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M. marinum M MMAR_1290 (-)

annotation: cationic amino acid transport integral membrane protein
coordinates: 1573901 - 1575385
length: 494

MAGRLRTKSVEQSIADTDEPETRLRKDLTWRDLVVFGVSVVIGAGIFTVTASTAGDITGPAIWISFLIAA
GTCALAALCYAEFASTLPVAGSAYTFSYATFGEFLAWVIGWNLVLELAIGAAVVAKGWSSYLGTVFGFSG
GTADFGSIRLDWGALLIVSIVSLLVAYGTKLSSRFSAVVTTIKVAVVILVVVVGAFYVKAANYSPFIPEP
EAGPEGRGADQSLLSLLTGAPGSHYGWYGVLAGASIVFFAFIGFDIVATMAEETKHPQRDVPRGILVSLG
VVTLLYVAVSIVLSGMVSYTQLRTVSGGGHANLATAFKANGVYWASGIISVGALAGLTTVVMVLMLGQCR
VLFAMARDGLLPRQLAKTGARGTPVRITVLVAVVVGATASVFPITKLEEMVNVGTLFAFVLVSAGVIVLR
KKRPDLERGFRAPWVPVLPIASLCACLWLMLNLTALTWIRFGVWLLVGTVIYVGYGRKHSMVGRRQLAEA
AMDK
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_1290--100% (494)cationic amino acid transport integral membrane protein
M. marinum MMMAR_3621rocE7e-7936.69% (477) cationic amino acid transport integral membrane protein RocE
M. marinum MMMAR_2407rocE_13e-7634.11% (472) cationic amino acid transport integral membrane protein,

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3281c-0.086.15% (491) cationic amino acid transport integral membrane protein
M. gilvum PYR-GCKMflv_4722-0.074.13% (491) amino acid permease-associated region
M. tuberculosis H37RvRv3253c-0.086.15% (491) cationic amino acid transport integral membrane protein
M. leprae Br4923MLBr_01305ansP28e-1922.44% (468) putative L-asparagine permease
M. abscessus ATCC 19977MAB_3599c-0.068.25% (485) putative amino acid permease
M. avium 104MAV_4216-0.084.25% (489) cationic amino acid transporter
M. smegmatis MC2 155MSMEG_1838-0.072.93% (495) cationic amino acid transporter
M. thermoresistible (build 8)TH_0471-0.072.99% (485) POSSIBLE CATIONIC AMINO ACID TRANSPORT INTEGRAL MEMBRANE
M. ulcerans Agy99MUL_2597-0.099.60% (494) cationic amino acid transport integral membrane protein
M. vanbaalenii PYR-1Mvan_1740-0.073.35% (484) amino acid permease-associated region

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_1290|M.marinum_M               MAG--------RLRTKSVEQSIADTDEPETRLRKDLTWRDLVVFGVSVVI
MUL_2597|M.ulcerans_Agy99           MAG--------GLRTKSVEQSIADTDEPETRLRKDLTWRDLVVFGVSVVI
Mb3281c|M.bovis_AF2122/97           MAG--------RRRMKSVEQSIADTDEPTTRLRKDLTWWDLVVFGVSVVI
Rv3253c|M.tuberculosis_H37Rv        MAG--------RRRMKSVEQSIADTDEPTTRLRKDLTWWDLVVFGVSVVI
MAV_4216|M.avium_104                MAS--------RWRTKSVEQSIADTDEPDTRLRKDLTWWDLVVFGVAVVI
Mflv_4722|M.gilvum_PYR-GCK          MTQEPVTQAPGRLRLKSVEQSIADTDEPGTKLRKDLNWWDLTVFGVSVVI
Mvan_1740|M.vanbaalenii_PYR-1       MVQEPGAQTVGRRRTKSVEQSIADTDEPSTRLRKELNWWDLTVFGVSVVI
MSMEG_1838|M.smegmatis_MC2_155      MTT--------RWRTKSVEQSIADTDEPSTRLRKDLTWWDLTVFGVSVVI
TH_0471|M.thermoresistible__bu      MTD--------RLRVKSVEQSIADTDEPDSRLRKDLSWWDLTVFGVSVVI
MAB_3599c|M.abscessus_ATCC_199      MPGS------GLWRTKSVEQSIADTDEPETKLRRDLTWWDLTVFGVSVVI
MLBr_01305|M.leprae_Br4923          MAT------LAESPEPKSGASRAGVLGEEAGYHKGLKPRQLQMIGIGGAI
                                    *               .   * *..    :  :: *.  :* ::*:. .*

