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VTPVNTRVDLGPESLLWRWAGDMRIAFEGGTAGLMQTMHPAIGQGLIDHSNFFDDPVDRVFRSLPGILGT IYDGPDADATGIRVRDFHRDIKGQLPDGQRYHALKPETYWWAHATFQMMVHRLAEHWDVHRLTDRERERL YLEGCEWYRRYGMTDSVLPPTLADFNREYERYCTEVLQPNAASDFLIEFIQRTAIPDMSTSPDYPSTPLL RPIMDALLPTMPVRTALATPMRLVIFGGLPPVVRERFGIGWSGVDEASYRALRTTIKQGWRTVPASLKWH DTARRSWLRELGRIPRRF
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_3041 | - | - | 100% (298) | hypothetical protein MMAR_3041 |
| M. marinum M | MMAR_2452 | - | 3e-46 | 36.24% (287) | hypothetical protein MMAR_2452 |
| M. marinum M | MMAR_4854 | - | 2e-44 | 36.11% (288) | hypothetical protein MMAR_4854 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1672c | - | 2e-45 | 35.56% (284) | hypothetical protein Mb1672c |
| M. gilvum PYR-GCK | Mflv_0060 | - | 6e-48 | 38.18% (275) | hypothetical protein Mflv_0060 |
| M. tuberculosis H37Rv | Rv1645c | - | 2e-45 | 35.56% (284) | hypothetical protein Rv1645c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1230c | - | 1e-102 | 59.17% (289) | hypothetical protein MAB_1230c |
| M. avium 104 | MAV_3124 | - | 1e-45 | 35.31% (286) | hypothetical protein MAV_3124 |
| M. smegmatis MC2 155 | MSMEG_3781 | - | 2e-44 | 34.92% (295) | hypothetical protein MSMEG_3781 |
| M. thermoresistible (build 8) | TH_4628 | - | 2e-49 | 36.88% (301) | PUTATIVE conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_2283 | - | 1e-179 | 100.00% (295) | hypothetical protein MUL_2283 |
| M. vanbaalenii PYR-1 | Mvan_0854 | - | 5e-48 | 36.76% (272) | hypothetical protein Mvan_0854 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3041|M.marinum_M ---------------------------------MTPVNTRVDLGPESLLW
MUL_2283|M.ulcerans_Agy99 ------------------------------------MNTRVDLGPESLLW
MAB_1230c|M.abscessus_ATCC_199 ----------------------------MTTTDVISTALGAQLGRRSLLW
Mb1672c|M.bovis_AF2122/97 ----------------------------MTVASR---TSADPLGPDSLTW
Rv1645c|M.tuberculosis_H37Rv ----------------------------MTVASR---TSADPLGPDSLTW
MAV_3124|M.avium_104 ----------------------------MTGRST---TAADPLGPDSLTW
MSMEG_3781|M.smegmatis_MC2_155 ----------------------------MATRATSTDTASDPLGLDSLTW
Mflv_0060|M.gilvum_PYR-GCK ----------------------MTELADKNGHLDGADTDALPLGPQSLVW
Mvan_0854|M.vanbaalenii_PYR-1 MRAVNLVTASLVQSAESVTLLPMTELAQQTEHLD----DALPLGPQSLVW
TH_4628|M.thermoresistible__bu ----------------------MTELVETPQDARRDTPDALPLGPDSLVW
** ** *
MMAR_3041|M.marinum_M RWAGDMRIAFEGGTAGLMQTMHPAIGQGLIDHSNFFDDPVDRVFRSLPGI
MUL_2283|M.ulcerans_Agy99 RWAGDMRIAFEGGTAGLMQTMHPAIGQGLIDHSNFFDDPVDRVFRSLPGI
MAB_1230c|M.abscessus_ATCC_199 RWAGDMRIAFTGGTAGLLQTMDPAIGYALIEHSNFFADPVDRVFRSLPPI
Mb1672c|M.bovis_AF2122/97 KYFGDLRTGMMGVWIGAIQNMYPELGAGVEEHSILLREPLQRVARSVYPI
Rv1645c|M.tuberculosis_H37Rv KYFGDLRTGMMGVWIGAIQNMYPELGAGVEEHSILLREPLQRVARSVYPI
MAV_3124|M.avium_104 KYFGDLRTGMMGVWIGAIQNMYPELGAGVQEHSILLREPLQRVARSVYPI
