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VTYLVTVPQTVATAAGNLAAIGSSITDASAAAAAPTTELAAAGADEISAAIAQLFGTHAQIYQRISAQAM AFHDQFARSLSAASGSYANAEATNTLTLQSVQQDLLGLVNAPTQALLGRPLIGNGANGAPGTGANGEAGG ILFGSGGSGGSGGVGQNGGNGGDAGLFGSGGAGGAGGIDGGGGAGTGGTGGRGGLIFGDAGAGGQGGLGF APNPNGGGGGAGGTGGAGGLFGAGGPGGNGAPSVSGGGSGDGGDGGRGGVFGPGGRGGDGAPNPGGGSPG SGGNGGAGGLFGAGGAGGNGAPDVGGGSPGSGGNGGAGGLFFGDGGAGGNGAPNVGGGSPGAGGNGGDAG LFGAGGAGGRGGNNLANPATDGGAGGAGGNGGAGGLFAGAGGPGGQGGDNQNTNTGPGGVGGAGGDAGLF SGAIGGAGGSAGRSVGTIGSVGGAGGNGGLFGTGGAGGSGGQDGYNYGGNGGAGGLLFGVGGAGGAAALS GAGNGGTGGAGGLFFGVGGAGGAAPLFGGGTGGTGGAGGLLFGLGGAGGNAPVFGGGSGGTGGRAGLIGI GGAGGSSSVFAGGDGGAGGAGGTFIGFGGAGGDGGVSGNGGAGGKAGLIGVGGNGGNGGNGGNGGAGGDA QLIGIGGNGGNGGDGQLGGPGTGGTGGTGGTLLGLNGIDGLDGSA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_2969 | - | - | 100% (675) | PE-PGRS family protein |
| M. marinum M | MMAR_2970 | - | 0.0 | 60.22% (651) | PE-PGRS family protein |
| M. marinum M | MMAR_5044 | - | 0.0 | 49.87% (790) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1121 | PE_PGRS22 | 0.0 | 50.13% (750) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 1e-123 | 42.59% (695) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv1091 | PE_PGRS22 | 0.0 | 50.40% (750) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01183 | - | 1e-10 | 33.70% (92) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 8e-43 | 28.30% (629) | hypothetical protein MAB_4284c |
| M. avium 104 | MAV_4827 | - | 7e-26 | 39.18% (194) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 4e-98 | 40.00% (655) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 2e-39 | 37.83% (304) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_1339 | - | 1e-176 | 50.34% (745) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-119 | 48.62% (580) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2969|M.marinum_M --------------------------------------------------
MUL_1339|M.ulcerans_Agy99 --------------------------------------------------
Mb1121|M.bovis_AF2122/97 --------------------------------------------------
Rv1091|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MMAR_2969|M.marinum_M --------------------MTYLVTVPQTVATAAGNLAAIGSSITDASA
MUL_1339|M.ulcerans_Agy99 --------------------MSYVIAAPEEFASAARNLANIGVTINAANA
Mb1121|M.bovis_AF2122/97 --------------------MSFVIAAPEALVAVASDLAGIGSALAEANA
Rv1091|M.tuberculosis_H37Rv --------------------MSFVIAAPEALVAVASDLAGIGSALAEANA
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -----------------MSIIDFILNLFRDPVEAASYVADPEAALANAGL
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ----------------MNIVLGVSMAPSSIQMVVLEGEYADGATVEEDAI
MMAR_2969|M.marinum_M AAAAPTTELAAAGADEISAAIAQLFGTHAQIYQRISAQAMAFHDQFARSL
MUL_1339|M.ulcerans_Agy99 NAILATTEVIQPGADAVSAAITALINSHGLGYQSISQQTTAFHDRFVQTV
Mb1121|M.bovis_AF2122/97 AALAPTTALLAAGADEVSAAIAALFGAHGQAYQTVSAQASAFHAQFVQAL
Rv1091|M.tuberculosis_H37Rv AALAPTTALLAAGADEVSAAIAALFGAHGQAYQTVSAQASAFHAQFVQAL
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 SAVSAAQVGAVMPVVAESVASNYGYQSQWVNTGNPIHDLSGNLQNYYAAQ