MMAR_1290|M.marinum_M               GAGIFTVTASTAGDITGPAIWISFLIAAGTCALAALCYAEFASTLPVAGS
MUL_2597|M.ulcerans_Agy99           GAGIFTVTASTAGDITGPAIWISFLIAAGTCALAALCYAEFASTLPVAGS
Mb3281c|M.bovis_AF2122/97           GAGIFTVTASTAGDITGPAIWISFLIAAATCALAALCYAEFASTLPVAGS
Rv3253c|M.tuberculosis_H37Rv        GAGIFTVTASTAGDITGPAIWISFLIAAATCALAALCYAEFASTLPVAGS
MAV_4216|M.avium_104                GAGIFTVTASTTGDITGPAIWVSFVIAAGTCALAALCYAEFASTLPVAGS
Mflv_4722|M.gilvum_PYR-GCK          GAGIFTITASTAANITGPAISLSFIFAAIACGLAALCYAEFASTVPVAGS
Mvan_1740|M.vanbaalenii_PYR-1       GAGIFTITASTAANITGPAISLSFIIAAIACGLAALCYAEFASTVPVAGS
MSMEG_1838|M.smegmatis_MC2_155      GAGIFTITASTAGNLTGPAISISFLIAAVACGLAALCYAEFASTVPVAGS
TH_0471|M.thermoresistible__bu      GAGIFTVTASTAGNITGPAISVSFIIAAIACGLAALCYAEFASTVPVAGS
MAB_3599c|M.abscessus_ATCC_199      GAGIFTVTASTAANVTGPAISLSFIMAAIGCGLAAMCYAEFASTIPVAGS
MLBr_01305|M.leprae_Br4923          GTGLFLGAGGRLAKAG-PGLFLVYAVCGVFVFLILRALGELVLHRPSSGS
                                    *:*:*  :..  ..   *.: : : ...    *   . .*:.   * :**

MMAR_1290|M.marinum_M               AYTFSYATFGEFLAWVIGWNLVLELAIGAAVVAKGWSSYLGTVFGFSGGT
MUL_2597|M.ulcerans_Agy99           AYTFSYATFGEFLAWVIGWNLVLELAIGAAVVAKGWSSYLGTVFGFSGGT
Mb3281c|M.bovis_AF2122/97           AYTFSYATFGEFLAWVIGWNLVLELAMGAAVVAKGWSSYLGTVFGFGNGT
Rv3253c|M.tuberculosis_H37Rv        AYTFSYATFGEFLAWVIGWNLVLELAMGAAVVAKGWSSYLGTVFGFGNGT
MAV_4216|M.avium_104                AYTFSYATFGEFLAWIIGWNLLLELAIGAAVVAKGWSSYLGTVFGFSGGT
Mflv_4722|M.gilvum_PYR-GCK          AYTFSYATFGEFVAWIIGWDLILEFAVAAAVVAKGWSSYLGTVFGFAGGT
Mvan_1740|M.vanbaalenii_PYR-1       AYTFSYATFGEFVAWIIGWDLILEFAVAAAVVAKGWSSYLGTVFGFAGGT
MSMEG_1838|M.smegmatis_MC2_155      AYTFSYATFGEFVAWIIGWDLILEFAVAAAVVAKGWSSYLGTVFNFGGGT
TH_0471|M.thermoresistible__bu      AYTFSYATFGEFVAWIIGWDLILEFSVAAAVVAKGWSSYLGEVFEFAGAT
MAB_3599c|M.abscessus_ATCC_199      AYTFSYATFGEFAAWILGWDLILEFSVGAATVAKGWSSYLSTVFGLSSGA
MLBr_01305|M.leprae_Br4923          FVSYAREFFGEKAAYVVGWLYFLDWAMTAIVDTTAIATYLHRWTIFTALP
                                      :::   ***  *:::**  .*: :: * . :.. ::**     :   .

