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RPLNQARALVIGAGVSGWTTALVLARCGWRVVVVADRFGIDPASMVTDVLWQWPPSVSDCHDNQTVLTRS VTWAQDSYTSFCRLARHSRTGVNARRAVFYFSHPVEEDRAEFAKMVEVERYVPGFVHDPALIDAHGVNPD ADVVDAYSYLALTIDTDWYLAWLAHEAEVAGVTAVQRRIRGPLLEQEQRLRAEYGAEVIVNCAGLGAREL ADDSTLDLHRCALLRIVNDACAARVTAAHVVGNNASANTQNKIFIVPLGVKRLLLGGLVEPGQYDTDLNF ANHPPLQDMLDRCTEFLPILRGAQLDDLDPVRVGLQPFRPGGVRLETQPHTRIVHNYGHGGAGATLSWGC AHEVADLAYELALHR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_1462 | - | - | 100% (366) | oxidoreductase |
| M. marinum M | MMAR_2477 | aao_1 | e-128 | 62.88% (361) | D-amino acid oxidase Aao_1 |
| M. marinum M | MMAR_2801 | aao | 4e-23 | 31.62% (370) | D-amino acid oxidase Aao |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1940c | aao | 9e-26 | 29.89% (368) | putative D-amino acid oxidase aao |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv1905c | aao | 4e-25 | 29.62% (368) | D-amino acid oxidase |
| M. leprae Br4923 | MLBr_02011 | aao | 3e-23 | 30.14% (365) | D-amino acid oxidase |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. avium 104 | MAV_2796 | - | 3e-24 | 29.05% (358) | FAD dependent oxidoreductase |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_1659 | aao_1 | 1e-124 | 61.77% (361) | D-amino acid oxidase Aao_1 |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
MLBr_02011|M.leprae_Br4923 -MASNGQQIVVIGAGVSGLTSAVCLAEAGWPVQLWAAAMPQQTTSAVAGA
MAV_2796|M.avium_104 -MARN-QQIVVIGAGVSGLTSAICLAEAGWPVRVWADTMPADTTSAVAGA
Mb1940c|M.bovis_AF2122/97 -MAIGEQQVIVIGAGVSGLTSAICLAEAGWPVRVWAAALPQQTTSAVAGA
Rv1905c|M.tuberculosis_H37Rv -MAIGEQQVIVIGAGVSGLTSAICLAEAGWPVRVWAAALPQQTTSAVAGA
MMAR_1462|M.marinum_M MRPLNQARALVIGAGVSGWTTALVLARCGWRVVVVADRFGIDPASMVTDV
MUL_1659|M.ulcerans_Agy99 MTPGDRPRVVVIGAGVSGWTTAMVLAKRGWQVVVAADGFGIDAVSSASGA
. . : :******** *:*: **. ** * : * : :..* .:..
MLBr_02011|M.leprae_Br4923 VWAPP-------RPEERASTSLAWTGHSLQIFRELANDPSTGVRMAPALT
MAV_2796|M.avium_104 VWAPP-------RPAERAAETLRWTEHSLRVFTELARDPDSGVQLAPALA
Mb1940c|M.bovis_AF2122/97 VWGP--------RPKEPVAKVRGWIEQSLHVFRDLAKDPATGVRMTPALS
Rv1905c|M.tuberculosis_H37Rv VWGP--------RPKEPVAKVRGWIEQSLHVFRDLAKDPATGVRMTPALS
MMAR_1462|M.marinum_M LWQWPPSVSDCHDNQTVLTRSVTWAQDSYTSFCRLARHSRTGVNARRAVF
MUL_1659|M.ulcerans_Agy99 MWEWPLSRCGRYHDQAVLARYAGWAMRSYLRFAQLASDPGTGVGLRPAVY
:* : * * * ** .. :** *:
MLBr_02011|M.leprae_Br4923 VG------DLPGANAMGLAAKLIP------DLRPADLADLPDGFGAGFFG
MAV_2796|M.avium_104 VG------ELTASEAMSTAASLIP------ELRPADPADLPPGYRTGFHA
Mb1940c|M.bovis_AF2122/97 VG------DRIETGAMPPGLELIP------DVRPADPADVPGGFRAGFHA