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 DVTGADDAATASAPDRVISAILGTREGAADAGLQLSSIGVTWTDQLEAAA
MMAR_2969|M.marinum_M SAASG----------------------SYANAEATNTLTLQSVQQDLLGL
MUL_1339|M.ulcerans_Agy99 NAAAA----------------------SYT----TTDLTAASLLKSMPTA
Mb1121|M.bovis_AF2122/97 TGGGG----------------------AYAAAEAANVSAAQSTDQRLLDL
Rv1091|M.tuberculosis_H37Rv TGGGG----------------------AYAAAEAANVSAAQSTDQRLLDL
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 PDGPS------------------------------------ILSPSLLSP
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 LRDALAAR------------------RIDNVMLVSAFLAAAALAQNVGGA
MMAR_2969|M.marinum_M VN--------------------APTQALLG--------RPLIGNGANGAP
MUL_1339|M.ulcerans_Agy99 VN--------------------APAQALFG--------RPLIGNGSNGTP
Mb1121|M.bovis_AF2122/97 IN--------------------GPTQALLG--------RPLIGDGANGGP
Rv1091|M.tuberculosis_H37Rv IN--------------------GPTQALLG--------RPLIGDGANGGP
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 RD------------------------------------NDFLSHNDTDFA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 MG----------------------YERTAVLLVEPDTATLAVVETSDGSI
MMAR_2969|M.marinum_M GTGANGEAGGILFGSGGSGG-SGGVGQNGGNGGDAGLFG-SGGAGGAGGI
MUL_1339|M.ulcerans_Agy99 GTGAPGGDGGILFGSGGAGG-SGAGGQDGGAGGRAGLFG-NGGAGGAG--
Mb1121|M.bovis_AF2122/97 GQ--DGGPGGLLYGNGGNGGTSTTAGVAGGNGGAAGLIG-NGGAGGGG--
Rv1091|M.tuberculosis_H37Rv GQ--DGGPGGLLYGNGGNGGTSTTAGVAGGNGGAAGLIG-NGGAGGGG--
Mflv_5091|M.gilvum_PYR-GCK QN------GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNG--
Mvan_1264|M.vanbaalenii_PYR-1 QN------GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNG--
MSMEG_0868|M.smegmatis_MC2_155 DNP-NGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVG--
TH_3810|M.thermoresistible__bu -----------VDGDGGSGGRTGLFSKLSRGG--------DGGDGGLG--
MAB_4284c|M.abscessus_ATCC_199 SHN-PIASGNQVMSPSGNVDSFNRGPLLDLSFGDLQFGNRDTTAIGDG--
MLBr_01183|M.leprae_Br4923 --------MPLFLNAEPQALTAAANTLEGLSAATVAS---NAAAAQLT--
MAV_4827|M.avium_104 PDVYKQQIRAESYGDAAGQLSAMVAGLEKLESLPGGLLLVGSGVDVAPLK
. .
MMAR_2969|M.marinum_M DGGGGAGTGGTGGRGG--LIFGDAGAGGQGGLGFA----------PNPNG
MUL_1339|M.ulcerans_Agy99 --GTGQTQGGAGGAGG--LFFGNGGAGGPGGSG-------------GLNG
Mb1121|M.bovis_AF2122/97 ---GAGAAGGNGGAGG--WLYGNGGAGGAGGTSVI----------PGVAG
Rv1091|M.tuberculosis_H37Rv ---GAGAAGGNGGAGG--WLYGNGGAGGAGGTSVI----------PGVAG
Mflv_5091|M.gilvum_PYR-GCK ---LGGGNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAG
Mvan_1264|M.vanbaalenii_PYR-1 ---LGSGDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAG
MSMEG_0868|M.smegmatis_MC2_155 ---WAGLDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGG
TH_3810|M.thermoresistible__bu ------GNGGHGGGTGIISLLSLAGNGGNGGNGYRTTDN------NALDG
MAB_4284c|M.abscessus_ATCC_199 -------AVAVGGSNSGPIASGQGSTAVNGDVRDS----------NIINA
MLBr_01183|M.leprae_Br4923 ------TEIAPPAADDVSILLAHFFSG--HGRQYQ------------AHA
MAV_4827|M.avium_104 QVLQTTTFLDVSVAEEPETALARGAALAAANAPLFAS--------STAAL
. .
