For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MARNQQIVVIGAGVSGLTSAICLAEAGWPVRVWADTMPADTTSAVAGAVWAPPRPAERAAETLRWTEHSL RVFTELARDPDSGVQLAPALAVGELTASEAMSTAASLIPELRPADPADLPPGYRTGFHATVPMIDMPHYL GYLTRRLTAAGGEIEEHRVGSLDEVADHADIVVNCAGLRAGALTGDDTVRPLFGQHVVLTNPGVRQLFME LNDGPEWTCYFPHPQRVVCGGISIAGRWDTTADPAVTERILQRCRRIEPRLGEAEVIEVITGLRPDRPSV RLQAEPLRRARCIHNYGHSSNGVTLSWGCARDVLALVDDAR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2796 | - | - | 100% (321) | FAD dependent oxidoreductase |
| M. avium 104 | MAV_4746 | thiO | 9e-07 | 28.27% (329) | glycine oxidase ThiO |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1940c | aao | 1e-124 | 68.05% (313) | putative D-amino acid oxidase aao |
| M. gilvum PYR-GCK | Mflv_0197 | - | 2e-10 | 29.82% (342) | glycine oxidase ThiO |
| M. tuberculosis H37Rv | Rv1905c | aao | 1e-123 | 67.73% (313) | D-amino acid oxidase |
| M. leprae Br4923 | MLBr_02011 | aao | 1e-135 | 72.50% (320) | D-amino acid oxidase |
| M. abscessus ATCC 19977 | MAB_4218c | - | 1e-05 | 27.54% (334) | thiamine biosynthesis oxidoreductase ThiO |
| M. marinum M | MMAR_2801 | aao | 1e-119 | 66.03% (312) | D-amino acid oxidase Aao |
| M. smegmatis MC2 155 | MSMEG_0791 | thiO | 2e-10 | 28.79% (330) | glycine oxidase ThiO |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_2926 | aao | 1e-118 | 65.38% (312) | D-amino acid oxidase Aao |
| M. vanbaalenii PYR-1 | Mvan_0708 | - | 5e-07 | 26.74% (344) | glycine oxidase ThiO |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_2796|M.avium_104 ------MARN-QQIVVIGAGVSGLTSAICLAEAGWPVRVWADTMPADTTS
MLBr_02011|M.leprae_Br4923 ------MASNGQQIVVIGAGVSGLTSAVCLAEAGWPVQLWAAAMPQQTTS
Mb1940c|M.bovis_AF2122/97 ------MAIGEQQVIVIGAGVSGLTSAICLAEAGWPVRVWAAALPQQTTS
Rv1905c|M.tuberculosis_H37Rv ------MAIGEQQVIVIGAGVSGLTSAICLAEAGWPVRVWAAALPQQTTS
MMAR_2801|M.marinum_M MGSGRTAASDAQQVVVIGAGVSGLTSALCLAEAGWPVRVWTDLLPRQTTS
MUL_2926|M.ulcerans_Agy99 MGSGRTAASDAQQVVVIGAGISGLTSALCLAEAGWPVRVWIDLLPRQTTS
Mflv_0197|M.gilvum_PYR-GCK -----MPAHTRGRLAVIGGGVIGLAVARRAALDGWATRVHRTEHPGA--S
Mvan_0708|M.vanbaalenii_PYR-1 -----MPAHTRGTLAVIGGGVIGLSVARRALQDGWAVRVHRAERAGA--S
MSMEG_0791|M.smegmatis_MC2_155 --------MTR-TVAVIGGGVIGLSVARRAALDGWTVRLHCTTERGA--S
MAB_4218c|M.abscessus_ATCC_199 -----MMSSQKGSVAVIGGGVIGLSVAREAARTGWRVVIHDDGAKGP--S
: ***.*: **: * ** . : *
MAV_2796|M.avium_104 AVAGAVWAPPRPAER-AAETLRWTEHSLRVFTELARD----PDSGVQLAP
MLBr_02011|M.leprae_Br4923 AVAGAVWAPPRPEER-ASTSLAWTGHSLQIFRELAND----PSTGVRMAP
Mb1940c|M.bovis_AF2122/97 AVAGAVWGP-RPKEP-VAKVRGWIEQSLHVFRDLAKD----PATGVRMTP
