For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MAGRLRTKSVEQSIADTDEPETRLRKDLTWRDLVVFGVSVVIGAGIFTVTASTAGDITGPAIWISFLIAA GTCALAALCYAEFASTLPVAGSAYTFSYATFGEFLAWVIGWNLVLELAIGAAVVAKGWSSYLGTVFGFSG GTADFGSIRLDWGALLIVSIVSLLVAYGTKLSSRFSAVVTTIKVAVVILVVVVGAFYVKAANYSPFIPEP EAGPEGRGADQSLLSLLTGAPGSHYGWYGVLAGASIVFFAFIGFDIVATMAEETKHPQRDVPRGILVSLG VVTLLYVAVSIVLSGMVSYTQLRTVSGGGHANLATAFKANGVYWASGIISVGALAGLTTVVMVLMLGQCR VLFAMARDGLLPRQLAKTGARGTPVRITVLVAVVVGATASVFPITKLEEMVNVGTLFAFVLVSAGVIVLR KKRPDLERGFRAPWVPVLPIASLCACLWLMLNLTALTWIRFGVWLLVGTVIYVGYGRKHSMVGRRQLAEA AMDK
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_1290 | - | - | 100% (494) | cationic amino acid transport integral membrane protein |
M. marinum M | MMAR_3621 | rocE | 7e-79 | 36.69% (477) | cationic amino acid transport integral membrane protein RocE |
M. marinum M | MMAR_2407 | rocE_1 | 3e-76 | 34.11% (472) | cationic amino acid transport integral membrane protein, |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3281c | - | 0.0 | 86.15% (491) | cationic amino acid transport integral membrane protein |
M. gilvum PYR-GCK | Mflv_4722 | - | 0.0 | 74.13% (491) | amino acid permease-associated region |
M. tuberculosis H37Rv | Rv3253c | - | 0.0 | 86.15% (491) | cationic amino acid transport integral membrane protein |
M. leprae Br4923 | MLBr_01305 | ansP2 | 8e-19 | 22.44% (468) | putative L-asparagine permease |
M. abscessus ATCC 19977 | MAB_3599c | - | 0.0 | 68.25% (485) | putative amino acid permease |
M. avium 104 | MAV_4216 | - | 0.0 | 84.25% (489) | cationic amino acid transporter |
M. smegmatis MC2 155 | MSMEG_1838 | - | 0.0 | 72.93% (495) | cationic amino acid transporter |
M. thermoresistible (build 8) | TH_0471 | - | 0.0 | 72.99% (485) | POSSIBLE CATIONIC AMINO ACID TRANSPORT INTEGRAL MEMBRANE |
M. ulcerans Agy99 | MUL_2597 | - | 0.0 | 99.60% (494) | cationic amino acid transport integral membrane protein |
M. vanbaalenii PYR-1 | Mvan_1740 | - | 0.0 | 73.35% (484) | amino acid permease-associated region |