MMAR_2969|M.marinum_M GGGGAGGTGGAGGLFG-----AGGPGGNGAPS---VSGGGS---------
MUL_1339|M.ulcerans_Agy99 GAGGAGGVG--GLLFG-----AGGAGGAGGSG---TSGIG----------
Mb1121|M.bovis_AF2122/97 GNGGAGGSAGLWGTGG-----AGGDGGNGRSGPVNVAGSAG---------
Rv1091|M.tuberculosis_H37Rv GNGGAGGSAGLWGTGG-----AGGDGGNGRSGPVNVAGSAG---------
Mflv_5091|M.gilvum_PYR-GCK ATGATGVTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG---------
Mvan_1264|M.vanbaalenii_PYR-1 ATGATGVTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG---------
MSMEG_0868|M.smegmatis_MC2_155 TGGGTGGTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLI
TH_3810|M.thermoresistible__bu GHGGNGGNVGFFSLFN-----LGGAGGWGGSGVDGVDVVGG---------
MAB_4284c|M.abscessus_ATCC_199 DHGSNVGVDQSQTRVGGDYTNVSGHGSADIDKSVTVVDDHS---------
MLBr_01183|M.leprae_Br4923 SQGATNHQDLIQSLLT-------SSSAYAGTETANHDSL-----------
MAV_4827|M.avium_104 AYAQDPGTGAVDQYSLPDYLYVPVDPEPGDDELAYSAVGEE---------
.
MMAR_2969|M.marinum_M ----------GDGGDGGRGGVFGP---GGRGGDGAPN----------PGG
MUL_1339|M.ulcerans_Agy99 ----------GLGGDGGSAGALSIS-AGGAGGNGGTG----------LSG
Mb1121|M.bovis_AF2122/97 ----------GNGGAGGAAGLFGDAGAGGNGGKGGAGGAAFSINFTAGDG
Rv1091|M.tuberculosis_H37Rv ----------GNGGAGGAAGLFGDAGAGGNGGKGGAGGAAFSINFTAGDG
Mflv_5091|M.gilvum_PYR-GCK -----AVGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----AVGAAG
Mvan_1264|M.vanbaalenii_PYR-1 -----AVGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----AIGTAG
MSMEG_0868|M.smegmatis_MC2_155 AGPNVTVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANG
TH_3810|M.thermoresistible__bu ------------NPDGGTPGAHG---------------------------
MAB_4284c|M.abscessus_ATCC_199 -----------QRNTTNINDSFNTDRSTNIGSGNTTN-------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ---------DAESPTVVIEKLFLPEDSEPRRRPVLLVG------------
MMAR_2969|M.marinum_M GSP------GSGGNGGAGGLFGAGGAGGNGAPD----------VGGGSP-
MUL_1339|M.ulcerans_Agy99 FG-------GAGGAGGNAGLYGHGGGGGAGGTG----------TGMGVDN
Mb1121|M.bovis_AF2122/97 GAG------GAGGSGGHALLWGAGGAGGNGGSG----------GTGGAGG
Rv1091|M.tuberculosis_H37Rv GAG------GAGGSGGHALLWGAGGAGGNGGSG----------GTGGAGG
Mflv_5091|M.gilvum_PYR-GCK -------AAGTVGTAGATGGTGTGANGGAGGVG-----GVGGTGAAGAAG
Mvan_1264|M.vanbaalenii_PYR-1 -------VAGAAGTAGATGGTGVGGNGGAGQAG-----GIGGTGAAGAAG
MSMEG_0868|M.smegmatis_MC2_155 GTVDGHAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATG
TH_3810|M.thermoresistible__bu ---------ESHTPGVYTDRQGEDGEDGTG--------------------
MAB_4284c|M.abscessus_ATCC_199 ---------TEIGSHNQANIGTSTSAGGSAAVG-----------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ---------SGLAVVGISAVLALEIALAIGIRT-----------------