Rv1905c|M.tuberculosis_H37Rv AVAGAVWGP-RPKEP-VAKVRGWIEQSLHVFRDLAKD----PATGVRMTP
MMAR_2801|M.marinum_M AVAGAVWRP-RFVEP-VVKTRKWAEQSLHRFRELADD----PTSGVQLMP
MUL_2926|M.ulcerans_Agy99 AVAGAVWRP-RFVEP-VVKARKWAEQSLHRFRELADD----PTSGVQLMP
Mflv_0197|M.gilvum_PYR-GCK WVAGGMLAPHSEGWPGEEQLLTLGLESLRLWHEQFLGSLPAQVVTARESL
Mvan_0708|M.vanbaalenii_PYR-1 WVAGGMLAPHSEGWPGEERLLQIGLESLRLWREGFLDGLPPEVVTARESL
MSMEG_0791|M.smegmatis_MC2_155 WVAGGMLAPHSEGWPGEEQLLQLGLESLRLWHSGFLDGLPEKVVTARESL
MAB_4218c|M.abscessus_ATCC_199 WVAGGMLAPYSEAWPGEDELLELGIESLGIWRDGFIDDVENPVITARGSL
***.: * .** : . . .:
MAV_2796|M.avium_104 ALAVGELTASEAMSTAASLIPELRPADPADLPPGYRTGFHATVP-----M
MLBr_02011|M.leprae_Br4923 ALTVGDLPGANAMGLAAKLIPDLRPADLADLPDGFGAGFFGTMP-----M
Mb1940c|M.bovis_AF2122/97 ALSVGDRIETGAMPPGLELIPDVRPADPADVPGGFRAGFHATLP-----M
Rv1905c|M.tuberculosis_H37Rv ALSVGDRIETGAMPPGLELIPDVRPADPADVPGGFRAGFHATLP-----M
MMAR_2801|M.marinum_M AISVGEIAEVDVTASGEDMIPGLRPVADTDVPDGFPTATAATLP-----M
MUL_2926|M.ulcerans_Agy99 AISVGEIAEVDVTASGEDMIPGLRPVADTDVPDGFPAATAATLP-----M
Mflv_0197|M.gilvum_PYR-GCK VVAVDQADAADLRTVAAWLCAQGHPVTPTTSARDMEPLLAQGIRHGFSAD
Mvan_0708|M.vanbaalenii_PYR-1 VVAVDPADAADLKTVAAWLSGQGHPVTLTTSAREVEPLLAQGIRHGFRAE
MSMEG_0791|M.smegmatis_MC2_155 VVAVDRADAADLRTVAEWLAAQGHPVEFTTAARDVEPLLAQGIRHGFRAT
MAB_4218c|M.abscessus_ATCC_199 TVAVDTADVGELRTMTGWLAARGHPVTEIANARDVEPMLAQNVRRGFTAP
.::*. : :*. . . :
MAV_2796|M.avium_104 IDMPHYLGYLTRRLTAAGGEIEEHRVGSLDEVADH--ADIVVNCAGLRAG
MLBr_02011|M.leprae_Br4923 IDMPQYLDYLTARLAAAGCELETRSVRSLAEAADT--APIIVNCTGLGAA
Mb1940c|M.bovis_AF2122/97 IDMPQYLDCLTQRLAATGCEIETRPLRSLAEAAEA--APIVINCAGLGAR
Rv1905c|M.tuberculosis_H37Rv IDMPQYLDCLTQRLAATGCEIETRPLRSLAEAAEA--APIVINCAGLGAR
MMAR_2801|M.marinum_M IDMPRYLDYLTTRLAAAGCEIEIHPVRSLTEAAQS--APIVINCSGLGAR
MUL_2926|M.ulcerans_Agy99 IDMPRYLDYLTTRLAAAGCEIEIHPVRSLTEAAQS--APIVINCSGLGAR
Mflv_0197|M.gilvum_PYR-GCK TELAVDNRAVVAALAEQCERLDVRWAPPVDSLAETADADAVVIANGIDAP
Mvan_0708|M.vanbaalenii_PYR-1 TELAVDNRAVVAALAAECERLGVEWAPPVAALTDAGPADTVVIANGIDAP
MSMEG_0791|M.smegmatis_MC2_155 TELAVDNRGVVDALAAHCERLAVRWAGQVDDLADV-DADAVVIANGIDAP
MAB_4218c|M.abscessus_ATCC_199 EELSVDNRKVLQALTAECEALGVGRGPAAVHTRDV-DADQVVIANGVQAA
::. : *: : : * :: . *: *
MAV_2796|M.avium_104 ALTGDDTVRPLFGQHVVLTNPG----VRQLFMELNDGPEWTCYFPHPQRV
MLBr_02011|M.leprae_Br4923 ALANDDTVRPLFGQHVVLTNPG----LQQLFLEVNNGSEWICYFPHPLRV
Mb1940c|M.bovis_AF2122/97 ELAGDATVWPRFGQHVVLTNPG----LEQLFIERTGGSEWICYFAHPQRV
Rv1905c|M.tuberculosis_H37Rv ELAGDATVWPRFGQHVVLTNPG----LEQLFIERTGGSEWICYFAHPQRV