MMAR_1290|M.marinum_M               ADFGS-IRLDWGALLIVSIVSLLVAYGTKLSSRFSAVVTTIKVAVVILVV
MUL_2597|M.ulcerans_Agy99           ADFGS-IRLDWGALLSVSIVSLLVAYGTKLSSRFSAVVTTIKVAVVILVV
Mb3281c|M.bovis_AF2122/97           GHLGS-LQLDWGALVIVTLVATLIALGTKLSSRFSAVVTAIKVSVVVLVV
Rv3253c|M.tuberculosis_H37Rv        GHLGS-LQLDWGALVIVTLVATLIALGTKLSSRFSAVVTAIKVSVVVLVV
MAV_4216|M.avium_104                VKFGA-AQLDWGALVIVGGVATLIALGTKLSSRFSAVITGIKVSVVVFVV
Mflv_4722|M.gilvum_PYR-GCK          AEVAG-FDLDWGALVIIAIVTAILAMGTKLSASVSLAITALKVSVVLLVV
Mvan_1740|M.vanbaalenii_PYR-1       TEVAG-FQLDWGALVIIALVTLILVMGTKLSAGVSLAITAVKVSVVLLVV
MSMEG_1838|M.smegmatis_MC2_155      MQIGGGLTLDWGALLIIAVVTFLLARGTKISAMVSLVITVIKVSVVLLVV
TH_0471|M.thermoresistible__bu      TRLGP-ITLDWGALLIIGFVTVLLATGTKLSANVSLAITVIKVGVVLLVV
MAB_3599c|M.abscessus_ATCC_199      VHLGA-VKIDWGALLIVSVLTVLLAVGTKLSSRVSLVITTIKVLVVLLVI
MLBr_01305|M.leprae_Br4923          QWTLA--------LLALAVVLVMNLISVEWFGELEFWAALIKVCALMAFL
                                                 *: :  :  :   ..:  . ..   : :** .:: .:

MMAR_1290|M.marinum_M               VVGAFYVKAANYSPFIPEPEAGPE---GRGADQSLLSLLTGAPGSHYGWY
MUL_2597|M.ulcerans_Agy99           VVGAFYVKAANYSPFIPEPEAGPE---GRGADQSLLSLLTGAPGSHYGWY
Mb3281c|M.bovis_AF2122/97           VVGAFYIRAANYSPFIPEPEVQHH---GGGLDQSVFSLLTGAQGSHYGWY
Rv3253c|M.tuberculosis_H37Rv        VVGAFYIRAANYSPFIPEPEVQHH---GGGLDQSVFSLLTGAQGSHYGWY
MAV_4216|M.avium_104                VVGVFYIKRANYSPFIPKPEAGGQ---AKGIDQSVLSLLTGAHTSHYGWY
Mflv_4722|M.gilvum_PYR-GCK          IVGAFYIKMENFSPFIPAPEPGEA--GGTGAEQSLFSLMTGAEGSHYGWY
Mvan_1740|M.vanbaalenii_PYR-1       IVGAFYIKAENFSPFVPAPEEGGS--GGTGTEQSLFSLLTGAEGSHYGWY
MSMEG_1838|M.smegmatis_MC2_155      FVGAFYINTANYTPFIPPAESGDGSGGGTGAEQSLFSLLTGAEGSHYGWY
TH_0471|M.thermoresistible__bu      IVGAFFIKAANYTPFIPPAEAGGE--AGRSLDQSLFSLITGAEGSSYGWY
MAB_3599c|M.abscessus_ATCC_199      IVGAFFIKTANYTPFIPPAEAGSS--SRQGLDQSLFSFVAGGSGSQYGWF
MLBr_01305|M.leprae_Br4923          VVGTIFLGGR-------YPVDGHN------TGLSLWTSHGGLFPT--GVA
                                    .**.:::           .              *: :   *   :  *  

MMAR_1290|M.marinum_M               GVLAGASIVFFAFIGFDIVATMAEETKHPQRDVPRGILVSLGVVTLLYVA
MUL_2597|M.ulcerans_Agy99           GVLAGASIVFFAFIGFDIVATMAEETKHPQRDVPRGILVSLGVVTLLYVA
Mb3281c|M.bovis_AF2122/97           GVLAGASIVFFAFIGFDIVATMAEETKRPQRDVPRGILASLGVVTLLYVA
Rv3253c|M.tuberculosis_H37Rv        GVLAGASIVFFAFIGFDIVATMAEETKRPQRDVPRGILASLGVVTLLYVA
MAV_4216|M.avium_104                GVLAGASIVFFAFIGFDIVATMAEETKHPQRDVPRGILASLGIVTLLYVA
Mflv_4722|M.gilvum_PYR-GCK          GLLAGASIVFFAFIGFDIVATTAEETKVPQRDVPRGILASLGIVTVLYVA
Mvan_1740|M.vanbaalenii_PYR-1       GVLAGASIVFFAFIGFDIVATTAEETRNPQRDVPRGILASLAIVTVLYVA
MSMEG_1838|M.smegmatis_MC2_155      GLLAGASIVFFAFIGFDIVATTAEETRNPQRDVPRGILGSLAIVTVLYVA
TH_0471|M.thermoresistible__bu      GLLAGASIVFFAFIGFDIIATTAEETKNPQRDVARGIMATLGIVTVLYVA
MAB_3599c|M.abscessus_ATCC_199      GVLAGASIVFFAFIGFDVVATTAEETRNPQKDVPRGIIASLVIVTVLYVA
MLBr_01305|M.leprae_Br4923          PLIVVSSGVMFAYAAVELVGTAAGETVEPKKIMPRAINSVIARIAIFYVG
                                     ::. :* *:**: ..:::.* * **  *:: :.*.*   :  ::::**.