MMAR_2969|M.marinum_M ---------GSGGNGGAG----------------------GLFFGDGGAG
MUL_1339|M.ulcerans_Agy99 DGI-----GGAGGAGGAG----------------------GWLIGTGGTG
Mb1121|M.bovis_AF2122/97 STAGAGGNGGAGGGGGTG----------------------GLLFGNGGAG
Rv1091|M.tuberculosis_H37Rv STAGAGGNGGAGGGGGTG----------------------GLLFGNGGAG
Mflv_5091|M.gilvum_PYR-GCK GAGGLGETGTTGGAGGVG--------------------GQGTAGGTGGVG
Mvan_1264|M.vanbaalenii_PYR-1 QAGTAGETGVTGGVGGIG--------------------GQGTEGGTGGVG
MSMEG_0868|M.smegmatis_MC2_155 GDGGHSTGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAG
TH_3810|M.thermoresistible__bu --------TGIGGRGGNG----------------------GSSSGTHPMA
MAB_4284c|M.abscessus_ATCC_199 --------GNAGLAGNAG------------------------LAGNAGLA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 -------TGTVALQPTPN---------------------QHLIVPTEQAP
MMAR_2969|M.marinum_M GN------------------------------------------------
MUL_1339|M.ulcerans_Agy99 GT------------------------------------------------
Mb1121|M.bovis_AF2122/97 GHGAAAGNGLA---------------------------------------
Rv1091|M.tuberculosis_H37Rv GHGAAAGNGLA---------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GIGGAG----------STGAVGG-------VGGKG----IQGGQG-----
Mvan_1264|M.vanbaalenii_PYR-1 GVGGVG----------ATGGAGG-------VGGKG----IQGGQG-----
MSMEG_0868|M.smegmatis_MC2_155 GMGEIYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGG
TH_3810|M.thermoresistible__bu ED------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GNAG----------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 APPP----------------------------------------------
MMAR_2969|M.marinum_M -----------GAPNVG--GGSPGA-------------------------
MUL_1339|M.ulcerans_Agy99 -----------GGFGDGPLGGQGGD-------------------------
Mb1121|M.bovis_AF2122/97 ---AGNGVSSSGGGGAGGTGGAGGD-------------------------
Rv1091|M.tuberculosis_H37Rv ---AGNGVSSSGGGGAGGTGGAGGD-------------------------
Mflv_5091|M.gilvum_PYR-GCK --------LQGGKGGDGGAGGKGGDADSMGS------------------A
Mvan_1264|M.vanbaalenii_PYR-1 --------LQGGQGGDGGTGGTGGDATSMGE------------------A
MSMEG_0868|M.smegmatis_MC2_155 KASGTAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAA
TH_3810|M.thermoresistible__bu -----------GEHVKALDGRPGLD-------------------------
MAB_4284c|M.abscessus_ATCC_199 ---------LAGNAGLAGNAGLAGN-------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ----------VQASAPQPKISVPEP-------------------------
MMAR_2969|M.marinum_M ------GGNG----------------------------------------
MUL_1339|M.ulcerans_Agy99 ------GGNAGLFGVGGDGG------------------------------
