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M. marinum M MMAR_2477 (aao_1)

annotation: D-amino acid oxidase Aao_1
coordinates: 3014471 - 3015583
length: 370

MTPGDRPRVVVIGAGVSGWTTAMVLAKRGWQVVVAADGFGIDAVSSASGAMWEWPPSRCGRYHDQAVLAR
YAGWAMRSYLRFAQLASDPGTGVGLRPAVYYFGRRIEDDPIEFAKMSEVKRFVPGFVHDPALIDRHGVNR
DSGVIDAYSYLAPTIDTDWYLAWLAREAKNAGVCVDRRRIFGPLINQENRLLTEYRAELIINCAGLGARE
LAEDTTVVPHRGALLRVLQERTATSRVTAAHVVANDAATDQQNLISIVPRGSDQLVLGGLVEPDRYDTEL
NLADYPPLRMMFDRCVEFLPALRSAAPDVIHPVRVGLRPFRRDGVRLEAQRGTRIVHNYGHGGAGISLSW
GCAQEVADLAYRIFARQGVA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_2477aao_1-100% (370)D-amino acid oxidase Aao_1
M. marinum MMMAR_1462-e-12862.88% (361) oxidoreductase
M. marinum MMMAR_2801aao1e-3334.51% (368) D-amino acid oxidase Aao

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1940caao3e-3333.70% (365) putative D-amino acid oxidase aao
M. gilvum PYR-GCK-----
M. tuberculosis H37RvRv1905caao2e-3233.42% (365) D-amino acid oxidase
M. leprae Br4923MLBr_02011aao8e-2932.14% (364) D-amino acid oxidase
M. abscessus ATCC 19977-----
M. avium 104MAV_2796-9e-3032.96% (361) FAD dependent oxidoreductase
M. smegmatis MC2 155-----
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_1659aao_10.098.65% (370) D-amino acid oxidase Aao_1
M. vanbaalenii PYR-1-----

CLUSTAL 2.0.9 multiple sequence alignment


MLBr_02011|M.leprae_Br4923        -MASNGQQIVVIGAGVSGLTSAVCLAEAGWPVQLWAAAMPQQTTSAVAGA
MAV_2796|M.avium_104              -MARN-QQIVVIGAGVSGLTSAICLAEAGWPVRVWADTMPADTTSAVAGA
Mb1940c|M.bovis_AF2122/97         -MAIGEQQVIVIGAGVSGLTSAICLAEAGWPVRVWAAALPQQTTSAVAGA
Rv1905c|M.tuberculosis_H37Rv      -MAIGEQQVIVIGAGVSGLTSAICLAEAGWPVRVWAAALPQQTTSAVAGA
MMAR_2477|M.marinum_M             MTPGDRPRVVVIGAGVSGWTTAMVLAKRGWQVVVAADGFGIDAVSSASGA
MUL_1659|M.ulcerans_Agy99         MTPGDRPRVVVIGAGVSGWTTAMVLAKRGWQVVVAADGFGIDAVSSASGA
                                    . .  :::******** *:*: **: ** * : *  :  ::.*:.:**

MLBr_02011|M.leprae_Br4923        VWAPP-------RPEERASTSLAWTGHSLQIFRELANDPSTGVRMAPALT
MAV_2796|M.avium_104              VWAPP-------RPAERAAETLRWTEHSLRVFTELARDPDSGVQLAPALA
Mb1940c|M.bovis_AF2122/97         VWGP--------RPKEPVAKVRGWIEQSLHVFRDLAKDPATGVRMTPALS
Rv1905c|M.tuberculosis_H37Rv      VWGP--------RPKEPVAKVRGWIEQSLHVFRDLAKDPATGVRMTPALS
MMAR_2477|M.marinum_M             MWEWPPSRCGRYHDQAVLARYAGWAMRSYLRFAQLASDPGTGVGLRPAVY
MUL_1659|M.ulcerans_Agy99         MWEWPLSRCGRYHDQAVLARYAGWAMRSYLRFAQLASDPGTGVGLRPAVY
                                  :*          :     :    *  :*   * :** ** :** : **: 

MLBr_02011|M.leprae_Br4923        VG------DLPGANAMGLAAKLIP------DLRPADLADLPDGFGAGFFG
MAV_2796|M.avium_104              VG------ELTASEAMSTAASLIP------ELRPADPADLPPGYRTGFHA
Mb1940c|M.bovis_AF2122/97         VG------DRIETGAMPPGLELIP------DVRPADPADVPGGFRAGFHA
Rv1905c|M.tuberculosis_H37Rv      VG------DRIETGAMPPGLELIP------DVRPADPADVPGGFRAGFHA
MMAR_2477|M.marinum_M             YFGRRIEDDPIEFAKMSEVKRFVPGFVHDPALIDRHGVNRDSGVIDAYSY
MUL_1659|M.ulcerans_Agy99         YFGRRIEDDPIEFAKMSEVKRFVPRFVHDPALIDRHGVNRDSGVIDAYSY
                                          :      *     ::*       :   . .:   *   .:  

