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QLRYISVPALVAYAGGDPWAINQSLQAGRPAQISDLATAFHAAGRSTAESNITFEQARRRFEAAWNHQNG ENPINDSAEVQRTAQALGAQSEQLPQIGAHLEEVAAALAEAQKGAAGRIATLEIQLQDLDDLIAQAMEME KDPHLSAADRNALDAIITACEDDAIRDTEDALRRLHSIRNCYSDILQKGQTNLAADGYDPARVRGADGHE AETPRQAERDVHDALAGDLGAAARVSGVLGSITPDQLAGKTPLNAEQASVLSQLQAQEHGMSVDALKTAE QRLGVERAIIGDSWQLMSNPNLNFPKTDTKVGAQEGSETMQGGFSQLPQSLQNALTFNEPSHPNSANDIA EIAKVAGDGSPRLQHGTELDKAMLDWGTRELHEEMPHGQIVDHSLLHGAQRSTLDDVFRVAGRDHVRVTD LLTGSGHDQFLFDVTHNRWDDGGKGIGSLFSWTQNPGGPEAELAGKTAHAYASYLGQHPGDLLNLPNGFS TTTLGEANPELVQSFAHGLAPYIPNIAGEHNEFSQFFATPDSAENQENESWPAAKGIFSVLSTDKSASDY FNGAADRNIIQAEKHFAQSAANQVPDLINHDEDLKYAARLKGLIDVGTYNASNADLTAAYNLKKSAYESL LKGGTFGVGTLPIPGAGIVGGGTNLIGSAIEHDIVGPAPTTTSIPDMPHTTPPRLVLDGFLASGQPLSGL EPELYRPVDPQHPDGPMRIATYAEMRKEWQQTHPIDEYNSKLSSALSQTLGNDTVTRIDSDISTYYNNVV HNPQPWKK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_1534 | - | - | 100% (779) | hypothetical protein MMAR_1534 |
| M. marinum M | MMAR_3061 | - | 0.0 | 49.44% (799) | hypothetical protein MMAR_3061 |
| M. marinum M | MMAR_5468 | - | 6e-63 | 54.25% (212) | hypothetical protein MMAR_5468 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2105 | - | 2e-71 | 64.15% (212) | hypothetical protein Mb2105 |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv2079 | - | 3e-71 | 64.15% (212) | hypothetical protein Rv2079 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1285c | - | 4e-75 | 32.90% (693) | hypothetical protein MAB_1285c |
| M. avium 104 | MAV_0031 | - | 8e-66 | 59.36% (219) | hypothetical protein MAV_0031 |
| M. smegmatis MC2 155 | MSMEG_5089 | - | 2e-69 | 35.28% (513) | hypothetical protein MSMEG_5089 |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_2305 | - | 1e-175 | 47.15% (772) | hypothetical protein MUL_2305 |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1534|M.marinum_M MQLRYISVPALVAYAGGDPWAINQSLQAGRPAQISDLATAFHAAGRSTAE
MUL_2305|M.ulcerans_Agy99 ---------------MGD----RSKPPSGSPGADFGPGGAFHAAGRCTAE
Mb2105|M.bovis_AF2122/97 MQLRHINIRALIAEAGGDPWAIEHSLHAGRPAQIAELAEAFHAAGRCTAE
Rv2079|M.tuberculosis_H37Rv MQLRHINIRALIAEAGGDPWAIEHSLHAGRPAQIAELAEAFHAAGRYTAE
MSMEG_5089|M.smegmatis_MC2_155 -------------MGALDGFYSTWNKARETFGQGAPTDGSQFDQSRSLTQ
MAB_1285c|M.abscessus_ATCC_199 -------------------MGMTLAELQEWPPHIKALADAASKRGDASQQ
MAV_0031|M.avium_104 MGLPYIDKQALIAEAGGDPWAINASLQAGSPSQISNLAGAFHRAGRCTQE
: . :
MMAR_1534|M.marinum_M SNITFEQARRRFEAAWNHQNGENPINDSAEVQRTAQALGAQSEQLPQIGA
MUL_2305|M.ulcerans_Agy99 ADAAFDQARRRFEEAWNRQNGEHPINDSAEVQRVAQSLGAQSLELPKIGV
Mb2105|M.bovis_AF2122/97 ANAAFEEARRRFEASWNRENGEHPINDSAEVQRVTAALGVQSLQLPKIGV
Rv2079|M.tuberculosis_H37Rv ANAAFEEARRRFEASWNRENGEHPINDSAEVQRVTAALGVQSLQLPKIGV
MSMEG_5089|M.smegmatis_MC2_155 MKASVEAAAP--DDRWQGSGANAYAAANKEHAQVYQKLADLDQKMAAEVK
MAB_1285c|M.abscessus_ATCC_199 AADKVQAIVD--MSTWQGDAGEAARDAMKRSAARFDNAGFEALYVAMHAN
MAV_0031|M.avium_104 ADNAFQQARSRFDAAWNHQDGDHPINDSEEVQRVTKALGAQSLQLPKIGA
.: *: . .: . . :.