Mb1121|M.bovis_AF2122/97 ------GGAGGAGGNARLWG------------------------------
Rv1091|M.tuberculosis_H37Rv ------GGAGGAGGNARLWG------------------------------
Mflv_5091|M.gilvum_PYR-GCK GATGGKGGNGGNGGRGGLFG---------------KGGNAGNGAD-----
Mvan_1264|M.vanbaalenii_PYR-1 GATGGKGGNGGNGGRGSLFG---------------RGGNAGNGGN-----
MSMEG_0868|M.smegmatis_MC2_155 SANGAVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MMAR_2969|M.marinum_M -----------------GDAGLFG----AGG-AGGRGGNN----------
MUL_1339|M.ulcerans_Agy99 ----------------LGGTGFFG----AGG-AGGAAGNAGL--------
Mb1121|M.bovis_AF2122/97 ----------------VGGAGGAGGDGGAGG-AGGKGGSG----------
Rv1091|M.tuberculosis_H37Rv ----------------VGGAGGAGGDGGAGG-AGGKGGSG----------
Mflv_5091|M.gilvum_PYR-GCK -----------------GGTGGAGGAGGTGG-TGGAGGTGG---------
Mvan_1264|M.vanbaalenii_PYR-1 -----------------GGTGGNGGNGGTGG-TGGNGGTGG---------
MSMEG_0868|M.smegmatis_MC2_155 YDPNGPAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANG
TH_3810|M.thermoresistible__bu ---------------------------------GGNGSHG----------
MAB_4284c|M.abscessus_ATCC_199 -----------------AGLAGNAGLAGNAGLAGNAGLAGNAG-------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ----------------VAAPKPLSPPVAAPLPAAPPPAAPP---------
MMAR_2969|M.marinum_M --------LANPATDGGAG----GAG--GNGGAGG------LFAGAGGPG
MUL_1339|M.ulcerans_Agy99 --------ISGTGDVGGQG----GVGGFGEGGAGGDGGGA-GLIGNGGSG
Mb1121|M.bovis_AF2122/97 --------LSGNANGGAGG----DSGRGGTGGAGGEGGAAGLLVGTGGHG
Rv1091|M.tuberculosis_H37Rv --------LSGNANGGAGG----DSGRGGTGGAGGEGGAAGLLVGTGGHG
Mflv_5091|M.gilvum_PYR-GCK --------TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTG
Mvan_1264|M.vanbaalenii_PYR-1 --------TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTG
MSMEG_0868|M.smegmatis_MC2_155 QHSTGQTDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHG
TH_3810|M.thermoresistible__bu ----------GNGGHGGRG------GFLGIGGSGG----------WGGHG
MAB_4284c|M.abscessus_ATCC_199 --------LAGNAGLAGNAGLAGNAGLAGNAGLAGNAG----LAGNAGLA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------LPEAPPIPAAPPVVPVPVVVPPVPVPVPVRIPVPDPVSPPQL
MMAR_2969|M.marinum_M GQGGD-------------------NQNTNT----GPGGVGGAGGDAG---
MUL_1339|M.ulcerans_Agy99 GTGG--------------------NAVGNS----GVGGHGGAGGRGGR--
Mb1121|M.bovis_AF2122/97 GDGGAGGAAVKGGDGGAAAGTGIAGAGGRG----GAGGSGGSGGDGGGGA
Rv1091|M.tuberculosis_H37Rv GDGGAGGAAVKGGDGGAAAGTGIAGAGGRG----GAGGSGGSGGDGGGGA
Mflv_5091|M.gilvum_PYR-GCK GTGGKGGTG------------GTGGAGGTG----GDGGTGGTGGTGGTG-
Mvan_1264|M.vanbaalenii_PYR-1 GTGGKGGTG------------GTGGDGGTG----GTGGTGGTGGTGGTG-
MSMEG_0868|M.smegmatis_MC2_155 GDGGRGGDG------------ALGGNGGTGGVGLGNGGKGGNGGNGGNGG
