------------------------------
MSMEG_5089|M.smegmatis_MC2_155 AQMLGNEEKDDDGIPEMHAPSTEDQARMDVEQVLSEGDGGAAERVDEVLS
MAB_1285c|M.abscessus_ATCC_199 RDVHDVLAG---------TATEEQKARVQAASILSPEQIADRDAGRPVQ-
MMAR_1534|M.marinum_M SITPDQLAGKTPLNAEQASVLSQLQAQEHGMSVDALKTAEQRLGVERAII
MUL_2305|M.ulcerans_Agy99 SITPDQLAGKVPLTAEQASVLSQLQAQEHGMSVEALAAAEQRLGAQRGMI
Mb2820c|M.bovis_AF2122/97 DYHNGILDG--DAVGRLAALTDELSAARG--RLGELDAVDEALSRAPETY
Rv2797c|M.tuberculosis_H37Rv DYHNGILDG--DAVGRLAALTDELSAARG--RLGELDAVDEALSRAPETY
TH_3653|M.thermoresistible__bu --------------------------------------------------
MSMEG_5089|M.smegmatis_MC2_155 SIKP-----GDELTPQQDAYLSEMQRQQKGMSVEDLRAAEQRLGDHKNVI
MAB_1285c|M.abscessus_ATCC_199 ------------LTRPQQQVLGQLQAQMNGMSVEDIHRAEQRLGNNKSII
MMAR_1534|M.marinum_M GDSWQLMSNPNLNFPKTD------------TKVGAQEGSETMQGGFSQLP
MUL_2305|M.ulcerans_Agy99 ADSWQLMSNPNMSFPKTP------------LTVGAKQGSDTVKGGVTQLP
Mb2820c|M.bovis_AF2122/97 LTQLQIPEDPNQ-QVLAA------------VAVGNPDTAANVSVTVPGVG
Rv2797c|M.tuberculosis_H37Rv LTQLQIPEDPNQ-QVLAA------------VAVGNPDTAANVSVTVPGVG
TH_3653|M.thermoresistible__bu --------------------------------------------------
MSMEG_5089|M.smegmatis_MC2_155 ADSWQLMSNDDVEYSAGAGDD---------KKGAASQLPDSVQKALTNAG
MAB_1285c|M.abscessus_ATCC_199 GNALQMMGSNQYGYAKTELRPGAQGSTTELTTGGYDKLPTSVQEALNDKS
MMAR_1534|M.marinum_M -----QSLQNALTFNEPSHPNSANDIAEIAKVAGDGSPRLQHGTELDKAM
MUL_2305|M.ulcerans_Agy99 -----ESVQQALNSPGALFTHQMNDIAGIVK---DGDKGFQPNTELDRAM
Mb2820c|M.bovis_AF2122/97 -----STTRGALPGMVTEARDLRSEVIRQLN------AAGKPASVATIAW
Rv2797c|M.tuberculosis_H37Rv -----STTRGALPGMVTEARDLRSEVIRQLN------AAGKPASVATIAW
TH_3653|M.thermoresistible__bu ----------------------MKDISAIVR---DGDPELQTGTQVDRHM
MSMEG_5089|M.smegmatis_MC2_155 -----DTWPIGDGIGQLRYEGDLKAISEIVK---DGNPGFQTGTELDRQL
MAB_1285c|M.abscessus_ATCC_199 PGFSYVSQGPGQGTAPITQGSTLGNLDRLSDVIKDGDPGFQNGTELDRRL
: : :
MMAR_1534|M.marinum_M LDWGTRELHEEMPHGQIVDHS----LLHGAQRSTLDDVFRVAGRDHVRVT
MUL_2305|M.ulcerans_Agy99 IHKASVMMDTPIWHADPASQGQDV-ERDPVLDPAVSNVLSAVSPDHQVVH
Mb2820c|M.bovis_AF2122/97 MGYHPPPNPLDTGSAGDLWQTMTD-GQAHAGAADLSRYLQQVRANNPSGH
Rv2797c|M.tuberculosis_H37Rv MGYHPPPNPLDTGSAGDLWQTMTD-GQAHAGAADLSRYLQQVRANNPSGH
TH_3653|M.thermoresistible__bu IDKADRMMDAPIWEKDPASNGGSLDQRDPYLDGVVSDIFTSAGRDHIAVG
MSMEG_5089|M.smegmatis_MC2_155 IVAADKAMDARDIPGG----------QILGRESTVQSLFEAVDDDHQIIN
