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M. marinum M MMAR_2409 (chaA)

annotation: ionic transporter integral membrane protein ChaA
coordinates: 2908067 - 2909149
length: 360

MWKRLSWTVVAPLLALVALVLSWGQHIGPVVGLLEAVLLAGAVLAAVHHAEVVAHRVGEPFGSLVLAVAV
TVIEVALIVTLMASGGHQAATLARDTVFAAVMITTNGIAGLSLLLGSQRYGVTLFNAHGSGTALATVTTL
ATLSLVLPTFTTSQPGPEFSPGQLGFAAVASLALYLLFVFTQTVRHRDFFLPVAQKGAVDDDRHADPPST
RAAMTSLALLLVALVAVVGLAKMESPIIERMVVAAGFPQSFVGVIIATLVLLPETLAAGRAARQGRLQIS
LNLAYGSAMASIGLTIPTIALASIWLSGPLLLGLGALQLVLLVLTVVVSALTVLPGRATRLQGELHLVVL
AAYIFLAVSP
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_2409chaA-100% (360)ionic transporter integral membrane protein ChaA

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1633chaA1e-16786.11% (360) ionic transporter integral membrane protein chaA
M. gilvum PYR-GCKMflv_1475-1e-0624.55% (330) major facilitator transporter
M. tuberculosis H37RvRv1607chaA1e-16786.11% (360) ionic transporter integral membrane protein chaA
M. leprae Br4923MLBr_01267-1e-15678.30% (364) putative antiporter
M. abscessus ATCC 19977-----
M. avium 104MAV_3179chaA1e-15679.67% (359) calcium/proton exchanger
M. smegmatis MC2 155-----
M. thermoresistible (build 8)TH_2104-4e-0724.34% (378) sulfate permease
M. ulcerans Agy99-----
M. vanbaalenii PYR-1-----

CLUSTAL 2.0.9 multiple sequence alignment


Mb1633|M.bovis_AF2122/97            ---MLKR--VPWTVVLPSLAFVALVLTWGKQIGP--------VVGLLAAV
Rv1607|M.tuberculosis_H37Rv         ---MLKR--VPWTVVLPSLAFVALVLTWGKQIGP--------VVGLLAAV
MMAR_2409|M.marinum_M               ---MWKR--LSWTVVAPLLALVALVLSWGQHIGP--------VVGLLEAV
MLBr_01267|M.leprae_Br4923          ---MLKR--IAWTALVPLFALAVLALTWGREIGP--------VVTALQAA
MAV_3179|M.avium_104                MSKWLSRNVLSWTVVVPVLAVVVLALIWGERLGP--------VLVALAAL
TH_2104|M.thermoresistible__bu      --VIATAKENLIRLLPSRRDYAELPRSWRRDILAGITVGVVALPLALAFG
Mflv_1475|M.gilvum_PYR-GCK          -MAPLSPTAQRAPLLAAGFTTAFGAHAVAGTLGT-------TTTGTAASL
                                         .        : .    .         : .                

Mb1633|M.bovis_AF2122/97            LLAGAVLAAVNHAEVVAARVGEPFGSLVLAVAVTTIEVALIVALMVSGGD
Rv1607|M.tuberculosis_H37Rv         LLAGAVLAAVNHAEVVAARVGEPFGSLVLAVAVTTIEVALIVALMVSGGD
MMAR_2409|M.marinum_M               LLAGAVLAAVHHAEVVAHRVGEPFGSLVLAVAVTVIEVALIVTLMASGGH
MLBr_01267|M.leprae_Br4923          LLTGAVLAAVHHAEVVAHRVGEPFGSLVLAAAVTVIEVALIVTLMASGEN
MAV_3179|M.avium_104                FLIGAVVAAVHHAEVVAHRIGEPFGSLVLAAAVTIIEVALIVELMASGGN
TH_2104|M.thermoresistible__bu      ISSGVGAAAGLITAVVAGLVAAVFGGSHIQVSGPTGAMAVILAPIVAQHG
Mflv_1475|M.gilvum_PYR-GCK          LTLGAMLAIYDGAEVILK---PLFGTLADRIGARTVLIAGLAVFAVASLS
                                    :  *.  *    : *:       **      .     :* :    .:   