CLUSTAL 2.0.9 multiple sequence alignment MMAR_1290|M.marinum_M MAG--------RLRTKSVEQSIADTDEPETRLRKDLTWRDLVVFGVSVVI MUL_2597|M.ulcerans_Agy99 MAG--------GLRTKSVEQSIADTDEPETRLRKDLTWRDLVVFGVSVVI Mb3281c|M.bovis_AF2122/97 MAG--------RRRMKSVEQSIADTDEPTTRLRKDLTWWDLVVFGVSVVI Rv3253c|M.tuberculosis_H37Rv MAG--------RRRMKSVEQSIADTDEPTTRLRKDLTWWDLVVFGVSVVI MAV_4216|M.avium_104 MAS--------RWRTKSVEQSIADTDEPDTRLRKDLTWWDLVVFGVAVVI Mflv_4722|M.gilvum_PYR-GCK MTQEPVTQAPGRLRLKSVEQSIADTDEPGTKLRKDLNWWDLTVFGVSVVI Mvan_1740|M.vanbaalenii_PYR-1 MVQEPGAQTVGRRRTKSVEQSIADTDEPSTRLRKELNWWDLTVFGVSVVI MSMEG_1838|M.smegmatis_MC2_155 MTT--------RWRTKSVEQSIADTDEPSTRLRKDLTWWDLTVFGVSVVI TH_0471|M.thermoresistible__bu MTD--------RLRVKSVEQSIADTDEPDSRLRKDLSWWDLTVFGVSVVI MAB_3599c|M.abscessus_ATCC_199 MPGS------GLWRTKSVEQSIADTDEPETKLRRDLTWWDLTVFGVSVVI MLBr_01305|M.leprae_Br4923 MAT------LAESPEPKSGASRAGVLGEEAGYHKGLKPRQLQMIGIGGAI * . * *.. : :: *. :* ::*:. .* MMAR_1290|M.marinum_M GAGIFTVTASTAGDITGPAIWISFLIAAGTCALAALCYAEFASTLPVAGS MUL_2597|M.ulcerans_Agy99 GAGIFTVTASTAGDITGPAIWISFLIAAGTCALAALCYAEFASTLPVAGS Mb3281c|M.bovis_AF2122/97 GAGIFTVTASTAGDITGPAIWISFLIAAATCALAALCYAEFASTLPVAGS Rv3253c|M.tuberculosis_H37Rv GAGIFTVTASTAGDITGPAIWISFLIAAATCALAALCYAEFASTLPVAGS MAV_4216|M.avium_104 GAGIFTVTASTTGDITGPAIWVSFVIAAGTCALAALCYAEFASTLPVAGS Mflv_4722|M.gilvum_PYR-GCK GAGIFTITASTAANITGPAISLSFIFAAIACGLAALCYAEFASTVPVAGS Mvan_1740|M.vanbaalenii_PYR-1 GAGIFTITASTAANITGPAISLSFIIAAIACGLAALCYAEFASTVPVAGS MSMEG_1838|M.smegmatis_MC2_155 GAGIFTITASTAGNLTGPAISISFLIAAVACGLAALCYAEFASTVPVAGS TH_0471|M.thermoresistible__bu GAGIFTVTASTAGNITGPAISVSFIIAAIACGLAALCYAEFASTVPVAGS MAB_3599c|M.abscessus_ATCC_199 GAGIFTVTASTAANVTGPAISLSFIMAAIGCGLAAMCYAEFASTIPVAGS MLBr_01305|M.leprae_Br4923 GTGLFLGAGGRLAKAG-PGLFLVYAVCGVFVFLILRALGELVLHRPSSGS *:*:* :.. .. *.: : : ... * . .*:. * :** MMAR_1290|M.marinum_M AYTFSYATFGEFLAWVIGWNLVLELAIGAAVVAKGWSSYLGTVFGFSGGT MUL_2597|M.ulcerans_Agy99 AYTFSYATFGEFLAWVIGWNLVLELAIGAAVVAKGWSSYLGTVFGFSGGT Mb3281c|M.bovis_AF2122/97 AYTFSYATFGEFLAWVIGWNLVLELAMGAAVVAKGWSSYLGTVFGFGNGT Rv3253c|M.tuberculosis_H37Rv AYTFSYATFGEFLAWVIGWNLVLELAMGAAVVAKGWSSYLGTVFGFGNGT MAV_4216|M.avium_104 AYTFSYATFGEFLAWIIGWNLLLELAIGAAVVAKGWSSYLGTVFGFSGGT Mflv_4722|M.gilvum_PYR-GCK AYTFSYATFGEFVAWIIGWDLILEFAVAAAVVAKGWSSYLGTVFGFAGGT Mvan_1740|M.vanbaalenii_PYR-1 AYTFSYATFGEFVAWIIGWDLILEFAVAAAVVAKGWSSYLGTVFGFAGGT MSMEG_1838|M.smegmatis_MC2_155 AYTFSYATFGEFVAWIIGWDLILEFAVAAAVVAKGWSSYLGTVFNFGGGT TH_0471|M.thermoresistible__bu AYTFSYATFGEFVAWIIGWDLILEFSVAAAVVAKGWSSYLGEVFEFAGAT MAB_3599c|M.abscessus_ATCC_199 AYTFSYATFGEFAAWILGWDLILEFSVGAATVAKGWSSYLSTVFGLSSGA MLBr_01305|M.leprae_Br4923 FVSYAREFFGEKAAYVVGWLYFLDWAMTAIVDTTAIATYLHRWTIFTALP ::: *** *:::** .