Rv1905c|M.tuberculosis_H37Rv VG------DRIETGAMPPGLELIP------DVRPADPADVPGGFRAGFHA
MMAR_1462|M.marinum_M YFSHPVEEDRAEFAKMVEVERYVPGFVHDPALIDAHGVNPDADVVDAYSY
MUL_1659|M.ulcerans_Agy99 YFGRRIEDDPIEFAKMSEVKRFVPRFVHDPALIDRHGVNRDSGVIDAYSY
: * :* : . .: . .:
MLBr_02011|M.leprae_Br4923 TMPMIDMPQYLDYLTARLAAAGCELETRSVR-------SLAEAADTAPII
MAV_2796|M.avium_104 TVPMIDMPHYLGYLTRRLTAAGGEIEEHRVG-------SLDEVADHADIV
Mb1940c|M.bovis_AF2122/97 TLPMIDMPQYLDCLTQRLAATGCEIETRPLR-------SLAEAAEAAPIV
Rv1905c|M.tuberculosis_H37Rv TLPMIDMPQYLDCLTQRLAATGCEIETRPLR-------SLAEAAEAAPIV
MMAR_1462|M.marinum_M LALTIDTDWYLAWLAHEAEVAGVTAVQRRIRGPLLEQEQRLRAEYGAEVI
MUL_1659|M.ulcerans_Agy99 LAPTIDTDWYLAWLAREAKNAGVCVDRRRIFGPLINQENRLLTEYRAESI
** ** *: . :* : : . . * :
MLBr_02011|M.leprae_Br4923 VNCTGLGAAALANDDTVRPLFGQHVVLTNP-------GLQQLFLEVNNGS
MAV_2796|M.avium_104 VNCAGLRAGALTGDDTVRPLFGQHVVLTNP-------GVRQLFMELNDGP
Mb1940c|M.bovis_AF2122/97 INCAGLGARELAGDATVWPRFGQHVVLTNP-------GLEQLFIERTGGS
Rv1905c|M.tuberculosis_H37Rv INCAGLGARELAGDATVWPRFGQHVVLTNP-------GLEQLFIERTGGS
MMAR_1462|M.marinum_M VNCAGLGARELADDSTLDLHRCALLRIVND-ACAARVTAAHVVGNNASAN
MUL_1659|M.ulcerans_Agy99 INCAGLGARELAEDTTVVPHRGALLRVLQERTATSRVTAADVVANDAATD
:**:** * *: * *: : : : .:. :
MLBr_02011|M.leprae_Br4923 EWICYFPHP---LRVVCGGISIPGRWDTTP---DPAVTDRILQRCRRIEP
MAV_2796|M.avium_104 EWTCYFPHP---QRVVCGGISIAGRWDTTA---DPAVTERILQRCRRIEP
Mb1940c|M.bovis_AF2122/97 EWICYFAHP---QRVVCGGISIPGRWDTTP---EPEITERILQRCRRIQP
Rv1905c|M.tuberculosis_H37Rv EWICYFAHP---QRVVCGGISIPGRWDPTP---EPEITERILQRCRRIQP
MMAR_1462|M.marinum_M TQNKIFIVPLGVKRLLLGGLVEPGQYDTDLNFANHPPLQDMLDRCTEFLP
MUL_1659|M.ulcerans_Agy99 QQNLISIVPRGSDQLVLGGLVEPDRYHTELNLADYPPLRMMFDRCVEFLP
* ::: **: ..::.. : :::** .: *
MLBr_02011|M.leprae_Br4923 RLG---EAAVIETITGLRPDRPSPRVEVELSGSVRYIHNYGHSSSGVTLS
MAV_2796|M.avium_104 RLG---EAEVIEVITGLRPDRPSVRLQAEPLRRARCIHNYGHSSNGVTLS
Mb1940c|M.bovis_AF2122/97 RLA---EAAVIETITGLRPDRPSVRVEAEPIGRALCIHNYGHGGDGVTLS
Rv1905c|M.tuberculosis_H37Rv RLA---EAAVIETITGLRPDRPSVRVEAEPIGRALCIHNYGHGGDGVTLS
MMAR_1462|M.marinum_M ILRGAQLDDLDPVRVGLQPFRPG-GVRLETQPHTRIVHNYGHGGAGATLS
MUL_1659|M.ulcerans_Agy99 ALRSAAPDVIHPVRVGLRPFRRD-GVRLEAQRGTRIVHNYGHGGAGISLS
* : . .**:* * . :. * . :*****.. * :**
MLBr_02011|M.leprae_Br4923 WGCARDVVRLVSD--------
MAV_2796|M.avium_104 WGCARDVLALVDDAR------
Mb1940c|M.bovis_AF2122/97 WGCAREVVNLVGGG-------
Rv1905c|M.tuberculosis_H37Rv WGCAREVVNLVGGG-------
MMAR_1462|M.marinum_M WGCAHEVADLAYELALHR---
MUL_1659|M.ulcerans_Agy99 WGCAQEVADLAYRIFARQGVA
****::* *.