MMAR_2801|M.marinum_M ELAGDDTLRPRFGQHVVLANPG----LDQLFMQLGDGPEWICYFPHPHRV
MUL_2926|M.ulcerans_Agy99 ELAGDDTLRPRFGQHVVLANPG----LDQLFMQLGDGPEWICYFPHPHRV
Mflv_0197|M.gilvum_PYR-GCK ALWPGLPVRPVKGEVLRLRWRRGCLPVPRRVVRARVRGRQVYVVPRPDGV
Mvan_0708|M.vanbaalenii_PYR-1 TLWPGLPVRPVKGEVLRLRWRRGCLPVPQRVVRARVHGRQVYVVPRADGV
MSMEG_0791|M.smegmatis_MC2_155 RLWPDLPVRPVKGEVLRLRWRKGCMPVPQRVIRARVHGRQVYLVPRADGV
MAB_4218c|M.abscessus_ATCC_199 ALA-GLPVRPVKGEVLRLRQRPGAMPPPANVIRARVHGRHVYLVPRADGV
* . .: * *: : * .:. . ..:. *
MAV_2796|M.avium_104 VCGGISIAGRWDTTADPAVTERILQRCRRIEPRLGEAEVIEVITGLRPDR
MLBr_02011|M.leprae_Br4923 VCGGISIPGRWDTTPDPAVTDRILQRCRRIEPRLGEAAVIETITGLRPDR
Mb1940c|M.bovis_AF2122/97 VCGGISIPGRWDTTPEPEITERILQRCRRIQPRLAEAAVIETITGLRPDR
Rv1905c|M.tuberculosis_H37Rv VCGGISIPGRWDPTPEPEITERILQRCRRIQPRLAEAAVIETITGLRPDR
MMAR_2801|M.marinum_M VCGGISILDRWDTTADPQVTDRILRDCRRVEPRLADAPVIETITGLRPDR
MUL_2926|M.ulcerans_Agy99 VCGGISILDRWDTTADPQVTDRILRDCRRIEPRLADAPVIETITGLRPDR
Mflv_0197|M.gilvum_PYR-GCK VVGATQYEHGRDTAPTVGGVRDLLDDACAVMPGLGEYEFAEAAAGLRPMT
Mvan_0708|M.vanbaalenii_PYR-1 VVGATQYEHGRDTAPTVSGVRDLLDDACAVMPALGEYEFAEAAAGLRPMT
MSMEG_0791|M.smegmatis_MC2_155 VVGATQYEHGRDTAPVVSGVRDLLEDACAVMPALGEYELAEIAAGLRPMT
MAB_4218c|M.abscessus_ATCC_199 VVGATQYEHGHDTAPAVAGVRDLLDDACALLPCLGEYEFAECAAGLRPMT
* *. . *.:. . :* . : * *.: . * :****
MAV_2796|M.avium_104 PSVRLQAEPLRRARCIHNYGHSSNGVTLS-WGCARDVLALVDDAR-----
MLBr_02011|M.leprae_Br4923 PSPRVEVELSGSVRYIHNYGHSSSGVTLS-WGCARDVVRLVSD-------
Mb1940c|M.bovis_AF2122/97 PSVRVEAEPIGRALCIHNYGHGGDGVTLS-WGCAREVVNLVGGG------
Rv1905c|M.tuberculosis_H37Rv PSVRVEAEPIGRALCIHNYGHGGDGVTLS-WGCAREVVNLVGGG------
MMAR_2801|M.marinum_M PSVRVEVEQIGATRCIHNYGHGGDGVTLS-WGCALDVARLAGLDC-----
MUL_2926|M.ulcerans_Agy99 PSVRVEVEQIGTTRCIHNYGHGGDGVTLS-WGCALDVARLAGLDC-----
Mflv_0197|M.gilvum_PYR-GCK PDN-LPLVGRLDERTLVAAGHGRSGFLLAPWTVEKIAAELEGAMVMEVAE
Mvan_0708|M.vanbaalenii_PYR-1 PDN-LPLVGRLDERTLVAAGHGRSGFLLAPWTAESIAAELEGALVR----
MSMEG_0791|M.smegmatis_MC2_155 PDG-LPVVERVDERTVVAVGHGRNGFLLAPWTAERVAAELEVGVGAK---
MAB_4218c|M.abscessus_ATCC_199 DDN-LPMVGRIDERVVVAAGHGRSGFLLAPWTAKTIGAVLDGGESPAAVD
. : : **. .*. *: * *
MAV_2796|M.avium_104 -------------
MLBr_02011|M.leprae_Br4923 -------------
Mb1940c|M.bovis_AF2122/97 -------------
Rv1905c|M.tuberculosis_H37Rv -------------
MMAR_2801|M.marinum_M -------------
MUL_2926|M.ulcerans_Agy99 -------------
Mflv_0197|M.gilvum_PYR-GCK -------------
Mvan_0708|M.vanbaalenii_PYR-1 -------------
MSMEG_0791|M.smegmatis_MC2_155 -------------
MAB_4218c|M.abscessus_ATCC_199 PRRFEKAHSQEAR