*: :: * . :.. ::** : . MMAR_1290|M.marinum_M ADFGS-IRLDWGALLIVSIVSLLVAYGTKLSSRFSAVVTTIKVAVVILVV MUL_2597|M.ulcerans_Agy99 ADFGS-IRLDWGALLSVSIVSLLVAYGTKLSSRFSAVVTTIKVAVVILVV Mb3281c|M.bovis_AF2122/97 GHLGS-LQLDWGALVIVTLVATLIALGTKLSSRFSAVVTAIKVSVVVLVV Rv3253c|M.tuberculosis_H37Rv GHLGS-LQLDWGALVIVTLVATLIALGTKLSSRFSAVVTAIKVSVVVLVV MAV_4216|M.avium_104 VKFGA-AQLDWGALVIVGGVATLIALGTKLSSRFSAVITGIKVSVVVFVV Mflv_4722|M.gilvum_PYR-GCK AEVAG-FDLDWGALVIIAIVTAILAMGTKLSASVSLAITALKVSVVLLVV Mvan_1740|M.vanbaalenii_PYR-1 TEVAG-FQLDWGALVIIALVTLILVMGTKLSAGVSLAITAVKVSVVLLVV MSMEG_1838|M.smegmatis_MC2_155 MQIGGGLTLDWGALLIIAVVTFLLARGTKISAMVSLVITVIKVSVVLLVV TH_0471|M.thermoresistible__bu TRLGP-ITLDWGALLIIGFVTVLLATGTKLSANVSLAITVIKVGVVLLVV MAB_3599c|M.abscessus_ATCC_199 VHLGA-VKIDWGALLIVSVLTVLLAVGTKLSSRVSLVITTIKVLVVLLVI MLBr_01305|M.leprae_Br4923 QWTLA--------LLALAVVLVMNLISVEWFGELEFWAALIKVCALMAFL *: : : : ..: . .. : :** .:: .: MMAR_1290|M.marinum_M VVGAFYVKAANYSPFIPEPEAGPE---GRGADQSLLSLLTGAPGSHYGWY MUL_2597|M.ulcerans_Agy99 VVGAFYVKAANYSPFIPEPEAGPE---GRGADQSLLSLLTGAPGSHYGWY Mb3281c|M.bovis_AF2122/97 VVGAFYIRAANYSPFIPEPEVQHH---GGGLDQSVFSLLTGAQGSHYGWY Rv3253c|M.tuberculosis_H37Rv VVGAFYIRAANYSPFIPEPEVQHH---GGGLDQSVFSLLTGAQGSHYGWY MAV_4216|M.avium_104 VVGVFYIKRANYSPFIPKPEAGGQ---AKGIDQSVLSLLTGAHTSHYGWY Mflv_4722|M.gilvum_PYR-GCK IVGAFYIKMENFSPFIPAPEPGEA--GGTGAEQSLFSLMTGAEGSHYGWY Mvan_1740|M.vanbaalenii_PYR-1 IVGAFYIKAENFSPFVPAPEEGGS--GGTGTEQSLFSLLTGAEGSHYGWY MSMEG_1838|M.smegmatis_MC2_155 FVGAFYINTANYTPFIPPAESGDGSGGGTGAEQSLFSLLTGAEGSHYGWY TH_0471|M.thermoresistible__bu IVGAFFIKAANYTPFIPPAEAGGE--AGRSLDQSLFSLITGAEGSSYGWY MAB_3599c|M.abscessus_ATCC_199 IVGAFFIKTANYTPFIPPAEAGSS--SRQGLDQSLFSFVAGGSGSQYGWF MLBr_01305|M.leprae_Br4923 VVGTIFLGGR-------YPVDGHN------TGLSLWTSHGGLFPT--GVA .**.::: . *: : * : * MMAR_1290|M.marinum_M GVLAGASIVFFAFIGFDIVATMAEETKHPQRDVPRGILVSLGVVTLLYVA MUL_2597|M.ulcerans_Agy99 GVLAGASIVFFAFIGFDIVATMAEETKHPQRDVPRGILVSLGVVTLLYVA Mb3281c|M.bovis_AF2122/97 GVLAGASIVFFAFIGFDIVATMAEETKRPQRDVPRGILASLGVVTLLYVA Rv3253c|M.tuberculosis_H37Rv GVLAGASIVFFAFIGFDIVATMAEETKRPQRDVPRGILASLGVVTLLYVA MAV_4216|M.avium_104 GVLAGASIVFFAFIGFDIVATMAEETKHPQRDVPRGILASLGIVTLLYVA Mflv_4722|M.gilvum_PYR-GCK GLLAGASIVFFAFIGFDIVATTAEETKVPQRDVPRGILASLGIVTVLYVA Mvan_1740|M.vanbaalenii_PYR-1 GVLAGASIVFFAFIGFDIVATTAEETRNPQRDVPRGILASLAIVTVLYVA MSMEG_1838|M.smegmatis_MC2_155 GLLAGASIVFFAFIGFDIVATTAEETRNPQRDVPRGILGSLAIVTVLYVA TH_0471|M.thermoresistible__bu GLLAGASIVFFAFIGFDIIATTAEETKNPQRDVARGIMATLGIVTVLYVA MAB_3599c|M.abscessus_ATCC_199 GVLAGASIVFFAFIGFDVVATTAEETRNPQKDVPRGIIASLVIVTVLYVA MLBr_01305|M.leprae_Br4923 PLIVVSSGVMFAYAAVELVGTAAGETVEPKKIMPRAINSVIARIAIFYVG ::. :* *:**: ..:::.