MMAR_1290|M.marinum_M               VSIVLSGMVSYTQLRTVSGGGHANLATAFKANGVYWASGIISVGALAGLT
MUL_2597|M.ulcerans_Agy99           VSIVLSGMVSYTQLRTVSGGGHANLATAFKANGVYWASGIISVGALAGLT
Mb3281c|M.bovis_AF2122/97           VSVVLSGMVPYTQLRTVPGRGPANLATAFQANGVYWASGIISVGALAGLT
Rv3253c|M.tuberculosis_H37Rv        VSVVLSGMVPYTQLRTVPGRGPANLATAFQANGVYWASGIISVGALAGLT
MAV_4216|M.avium_104                VAVVLSGMVSYTQLKTMPGRGQANLATAFTANGIHWASKIISIGALAGLT
Mflv_4722|M.gilvum_PYR-GCK          VAIVLSGMVSYKDLR---DAESPNLATAFSLNGVDWAAKVISIGALAGLT
Mvan_1740|M.vanbaalenii_PYR-1       VAVVLTGMVSYTELR---DAETQNLATAFSLNGVDWAAKVISIGALAGLT
MSMEG_1838|M.smegmatis_MC2_155      VSVVLSGMVSYRDLKTV-DGESANLATAFAQNGVDWAAKVISIGALAGLT
TH_0471|M.thermoresistible__bu      VSLVLTGMVHYTELR-A-AGENANLATAFAANGIDWAAKVISIGALAGLT
MAB_3599c|M.abscessus_ATCC_199      VTVVLSGMVKYSDLR--VADSHPNLSTAFHLNGVDWAAKVIAVGALAGLT
MLBr_01305|M.leprae_Br4923          SVILLALLLPYSAFK----ASESPFVTFFSKVGFYGAGDLMNIVVLTAAL
                                      ::*: :: *  ::         : * *   *.  *. :: : .*:.  

MMAR_1290|M.marinum_M               TVVMVLMLGQCRVLFAMARDGLLPRQLAKTGARGTPVRITVLVAVVVGAT
MUL_2597|M.ulcerans_Agy99           TVVMVLMLGQCRVLFAMARDGLLPRQLAKTGARGTPVRITVLVAVVVGAT
Mb3281c|M.bovis_AF2122/97           TVVMVLMLGQCRVLFAMARDGLVPRQLAKTGSRGTPVRVTVLVAVLVATT
Rv3253c|M.tuberculosis_H37Rv        TVVMVLMLGQCRVLFAMARDGLVPRQLAKTGSRGTPVRVTVLVAVLVATT
MAV_4216|M.avium_104                TVVMVLMLGQCRVLFAMARDGLLPRALAKTGSRGTPVRITVLVALVVAVT
Mflv_4722|M.gilvum_PYR-GCK          TVVIVLVLGQTRVLFAMSRDGLLPRQLAKTGEHGTPVRITLLVGAVVAVT
Mvan_1740|M.vanbaalenii_PYR-1       TVVIVLVLGQTRVLFAMSRDGLLPRQLAKTGEHGTPVRITLIVGAVVAVT
MSMEG_1838|M.smegmatis_MC2_155      TVVIVLMLGQTRVLFAMSRDGLMPRQLAKTGPHGTPVRTTLIVGGAVAVA
TH_0471|M.thermoresistible__bu      TVVIVLVLGQTRVLFAMSRDGLLPRPLSKTGPRGTPVRITVLVGALVAIA
MAB_3599c|M.abscessus_ATCC_199      TVVMVLMLGQIRVIFAMCRDGLLPRELARTGSHGTPIRITLIVGFLVAVA
MLBr_01305|M.leprae_Br4923          SSLNAGLYATGRVMHSIAINGSGPKFTARMSKNGVPYGGILLAAVICLCG
                                    : : . : .  **:.::. :*  *:  :: . .*.*    ::..      