MMAR_1534|M.marinum_M HLEEVAAALAEAQKGAAGRIATLEIQLQDLDDLIAQAMEMEKDPHLSAAD
MUL_2305|M.ulcerans_Agy99 DLENIAAALAEVQRSSSGKIAGLEGQLRQLDDEIGQAVMLERNHQLTAED
Mb2105|M.bovis_AF2122/97 DLENIAADLAEAQRAAAGRIATLESQLQRIDDQLDQALELEHDPRLAAAE
Rv2079|M.tuberculosis_H37Rv DLENIAADLAEAQRAAAGRIATLESQLQRIDDQLDQALELEHDPRLAAAE
MSMEG_5089|M.smegmatis_MC2_155 NAANVVSAGRTNLDNAKSWVEGMANSLPATSQQDRERKLIP----IAREG
MAB_1285c|M.abscessus_ATCC_199 KAYGESQTLADDIG-----------AFLAYAAAPPKVDINPKTNAVTPPD
MAV_0031|M.avium_104 DLEGIAAALAEAQKAGAARIATLDAQLKNISDLVVEAVALLNDKSLSPPD
. : : ::
MMAR_1534|M.marinum_M RNALDAIITACEDDAIRDTEDALRRLHSIRNCYSDILQKGQTNLAADG--
MUL_2305|M.ulcerans_Agy99 KAALDAFMHACEDDAIRDTQAALAELNSIRDGYSNFLRTAEKSLAVDG--
Mb2105|M.bovis_AF2122/97 RSELDALITCLEQDAIDDTASALGQLQSIRAGYSDHLQQSLAMLRADG--
Rv2079|M.tuberculosis_H37Rv RSELDALITCLEQDAIDDTASALGQLQSIRAGYSDHLQQSLAMLRADG--
MSMEG_5089|M.smegmatis_MC2_155 INRVDNIVKSATADMMG-IKGNVEKLRGEYDTIKTTMRFGPESEKKPGDK
MAB_1285c|M.abscessus_ATCC_199 ISGLNKEQLQKVIDKLKDLQQRVTGLVARGEMLDDSLAR-VLDEGTGG--
MAV_0031|M.avium_104 RDALHALINTCENDALRDTKAALADLQAIRNGYADGLQKSLNSLHAEG--
:. * : : * . : *
MMAR_1534|M.marinum_M YDPARVRGADG---------HEAETPRQAERDVHDALAGDL----GAAAR
MUL_2305|M.ulcerans_Agy99 FDPARIWGADN---------HEPESAEQAEQDVHDALAGDQ----GAAGR
Mb2105|M.bovis_AF2122/97 YDGAGLQGLD-----------APQSPVKLEEPIQIPPPG------TGAPE
Rv2079|M.tuberculosis_H37Rv YDGAGLQGLD-----------APQSPVKPEEPIQIPPPG------TGAPE
MSMEG_5089|M.smegmatis_MC2_155 KDDAQMLGNEEKDDDGIPEMHAPSTEDQARMDVEQVLSEGDG---GAAER
MAB_1285c|M.abscessus_ATCC_199 HTMAQKQIAEG-------------TPEQAERDVHDVLAGTATEEQKARVQ
MAV_0031|M.avium_104 YDGAPLHGVDADG---------VAPASPAQQAALDDIRR------ATNQA
* : . .