* * ** *:: :.*.* : ::::**. MMAR_1290|M.marinum_M VSIVLSGMVSYTQLRTVSGGGHANLATAFKANGVYWASGIISVGALAGLT MUL_2597|M.ulcerans_Agy99 VSIVLSGMVSYTQLRTVSGGGHANLATAFKANGVYWASGIISVGALAGLT Mb3281c|M.bovis_AF2122/97 VSVVLSGMVPYTQLRTVPGRGPANLATAFQANGVYWASGIISVGALAGLT Rv3253c|M.tuberculosis_H37Rv VSVVLSGMVPYTQLRTVPGRGPANLATAFQANGVYWASGIISVGALAGLT MAV_4216|M.avium_104 VAVVLSGMVSYTQLKTMPGRGQANLATAFTANGIHWASKIISIGALAGLT Mflv_4722|M.gilvum_PYR-GCK VAIVLSGMVSYKDLR---DAESPNLATAFSLNGVDWAAKVISIGALAGLT Mvan_1740|M.vanbaalenii_PYR-1 VAVVLTGMVSYTELR---DAETQNLATAFSLNGVDWAAKVISIGALAGLT MSMEG_1838|M.smegmatis_MC2_155 VSVVLSGMVSYRDLKTV-DGESANLATAFAQNGVDWAAKVISIGALAGLT TH_0471|M.thermoresistible__bu VSLVLTGMVHYTELR-A-AGENANLATAFAANGIDWAAKVISIGALAGLT MAB_3599c|M.abscessus_ATCC_199 VTVVLSGMVKYSDLR--VADSHPNLSTAFHLNGVDWAAKVIAVGALAGLT MLBr_01305|M.leprae_Br4923 SVILLALLLPYSAFK----ASESPFVTFFSKVGFYGAGDLMNIVVLTAAL ::*: :: * :: : * * *. *. :: : .*:. MMAR_1290|M.marinum_M TVVMVLMLGQCRVLFAMARDGLLPRQLAKTGARGTPVRITVLVAVVVGAT MUL_2597|M.ulcerans_Agy99 TVVMVLMLGQCRVLFAMARDGLLPRQLAKTGARGTPVRITVLVAVVVGAT Mb3281c|M.bovis_AF2122/97 TVVMVLMLGQCRVLFAMARDGLVPRQLAKTGSRGTPVRVTVLVAVLVATT Rv3253c|M.tuberculosis_H37Rv TVVMVLMLGQCRVLFAMARDGLVPRQLAKTGSRGTPVRVTVLVAVLVATT MAV_4216|M.avium_104 TVVMVLMLGQCRVLFAMARDGLLPRALAKTGSRGTPVRITVLVALVVAVT Mflv_4722|M.gilvum_PYR-GCK TVVIVLVLGQTRVLFAMSRDGLLPRQLAKTGEHGTPVRITLLVGAVVAVT Mvan_1740|M.vanbaalenii_PYR-1 TVVIVLVLGQTRVLFAMSRDGLLPRQLAKTGEHGTPVRITLIVGAVVAVT MSMEG_1838|M.smegmatis_MC2_155 TVVIVLMLGQTRVLFAMSRDGLMPRQLAKTGPHGTPVRTTLIVGGAVAVA TH_0471|M.thermoresistible__bu TVVIVLVLGQTRVLFAMSRDGLLPRPLSKTGPRGTPVRITVLVGALVAIA MAB_3599c|M.abscessus_ATCC_199 TVVMVLMLGQIRVIFAMCRDGLLPRELARTGSHGTPIRITLIVGFLVAVA MLBr_01305|M.leprae_Br4923 SSLNAGLYATGRVMHSIAINGSGPKFTARMSKNGVPYGGILLAAVICLCG : : . : . **:.::. :* *: :: . .*.