MSMEG_3781|M.smegmatis_MC2_155 KYFGDLRTGMLGVWIGAIQNMYPELGAGVEEHSILLREPLQRVARSVYPI
Mflv_0060|M.gilvum_PYR-GCK RYFGDNRMYLIGPRPAVLQNMLAELGQGVYDHSTFFADTAERLKRTIPPI
Mvan_0854|M.vanbaalenii_PYR-1 KYFGDNRMYLIGPRPAVLQNMLAELGQGVYDHSTFFADTAERLKRTIPPI
TH_4628|M.thermoresistible__bu RYFGDNRMPLIGPRPAVLQNMLAELGQGVLDHSVFFSDTAARVRRSLPPI
:: ** * : * . :*.* . :* .: :** :: :. *: *:: *
MMAR_3041|M.marinum_M LGTIYDGPDADATGIRVRDFHRDIKGQLP--DG---QRYHALKPETYWWA
MUL_2283|M.ulcerans_Agy99 LGTIYDGPDADATGIRVRDFHRDIKGQLP--DG---QRYHALKPETYWWA
MAB_1230c|M.abscessus_ATCC_199 LGTVYDDP-AAGTGVTVRDFHRDIKGVQP--DG---VRYHALNPTTFWWA
Mb1672c|M.bovis_AF2122/97 MGVVYDGDRAAQTGQQIKGYHRTIKGVDA--EG---RRYHALNPDTFYWA
Rv1645c|M.tuberculosis_H37Rv MGVVYDGDRAAQTGQQIKGYHRTIKGVDA--EG---RRYHALNPDTFYWA
MAV_3124|M.avium_104 MGVVYDGDRAPQTGRQITSYHHTIKGTDA--SG---RRYHALNPDTFYWA
MSMEG_3781|M.smegmatis_MC2_155 MGVVYDGDRAPETGAQIKGFHKTIKGVDS--SG---RRYHALNPETFYWA
Mflv_0060|M.gilvum_PYR-GCK LNTVYGSD-EENAGLQVRDFHHHVKGVMPGPDGEEAGRYHALDPETYFWA
Mvan_0854|M.vanbaalenii_PYR-1 FNTVYGSD-ENNAGLQVRDFHHHVKGEMPGTDG---ARYHALDPETYFWA
TH_4628|M.thermoresistible__bu FMTVYGSD-DENPGRQVRDYHTEIKGTMP--DG---QRYHALDPETYFWA
: .:*.. .* : .:* :** . .* *****.* *::**
MMAR_3041|M.marinum_M HATFQMMVHRLAEHWDVHRLTDRERERLYLEGCEWYRRYGMTDSVLPPTL
MUL_2283|M.ulcerans_Agy99 HATFQMMVHRLAEHWDVHRLTDRERERLYLEGCEWYRRYGMTDSVLPPTL
MAB_1230c|M.abscessus_ATCC_199 HATFQVMVEQTIDRYSRYRLSGAEREQLYQEGVEWYRRYAMSEQPLPPNR
Mb1672c|M.bovis_AF2122/97 HATFFMLVIKVAEYFCGG-LTEAEKHQLFEEHVRWYRMYGMSMRPVPKSW
Rv1645c|M.tuberculosis_H37Rv HATFFMLVIKVAEYFCGG-LTEAEKHQLFEEHVRWYRMYGMSMRPVPKSW
MAV_3124|M.avium_104 HATFFMLIIKVAEYFCGG-LTEAEKRQLFDEHVQWYRMYGMSMRPVPKSW
MSMEG_3781|M.smegmatis_MC2_155 HATFFMLIIKTAEYFCGG-LTEAEKRQLFDEHVQWYRMYGMSMRPVPQTW
Mflv_0060|M.gilvum_PYR-GCK HATFVEQVYYFADTFVKR-LTDAEREQIWLESKTWYRRYGVSDRVMPATY
Mvan_0854|M.vanbaalenii_PYR-1 HATFVEQIYYFADTFVKR-LTDAEREQIWLESKTWYRRYGVSDRPMPATY
TH_4628|M.thermoresistible__bu HATFVDQVLYFADTFVKR-LTRAEKEQIYLESKTWYRRYGVSDRVMPATY
**** : : : *: *:.::: * *** *.:: :* .
MMAR_3041|M.marinum_M ADFNREYERYCTEVLQPNAASDFLIEFIQRTAIPDMSTSPDYPSTPLLRP
MUL_2283|M.ulcerans_Agy99 ADFNREYERYCTEVLQPNAASDFLIEFIQRTAIPDMSTSPDYPSTPLLRP
MAB_1230c|M.abscessus_ATCC_199 AAFQQEWDRYCDEVLTPNPAADYLMKVIEGRSVPDMSKSPHLPVAAYLKP
Mb1672c|M.bovis_AF2122/97 EDFQDYWDRVCRDKLEINQATVDILQMRIPK--PRFVLMPTPIWDQLFKP
Rv1645c|M.tuberculosis_H37Rv EDFQDYWDRVCRDKLEINQATVDILQMRIPK--PRFVLMPTPIWDQLFKP
MAV_3124|M.avium_104 EEFQEYWERTGREVLEINQATLDIFRMRIPK--PKFVLMPTPLWDQLFRP
MSMEG_3781|M.smegmatis_MC2_155 EEFQDYWDAKCRDELEINRATLDIFSIRIPK--PWFVLMPTPIWDQLFKP
Mflv_0060|M.gilvum_PYR-GCK AEFVQYWDRMMDQVVVAHPTAKYGVGYVTKG--FPKPKAVHPLVWRLVAP
Mvan_0854|M.vanbaalenii_PYR-1 AEFEQYWDRMMDQVVVAHPSAKYGVGYVTKG--FPKPKAVHPLVWRLVAP
TH_4628|M.thermoresistible__bu DEFERYWDRMLDEIIVAHKTAKYGVGYVTKG--FPCPKGVHPAVWKVISV
* :: : : : :: . .
