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TPTAVPPEPTSEHMVGGIPLASLVRDYHRQMVNFARTMVSSPTIAEEAVQEAWVQVIQSSDSFEGRSSVA TWLFGIVKNTASRYRRRDSRIRAHEVLATEEIDPLSGRMHPAGHPDAGHWSVPPSRRFIPEDQTVAEETV GFVRAALDALPPRQRRLVILRDLLGISAEEAAHTLELSAQAQRALLYRGRGNLRAELEKRYQR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_2997 | - | - | 100% (204) | alternative RNA polymerase sigma factor |
| M. marinum M | MMAR_3276 | - | 2e-24 | 37.63% (194) | alternative RNA polymerase sigma factor |
| M. marinum M | MMAR_0426 | sigG | 3e-13 | 32.46% (191) | alternative RNA polymerase sigma factor SigG |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0188c | sigG | 4e-10 | 30.64% (173) | RNA polymerase factor sigma-70 |
| M. gilvum PYR-GCK | Mflv_0519 | - | 3e-14 | 32.75% (171) | RNA polymerase factor sigma-70 |
| M. tuberculosis H37Rv | Rv0182c | sigG | 4e-10 | 30.64% (173) | RNA polymerase factor sigma-70 |
| M. leprae Br4923 | MLBr_01076 | sigE | 7e-09 | 27.62% (181) | RNA polymerase sigma factor SigE |
| M. abscessus ATCC 19977 | MAB_4553 | - | 7e-13 | 31.11% (180) | RNA polymerase factor sigma-70 |
| M. avium 104 | MAV_2488 | - | 2e-87 | 75.85% (207) | RNA polymerase sigma factor, sigma-70 family protein |
| M. smegmatis MC2 155 | MSMEG_0219 | - | 1e-12 | 31.79% (173) | RNA polymerase factor sigma-70 |
| M. thermoresistible (build 8) | TH_0604 | sigG | 2e-13 | 29.61% (206) | PROBABLE ALTERNATIVE RNA POLYMERASE SIGMA FACTOR SIGG (RNA |
| M. ulcerans Agy99 | MUL_2238 | - | 3e-81 | 98.67% (150) | alternative RNA polymerase sigma factor |
| M. vanbaalenii PYR-1 | Mvan_0782 | - | 1e-24 | 36.56% (186) | ECF subfamily RNA polymerase sigma-24 factor |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2997|M.marinum_M -----------------------------------------MTPTAVPPE
MUL_2238|M.ulcerans_Agy99 --------------------------------------------------
MAV_2488|M.avium_104 ----------------------------------------MVTPVAVPPE
Mvan_0782|M.vanbaalenii_PYR-1 --------------------------------MTGYHLAEMTTTSADEAD
Mb0188c|M.bovis_AF2122/97 -----MRTSPMPAKFRSVRVVVITGSVTAAPVRVSETLRRLIDVSVLAEN
Rv0182c|M.tuberculosis_H37Rv -----MRTSPMPAKFRSVRVVVITGSVTAAPVRVSETLRRLIDVSVLAEN
MAB_4553|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_0519|M.gilvum_PYR-GCK ---------------------------------MSHPMRKLLFVTVLA--
MSMEG_0219|M.smegmatis_MC2_155 ---------------------------------MSVILRKLTTVTVLAH-
TH_0604|M.thermoresistible__bu ---------------------------------MSVMLRTLLHVTVLT--
MLBr_01076|M.leprae_Br4923 MGDGIGMEREGRWTGNTQCPLRVVPGDESPTLDGRASPEDLIITNLLSPT
MMAR_2997|M.marinum_M PTSE-HMVGGIPLASLVRDYHRQMVNFARTMVSSPTIAEEAVQEAWVQVI
MUL_2238|M.ulcerans_Agy99 ----------------------------------------------MQVI
MAV_2488|M.avium_104 GTDAGRLVGGVPLARLVRDFHRPMLNFARTMVDSPAVAEEAVQEAWLQVL
Mvan_0782|M.vanbaalenii_PYR-1 LIAALRARDEVAFARLVDQHTPAMLRVARGYVASHEVAEEVVQETWIALL