* ::.. MMAR_1290|M.marinum_M ASVFPITKLEEMVNVGTLFAFVLVS-AGVIVLRKKRPD-------LERG- MUL_2597|M.ulcerans_Agy99 ASVFPITKLEEMVNVGTLFAFVLVS-AGVIVLRKKRPD-------LERG- Mb3281c|M.bovis_AF2122/97 ASVFPITKLEEMVNVGTLFAFILVS-AGVVVLRRTRPD-------LQRG- Rv3253c|M.tuberculosis_H37Rv ASVFPITKLEEMVNVGTLFAFILVS-AGVVVLRRTRPD-------LQRG- MAV_4216|M.avium_104 ASVFPITKLEEMVNVGTLFAFVLVS-AGVMVLRRTRPD-------LERG- Mflv_4722|M.gilvum_PYR-GCK ATVFPIDKLEEMVNIGTLFAFVLVS-AGVIVLRRTRPD-------LKRG- Mvan_1740|M.vanbaalenii_PYR-1 ATVFPIGKLEEMVNIGTLFAFVLVS-AGVLVLRRTRPD-------LKRG- MSMEG_1838|M.smegmatis_MC2_155 ASVFPIGKLEEMVNIGTLFAFVLVS-AGVLVLRRTRPD-------LPRG- TH_0471|M.thermoresistible__bu ASVFPVGNLEEMVNIGTLFAFALVS-AGVIVLRRTRPD-------LKRG- MAB_3599c|M.abscessus_ATCC_199 ASLTPIEGLEEIVNVGTLFAFVLVS-AGVIVLRRSRPD-------LPRS- MLBr_01305|M.leprae_Br4923 VALNAFNPGQAFEIVLSVAALGIIAGWGTIVLCQLRLHKMAKAGIMRRPR .:: .. : : : :: *: ::: *.:** : * . : * MMAR_1290|M.marinum_M FRAPWVP---VLPIASLCACLWLMLNLTAL-TWIRFGVWLLVGTVIYVGY MUL_2597|M.ulcerans_Agy99 FRAPWVP---VLPIASLCACLWLMLNLTAL-TWIRFGVWLLVGTVIYVGY Mb3281c|M.bovis_AF2122/97 FTAPWVP---LLPIAAVCACLWLMLNLTAL-TWIRFGIWLVAGTAIYVGY Rv3253c|M.tuberculosis_H37Rv FTAPWVP---LLPIAAVCACLWLMLNLTAL-TWIRFGIWLVAGTAIYVGY MAV_4216|M.avium_104 FKAPWVP---VLPIASIGACVWLMLNLTAL-TWVRFGIWLVVGTAIYAGY Mflv_4722|M.gilvum_PYR-GCK FRTPWVP---VLPILSIIACVWLMLNLTGL-TWIRFSVWMAIGVVLYFVY Mvan_1740|M.vanbaalenii_PYR-1 FRTPWVP---LLPILAIAACVWLMLNLTGL-TWIRFLIWMAIGVVVYFLY MSMEG_1838|M.smegmatis_MC2_155 FRTPLVP---VLPVAAILACVWLMLNLTGL-TWIRFLIWMAIGVVIYFLY TH_0471|M.thermoresistible__bu FRVPFVP---WLPLAAIAACLWLMLNLTGL-TWVRFLGWMALGLVLYFFY MAB_3599c|M.abscessus_ATCC_199 FRTPGVP---WLPIVAIVACGWLMLNLAVR-TWLFALSWMVIGVIVYFAY MLBr_01305|M.leprae_Br4923 FRMPLAPYSGYLTLAFLFAVLVVMAFDKPIGTWTVASLIVIVPALIAGWY * * .* *.: : * :* ** : : * MMAR_1290|M.marinum_M GRKHSMVGRRQLAEAAMDK-------------------- MUL_2597|M.ulcerans_Agy99 GRKHSMVGRRQLAEAAMDK-------------------- Mb3281c|M.bovis_AF2122/97 GRRHSAQGLRQARESATRRC------------------- Rv3253c|M.tuberculosis_H37Rv GRRHSAQGLRQARESATRRC------------------- MAV_4216|M.avium_104 GYWHSVQGRRDAGEPDRSDALAADPNSPVP--------- Mflv_4722|M.gilvum_PYR-GCK GRRHSLVARRQRERAGLHTDTP----------------- Mvan_1740|M.vanbaalenii_PYR-1 GRRHSLVGRRMG--------------------------- MSMEG_1838|M.smegmatis_MC2_155 GRRRSVLATRDTTPTA----------------------- TH_0471|M.thermoresistible__bu GRHHSMLGRGMTDISARRTG------------------- MAB_3599c|M.abscessus_ATCC_199 SRKHSVLGLRVDVEQ------------------------ MLBr_01305|M.leprae_Br4923 SIRKRVMTIARERMGYTGPFPAIANPPVQPSERSHSQNP . :