MMAR_1534|M.marinum_M VSGVLGS--ITPDQLAGKTPLNAEQASVLSQLQAQEHGMSVDALKTAEQR
MUL_2305|M.ulcerans_Agy99 VNAVLGS--ITPDQLAGKVPLTAEQASVLSQLQAQEHGMSVEALAAAEQR
Mb2105|M.bovis_AF2122/97 VHRWWTS--LTSEERQRLIAEHPEQIGNLNGVPVSAR--SDANIAVMTRD
Rv2079|M.tuberculosis_H37Rv VHRWWTS--LTSEERQRLIAEHPEQIGNLNGVPVSAR--SDANIAVMTRD
MSMEG_5089|M.smegmatis_MC2_155 VDEVLSS--IKPGD-----ELTPQQDAYLSEMQRQQKGMSVEDLRAAEQR
MAB_1285c|M.abscessus_ATCC_199 AASILSPEQIADRDAGRPVQLTRPQQQVLGQLQAQMNGMSVEDIHRAEQR
MAV_0031|M.avium_104 VLDQMAK------------VRAAQRALDKAMADVYAHGPGSPEGEAASAQ
. : . .
MMAR_1534|M.marinum_M LGVERAIIGDSWQLMSNPNLNFPK---TDTKVGAQ-EGSETMQGGFSQLP
MUL_2305|M.ulcerans_Agy99 LGAQRGMIADSWQLMSNPNMSFPK---TPLTVGAK-QGSDTVKGGVTQLP
Mb2105|M.bovis_AF2122/97 LNRVRDIATRYRTSVDDVLGDPAK---YGLSAGDI-TRYRNADETKKGLD
Rv2079|M.tuberculosis_H37Rv LNRVRDIATRYRTSVDDVLGDPAK---YGLSAGDI-TRYRNADETKKGLD
MSMEG_5089|M.smegmatis_MC2_155 LGDHKNVIADSWQLMSNDDVEYSAGAGDDKKGAAS-QLPDSVQKALTNAG
MAB_1285c|M.abscessus_ATCC_199 LGNNKSIIGNALQMMGSNQYGYAK---TELRPGAQGSTTELTTGGYDKLP
MAV_0031|M.avium_104 LPKLKADLAHALDDLG-KIPDYTG--IDPASVNVTPDGHFMFTYNVNGQP
* : :. .
MMAR_1534|M.marinum_M QSLQNALTFNEP-------------------SHPNSANDIAEIAKVAGDG
MUL_2305|M.ulcerans_Agy99 ESVQQALNSPGA-------------------LFTHQMNDIAGIVK---DG
Mb2105|M.bovis_AF2122/97 HNARNDPRNPSP-------------------VYLFAYDPMAFGGK-----
Rv2079|M.tuberculosis_H37Rv HNARNDPRNPSP-------------------VYLFAYDPMAFGGK-----
MSMEG_5089|M.smegmatis_MC2_155 DTWPIGDGIGQL-------------------RYEGDLKAISEIVK---DG
MAB_1285c|M.abscessus_ATCC_199 TSVQEALNDKSPGFSYVSQGPGQGTAPITQGSTLGNLDRLSDVIK---DG
MAV_0031|M.avium_104 VQVVGQLQNGTG-------------------EFFDQATGTYYTFN-----
:
MMAR_1534|M.marinum_M SPRLQHGTELDKAMLDWGTRELHEEMPHGQIVDHS---LLHGAQRSTLDD
MUL_2305|M.ulcerans_Agy99 DKGFQPNTELDRAMIHKASVMMDTPIWHADPASQGQDVERDPVLDPAVSN
Mb2105|M.bovis_AF2122/97 --------GRAAIAIGNPDTAKHTAVIVPGTSSSVKGGWLHDNHDDALNL
Rv2079|M.tuberculosis_H37Rv --------GRAAIAIGNPDTAKHTAVIVPGTSSSVKGGWLHDNHDDALNL
MSMEG_5089|M.smegmatis_MC2_155 NPGFQTGTELDRQLIVAADKAMDARDIPGGQILGR---------ESTVQS
MAB_1285c|M.abscessus_ATCC_199 DPGFQNGTELDRRLMQRGADILHFENQNHDSHEGA--------ADSTIQN
MAV_0031|M.avium_104 -----------------GGKLTGMRTPDPGKVEAT--------SEPLWTA
MMAR_1534|M.marinum_M VFRVAGRDHVRVTDLLTGSG---HDQFLFDVTHNRWDDGGKGIGSLFSWT
MUL_2305|M.ulcerans_Agy99 VLSAVSPDHQVVHDTITGAD---HDKFLENITHHYWKDNGQGVGSLFSWT
Mb2105|M.bovis_AF2122/97 FNQAKAADPNNPTAVIAWMG---YDAPNDFTDPRIATPMLARIG------
Rv2079|M.tuberculosis_H37Rv FNQAKAADPNNPTAVIAWMG---YDAPNDFTDPRIATPMLARIG------
MSMEG_5089|M.smegmatis_MC2_155 LFEAVDDDHQIINDHLMGRNGVDVDDFLRDVNTTDWPDNGKAAGYLFSWT
MAB_1285c|M.abscessus_ATCC_199 IFSSAGRDHIVDHDMMVNPEGKRNDQFLGDLTHHQFTDGGKAAGSLMSWT
MAV_0031|M.avium_104 ITTAVGGYGLKVGGTAAWQG--LKTLFSREMLDGLTSENVMSRAMTG---
. .
