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VTVRVGINGFGRIGRNFYRALLAQQQQGSADIEVIAVNDITDNQTLAHLLKFDSILGRLPQDVSLEGEDT IVVGGVKIKALEVREGPAAMPWGDLGVDVVVESTGLFTNAAKAKGHLDAGAKKVIISAPATDPDLTIVLG VNDDKYDGSQNIISNASCTTNCLAPLAKVLHDEFGIVKGLMTTIHAYTQDQNLQDGPHKDLRRARAAALN IVPTSTGAAKAIGLVMPELKGKLDGYALRVPIPTGSVTDLTAELAKAATAEEINAAFKAAAEGRLKGILK YYDAPIVSSDIVTDPHSSIFDSGLTKVIDDQAKVVSWYDNEWGYSNRLIDLVALVGKSL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_2239 | gap | - | 100% (339) | glyceraldehyde 3-phosphate dehydrogenase Gap |
| M. marinum M | MMAR_5221 | asd | 3e-06 | 24.24% (231) | aspartate-semialdehyde dehydrogenase Asd |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1471 | gap | 1e-179 | 92.04% (339) | glyceraldehyde-3-phosphate dehydrogenase |
| M. gilvum PYR-GCK | Mflv_3710 | - | 1e-169 | 86.76% (340) | glyceraldehyde-3-phosphate dehydrogenase, type I |
| M. tuberculosis H37Rv | Rv1436 | gap | 1e-179 | 92.04% (339) | glyceraldehyde-3-phosphate dehydrogenase |
| M. leprae Br4923 | MLBr_00570 | gap | 1e-172 | 87.91% (339) | glyceraldehyde 3-phosphate dehydrogenase |
| M. abscessus ATCC 19977 | MAB_2779c | - | 1e-173 | 88.82% (340) | glyceraldehyde-3-phosphate dehydrogenase, type I |
| M. avium 104 | MAV_3341 | gap | 0.0 | 93.51% (339) | glyceraldehyde-3-phosphate dehydrogenase, type I |
| M. smegmatis MC2 155 | MSMEG_3084 | gap | 1e-175 | 89.12% (340) | glyceraldehyde-3-phosphate dehydrogenase, type I |
| M. thermoresistible (build 8) | TH_0426 | gap | 1e-169 | 85.93% (334) | PROBABLE GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE GAP (GAPDH) |
| M. ulcerans Agy99 | MUL_1828 | gap | 0.0 | 100.00% (339) | glyceraldehyde 3-phosphate dehydrogenase Gap |
| M. vanbaalenii PYR-1 | Mvan_2703 | - | 1e-172 | 88.53% (340) | glyceraldehyde-3-phosphate dehydrogenase, type I |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1471|M.bovis_AF2122/97 ------------------------MTVRVGINGFGRIGRNFYRALLAQQE
Rv1436|M.tuberculosis_H37Rv ------------------------MTVRVGINGFGRIGRNFYRALLAQQE
MMAR_2239|M.marinum_M ------------------------MTVRVGINGFGRIGRNFYRALLAQQQ
MUL_1828|M.ulcerans_Agy99 ------------------------MTVRVGINGFGRIGRNFYRALLAQQQ