Mb0188c|M.bovis_AF2122/97 SGREPADERRGDFSAHTEPYRRELLAHCYRMTGSLHDAEDLVQETLLRAW
Rv0182c|M.tuberculosis_H37Rv SGREPADERRGDFSAHTEPYRRELLAHCYRMTGSLHDAEDLVQETLLRAW
MAB_4553|M.abscessus_ATCC_1997 ---MTAHAIEDEFLSHTEQYRREILAHCYRMTGSIHDAEDLVQETYLRGW
Mflv_0519|M.gilvum_PYR-GCK ---LDEGGAKDAFLADAQKYRRELLAHCYRMTGSLHDAEDLVQETYLRAW
MSMEG_0219|M.smegmatis_MC2_155 --KLDDDSPADAFLAEAQTYRRELLAHCYRMTGSLHDAEDLVQETYLRAW
TH_0604|M.thermoresistible__bu ---APPDGGSDAFLADAEQYRRELLAHCYRMTGSLHDAEDLVQETFLRAW
MLBr_01076|M.leprae_Br4923 IMSHPPPSRDDDWVEPFDALQGTAVFDATGDKATMPSWEELVRQHAARVY
MMAR_2997|M.marinum_M QSSDSFEGRSSVATWLFGIVKNTASRYRRRDSRIRAHEVLAT---EEIDP
MUL_2238|M.ulcerans_Agy99 QSSDSFEGRSSVATWLFGIVKNTASRYRRRDSRIRAHEVLAT---EEIDP
MAV_2488|M.avium_104 RSSDSFQGRSSVGTWLFGIVKHTAARHRRRESRIRRHEVLADADIEAVDP
Mvan_0782|M.vanbaalenii_PYR-1 KGIDRFEGRSSLRTWLFTVMINIAKTRGLRD-RTDADVQIAAYTGGTVDP
Mb0188c|M.bovis_AF2122/97 KAYEGFAGKSSLRTWLHRIATNTCLTALEGRRRRPLPTGLGR---PSADP
Rv0182c|M.tuberculosis_H37Rv KAYEGFAGKSSLRTWLHRIATNTCLTALEGRRRRPLPTGLGR---PSADP
MAB_4553|M.abscessus_ATCC_1997 KAYARFEGKSSVRTWLYRIATNTCLTALEGKQRRPLPTGLGA---PSADP
Mflv_0519|M.gilvum_PYR-GCK KSYDRFEGKSSVRTWLYRIATNTCLTALDGRKRRPLPSGLGG---PSADP
MSMEG_0219|M.smegmatis_MC2_155 KSYQGFQGRSSVRTWLYRIATNTCLTSLEGRSRRPLPSGLGT---PSSAP
TH_0604|M.thermoresistible__bu KSHHKFEGKASVRTWLYKIATNACLTALDGRQRRPLPTGLGA---PSSDP
MLBr_01076|M.leprae_Br4923 WLAYRLSGNQHDAEDLTQETFIRVFRSVQNYQPGTFEGWLHR---ITTNL
: *. * :
MMAR_2997|M.marinum_M LSGRMHPAGHPDAGHWS---VPPSRRFIPEDQTVAEETVGFVR-AALDAL
MUL_2238|M.ulcerans_Agy99 LSGRMHPAGHPDAGHWS---VPPSRRFIPEDQTVAEETVGFVR-AALDAL
MAV_2488|M.avium_104 LSGRMHPAGHPDAGHWR---VPPSRRFLPEDQTVHRELLGYLR-EALDAL
Mvan_0782|M.vanbaalenii_PYR-1 K--RFRDSDDPWPGHWKADEVPSPFPDTPEGSVLGGELLAVTR-RELAKL
Mb0188c|M.bovis_AF2122/97 SGELVERREVSWLEPLPDVT-DDPADPSTIVGNRESVRLAFV--AALQHL
Rv0182c|M.tuberculosis_H37Rv SGELVERREVSWLEPLPDVT-DDPADPSTIVGNRESVRLAFV--AALQHL
MAB_4553|M.abscessus_ATCC_1997 LDELDERSEIPWLEPLP----DDATDPASIVGARESVRLAFV--AALQHL
Mflv_0519|M.gilvum_PYR-GCK YADLTERHEIAWLEPIPDDPHEDPADPSVIAESRESVRLALI--AALQHL
MSMEG_0219|M.smegmatis_MC2_155 TDQITEHHEVPWLEPLPDG--DDPADPSQIVGTRESVRLAFV--AALQHL
TH_0604|M.thermoresistible__bu TDDIVAREEVPWLEPLPDD----AADPSTIVGSRESVRLAFV--AALQHL
MLBr_01076|M.leprae_Br4923 FLDMVRRRARIRMDALPDDYDRVPADEPNPEQIYHDSRLGPDLQAALDSL
. :. * *
MMAR_2997|M.marinum_M PPRQRRLVILRDLLGISAEEAAHTLELSAQAQRALLYRGRGNLRAELEKR
MUL_2238|M.ulcerans_Agy99 PPRQRRLVILRDLLGISAEEAAHTLELSAEAQRALLYRGQGNLRAELEKR
MAV_2488|M.avium_104 PARQRQLVILRDLVGISAEEAAELLQLSAEAQRALLYRARGNLRNELEKR
Mvan_0782|M.vanbaalenii_PYR-1 PERQRLVVTMRDVLDMDSAEVSRLLDLSPANQRVLLHRGRAAVRQALENY
Mb0188c|M.bovis_AF2122/97 SPRQRAVLLLRDVLQWKSAEVADAIGTSTVAVNSLLQRARSQLQTVRPSA
Rv0182c|M.tuberculosis_H37Rv SPRQRAVLLLRDVLQWKSAEVADAIGTSTVAVNSLLQRARSQLQTVRPSA
