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SKWLSRNVLSWTVVVPVLAVVVLALIWGERLGPVLVALAALFLIGAVVAAVHHAEVVAHRIGEPFGSLVL AAAVTIIEVALIVELMASGGNETATLARDTAFAALMITTNGIAGLSLLLGSRRYGVTLFNAEGSGAALAT LTTLATLSLVLPAFTTTQVGKEFSPGQLTFAAVASLLVYLLFVFTQTVRHRDFFLPIAQKGQKSLFEDES HADPPSTREALVSLVLLLCALVAVVGLAEEESPAVERAVTAVGFPQTFVGVIIAALVLLPETLAAVRAAR QGRIQISLNLAYGSAMASIGLTIPAIALASIWLKGPLVLGLGAIQLVLLALTVVISVLTVVPGRATRLQG EVHLVLLAAYVFLAVSP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_3179 | chaA | - | 100% (368) | calcium/proton exchanger |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1633 | chaA | 1e-150 | 78.43% (357) | ionic transporter integral membrane protein chaA |
| M. gilvum PYR-GCK | Mflv_1475 | - | 2e-05 | 23.41% (299) | major facilitator transporter |
| M. tuberculosis H37Rv | Rv1607 | chaA | 1e-150 | 78.43% (357) | ionic transporter integral membrane protein chaA |
| M. leprae Br4923 | MLBr_01267 | - | 1e-162 | 82.78% (360) | putative antiporter |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_2409 | chaA | 1e-156 | 79.67% (359) | ionic transporter integral membrane protein ChaA |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1633|M.bovis_AF2122/97 ---MLKR--VPWTVVLPSLAFVALVLTWGKQIGPVVGLLAAVLLAGAVLA
Rv1607|M.tuberculosis_H37Rv ---MLKR--VPWTVVLPSLAFVALVLTWGKQIGPVVGLLAAVLLAGAVLA
MMAR_2409|M.marinum_M ---MWKR--LSWTVVAPLLALVALVLSWGQHIGPVVGLLEAVLLAGAVLA
MAV_3179|M.avium_104 MSKWLSRNVLSWTVVVPVLAVVVLALIWGERLGPVLVALAALFLIGAVVA
MLBr_01267|M.leprae_Br4923 ---MLKR--IAWTALVPLFALAVLALTWGREIGPVVTALQAALLTGAVLA
Mflv_1475|M.gilvum_PYR-GCK -MAPLSPTAQRAPLLAAGFTTAFGAHAVAGTLGTTTTGTAASLLTLGAML
. . : . :: . . . :*.. * :* ..:
Mb1633|M.bovis_AF2122/97 AVNHAEVVAARVGEPFGSLVLAVAVTTIEVALIVALMVSGGDDAATLARD
Rv1607|M.tuberculosis_H37Rv AVNHAEVVAARVGEPFGSLVLAVAVTTIEVALIVALMVSGGDDAATLARD
MMAR_2409|M.marinum_M AVHHAEVVAHRVGEPFGSLVLAVAVTVIEVALIVTLMASGGHQAATLARD
MAV_3179|M.avium_104 AVHHAEVVAHRIGEPFGSLVLAAAVTIIEVALIVELMASGGNETATLARD
MLBr_01267|M.leprae_Br4923 AVHHAEVVAHRVGEPFGSLVLAAAVTVIEVALIVTLMASGENESWTLARD
Mflv_1475|M.gilvum_PYR-GCK AIYDGAEVILKP--LFGTLADRIGARTVLIAGLAVFAVAS--LSFAVADE
*: .. * : **:*. .. : :* :. : .:. : ::* :
Mb1633|M.bovis_AF2122/97 TVFAAVMITTNGIAGLSLLLGSLRYGVTLFNPHGSGAALATVTTLATLSL
Rv1607|M.tuberculosis_H37Rv TVFAAVMITTNGIAGLSLLLGSLRYGVTLFNPHGSGAALATVTTLATLSL
MMAR_2409|M.marinum_M TVFAAVMITTNGIAGLSLLLGSQRYGVTLFNAHGSGTALATVTTLATLSL
MAV_3179|M.avium_104 TAFAALMITTNGIAGLSLLLGSRRYGVTLFNAEGSGAALATLTTLATLSL
MLBr_01267|M.leprae_Br4923 TAFAALMITTNGIAGFSLLLGSRRYGVTLFNAHGSGAALATLTTLATLSL
Mflv_1475|M.gilvum_PYR-GCK TAWLWAARLGQGIGAAAFSPAASALVARLAPASGQGRAFGTYGSYKSVGY
*.: :**.. :: .: . * . *.* *:.* : ::.