MMAR_1534|M.marinum_M QNPG-------GPEAELAGKTAHAYASYLGQHPGDLLNLPNG-----FST
MUL_2305|M.ulcerans_Agy99 GDPAVV----QGPQEGIAADTAHAYSSYIGNNQQELLHLPG--------N
Mb2105|M.bovis_AF2122/97 -------------GAALAEDVNGLWVTHLGVGQN---------------V
Rv2079|M.tuberculosis_H37Rv -------------GAALAEDVNGLWVTHLGVGQN---------------V
MSMEG_5089|M.smegmatis_MC2_155 NEAS------SGPEAHIAAEVADKYAGYIGEHRTDLMNFDG---------
MAB_1285c|M.abscessus_ATCC_199 HDSAHVGPGVSADQAKLSGETAHAYASYVADHKELNALPANDNQGLGQGT
MAV_0031|M.avium_104 -------------AEVRAALAEAEYPRGIGGEPVP---------------
: . : :.
MMAR_1534|M.marinum_M TTLGEANPELVQSFAHGLAPYIPNIAG----EHNEFSQFFATPDSAENQE
MUL_2305|M.ulcerans_Agy99 HTLGQVNPNLVRDMAHGLGPYVNNIAE----TSGGLPGFGDPLDGKTLSG
Mb2105|M.bovis_AF2122/97 TVLGHSYGSTTVADAFALGGMHANDAV----LLG----------------
Rv2079|M.tuberculosis_H37Rv TVLGHSYGSTTVADAFALGGMHANDAV----LLG----------------
MSMEG_5089|M.smegmatis_MC2_155 QTLGQRNPELVQQYAHGLVPFVDDMAG----NNGSGGEFEIDTEKDRRAG
MAB_1285c|M.abscessus_ATCC_199 KTLGQLSPELVKGMAWGLAPYTAAIGGGDPAIFGSTPGFDNALDTDDAIG
MAV_0031|M.avium_104 STHPLEPPPVEHTPPPADAPVEHAPGG-----------------------
. . . .
MMAR_1534|M.marinum_M NESWPAAKGIFSVLSTDKSASDYFNGAADRNIIQAEKHFAQSAANQVPDL
MUL_2305|M.ulcerans_Agy99 --ALPVAKGVFSVLSSDNEAAQYFNGQAYAQAVLHEGAFAADPTHSG---
Mb2105|M.bovis_AF2122/97 ---CPGTDLAHSAASFHLDGGRVYVGAASTDPISMLGQLDSLSQYVN---
Rv2079|M.tuberculosis_H37Rv ---CPGTDLAHSAASFHLDGGRVYVGAASTDPISMLGQLDSLSQYVN---
MSMEG_5089|M.smegmatis_MC2_155 --LMPNAKGVFSVLNTDPTAATTINSAAISQAMIAETAFAENPNDPLAHS
MAB_1285c|M.abscessus_ATCC_199 NGSMPQAKALFKVLSTNAEAATTLGGALYGDSVMATNHYAEAVKHSGVG-
MAV_0031|M.avium_104 ----PHVAVPDSPPPLPPEQPPPPPLASDHPLFEGYHPIDPGPEFTN---
* . . .
