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MASNGQQIVVIGAGVSGLTSAVCLAEAGWPVQLWAAAMPQQTTSAVAGAVWAPPRPEERASTSLAWTGHS LQIFRELANDPSTGVRMAPALTVGDLPGANAMGLAAKLIPDLRPADLADLPDGFGAGFFGTMPMIDMPQY LDYLTARLAAAGCELETRSVRSLAEAADTAPIIVNCTGLGAAALANDDTVRPLFGQHVVLTNPGLQQLFL EVNNGSEWICYFPHPLRVVCGGISIPGRWDTTPDPAVTDRILQRCRRIEPRLGEAAVIETITGLRPDRPS PRVEVELSGSVRYIHNYGHSSSGVTLSWGCARDVVRLVSD
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. leprae Br4923 | MLBr_02011 | aao | - | 100% (320) | D-amino acid oxidase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1940c | aao | 1e-132 | 71.38% (318) | putative D-amino acid oxidase aao |
| M. gilvum PYR-GCK | Mflv_0197 | - | 2e-06 | 27.13% (328) | glycine oxidase ThiO |
| M. tuberculosis H37Rv | Rv1905c | aao | 1e-131 | 71.07% (318) | D-amino acid oxidase |
| M. abscessus ATCC 19977 | MAB_4218c | - | 6e-06 | 26.35% (334) | thiamine biosynthesis oxidoreductase ThiO |
| M. marinum M | MMAR_2801 | aao | 1e-120 | 65.51% (316) | D-amino acid oxidase Aao |
| M. avium 104 | MAV_2796 | - | 1e-134 | 72.50% (320) | FAD dependent oxidoreductase |
| M. smegmatis MC2 155 | MSMEG_0791 | thiO | 2e-07 | 26.51% (332) | glycine oxidase ThiO |
| M. thermoresistible (build 8) | TH_2312 | - | 3e-06 | 27.08% (325) | POSSIBLE THIAMINE BIOSYNTHESIS OXIDOREDUCTASE THIO |
| M. ulcerans Agy99 | MUL_2926 | aao | 1e-121 | 65.82% (316) | D-amino acid oxidase Aao |
| M. vanbaalenii PYR-1 | Mvan_0708 | - | 9e-06 | 26.48% (321) | glycine oxidase ThiO |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0197|M.gilvum_PYR-GCK -----MPAHTRGRLAVIGGGVIGLAVARRAALDGWATRVHRTEH--PGAS
Mvan_0708|M.vanbaalenii_PYR-1 -----MPAHTRGTLAVIGGGVIGLSVARRALQDGWAVRVHRAER--AGAS
MSMEG_0791|M.smegmatis_MC2_155 --------MTR-TVAVIGGGVIGLSVARRAALDGWTVRLHCTTE--RGAS
TH_2312|M.thermoresistible__bu ---MSDVIGSDRTVAVVGGGVIGLAVARRAALAGWQVRVHRSEE--RGAS
MAB_4218c|M.abscessus_ATCC_199 -----MMSSQKGSVAVIGGGVIGLSVAREAARTGWRVVIHDDGA--KGPS
MLBr_02011|M.leprae_Br4923 ------MASNGQQIVVIGAGVSGLTSAVCLAEAGWPVQLWAAAMPQQTTS
MAV_2796|M.avium_104 ------MARN-QQIVVIGAGVSGLTSAICLAEAGWPVRVWADTMPADTTS