Mb1633|M.bovis_AF2122/97            DAATLARDTVFAAVMITTNGIAGLS---------LLLGSLRYGVTLFNPH
Rv1607|M.tuberculosis_H37Rv         DAATLARDTVFAAVMITTNGIAGLS---------LLLGSLRYGVTLFNPH
MMAR_2409|M.marinum_M               QAATLARDTVFAAVMITTNGIAGLS---------LLLGSQRYGVTLFNAH
MLBr_01267|M.leprae_Br4923          ESWTLARDTAFAALMITTNGIAGFS---------LLLGSRRYGVTLFNAH
MAV_3179|M.avium_104                ETATLARDTAFAALMITTNGIAGLS---------LLLGSRRYGVTLFNAE
TH_2104|M.thermoresistible__bu      -LTSIALVTVLAGLIVLAAGITGLGRAVTFIPWPVIEGFTLGIAAIIFLQ
Mflv_1475|M.gilvum_PYR-GCK          FAVADETAWLWAARLGQGIGAAAFS-----------PAASALVARLAPAS
                                       :       *. :    * :.:.            .     . :    

Mb1633|M.bovis_AF2122/97            GSGAALATVTTLATLSLVLPTFTTSQSGPELSPGQLIFAGAASLGLYVLF
Rv1607|M.tuberculosis_H37Rv         GSGAALATVTTLATLSLVLPTFTTSQSGPELSPGQLIFAGAASLGLYVLF
MMAR_2409|M.marinum_M               GSGTALATVTTLATLSLVLPTFTTSQPGPEFSPGQLGFAAVASLALYLLF
MLBr_01267|M.leprae_Br4923          GSGAALATLTTLATLSLVLPTFTTSHRGNEFSPGQLAFAAVASLGLYLLF
MAV_3179|M.avium_104                GSGAALATLTTLATLSLVLPAFTTTQVGKEFSPGQLTFAAVASLLVYLLF
TH_2104|M.thermoresistible__bu      QVPAAFATEAPAGQRTLVAAWHVVTHADWTAAVKTLSVVSLVALLMVVLP
Mflv_1475|M.gilvum_PYR-GCK          GQGRAFGTYGSYKSVGYTLGPLIGG-AIVTFGGLQALFAVMAALAAAVAV
                                        *:.*  .      .             .     ..  .:*   :  

Mb1633|M.bovis_AF2122/97            LFTQTVRH-------RDFFLPVAQKG----AVEDDSHADPPSTRAALLSL
Rv1607|M.tuberculosis_H37Rv         LFTQTVRH-------RDFFLPVAQKG----AVEDDSHADPPSTRAALLSL
MMAR_2409|M.marinum_M               VFTQTVRH-------RDFFLPVAQKG----AVDDDRHADPPSTRAAMTSL
MLBr_01267|M.leprae_Br4923          VFTQTIRH-------RDFFLPVAQKGQKGLFEEDESHADPPSARSALISL
MAV_3179|M.avium_104                VFTQTVRH-------RDFFLPIAQKGQKSLFE-DESHADPPSTREALVSL
TH_2104|M.thermoresistible__bu      RLHRSIPESLTAVVAATVIVTVFGISVATIGELPSQLPTPVLPQADMGAM
Mflv_1475|M.gilvum_PYR-GCK          WAAVAVPR-----------LAVLPRT--------RQTLLDTVRRFSESSF
                                        :: .           :.:                     :    ::

Mb1633|M.bovis_AF2122/97            GLLLVALVAVVGLAKVESPVIEEVVSAAGFP-----------QSFVGVVI
Rv1607|M.tuberculosis_H37Rv         GLLLVALVAVVGLAKVESPVIEEVVSAAGFP-----------QSFVGVVI
MMAR_2409|M.marinum_M               ALLLVALVAVVGLAKMESPIIERMVVAAGFP-----------QSFVGVII
MLBr_01267|M.leprae_Br4923          ALLLVALIAVVGLAELQSSAIEHLVTAVGFP-----------QPFVGVVI
MAV_3179|M.avium_104                VLLLCALVAVVGLAEEESPAVERAVTAVGFP-----------QTFVGVII
TH_2104|M.thermoresistible__bu      QTLLGAALAIAALAAIESLLSARVAATMSATGPYHPDRELVGQGMASVAS
Mflv_1475|M.gilvum_PYR-GCK          VTPTLALAAATAALSAGVGFLPVLGTDFGLS-----------PVVTGAVV
                                         *  * ..                . .             ....  