Mflv_3710|M.gilvum_PYR-GCK MERLLLGWLPSIADDSLIEPEETHVTIRVGVNGFGRIGRNFFRALDAQKA
Mvan_2703|M.vanbaalenii_PYR-1 ----------------MIEPEETDVTIRVGVNGFGRIGRNFFRALDAQKA
MAB_2779c|M.abscessus_ATCC_199 ------------------------MTVRVGVNGFGRIGRNFFRALDAQKA
MSMEG_3084|M.smegmatis_MC2_155 ------------------------MTIRVGVNGFGRIGRNFYRALATQKA
TH_0426|M.thermoresistible__bu ------------------------------VNGFGRIGRNFYRALAAQQA
MAV_3341|M.avium_104 ------------------------MTVRVGINGFGRIGRNFYRALLAQQE
MLBr_00570|M.leprae_Br4923 ------------------------MTVRVGINGFGRIGRNFYRALLAQQE
:**********:*** :*:
Mb1471|M.bovis_AF2122/97 QG-TADVEVVAANDITDNSTLAHLLKFDSILGRLPCDVGLEGDDTIVVGR
Rv1436|M.tuberculosis_H37Rv QG-TADVEVVAANDITDNSTLAHLLKFDSILGRLPCDVGLEGDDTIVVGR
MMAR_2239|M.marinum_M QG-SADIEVIAVNDITDNQTLAHLLKFDSILGRLPQDVSLEGEDTIVVGG
MUL_1828|M.ulcerans_Agy99 QG-SADIEVIAVNDITDNQTLAHLLKFDSILGRLPQDVSLEGEDTIVVGG
Mflv_3710|M.gilvum_PYR-GCK AGKNTDIEIIAVNDLTSNATLAHLLKFDSILGRLPYDVSLEGEDTIVVGD
Mvan_2703|M.vanbaalenii_PYR-1 DGKNTDIEIVAVNDLTDNATLAHLLKFDSILGRLPYDVSLEGEDTIVVGD
MAB_2779c|M.abscessus_ATCC_199 QGVNTDIEIVAVNDLTDNATLAHLLKFDSILGRLPYDVSLEGDDTIVVGD
MSMEG_3084|M.smegmatis_MC2_155 EGKNTDIEIVAVNDLTDNATLAHLLKFDSILGRLPQDVSLEGDDTIVIGD
TH_0426|M.thermoresistible__bu EGKSTDVEIVAVNDLTDNATLAHLLKFDSILGRLPEEVSLEGEDTIVIGS
MAV_3341|M.avium_104 QG-TADIEVVAVNDITDNSTLAHLLKFDSILGRLPYDVSLEGEDTIVVGP
MLBr_00570|M.leprae_Br4923 HG-IADVQVVAINDITDNSTLAYLLKFDSILGRLPHDVSLEEEDTIVVGS
* :*::::* **:*.* ***:************ :*.** :****:*
Mb1471|M.bovis_AF2122/97 AKIKALAVREGPAALPWGDLGVDVVVESTGLFTNAAKAKGHLDAGAKKVI
Rv1436|M.tuberculosis_H37Rv AKIKALAVREGPAALPWGDLGVDVVVESTGLFTNAAKAKGHLDAGAKKVI
MMAR_2239|M.marinum_M VKIKALEVREGPAAMPWGDLGVDVVVESTGLFTNAAKAKGHLDAGAKKVI
MUL_1828|M.ulcerans_Agy99 VKIKALEVREGPAAMPWGDLGVDVVVESTGLFTNAAKAKGHLDAGAKKVI
Mflv_3710|M.gilvum_PYR-GCK TKIKALEVKEGPAALPWGDLGVDVVVESTGIFTKRDKAQGHLDAGAKKVI
Mvan_2703|M.vanbaalenii_PYR-1 TKIKALEVKEGPAALPWGDLGVDVVVESTGIFTARAKAQGHLDAGAKKVI
MAB_2779c|M.abscessus_ATCC_199 HKIKALEVKEGPAALPWGDLGVDVVVESTGIFTARAKAQGHLDAGAKKVI
MSMEG_3084|M.smegmatis_MC2_155 TKIKALEVKEGPAALPWGDLGVDVVVESTGIFTNAAKAKGHLDAGAKKVI
TH_0426|M.thermoresistible__bu TKIKALAIKEGPSALPWGDLGVDVVLESTGIFTDAAKARGHLEAGAKKVI