MAB_4553|M.abscessus_ATCC_1997 PAKQRAVLVLREVLQWKAQEVAEAIGSTTAAVNSLLQRARAQLHEVSP-H
Mflv_0519|M.gilvum_PYR-GCK SPRQRAVLVLREVLQWKAAEVGEVIGASTAAVNSLLQRARAQLDEVAPSR
MSMEG_0219|M.smegmatis_MC2_155 SPRQRAVLVMREVLQWKASEVGEAIGASTAAVNSLLQRARAQLEAVGPNE
TH_0604|M.thermoresistible__bu PPRQRAVLLLREVLQWRAAEVAEVLNTSTAAVNSLLQRARAQLDQVGPSE
MLBr_01076|M.leprae_Br4923 PPEFRAAVVLCDIEGLSYEEIGATLGVKLGTVRSRIHRGRQALRDYLLTA
. . * : : :: * . : . . : *.: :
MMAR_2997|M.marinum_M YQR-----------------------------------------------
MUL_2238|M.ulcerans_Agy99 YQR-----------------------------------------------
MAV_2488|M.avium_104 YQP-----------------------------------------------
Mvan_0782|M.vanbaalenii_PYR-1 LKEPV---------------------------------------------
Mb0188c|M.bovis_AF2122/97 ADRLSAPDSPEAQDLLARYIAAFEAYDIDRLVELFTAEAIWEMPPYTGWY
Rv0182c|M.tuberculosis_H37Rv ADRLSAPDSPEAQDLLARYIAAFEAYDIDRLVELFTAEAIWEMPPYTGWY
MAB_4553|M.abscessus_ATCC_1997 EETLLEPEDPMLREQLRQYINAFERYDVEAIAKMFTTEAIWEMPPFTGWY
Mflv_0519|M.gilvum_PYR-GCK DDQPVSPESPQAAEALAKYIAAFEDYDMDRLVELFTADAVWEMPPFDGWY
MSMEG_0219|M.smegmatis_MC2_155 DDKIEAPDSPQAQATLDRYIAAFEAYDIDKLVELFTEEAIWEMPPFDSWY
TH_0604|M.thermoresistible__bu DDELVPPESPEAQELLTRYIDAFESYDIDKLVELFTADAVWEMPPFDGWY
MLBr_01076|M.leprae_Br4923 HPRDGATTDATHVKSA----------------------------------
MMAR_2997|M.marinum_M --------------------------------------------------
MUL_2238|M.ulcerans_Agy99 --------------------------------------------------
MAV_2488|M.avium_104 --------------------------------------------------
Mvan_0782|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb0188c|M.bovis_AF2122/97 QGAQAIVTLIHQQCPAYSPGDMRLISLIANGQPAAAMYMRAGD--VHLPF
Rv0182c|M.tuberculosis_H37Rv QGAQAIVTLIHQQCPAYSPGDMRLISLIANGQPAAAMYMRAGD--VHLPF
MAB_4553|M.abscessus_ATCC_1997 QGGPSIAALIKEQCPAEHAGDMRLVETSANGQPAIGLYMREGDG-VHRPF
Mflv_0519|M.gilvum_PYR-GCK SGPADIIALSKYHCPAAGAGDMRFLRTTANGQPVAALYMRNPETNVHEAF
MSMEG_0219|M.smegmatis_MC2_155 QGPQAIGDLSRYKCPAEEPGDMRFLQTTANGQPAAAMYMLNRETGRHEAF
TH_0604|M.thermoresistible__bu QGPQNIVTLSKTHCPAERPGDMRLIPTTANGQPAGAMYLRNPETGTHEAF
MLBr_01076|M.leprae_Br4923 --------------------------------------------------
MMAR_2997|M.marinum_M -----------------------------------
MUL_2238|M.ulcerans_Agy99 -----------------------------------
MAV_2488|M.avium_104 -----------------------------------
Mvan_0782|M.vanbaalenii_PYR-1 -----------------------------------
Mb0188c|M.bovis_AF2122/97 QLHVLDMAADRVSHVVAFLDTTLFPKFGLPDSL--
Rv0182c|M.tuberculosis_H37Rv QLHVLDMAADRVSHVVAFLDTTLFPKFGLPDSL--
MAB_4553|M.abscessus_ATCC_1997 QMHVLDVTQDGVAHVVCFFDISLFEKFGLPAELTD
Mflv_0519|M.gilvum_PYR-GCK QLHVLDLRTRGIAHVVAFMDVSLFRKFGLPETL--
MSMEG_0219|M.smegmatis_MC2_155 QLHVLDITADGISHVVAFMGEGLFKKFGLPETL--
TH_0604|M.thermoresistible__bu QMHVLAIGPGGISHVVAFH-MPSFAPFGLPDSL--
MLBr_01076|M.leprae_Br4923 -----------------------------------