Mb1940c|M.bovis_AF2122/97 ------MAIGEQQVIVIGAGVSGLTSAICLAEAGWPVRVWAAALPQQTTS
Rv1905c|M.tuberculosis_H37Rv ------MAIGEQQVIVIGAGVSGLTSAICLAEAGWPVRVWAAALPQQTTS
MMAR_2801|M.marinum_M MGSGRTAASDAQQVVVIGAGVSGLTSALCLAEAGWPVRVWTDLLPRQTTS
MUL_2926|M.ulcerans_Agy99 MGSGRTAASDAQQVVVIGAGISGLTSALCLAEAGWPVRVWIDLLPRQTTS
: *:*.*: **: * ** . : .*
Mflv_0197|M.gilvum_PYR-GCK WVAGGMLAPHSEGWPGEEQLLTLGLESLRLWHEQFLGSLPAQVVTARESL
Mvan_0708|M.vanbaalenii_PYR-1 WVAGGMLAPHSEGWPGEERLLQIGLESLRLWREGFLDGLPPEVVTARESL
MSMEG_0791|M.smegmatis_MC2_155 WVAGGMLAPHSEGWPGEEQLLQLGLESLRLWHSGFLDGLPEKVVTARESL
TH_2312|M.thermoresistible__bu WVAGGMLAPHSEGWPGEEHLLRLGLASLNLWRNGFLDGLPPEVVTARESL
MAB_4218c|M.abscessus_ATCC_199 WVAGGMLAPYSEAWPGEDELLELGIESLGIWRDGFIDDVENPVITARGSL
MLBr_02011|M.leprae_Br4923 AVAGAVWAPPRPEER-ASTSLAWTGHSLQIFRELAND----PSTGVRMAP
MAV_2796|M.avium_104 AVAGAVWAPPRPAER-AAETLRWTEHSLRVFTELARD----PDSGVQLAP
Mb1940c|M.bovis_AF2122/97 AVAGAVWGP-RPKEP-VAKVRGWIEQSLHVFRDLAKD----PATGVRMTP
Rv1905c|M.tuberculosis_H37Rv AVAGAVWGP-RPKEP-VAKVRGWIEQSLHVFRDLAKD----PATGVRMTP
MMAR_2801|M.marinum_M AVAGAVWRP-RFVEP-VVKTRKWAEQSLHRFRELADD----PTSGVQLMP
MUL_2926|M.ulcerans_Agy99 AVAGAVWRP-RFVEP-VVKARKWAEQSLHRFRELADD----PTSGVQLMP
***.: * ** : . . .:
Mflv_0197|M.gilvum_PYR-GCK VVAVDQADAADLRTVAAWLCAQGHPVTPTTSARDMEPLLAQGIRHGFSAD
Mvan_0708|M.vanbaalenii_PYR-1 VVAVDPADAADLKTVAAWLSGQGHPVTLTTSAREVEPLLAQGIRHGFRAE
MSMEG_0791|M.smegmatis_MC2_155 VVAVDRADAADLRTVAEWLAAQGHPVEFTTAARDVEPLLAQGIRHGFRAT
TH_2312|M.thermoresistible__bu VVAVDRADVADLQTVGSWLAGQGHPVTFTTSARDVEPLLAQGIRHGFIAD
MAB_4218c|M.abscessus_ATCC_199 TVAVDTADVGELRTMTGWLAARGHPVTEIANARDVEPMLAQNVRRGFTAP
MLBr_02011|M.leprae_Br4923 ALTVGDLPGANAMGLAAKLIPDLRPADLADLPDGFGAGFFGTMP-----M
MAV_2796|M.avium_104 ALAVGELTASEAMSTAASLIPELRPADPADLPPGYRTGFHATVP-----M
Mb1940c|M.bovis_AF2122/97 ALSVGDRIETGAMPPGLELIPDVRPADPADVPGGFRAGFHATLP-----M
Rv1905c|M.tuberculosis_H37Rv ALSVGDRIETGAMPPGLELIPDVRPADPADVPGGFRAGFHATLP-----M
MMAR_2801|M.marinum_M AISVGEIAEVDVTASGEDMIPGLRPVADTDVPDGFPTATAATLP-----M