MMAR_3041|M.marinum_M IMDALLPTMPVRTALATPMRLVIFGGLPPVVRERFGIGWSGVDEASYRAL
MUL_2283|M.ulcerans_Agy99 IMDALLPTMPVRTALATPMRLVIFGGLPPVVRERFGIGWSGVDEASYRAL
MAB_1230c|M.abscessus_ATCC_199 AAKLALPTAPLRMALAPPLRLTIYGGLPPQVRKRFGIRWNLADETAYRTL
Mb1672c|M.bovis_AF2122/97 --------------LIAGQRWIAAGLFDPAVREKAGMHWTPGDEVLLRVF
Rv1645c|M.tuberculosis_H37Rv --------------LIAGQRWIAAGLFDPAVREKAGMHWTPGDEVLLRVF
MAV_3124|M.avium_104 --------------LVAGQRWIAAGLFEPAVREKAGMHWTPGDEVLLRLF
MSMEG_3781|M.smegmatis_MC2_155 --------------LVGAQRWIAAGLFDPVVREKAGMRWTPGDEVLLRIF
Mflv_0060|M.gilvum_PYR-GCK -------------VFNPLAAFLTTGGLPPRARMLLGLPWSDKQERRYQRF
Mvan_0854|M.vanbaalenii_PYR-1 -------------VFNPLAAFLTTGGLPPRARMLLGLPWTDKQERRYQRF
TH_4628|M.thermoresistible__bu -------------VFDPVAAFLTTGGLPPRARTLLNLPWSEKQERRYQRF
: * : * .* .: *. :* : :
MMAR_3041|M.marinum_M R-----TTIKQGWRTVPASLKWHDTARRSWLRELGRIPRRF---------
MUL_2283|M.ulcerans_Agy99 R-----TTIKQGWRTVPASLKWHDTARRSWLRELGRIPRRF---------
MAB_1230c|M.abscessus_ATCC_199 L-----RAVPLAWPFIPTSWRWHPASHDGWRRERGRLPRNW---------
Mb1672c|M.bovis_AF2122/97 G-----KVVELAFLAVPDEIRLHPRALAAYRRAAGRTRHDAPLVQAPGFM
Rv1645c|M.tuberculosis_H37Rv G-----KVVELAFLAVPDEIRLHPRALAAYRRAAGRTRHDAPLVQAPGFM
MAV_3124|M.avium_104 G-----KIVELAFLAVPDEIRLHPRALAAYRREQGRLPSDAPLVEAPPFM
MSMEG_3781|M.smegmatis_MC2_155 G-----KAVELAFLAVPDEIRLHPRAVSAYRRAKGRIPADAPLVEAPGFT
Mflv_0060|M.gilvum_PYR-GCK AAFWRSRPVNWVWDRLPMTVRYSGYAVKGFTRSDMRSDVRA---------
Mvan_0854|M.vanbaalenii_PYR-1 AAIWRSRPVNWIWDRLPMRVRYSGYAVKGYARN-----------------
TH_4628|M.thermoresistible__bu AAFCRSRPVNWVWDRLPMKVRYNKYARRGYARAA----------------
: : :* : : .: *
MMAR_3041|M.marinum_M --------------------------------------------------
MUL_2283|M.ulcerans_Agy99 --------------------------------------------------
MAB_1230c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1672c|M.bovis_AF2122/97 APPRDRQGLPMHYFPPRSHRFTRSALDPAKALMERAGALVHSTLSLAGVR
Rv1645c|M.tuberculosis_H37Rv APPRDRQGLPMHYFPPRSHRFTRSALDPAKALMERAGALVHSTLSLAGVR
MAV_3124|M.avium_104 APPRDRRGLPMHYFPPPPRLPFDPALQPARALMERAGSLVHTTLSLAGLR
MSMEG_3781|M.smegmatis_MC2_155 APPKDRRGLPMHYLPQR------------RSLLDRAGALVHSTLSLPALR
Mflv_0060|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0854|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4628|M.thermoresistible__bu --------------------------------------------------
MMAR_3041|M.marinum_M --------------
MUL_2283|M.ulcerans_Agy99 --------------
MAB_1230c|M.abscessus_ATCC_199 --------------
Mb1672c|M.bovis_AF2122/97 PARG----PSRAA-
Rv1645c|M.tuberculosis_H37Rv PARG----PSRAA-
MAV_3124|M.avium_104 AGRGRPKRPVRAA-
MSMEG_3781|M.smegmatis_MC2_155 PAKKSS--PRRSAA
Mflv_0060|M.gilvum_PYR-GCK --------------
Mvan_0854|M.vanbaalenii_PYR-1 --------------
TH_4628|M.thermoresistible__bu --------------