MMAR_1534|M.marinum_M INHDEDLKYAARLKGLIDVGTYNASNADLT-------AAYNLKKSAYESL
MUL_2305|M.ulcerans_Agy99 --YNQHLYDAATLRALVDVGAHNGFQANEDNGYHQDVSEYQSKKSAYETG
Mb2105|M.bovis_AF2122/97 -------------------------------------------RGNLAGQ
Rv2079|M.tuberculosis_H37Rv -------------------------------------------RGNLAGQ
MSMEG_5089|M.smegmatis_MC2_155 -----YLSSAATLRGLVDVGAHEAFQAFNENGYNAGVDETTWKKAGFDAA
MAB_1285c|M.abscessus_ATCC_199 --EIGDLDQAGRFRGLADAGLAAGNDAQHKADT---VSKEQYAKDLQRLK
MAV_0031|M.avium_104 ----------------------------------------------ADGS
MMAR_1534|M.marinum_M LKGGTFGVGTLPIPGAGIVGGGTNLIGSAIEHDIVGPAPTT-----TSIP
MUL_2305|M.ulcerans_Agy99 LQGLTAAGGFVPGVGR-IAGPTIGVLGQNLENGILGPAPTAP--TENPIQ
Mb2105|M.bovis_AF2122/97 LQGLAVGLGTDPAGDG---FGSVRFRAEVPNSDGINPHDHS---------
Rv2079|M.tuberculosis_H37Rv LQGLAVGLGTDPAGDG---FGSVRFRAEVPNSDGINPHDHS---------
MSMEG_5089|M.smegmatis_MC2_155 VTAFSTGSTFVPGVGV-VASPVISQVGSIFSNEFFENPPGP---VERPLP
MAB_1285c|M.abscessus_ATCC_199 ETAYGAITKILPIPAE--AATPFGIMSDALKDSIVGKAPEPGQPANTTVP
MAV_0031|M.avium_104 LRYPDDTLPTKPYAVP----GTVVPDAQLSAGTVLSRFGFPG--------
* .. . .
MMAR_1534|M.marinum_M DMPHTTPPRLVLDGFLASGQPLSGLEPELYRPVDPQHPDGPMRIATYAEM
MUL_2305|M.ulcerans_Agy99 PMSLGMADQEILNAMLGTGHTVTGLPPG-YILYDDDHPNG--RIATLEEL
Mb2105|M.bovis_AF2122/97 --YYYHRGSEALRSMADIASGHGDALASDGMLAQPRHQPG-------VEI
Rv2079|M.tuberculosis_H37Rv --YYYHRGSEALRSMADIASGHGDALASDGMLAQPRHQPG-------VEI
MSMEG_5089|M.smegmatis_MC2_155 QLSEPVATTTLLNAMLAANQPLD-LPPGYVVGNEVVQPPG----------
MAB_1285c|M.abscessus_ATCC_199 NLNPAYGQQQLLNAYAATGVLRPEQFPPNMLVPDPKHPGVMRVGTLEELR
MAV_0031|M.avium_104 -GGYLAPEGTPFAELALPPGSAGKPYFQYVVDDPTRLPPG----------
:
MMAR_1534|M.marinum_M RKEWQQTHPIDEYNSKLSSALSQTLGNDTVTR---IDSDISTYYNNVVHN
MUL_2305|M.ulcerans_Agy99 E---PQGVTPGQYSNVIGPALSQSLEPRPPSESLSPDAALVSRYDDIVGV
Mb2105|M.bovis_AF2122/97 DIPGLGSVEIDIPGTPASIDPEWSRPPGSITDDHVFDAPLHR--------
Rv2079|M.tuberculosis_H37Rv DIPGLGSVEIDIPGTPASIDPEWSRPPGSITDDHVFDAPLHR--------
MSMEG_5089|M.smegmatis_MC2_155 ----VSDHEFAATLNAEIGRQTVTVDGDGPDEIYADQYNLIIQDPDIQAP
MAB_1285c|M.abscessus_ATCC_199 QMKGPDDRPVYEHLTSDKYHTMVNEALRRIPGDAGSAQPLIDAYNNAVKT
MAV_0031|M.avium_104 --WHIEQSEVAPWFHQPGGGQQYRIINEEGATGDVAELVRWGYLRRIN--
MMAR_1534|M.marinum_M PQP--WKK-
MUL_2305|M.ulcerans_Agy99 PHPDQGRK-
Mb2105|M.bovis_AF2122/97 ---------
Rv2079|M.tuberculosis_H37Rv ---------
MSMEG_5089|M.smegmatis_MC2_155 PTATRSENK
MAB_1285c|M.abscessus_ATCC_199 TE-------
MAV_0031|M.avium_104 ---------