MUL_2926|M.ulcerans_Agy99 AISVGEIAEVDVTASGEDMIPGLRPVADTDVPDGFPAATAATLP-----M
.::*. : :*. . . :
Mflv_0197|M.gilvum_PYR-GCK TELAVDNRAVVAALAEQCERLDVRWAPPVDSLAETADADAVVIANGIDAP
Mvan_0708|M.vanbaalenii_PYR-1 TELAVDNRAVVAALAAECERLGVEWAPPVAALTDAGPADTVVIANGIDAP
MSMEG_0791|M.smegmatis_MC2_155 TELAVDNRGVVDALAAHCERLAVRWAGQVDDLADV-DADAVVIANGIDAP
TH_2312|M.thermoresistible__bu TELAVDNRAVVEALRAHCDRLGVQWAPPVTDLAEV-DAPVRVIANGLDAP
MAB_4218c|M.abscessus_ATCC_199 EELSVDNRKVLQALTAECEALGVGRGPAAVHTRDV-DADQVVIANGVQAA
MLBr_02011|M.leprae_Br4923 IDMPQYLDYLTARLAAAGCELETRSVRSLAEAADT--APIIVNCTGLGAA
MAV_2796|M.avium_104 IDMPHYLGYLTRRLTAAGGEIEEHRVGSLDEVADH--ADIVVNCAGLRAG
Mb1940c|M.bovis_AF2122/97 IDMPQYLDCLTQRLAATGCEIETRPLRSLAEAAEA--APIVINCAGLGAR
Rv1905c|M.tuberculosis_H37Rv IDMPQYLDCLTQRLAATGCEIETRPLRSLAEAAEA--APIVINCAGLGAR
MMAR_2801|M.marinum_M IDMPRYLDYLTTRLAAAGCEIEIHPVRSLTEAAQS--APIVINCSGLGAR
MUL_2926|M.ulcerans_Agy99 IDMPRYLDYLTTRLAAAGCEIEIHPVRSLTEAAQS--APIVINCSGLGAR
::. : * : : * : . *: *
Mflv_0197|M.gilvum_PYR-GCK ALWPGLPVRPVKGEVLRLRWRRGCLPVPRRVVRARVRGRQVYVVPRPDGV
Mvan_0708|M.vanbaalenii_PYR-1 TLWPGLPVRPVKGEVLRLRWRRGCLPVPQRVVRARVHGRQVYVVPRADGV
MSMEG_0791|M.smegmatis_MC2_155 RLWPDLPVRPVKGEVLRLRWRKGCMPVPQRVIRARVHGRQVYLVPRADGV
TH_2312|M.thermoresistible__bu ALWPGLPIRPVKGEVLRLRWRRGCMPVPQRVIRARVHGRQVYLVPRADGL
MAB_4218c|M.abscessus_ATCC_199 ALA-GLPVRPVKGEVLRLRQRPGAMPPPANVIRARVHGRHVYLVPRADGV
MLBr_02011|M.leprae_Br4923 ALANDDTVRPLFGQHVVLTNPG----LQQLFLEVNNGSEWICYFPHPLRV
MAV_2796|M.avium_104 ALTGDDTVRPLFGQHVVLTNPG----VRQLFMELNDGPEWTCYFPHPQRV
Mb1940c|M.bovis_AF2122/97 ELAGDATVWPRFGQHVVLTNPG----LEQLFIERTGGSEWICYFAHPQRV
Rv1905c|M.tuberculosis_H37Rv ELAGDATVWPRFGQHVVLTNPG----LEQLFIERTGGSEWICYFAHPQRV
MMAR_2801|M.marinum_M ELAGDDTLRPRFGQHVVLANPG----LDQLFMQLGDGPEWICYFPHPHRV
MUL_2926|M.ulcerans_Agy99 ELAGDDTLRPRFGQHVVLANPG----LDQLFMQLGDGPEWICYFPHPHRV
* . .: * *: : * .:. . ..:. :
Mflv_0197|M.gilvum_PYR-GCK VVGATQYEHGRDTAPTVGGVRDLLDDACAVMPGLGEYEFAEAAAGLRPMT
Mvan_0708|M.vanbaalenii_PYR-1 VVGATQYEHGRDTAPTVSGVRDLLDDACAVMPALGEYEFAEAAAGLRPMT