MAB_1285c|M.abscessus_ATCC_199 MQRGADILHFENQNHDS---------HEGAADSTIQNIFSSAGRDHIVDH
: :. : . ::
MMAR_1534|M.marinum_M DLLTGS---GHDQFLFDVTHNRWDDGGKGIGSLFSWTQNPG-------GP
MUL_2305|M.ulcerans_Agy99 DTITGA---DHDKFLENITHHYWKDNGQGVGSLFSWTGDPAVV----QGP
Mb2820c|M.bovis_AF2122/97 LTVLGH---SYGSLTASLALQDLDAQSAHPVNDVVFYGSPGLE----LYS
Rv2797c|M.tuberculosis_H37Rv LTVLGH---SYGSLTASLALQDLDAQSAHPVNDVVFYGSPGLE----LYS
TH_3653|M.thermoresistible__bu EHLLSE---KGDDFQG-VEVQAMPPR--------WITHDPE-------GR
MSMEG_5089|M.smegmatis_MC2_155 DHLMGRNGVDVDDFLRDVNTTDWPDNGKAAGYLFSWTNEAS------SGP
MAB_1285c|M.abscessus_ATCC_199 DMMVNPEGKRNDQFLGDLTHHQFTDGGKAAGSLMSWTHDSAHVGPGVSAD
: . ..: : ..
MMAR_1534|M.marinum_M EAELAGKTAHAYASYLGQHPGDLLNLPNG-----FSTTTLGEANPELVQS
MUL_2305|M.ulcerans_Agy99 QEGIAADTAHAYSSYIGNNQQELLHLPG--------NHTLGQVNPNLVRD
Mb2820c|M.bovis_AF2122/97 PAQLGLDHGHAYVMQAP-------------------HDLITNLVAPLAPL
Rv2797c|M.tuberculosis_H37Rv PAQLGLDHGHAYVMQAP-------------------HDLITNLVAPLAPL
TH_3653|M.thermoresistible__bu VRILSYGEVHDLPCATP---------------------SFSEYNRTLAEA
MSMEG_5089|M.smegmatis_MC2_155 EAHIAAEVADKYAGYIGEHRTDLMNFDG---------QTLGQRNPELVQQ
MAB_1285c|M.abscessus_ATCC_199 QAKLSGETAHAYASYVADHKELNALPANDNQGLGQGTKTLGQLSPELVKG
:. . : : *.
MMAR_1534|M.marinum_M FAHGLAPYIPNIAGEH----NEFSQFFATPDSAENQENESWPAAKGIFSV
MUL_2305|M.ulcerans_Agy99 MAHGLGPYVNNIAETS----GGLPGFGDPLDGKTLSG--ALPVAKGVFSV
Mb2820c|M.bovis_AF2122/97 HGWGLDPYLT--------------------------------------PG
Rv2797c|M.tuberculosis_H37Rv HGWGLDPYLT--------------------------------------PG
TH_3653|M.thermoresistible__bu TEQTLG------------------------------------------QG
MSMEG_5089|M.smegmatis_MC2_155 YAHGLVPFVDDMAGNN----GSGGEFEIDTEKDRRAG--LMPNAKGVFSV
MAB_1285c|M.abscessus_ATCC_199 MAWGLAPYTAAIGGGDPAIFGSTPGFDNALDTDDAIGNGSMPQAKALFKV
*
MMAR_1534|M.marinum_M LSTDKSASDYFNGAADRNIIQAEKHFAQSAANQVPDLINHDEDLKYAARL
MUL_2305|M.ulcerans_Agy99 LSSDNEAAQYFNGQAYAQAVLHEGAFAADPTHSG-----YNQHLYDAATL
Mb2820c|M.bovis_AF2122/97 FTELSSQAGFDPGGIWRDGVYAHGDYPRSFLDAAG-----QPQLRMSGYN
Rv2797c|M.tuberculosis_H37Rv FTELSSQAGFDPGGIWRDGVYAHGDYPRSFLDAAG-----QPQLRMSGYN
TH_3653|M.thermoresistible__bu SSEHMKSAPTYRYNQVSEVMNPQTDQPEPP--------------------
MSMEG_5089|M.smegmatis_MC2_155 LNTDPTAATTINSAAISQAMIAETAFAENPNDPLA-----HSYLSSAATL
MAB_1285c|M.abscessus_ATCC_199 LSTNAEAATTLGGALYGDSVMATNHYAEAVKHSGVG---EIGDLDQAGRF
. : : : .