MAV_3341|M.avium_104 AKIKALEVREGPAALPWGDLGVDVVVESTGLFTNAAKAKGHLDAGAKKVI
MLBr_00570|M.leprae_Br4923 EKIKALAVREGPAALPWHAFGVDVVVESTGLFTNAAKAKGHLEAGAKKVI
***** ::***:*:** :*****:****:** **:***:*******
Mb1471|M.bovis_AF2122/97 ISAPATDEDITIVLGVNDDKYDGSQNIISNASCTTNCLAPLAKVLDDEFG
Rv1436|M.tuberculosis_H37Rv ISAPATDEDITIVLGVNDDKYDGSQNIISNASCTTNCLAPLAKVLDDEFG
MMAR_2239|M.marinum_M ISAPATDPDLTIVLGVNDDKYDGSQNIISNASCTTNCLAPLAKVLHDEFG
MUL_1828|M.ulcerans_Agy99 ISAPATDPDLTIVLGVNDDKYDGSQNIISNASCTTNCLAPLAKVLHDEFG
Mflv_3710|M.gilvum_PYR-GCK ISAPASDEDITIVLGVNDDKYDGSQNIISNASCTTNCLGPLAKVLNDEFG
Mvan_2703|M.vanbaalenii_PYR-1 ISAPASDEDITIVLGVNDDKYDGSQNIISNASCTTNCLGPLAKVLNDEFG
MAB_2779c|M.abscessus_ATCC_199 ISAPASDEDITIVLGVNDDKYDGSQNIISNASCTTNCLGPLAKVLNDEFG
MSMEG_3084|M.smegmatis_MC2_155 ISAPATDEDITIVLGVNDDKYDGSQNIISNASCTTNCLGPLAKVLNDEFG
TH_0426|M.thermoresistible__bu ISAPAKGEDLTVVLGVNDDKYDGSQNIISNASCTTNCLAPLAKVLHDEFG
MAV_3341|M.avium_104 ISAPATDEDITVVLGVNDDKYDGSQNIISNASCTTNCLAPLTKVLDDEFG
MLBr_00570|M.leprae_Br4923 VSAPATDPDITIVFGVNDDKYDGSQNIISNASCTTNCLAPLAKVLHDQFG
:****.. *:*:*:************************.**:***.*:**
Mb1471|M.bovis_AF2122/97 IVKGLMTTIHAYTQDQNLQDGPHKDLRRARAAALNIVPTSTGAAKAIGLV
Rv1436|M.tuberculosis_H37Rv IVKGLMTTIHAYTQDQNLQDGPHKDLRRARAAALNIVPTSTGAAKAIGLV
MMAR_2239|M.marinum_M IVKGLMTTIHAYTQDQNLQDGPHKDLRRARAAALNIVPTSTGAAKAIGLV
MUL_1828|M.ulcerans_Agy99 IVKGLMTTIHAYTQDQNLQDGPHKDLRRARAAALNIVPTSTGAAKAIGLV
Mflv_3710|M.gilvum_PYR-GCK IVKGLMTTIHAYTQDQNLQDGPHGDLRRARAAAINIVPTSTGAAKAIGLV
Mvan_2703|M.vanbaalenii_PYR-1 IVKGLMTTVHAYTQDQNLQDGPHKDLRRARAAALNIVPTSTGAAKAIGLV
MAB_2779c|M.abscessus_ATCC_199 IVKGLMTTIHAYTQDQNLQDGPHKDLRRARAAALNIVPTSTGAAKAIGLV
MSMEG_3084|M.smegmatis_MC2_155 IVKGLMTTIHAYTQDQNLQDGPHKDLRRARAAALNIVPTSTGAAKAIGLV
TH_0426|M.thermoresistible__bu IVKGLMTTVHAYTQDQNLQDGPHKDLRRARAAAINIVPTSTGAAKAIGLV
MAV_3341|M.avium_104 IVRGLMTTIHAYTQDQNLQDGPHKDLRRARAAALNIVPTSTGAAKAIGLV
MLBr_00570|M.leprae_Br4923 IVKGLMTTVHAYTQDQNLQDGPHSDLRRARAAALNVVPTSTGAAKAIGLV
**:*****:************** *********:*:**************
Mb1471|M.bovis_AF2122/97 MPQLKGKLDGYALRVPIPTGSVTDLTVDLSTRASVDEINAAFKAAAEGRL
Rv1436|M.tuberculosis_H37Rv MPQLKGKLDGYALRVPIPTGSVTDLTVDLSTRASVDEINAAFKAAAEGRL