MMAR_1290|M.marinum_M               ASVFPITKLEEMVNVGTLFAFVLVS-AGVIVLRKKRPD-------LERG-
MUL_2597|M.ulcerans_Agy99           ASVFPITKLEEMVNVGTLFAFVLVS-AGVIVLRKKRPD-------LERG-
Mb3281c|M.bovis_AF2122/97           ASVFPITKLEEMVNVGTLFAFILVS-AGVVVLRRTRPD-------LQRG-
Rv3253c|M.tuberculosis_H37Rv        ASVFPITKLEEMVNVGTLFAFILVS-AGVVVLRRTRPD-------LQRG-
MAV_4216|M.avium_104                ASVFPITKLEEMVNVGTLFAFVLVS-AGVMVLRRTRPD-------LERG-
Mflv_4722|M.gilvum_PYR-GCK          ATVFPIDKLEEMVNIGTLFAFVLVS-AGVIVLRRTRPD-------LKRG-
Mvan_1740|M.vanbaalenii_PYR-1       ATVFPIGKLEEMVNIGTLFAFVLVS-AGVLVLRRTRPD-------LKRG-
MSMEG_1838|M.smegmatis_MC2_155      ASVFPIGKLEEMVNIGTLFAFVLVS-AGVLVLRRTRPD-------LPRG-
TH_0471|M.thermoresistible__bu      ASVFPVGNLEEMVNIGTLFAFALVS-AGVIVLRRTRPD-------LKRG-
MAB_3599c|M.abscessus_ATCC_199      ASLTPIEGLEEIVNVGTLFAFVLVS-AGVIVLRRSRPD-------LPRS-
MLBr_01305|M.leprae_Br4923          VALNAFNPGQAFEIVLSVAALGIIAGWGTIVLCQLRLHKMAKAGIMRRPR
                                    .:: ..   : :  : :: *: :::  *.:** : * .       : *  

MMAR_1290|M.marinum_M               FRAPWVP---VLPIASLCACLWLMLNLTAL-TWIRFGVWLLVGTVIYVGY
MUL_2597|M.ulcerans_Agy99           FRAPWVP---VLPIASLCACLWLMLNLTAL-TWIRFGVWLLVGTVIYVGY
Mb3281c|M.bovis_AF2122/97           FTAPWVP---LLPIAAVCACLWLMLNLTAL-TWIRFGIWLVAGTAIYVGY
Rv3253c|M.tuberculosis_H37Rv        FTAPWVP---LLPIAAVCACLWLMLNLTAL-TWIRFGIWLVAGTAIYVGY
MAV_4216|M.avium_104                FKAPWVP---VLPIASIGACVWLMLNLTAL-TWVRFGIWLVVGTAIYAGY
Mflv_4722|M.gilvum_PYR-GCK          FRTPWVP---VLPILSIIACVWLMLNLTGL-TWIRFSVWMAIGVVLYFVY
Mvan_1740|M.vanbaalenii_PYR-1       FRTPWVP---LLPILAIAACVWLMLNLTGL-TWIRFLIWMAIGVVVYFLY
MSMEG_1838|M.smegmatis_MC2_155      FRTPLVP---VLPVAAILACVWLMLNLTGL-TWIRFLIWMAIGVVIYFLY
TH_0471|M.thermoresistible__bu      FRVPFVP---WLPLAAIAACLWLMLNLTGL-TWVRFLGWMALGLVLYFFY
MAB_3599c|M.abscessus_ATCC_199      FRTPGVP---WLPIVAIVACGWLMLNLAVR-TWLFALSWMVIGVIVYFAY
MLBr_01305|M.leprae_Br4923          FRMPLAPYSGYLTLAFLFAVLVVMAFDKPIGTWTVASLIVIVPALIAGWY
                                    *  * .*    *.:  : *   :*       **      :     :   *

MMAR_1290|M.marinum_M               GRKHSMVGRRQLAEAAMDK--------------------
MUL_2597|M.ulcerans_Agy99           GRKHSMVGRRQLAEAAMDK--------------------
Mb3281c|M.bovis_AF2122/97           GRRHSAQGLRQARESATRRC-------------------
Rv3253c|M.tuberculosis_H37Rv        GRRHSAQGLRQARESATRRC-------------------
MAV_4216|M.avium_104                GYWHSVQGRRDAGEPDRSDALAADPNSPVP---------
Mflv_4722|M.gilvum_PYR-GCK          GRRHSLVARRQRERAGLHTDTP-----------------
Mvan_1740|M.vanbaalenii_PYR-1       GRRHSLVGRRMG---------------------------
MSMEG_1838|M.smegmatis_MC2_155      GRRRSVLATRDTTPTA-----------------------
TH_0471|M.thermoresistible__bu      GRHHSMLGRGMTDISARRTG-------------------
MAB_3599c|M.abscessus_ATCC_199      SRKHSVLGLRVDVEQ------------------------
MLBr_01305|M.leprae_Br4923          SIRKRVMTIARERMGYTGPFPAIANPPVQPSERSHSQNP
                                    .  :