TH_3810|M.thermoresistible__bu GNGGD------------------------------TDADGGNGGDGGNG-
MAB_4284c|M.abscessus_ATCC_199 GNAGLAG-----------------NAGLAG-----NAGLAGNAGLAGNAA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 LAPPRLSVP---------------QPVQPPVRVPQPPSPPQVGGTVPQS-
MMAR_2969|M.marinum_M ------LFS-GAIGGAGGSAG----------RSVGTIGSVGG----AGGN
MUL_1339|M.ulcerans_Agy99 ------LYGNGGVGGNGGFSGP---------ITAGGAGGTGG----TGGS
Mb1121|M.bovis_AF2122/97 AGPAGWLFGDGGAGGNGGAAAAG--------GAGGQAGGGGG----NGGN
Rv1091|M.tuberculosis_H37Rv AGPAGWLFGDGGAGGNGGAAAAG--------GAGGQAGGGGG----NGGN
Mflv_5091|M.gilvum_PYR-GCK --------GTGGTGGTGGAG-----------DGTGGTGGTGG----TGGQ
Mvan_1264|M.vanbaalenii_PYR-1 --------GTGGTGGTGGAG-----------DGLGGTGGTGG----TGGF
MSMEG_0868|M.smegmatis_MC2_155 TYVDPSHTGAGGNGGNGGAGRIRVNNGTATGTATGGNGGNGGNGDADGHR
TH_3810|M.thermoresistible__bu --------GSAGRGGTGGLR--------------GVFGINGG-----NGR
MAB_4284c|M.abscessus_ATCC_199 VAGNAAVAGNAAVAGNAAVGGVLN---------TGVSGAIGG-----SSH
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ------PPQHQTPPGEGTPPK------------PDGPGNYGG------GH
MMAR_2969|M.marinum_M GGLFGTGG-----------------AGGSGGQDGYNYGGNG---------
MUL_1339|M.ulcerans_Agy99 AGLPGDGG-----------------AGGAGGASGFAGGGTGGI-------
Mb1121|M.bovis_AF2122/97 GGNGGNGG-----------------NGGNGATGGWLYGNGG---------
Rv1091|M.tuberculosis_H37Rv GGNGGNGG-----------------NGGNGATGGWLYGNGG---------
Mflv_5091|M.gilvum_PYR-GCK GGQGGQGG-----------------TGGTGGQGG-LGGGGGTG-------
Mvan_1264|M.vanbaalenii_PYR-1 GGQGGQGG-----------------TGGTGGQGG-LGGVGGTG-------
MSMEG_0868|M.smegmatis_MC2_155 GGKGGDGGEALIRATVIGSNASGTATGGDGGNGGTLGATNGTGGAATIVA
TH_3810|M.thermoresistible__bu AGLGGRGX-----------------XXXGGGVGAAVRSGNG---------
MAB_4284c|M.abscessus_ATCC_199 VGGAINES-----------------LGGSGSVGGSTAVGGG---------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 VPTPGAGG-----------------SGGSGGGHVPTPGAGG---------
MMAR_2969|M.marinum_M ------------------GAGGLLFGVGGAGGA---------------AA
MUL_1339|M.ulcerans_Agy99 -----------------GGTGGLPFGAAGDGGN---------------GG
Mb1121|M.bovis_AF2122/97 -----------------AGGQGATAGAGGAGANGVSSTNGG-------GN
Rv1091|M.tuberculosis_H37Rv -----------------AGGQGATAGAGGAGANGVSSTNGGGTG----GN
Mflv_5091|M.gilvum_PYR-GCK ----------------GQGGTGGTGGQGGTGGTGGTGGTG--------GT
Mvan_1264|M.vanbaalenii_PYR-1 ----------------GTGGTGGTGGQGGTGGTGGTGGTG--------GT
MSMEG_0868|M.smegmatis_MC2_155 YNVVQANPQASGTATDGHGGSGINGGHGGNGGQGTIEANGPSAVASGIGA
TH_3810|M.thermoresistible__bu -------------------------------------------------V