Mb1633|M.bovis_AF2122/97 VLPTFTTSQSGPELSPGQLIFAGAASLGLYVLFLFTQTVRHRDFFLPVAQ
Rv1607|M.tuberculosis_H37Rv VLPTFTTSQSGPELSPGQLIFAGAASLGLYVLFLFTQTVRHRDFFLPVAQ
MMAR_2409|M.marinum_M VLPTFTTSQPGPEFSPGQLGFAAVASLALYLLFVFTQTVRHRDFFLPVAQ
MAV_3179|M.avium_104 VLPAFTTTQVGKEFSPGQLTFAAVASLLVYLLFVFTQTVRHRDFFLPIAQ
MLBr_01267|M.leprae_Br4923 VLPTFTTSHRGNEFSPGQLAFAAVASLGLYLLFVFTQTIRHRDFFLPVAQ
Mflv_1475|M.gilvum_PYR-GCK TLGPLIGG-AIVTFGGLQALFAVMAALAA-AVAVWAAVAVPRLAVLPRTR
.* .: :. * ** *:* : ::: . * .** ::
Mb1633|M.bovis_AF2122/97 KG----AVEDDSHADPPSTRAALLSLGLLLVALVAVVGLAKVESPVIEEV
Rv1607|M.tuberculosis_H37Rv KG----AVEDDSHADPPSTRAALLSLGLLLVALVAVVGLAKVESPVIEEV
MMAR_2409|M.marinum_M KG----AVDDDRHADPPSTRAAMTSLALLLVALVAVVGLAKMESPIIERM
MAV_3179|M.avium_104 KGQKSLFE-DESHADPPSTREALVSLVLLLCALVAVVGLAEEESPAVERA
MLBr_01267|M.leprae_Br4923 KGQKGLFEEDESHADPPSARSALISLALLLVALIAVVGLAELQSSAIEHL
Mflv_1475|M.gilvum_PYR-GCK QT----LLDTVRRFSESSFVTPTLALAAATAALSAGVGFLPVLG------
: : . .* . :* ** * **: .
Mb1633|M.bovis_AF2122/97 VSAAGFPQSFVGVVIATLVLLPETLA--AARAARQGRLQTSLNLAYGSAM
Rv1607|M.tuberculosis_H37Rv VSAAGFPQSFVGVVIATLVLLPETLA--AARAARQGRLQTSLNLAYGSAM
MMAR_2409|M.marinum_M VVAAGFPQSFVGVIIATLVLLPETLA--AGRAARQGRLQISLNLAYGSAM
MAV_3179|M.avium_104 VTAVGFPQTFVGVIIAALVLLPETLA--AVRAARQGRIQISLNLAYGSAM
MLBr_01267|M.leprae_Br4923 VTAVGFPQPFVGVVIATLVLLPETLA--AVRAARRGRIQTSLNLAYGSAM
Mflv_1475|M.gilvum_PYR-GCK -TDFGLSPVVTGAVVSVLALTTAVVQPLAGRAADSGRISLTSGLFTGVVV
*:. ..*.:::.*.* . .: * *** **:. : .* * .:
Mb1633|M.bovis_AF2122/97 ASIGLTIPTIALASLWLSGPLQLGLGAIQLVLLVLTVVVS----------
Rv1607|M.tuberculosis_H37Rv ASIGLTIPTIALASLWLSGPLQLGLGAIQLVLLVLTVVVS----------
MMAR_2409|M.marinum_M ASIGLTIPTIALASIWLSGPLLLGLGALQLVLLVLTVVVS----------
MAV_3179|M.avium_104 ASIGLTIPAIALASIWLKGPLVLGLGAIQLVLLALTVVIS----------
MLBr_01267|M.leprae_Br4923 ASIGLTIPAIALASIWLTGPLILGLGATQLVLLALTVVIS----------
Mflv_1475|M.gilvum_PYR-GCK TAAGVAAAALPGLVGLLGGAVVIGVGCGLITPLAFTMLARSTPEERLGQT
:: *:: .::. * *.: :*:*. :. *.:*::
Mb1633|M.bovis_AF2122/97 -----------------VLTVVPGRATRLQGEVHLVLLAAYLFLAVVP--
Rv1607|M.tuberculosis_H37Rv -----------------VLTVVPGRATRLQGEVHLVLLAAYLFLAVVP--
MMAR_2409|M.marinum_M -----------------ALTVLPGRATRLQGELHLVVLAAYIFLAVSP--
MAV_3179|M.avium_104 -----------------VLTVVPGRATRLQGEVHLVLLAAYVFLAVSP--
MLBr_01267|M.leprae_Br4923 -----------------VLTVVPGRATRLQGEVHLVLLAAFVFLAIIP--
Mflv_1475|M.gilvum_PYR-GCK MGAAEIGRECGDAAGPLVVAAIAAASTVPFGFLGLAAVVAASGVGVRRGR
.::.:.. :* * : *. :.* :.:
Mb1633|M.bovis_AF2122/97 -------
Rv1607|M.tuberculosis_H37Rv -------
MMAR_2409|M.marinum_M -------
MAV_3179|M.avium_104 -------
MLBr_01267|M.leprae_Br4923 -------
Mflv_1475|M.gilvum_PYR-GCK GRVGGVG