MSMEG_0791|M.smegmatis_MC2_155 VVGATQYEHGRDTAPVVSGVRDLLEDACAVMPALGEYELAEIAAGLRPMT
TH_2312|M.thermoresistible__bu VVGATQYEHGRDTAPSVTGVRDLLDDSCAVVPALGEYELAECAAGLRPMT
MAB_4218c|M.abscessus_ATCC_199 VVGATQYEHGHDTAPAVAGVRDLLDDACALLPCLGEYEFAECAAGLRPMT
MLBr_02011|M.leprae_Br4923 VCGGISIPGRWDTTPDPAVTDRILQRCRRIEPRLGEAAVIETITGLRPDR
MAV_2796|M.avium_104 VCGGISIAGRWDTTADPAVTERILQRCRRIEPRLGEAEVIEVITGLRPDR
Mb1940c|M.bovis_AF2122/97 VCGGISIPGRWDTTPEPEITERILQRCRRIQPRLAEAAVIETITGLRPDR
Rv1905c|M.tuberculosis_H37Rv VCGGISIPGRWDPTPEPEITERILQRCRRIQPRLAEAAVIETITGLRPDR
MMAR_2801|M.marinum_M VCGGISILDRWDTTADPQVTDRILRDCRRVEPRLADAPVIETITGLRPDR
MUL_2926|M.ulcerans_Agy99 VCGGISILDRWDTTADPQVTDRILRDCRRIEPRLADAPVIETITGLRPDR
* *. . *.:. . :* . : * *.: . * :****
Mflv_0197|M.gilvum_PYR-GCK PDN-LPLVGRLDERTLVAAGHGRSGFLLAPWTVEKIAAELEGAMVMEVAE
Mvan_0708|M.vanbaalenii_PYR-1 PDN-LPLVGRLDERTLVAAGHGRSGFLLAPWTAESIAAELEGALVR----
MSMEG_0791|M.smegmatis_MC2_155 PDG-LPVVERVDERTVVAVGHGRNGFLLAPWTAERVAAELEVGVGAK---
TH_2312|M.thermoresistible__bu PDN-LPIVGRLDDRTLVAAGHGRSGFLLAPWTAEAILAELDGAPLPEAEL
MAB_4218c|M.abscessus_ATCC_199 DDN-LPMVGRIDERVVVAAGHGRSGFLLAPWTAKTIGAVLDGGESPAAVD
MLBr_02011|M.leprae_Br4923 PSPRVEVELSGSVRYIHNYGHSSSGVTLS-WGCARDVVRLVSD-------
MAV_2796|M.avium_104 PSVRLQAEPLRRARCIHNYGHSSNGVTLS-WGCARDVLALVDDAR-----
Mb1940c|M.bovis_AF2122/97 PSVRVEAEPIGRALCIHNYGHGGDGVTLS-WGCAREVVNLVGGG------
Rv1905c|M.tuberculosis_H37Rv PSVRVEAEPIGRALCIHNYGHGGDGVTLS-WGCAREVVNLVGGG------
MMAR_2801|M.marinum_M PSVRVEVEQIGATRCIHNYGHGGDGVTLS-WGCALDVARLAGLDC-----
MUL_2926|M.ulcerans_Agy99 PSVRVEVEQIGTTRCIHNYGHGGDGVTLS-WGCALDVARLAGLDC-----
. : : **. .*. *: * *
Mflv_0197|M.gilvum_PYR-GCK -------------
Mvan_0708|M.vanbaalenii_PYR-1 -------------
MSMEG_0791|M.smegmatis_MC2_155 -------------
TH_2312|M.thermoresistible__bu VGAR---------
MAB_4218c|M.abscessus_ATCC_199 PRRFEKAHSQEAR
MLBr_02011|M.leprae_Br4923 -------------
MAV_2796|M.avium_104 -------------
Mb1940c|M.bovis_AF2122/97 -------------
Rv1905c|M.tuberculosis_H37Rv -------------
MMAR_2801|M.marinum_M -------------
MUL_2926|M.ulcerans_Agy99 -------------