MMAR_1534|M.marinum_M KGLIDVGTYNASNADLT-------AAYNLKKSAYESLLKGGTFGVGTLPI
MUL_2305|M.ulcerans_Agy99 RALVDVGAHNGFQANEDNGYHQDVSEYQSKKSAYETGLQGLTAAGGFVPG
Mb2820c|M.bovis_AF2122/97 LAAIAAG---------------------LPDNTVGPPLLPPILGGGMPAA
Rv2797c|M.tuberculosis_H37Rv LAAIAAG---------------------LPDNTVGPPLLPPILGGGMPAA
TH_3653|M.thermoresistible__bu --------------------------------------------------
MSMEG_5089|M.smegmatis_MC2_155 RGLVDVGAHEAFQAFNENGYNAGVDETTWKKAGFDAAVTAFSTGSTFVPG
MAB_1285c|M.abscessus_ATCC_199 RGLADAGLAAGNDAQHKADTVSK-EQYAKDLQRLKETAYGAITKILPIPA
MMAR_1534|M.marinum_M PGAGIVGGGTNLIGSAIEHDIVGPAPTT---TSIPDMPHTTPPRLVLDGF
MUL_2305|M.ulcerans_Agy99 VGR-IAGPTIGVLGQNLENGILGPAPTAPTENPIQPMSLGMADQEILNAM
Mb2820c|M.bovis_AF2122/97 PGPALRGGR-----------------------------------------
Rv2797c|M.tuberculosis_H37Rv PGPALRGGR-----------------------------------------
TH_3653|M.thermoresistible__bu --------------------------------------------------
MSMEG_5089|M.smegmatis_MC2_155 VGVVASPVIS-QVGSIFSNEFFE-NPPGPVERPLPQLSEPVATTTLLNAM
MAB_1285c|M.abscessus_ATCC_199 EAATPFGIMSDALKDSIVG--KAPEPGQPANTTVPNLNPAYGQQQLLNAY
MMAR_1534|M.marinum_M LASGQPLSGLEPELYRPVDPQHPDGPMRIATYAEMRKEWQQTHPIDEYNS
MUL_2305|M.ulcerans_Agy99 LGTGHTVTGLPPG-YILYDDDHPNG--RIATLEELE---PQGVTPGQYSN
Mb2820c|M.bovis_AF2122/97 --------------------------------------------------
Rv2797c|M.tuberculosis_H37Rv --------------------------------------------------
TH_3653|M.thermoresistible__bu --------------------------------------------------
MSMEG_5089|M.smegmatis_MC2_155 LAANQPLD-LPPGYVVGNEVVQPPG--------------VSDHEFAATLN
MAB_1285c|M.abscessus_ATCC_199 AATGVLRPEQFPPNMLVPDPKHPGVMRVGTLEELRQMKGPDDRPVYEHLT
MMAR_1534|M.marinum_M KLSSALSQTLGNDTVTR---IDSDISTYYNNVVHNPQP--WKK-
MUL_2305|M.ulcerans_Agy99 VIGPALSQSLEPRPPSESLSPDAALVSRYDDIVGVPHPDQGRK-
Mb2820c|M.bovis_AF2122/97 --------------------------------------------
Rv2797c|M.tuberculosis_H37Rv --------------------------------------------
TH_3653|M.thermoresistible__bu --------------------------------------------
MSMEG_5089|M.smegmatis_MC2_155 AEIGRQTVTVDGDGPDEIYADQYNLIIQDPDIQAPPTATRSENK
MAB_1285c|M.abscessus_ATCC_199 SDKYHTMVNEALRRIPGDAGSAQPLIDAYNNAVKTTE-------