MMAR_2239|M.marinum_M MPELKGKLDGYALRVPIPTGSVTDLTAELAKAATAEEINAAFKAAAEGRL
MUL_1828|M.ulcerans_Agy99 MPELKGKLDGYALRVPIPTGSVTDLTAELAKAATAEEINAAFKAAAEGRL
Mflv_3710|M.gilvum_PYR-GCK LPELKGKLDGYALRVPIPTGSVTDLTAELAKPGTVDEINAAMKAAADGPL
Mvan_2703|M.vanbaalenii_PYR-1 LPELKGKLDGYALRVPIPTGSCTDLTAELAKPGTAAEINAAMKAAAEGPL
MAB_2779c|M.abscessus_ATCC_199 LPELKGKLDGYALRVPIPTGSATDLTVELKKAASADEINAAMKAAAEGKL
MSMEG_3084|M.smegmatis_MC2_155 LPELKGKLDGYALRVPIPTGSVTDLTAELAKSASVEDINAAMKAAAEGPL
TH_0426|M.thermoresistible__bu MPELQGKLDGYALRVPIPTGSATDLTAELAKAATVDEINAAMKAAAEGPL
MAV_3341|M.avium_104 MPNLKGKLDGYALRVPIPTGSVTDLTAELKKPASVEDINAAFKAAAEGRL
MLBr_00570|M.leprae_Br4923 MPELKGKLDGYALRVPIPTGSVTDLTADLSKCVSVNEINAVFQDAAEGRL
:*:*:**************** ****.:* . :. :***.:: **:* *
Mb1471|M.bovis_AF2122/97 KGILKYYDAPIVSSDIVTDPHSSIFDSGLTKVIDDQAKVVSWYDNEWGYS
Rv1436|M.tuberculosis_H37Rv KGILKYYDAPIVSSDIVTDPHSSIFDSGLTKVIDDQAKVVSWYDNEWGYS
MMAR_2239|M.marinum_M KGILKYYDAPIVSSDIVTDPHSSIFDSGLTKVIDDQAKVVSWYDNEWGYS
MUL_1828|M.ulcerans_Agy99 KGILKYYDAPIVSSDIVTDPHSSIFDSGLTKVIDDQAKVVSWYDNEWGYS
Mflv_3710|M.gilvum_PYR-GCK KGILKYYDAPIVSSDIVTDPHSSLYDAGLTKVIDNQAKVVSWYDNEWGYS
Mvan_2703|M.vanbaalenii_PYR-1 KGILKYYDAPIVSSDIVTDPHSSIFDSGLTKVIDNQAKVVSWYDNEWGYS
MAB_2779c|M.abscessus_ATCC_199 KGILKYYDAPIVSSDIVTDPHSSIFDAGLTKVIDDQAKVVSWYDNEWGYS
MSMEG_3084|M.smegmatis_MC2_155 KGILKYYDAPIVSSDIVTDPHSSLYDAGLTKVIDNQAKVVSWYDNEWGYS
TH_0426|M.thermoresistible__bu KGILKYYDAPIVSSDIVTDPHSSLYDAGLTKVIDNQVKVVSWYDNEWGYA
MAV_3341|M.avium_104 KGILKYYDAPIVSSDIVTDPHSSIFDSGLTKVIDNQAKVVSWYDNEWGYS
MLBr_00570|M.leprae_Br4923 KGILKYVDAPIVSSDIVTDPHSSIFDSGLTKVIASQAKVVSWYDNEWGYS
****** ****************::*:****** .*.************:
Mb1471|M.bovis_AF2122/97 NRLVDLVTLVGKSL
Rv1436|M.tuberculosis_H37Rv NRLVDLVTLVGKSL
MMAR_2239|M.marinum_M NRLIDLVALVGKSL
MUL_1828|M.ulcerans_Agy99 NRLIDLVALVGKSL
Mflv_3710|M.gilvum_PYR-GCK NRLVDLVGLVGKSL
Mvan_2703|M.vanbaalenii_PYR-1 NRLVDLVGLVGKSL
MAB_2779c|M.abscessus_ATCC_199 NRLVDLVGLVGKSL
MSMEG_3084|M.smegmatis_MC2_155 NRLADLVALVGKSL
TH_0426|M.thermoresistible__bu NRCVDLVAMVGKSL
MAV_3341|M.avium_104 NRLVDLVALVGKSL
MLBr_00570|M.leprae_Br4923 NRLVDLVGLVGKSL
** *** :*****