MLBr_02011|M.leprae_Br4923        TMPMIDMPQYLDYLTARLAAAGCELETRSVR-------SLAEAADTAPII
MAV_2796|M.avium_104              TVPMIDMPHYLGYLTRRLTAAGGEIEEHRVG-------SLDEVADHADIV
Mb1940c|M.bovis_AF2122/97         TLPMIDMPQYLDCLTQRLAATGCEIETRPLR-------SLAEAAEAAPIV
Rv1905c|M.tuberculosis_H37Rv      TLPMIDMPQYLDCLTQRLAATGCEIETRPLR-------SLAEAAEAAPIV
MMAR_2477|M.marinum_M             LAPTIDTDWYLAWLAREAKNAGVCVDRRRIFGPLINQENRLLTEYRAELI
MUL_1659|M.ulcerans_Agy99         LAPTIDTDWYLAWLAREAKNAGVCVDRRRIFGPLINQENRLLTEYRAESI
                                    * **   **  *: .   :*  :: : :        .   .   *  :

MLBr_02011|M.leprae_Br4923        VNCTGLGAAALANDDTVRPLFG------QHVVLTNPGLQQLFLEVNNGSE
MAV_2796|M.avium_104              VNCAGLRAGALTGDDTVRPLFG------QHVVLTNPGVRQLFMELNDGPE
Mb1940c|M.bovis_AF2122/97         INCAGLGARELAGDATVWPRFG------QHVVLTNPGLEQLFIERTGGSE
Rv1905c|M.tuberculosis_H37Rv      INCAGLGARELAGDATVWPRFG------QHVVLTNPGLEQLFIERTGGSE
MMAR_2477|M.marinum_M             INCAGLGARELAEDTTVVPHRGALLRVLQERTATSRVTAAHVVANDAATD
MUL_1659|M.ulcerans_Agy99         INCAGLGARELAEDTTVVPHRGALLRVLQERTATSRVTAADVVANDAATD
                                  :**:** *  *: * ** *  *      *. . *.      .:    ..:

MLBr_02011|M.leprae_Br4923        WICYFPHPLR----VVCGGISIPGRWDTTP---DPAVTDRILQRCRRIEP
MAV_2796|M.avium_104              WTCYFPHPQR----VVCGGISIAGRWDTTA---DPAVTERILQRCRRIEP
Mb1940c|M.bovis_AF2122/97         WICYFAHPQR----VVCGGISIPGRWDTTP---EPEITERILQRCRRIQP
Rv1905c|M.tuberculosis_H37Rv      WICYFAHPQR----VVCGGISIPGRWDPTP---EPEITERILQRCRRIQP
MMAR_2477|M.marinum_M             QQNLISIVPRGSDQLVLGGLVEPDRYDTELNLADYPPLRMMFDRCVEFLP
MUL_1659|M.ulcerans_Agy99         QQNLISIVPRGSDQLVLGGLVEPDRYHTELNLADYPPLRMMFDRCVEFLP
                                      :.   *    :* **:  ..*:..     :      :::** .: *

MLBr_02011|M.leprae_Br4923        RLGEAA---VIETITGLRPDRPSPRVEVELSGSVRYIHNYGHSSSGVTLS
MAV_2796|M.avium_104              RLGEAE---VIEVITGLRPDRPSVRLQAEPLRRARCIHNYGHSSNGVTLS
Mb1940c|M.bovis_AF2122/97         RLAEAA---VIETITGLRPDRPSVRVEAEPIGRALCIHNYGHGGDGVTLS
Rv1905c|M.tuberculosis_H37Rv      RLAEAA---VIETITGLRPDRPSVRVEAEPIGRALCIHNYGHGGDGVTLS
MMAR_2477|M.marinum_M             ALRSAAPDVIHPVRVGLRPFRRD-GVRLEAQRGTRIVHNYGHGGAGISLS
MUL_1659|M.ulcerans_Agy99         ALRSAAPDVIHPVRVGLRPFRRD-GVRLEAQRGTRIVHNYGHGGAGISLS
                                   * .*    :  . .**** * .  :. *    .  :*****.. *::**

MLBr_02011|M.leprae_Br4923        WGCARDVVRLVSD--------
MAV_2796|M.avium_104              WGCARDVLALVDDAR------
Mb1940c|M.bovis_AF2122/97         WGCAREVVNLVGGG-------
Rv1905c|M.tuberculosis_H37Rv      WGCAREVVNLVGGG-------
MMAR_2477|M.marinum_M             WGCAQEVADLAYRIFARQGVA
MUL_1659|M.ulcerans_Agy99         WGCAQEVADLAYRIFARQGVA
                                  ****::*  *.