Mb1633|M.bovis_AF2122/97            ATLVLLPETLA--AARAARQGR---------------LQTSLNLAYG---
Rv1607|M.tuberculosis_H37Rv         ATLVLLPETLA--AARAARQGR---------------LQTSLNLAYG---
MMAR_2409|M.marinum_M               ATLVLLPETLA--AGRAARQGR---------------LQISLNLAYG---
MLBr_01267|M.leprae_Br4923          ATLVLLPETLA--AVRAARRGR---------------IQTSLNLAYG---
MAV_3179|M.avium_104                AALVLLPETLA--AVRAARQGR---------------IQISLNLAYG---
TH_2104|M.thermoresistible__bu      GLFGGMPATGA--IARTAVNVRSGARTRLAAIVHSLVLLAVVYLATGPVS
Mflv_1475|M.gilvum_PYR-GCK          SVLALTTAVVQPLAGRAADSGR---------------ISLTSGLFTG---
                                    . :   . .      *:*   *               :     *  *   

Mb1633|M.bovis_AF2122/97            ----------------------------SAMASIGLTIPTIALASLWLSG
Rv1607|M.tuberculosis_H37Rv         ----------------------------SAMASIGLTIPTIALASLWLSG
MMAR_2409|M.marinum_M               ----------------------------SAMASIGLTIPTIALASIWLSG
MLBr_01267|M.leprae_Br4923          ----------------------------SAMASIGLTIPAIALASIWLTG
MAV_3179|M.avium_104                ----------------------------SAMASIGLTIPAIALASIWLKG
TH_2104|M.thermoresistible__bu      AIPLSALAGVLMVTSFRMVSLHTARRILRSTRSDALTFVLTALVTITFDL
Mflv_1475|M.gilvum_PYR-GCK          ----------------------------VVVTAAGVAAAALPGLVGLLGG
                                                                    : .::    .     :  

Mb1633|M.bovis_AF2122/97            PLQLGLGAIQLVLLVLTVVVS----VLTVVPGRATRLQGEVHLVLLAAYL
Rv1607|M.tuberculosis_H37Rv         PLQLGLGAIQLVLLVLTVVVS----VLTVVPGRATRLQGEVHLVLLAAYL
MMAR_2409|M.marinum_M               PLLLGLGALQLVLLVLTVVVS----ALTVLPGRATRLQGELHLVVLAAYI
MLBr_01267|M.leprae_Br4923          PLILGLGATQLVLLALTVVIS----VLTVVPGRATRLQGEVHLVLLAAFV
MAV_3179|M.avium_104                PLVLGLGAIQLVLLALTVVIS----VLTVVPGRATRLQGEVHLVLLAAYV
TH_2104|M.thermoresistible__bu      IEAVQIGVLVAAFFALRNVARRSGVTREELPGEPQPGDERIALLRLEGSM
Mflv_1475|M.gilvum_PYR-GCK          AVVIGVGCGLITPLAFTMLAR----STPEERLGQTMGAAEIGRECGDAAG
                                       : :*    . :.:  :                    .:      .  

Mb1633|M.bovis_AF2122/97            FLAVVP--------------------------------------------
Rv1607|M.tuberculosis_H37Rv         FLAVVP--------------------------------------------
MMAR_2409|M.marinum_M               FLAVSP--------------------------------------------
MLBr_01267|M.leprae_Br4923          FLAIIP--------------------------------------------
MAV_3179|M.avium_104                FLAVSP--------------------------------------------
TH_2104|M.thermoresistible__bu      FFGVAERMSSTISEIEADDISVVIIRLSQLGTLDATGANSLAQIATELER
Mflv_1475|M.gilvum_PYR-GCK          PLVVAAIAAASTVPFGFLGLAAVVAASGVGVRRGRGRVGGVG--------
                                     : :                                              

Mb1633|M.bovis_AF2122/97            --------------------------------------------------
Rv1607|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2409|M.marinum_M               --------------------------------------------------
MLBr_01267|M.leprae_Br4923          --------------------------------------------------
MAV_3179|M.avium_104                --------------------------------------------------
TH_2104|M.thermoresistible__bu      RGITVIIKGVQPEHSKLLSNVGVFESLRHEKHLIDSLEDAIEHARSHVAR
Mflv_1475|M.gilvum_PYR-GCK          --------------------------------------------------
                                                                                      

Mb1633|M.bovis_AF2122/97            --------
Rv1607|M.tuberculosis_H37Rv         --------
MMAR_2409|M.marinum_M               --------
MLBr_01267|M.leprae_Br4923          --------
MAV_3179|M.avium_104                --------
TH_2104|M.thermoresistible__bu      QQTARTTS
Mflv_1475|M.gilvum_PYR-GCK          --------