MAB_4284c|M.abscessus_ATCC_199 ------------------AHTGVGGGVSTGVGVG--------------SH
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ------------------------------------------------SG
MMAR_2969|M.marinum_M LSGAGNGGTGGAGG--LFFGVGGAGG---AAPLFG---------------
MUL_1339|M.ulcerans_Agy99 FGAGGRGGSGGAGGDAWLFGSGGSGGSGGAGAIND---------------
Mb1121|M.bovis_AF2122/97 GGIGGTGGSGGAGGNAGLLGVGGAGGHGASGGAGDRGGAGGTGFISSDGG
Rv1091|M.tuberculosis_H37Rv GGIGGTGGSGGAGGNAGLLGVGGAGGHGASGGAGDRGGAGGTGFISSDGG
Mflv_5091|M.gilvum_PYR-GCK GGAGGDGGLGGLGGFGGSGGTGGQGGLGGPGGSTGGAGGAGG--QAGTAG
Mvan_1264|M.vanbaalenii_PYR-1 GGAGGDGGLGGLGGFGGVGGTGGQGGQGGPGGSTGGAGGAGG--QAGVAG
MSMEG_0868|M.smegmatis_MC2_155 GGNGGDGIDGGLGGNGGDGVVNTTANAANPGSATGTATGGDGGKATGTAS
TH_3810|M.thermoresistible__bu FSGGGGTPSAGFGVPTTIQFPAG---------------------------
MAB_4284c|M.abscessus_ATCC_199 VGGGISESLGGSGSVGGSTAVGGGAHTGVGGGVST---------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 GSGGGHVPTPGTGGPGGTGGSGG---------------------------
MMAR_2969|M.marinum_M --------------GGTGGTGGAGGLLFGLGGAGGNAPVFG---------
MUL_1339|M.ulcerans_Agy99 --------------GGSGGAVGNGGRLFGDAGAGGSGGAGGTSFLDTVIV
Mb1121|M.bovis_AF2122/97 AGGDGG-------DGGNGGAGGTGGLLFGAGGNGGPGGSGGAADIGGNGG
Rv1091|M.tuberculosis_H37Rv AGGDGG-------DGGNGGAGGTGGLLFGAGGNGGPGGSGGAADIGGNGG
Mflv_5091|M.gilvum_PYR-GCK KGGLFG----GSGSAGKAGATGAAGASGGKGAQGATGAQGATG------A
Mvan_1264|M.vanbaalenii_PYR-1 KGGLFG----GSGSAGTAGVTGASGASGGKGAQGATGAQGATG------A
MSMEG_0868|M.smegmatis_MC2_155 QGGNGGPSWVQSGYGSTLGGNATGTATAGKGGEASNGGVAGNGGNALVMA
TH_3810|M.thermoresistible__bu --------------SCTSRAVSREGIMPSSRAASAR--------------
MAB_4284c|M.abscessus_ATCC_199 --------------GVGVGSHVGGGISESLGGSGSVGGSTAVG-------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ------------------GHVPTPGAGTPGGSGGGHLPFPG---------
MMAR_2969|M.marinum_M -------GGSGGTGGRAGLIGIGGAGGS--------------------SS
MUL_1339|M.ulcerans_Agy99 SSN----GGAAGNGGSAGLVGNGGAGGAGG-----------QGGLIVSAD
Mb1121|M.bovis_AF2122/97 AGNGGGTDGNGGNGGSGGGAGSGGDGGGAG-----------GNGAWLFGN
Rv1091|M.tuberculosis_H37Rv AGNGGGTDGNGGNGGSGGGAGSGGDGGGAG-----------GNGAWLFGN
Mflv_5091|M.gilvum_PYR-GCK QGATG-ATGAAGKAGATGAAGAAGAAGSAG-----------TTGAQGSAG
Mvan_1264|M.vanbaalenii_PYR-1 QGATG-ATGASGAQGSAGSAGSAGVAGSAG-----------TTGAQGSAG
MSMEG_0868|M.smegmatis_MC2_155 AGTTGVATGNTATGGDGGAATTAGATGGAGGFSNIAAIHGAITDSTAISG
TH_3810|M.thermoresistible__bu -------AGAACASSTSRSRRSFCCSRA----------------------
MAB_4284c|M.abscessus_ATCC_199 --------GGAHTGVGGGVNTGVGVGSHVG-------------------G
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 -------AGSTPGGSGGGHLPTPGAGTPGG--------------------
MMAR_2969|M.marinum_M VFAGGDGGAGGAGG---------TFIGFGG--------AGGDGGVS----
MUL_1339|M.ulcerans_Agy99 DNNGGAGGDGGGAG---------LLLGAGG--------AGGQGGLGGNTV
Mb1121|M.bovis_AF2122/97 GGAGGGGGKGGNGAGGGLGGGSFGLPGLNG--------SGGDGGDGGNGA
Rv1091|M.tuberculosis_H37Rv GGAGGGGGKGGNGAGGGLGGGSFGLPGLNG--------SGGDGGDGGNGA
Mflv_5091|M.gilvum_PYR-GCK TNGA-NGANGSQGAAG--KAGATGTTGATG--------AAGEDGDAGSGG
Mvan_1264|M.vanbaalenii_PYR-1 TNGA-NGANGSQGAAG--KAGATGTTGATG--------AAGDAGDPGSEA
MSMEG_0868|M.smegmatis_MC2_155 HGGAGNGGNGGKGADG--WVQAYDPAGPVGSKIANSSAVAGNGGDGGVNG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GISESLGGSGSVGG------------------------STAVGGGAHTSA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MMAR_2969|M.marinum_M ------GNGGAGGKAGL-----IGVGGNGGNGGNGG-----NGGAGGD--
MUL_1339|M.ulcerans_Agy99 DG----GNGGNGGNAAL-----IGDGGSGGAGGDGGSGDAGDGGAGGD--
Mb1121|M.bovis_AF2122/97 PGGVLYGNGGAGGQGSS-----GGIGGPGATGGAGG-----KGGDGGD--
Rv1091|M.tuberculosis_H37Rv PGGVLYGNGGAGGQGSS-----GGIGGPGATGGAGG-----KGGDGGD--
Mflv_5091|M.gilvum_PYR-GCK SG-INGGAGGAGG-----------AGGEGGEGGDGG-----KGGAGAE--
Mvan_1264|M.vanbaalenii_PYR-1 VD-INGGAGGAGG-----------AGGEGGEGGAGG-----AGGDGSE--
MSMEG_0868|M.smegmatis_MC2_155 TGGASGGDGGNGGNTSVWKSGGQTADGEHNTGGNGG-----NGGDGSEPG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 INDALGGSGSVGGSTAVG-------GGAHTSAINESMNSSINASHSSS--
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ------GLGGFGGGHAP--------APGGGLGGGGG--------------
MMAR_2969|M.marinum_M ---AQLIGIGGNGGNGGDGQLGGP----GTGGTGGTGG--TLLGLNGIDG
MUL_1339|M.ulcerans_Agy99 ---ARLVGSGGNGGNG--GFSATP----AAGGTGDAGG--AVFGSDGVAG
Mb1121|M.bovis_AF2122/97 ---AQLIGDGGNGGNGGAGGTGGTPGPGGPGGSGGLGG--LLFGQTGTAG
Rv1091|M.tuberculosis_H37Rv ---AQLIGDGGNGGNGGAGGTGGTPGPGGPGGSGGLGG--LLFGQTGTAG
Mflv_5091|M.gilvum_PYR-GCK ------GGAGGGGGAGGSGAGGAG----GAGGSGGSGGSGGSGGSGGAAG
Mvan_1264|M.vanbaalenii_PYR-1 ------GGAGGSGGAGGSGTGGAG----GAGGSGGSGGSGGAGGSGGAAG
MSMEG_0868|M.smegmatis_MC2_155 PGGNGAGGAGGNGGTGGTTAGGSGNG--GNGGNGGNGGADGTPGTAGTTG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------MNESFGSSMGSHGAAGTG-----FEAQGHAQGHASETAHTTLPG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ------HAPAPGGGLGGFGGGHSG------GGLGGLGGGHK---------
MMAR_2969|M.marinum_M LDGSA
MUL_1339|M.ulcerans_Agy99 LP---
Mb1121|M.bovis_AF2122/97 VSP--
Rv1091|M.tuberculosis_H37Rv VSP--
Mflv_5091|M.gilvum_PYR-GCK DSDD-
Mvan_1264|M.vanbaalenii_PYR-1 DSD--
MSMEG_0868|M.smegmatis_MC2_155 ANNP-
TH_3810|M.thermoresistible__bu -----
MAB_4284c|M.abscessus_ATCC_199 AEHH-
MLBr_01183|M.leprae_Br4923 -----
MAV_4827|M.avium_104 -----